There has been much controversy regarding the origin of the Wuhan coronavirus. It appears that both possibilities, naturally occurring or man-made, are legitimate enough to be debated fully. However, although voices on social media are equally strong from both sides, when it comes to written pieces, there is a predominance of scientific literature and other forms of writing that were produced to disapprove the “conspiracy theory”. In contrast, not nearly as much literature or other forms of substantial writing have been put out to describe or argue for the other possibility – this virus is man-made. My goal here is to use scientific evidence and logical thinking to evaluate, and legitimate, the possibility that the Wuhan coronavirus (2019-nCoV, SARS2-CoV, etc.) is of non-natural origin. Importantly, I will base my reasoning on solid, credible evidence; I will exclude any unqualified evidence that may have been thrown in by the Chinese Communist Party (CCP) with an intention to disturb the “investigation” and thereby cover up the truth. My role or perspective here can be considered as a combination of a scientific reviewer, a detective, and a judge on a criminal trial. Why are people suspicious of the origin of the Wuhan coronavirus This has a lot to do with how the sequence of this virus (in other words, its genome) compares with those of related coronaviruses. When comparing sequences, one can compare either gene sequences or protein sequences. For viruses, however, this makes almost no difference as the whole genome of a virus is practically translated into proteins (in fact, a virus typically produces a single polyprotein by translating its entire genome and then cuts this long polyprotein at specific places to produce a set of particular proteins for specific use). Here, we will compare different viruses only on their protein sequences. By doing such a comparison, one can see that the Wuhan coronavirus is about 86% identical to the SARS coronavirus, which caused a pandemic back in 2003. This level of sequence identity basically says that the Wuhan coronavirus could not have come from SARS, something the field agrees unanimously. At the same time, the Wuhan coronavirus is STRANGELY similar to two bat coronaviruses, ZC45 and ZXC21. Overall, the sequence of either of the two bat coronaviruses is 95% identical to the Wuhan coronavirus. In fact, for most part of the genome, such level of identity is maintained or even surpassed. The E protein, in particular, is 100% identical. The nucleocapsid is 94% identical. The membrane protein is 98.6% identical. The S2 portion (2nd half) of the spike protein is 95% identical. However, when it comes to the S1 portion (1st half) of the spike protein, the sequence identity suddenly drops to 69%. This pattern of sequence conservation, between either of the closely related bat coronaviruses and the Wuhan coronavirus, is extremely rare and strange! This is extremely rare because natural evolution typically takes place when changes (mutations) occur randomly across the whole genome. You would then expect the rate of mutation being more or less the same for all parts of the genome. Could other forms of evolution lead to such a strange pattern of sequence identity? Yes, there is one evolutionary event that could lead to drastic changes in only one part of the genome. It is what is called “recombination”. We would defer to the next section to explain why recombination is also practically impossible in this case. For now, let’s fix our eyes on the part that is seeing this sudden drop of sequence identity, the S1 portion of the spike protein. Figure 1. Coronavirus particle with spike proteins (red) decorating its surface. Image from the CDC website (not a photo of a real virus, but a model generated based on scientific knowledge). Spike proteins are the protrusions that you see on the outside of the virus particle (Figure 1). They are literally responsible for the name “corona” as they make the virus look like a “crown”. However, spike proteins are located here for reasons beyond decoration. They are actually the “key” that coronaviruses use to open the “lock” so that viruses can enter our (host) cells. Figure 2 shows the structure of the spike protein of the SARS virus (such structure images are as real as photos of actual people). Given the sequence similarity/conservation here, the spike protein of the Wuhan coronavirus would look pretty much the same, which is indeed confirmed by a recent publication (1). Figure 2. Structure of the SARS spike protein and how it binds to human ACE2 receptor. Pictures generated using the published structure (PDB ID: 6acj) (2). A) Three spike proteins, each consisting of a S1 half and a S2 half, form a trimer. B) The S2 halves (shades of blue) are responsible for trimer formation, while the S1 portion (shades of red) is important for binding human receptor ACE2 (dark gray). C) Details of the binding between S1 and human ACE2. The part of S1 that is important and sufficient for binding are colored in orange, with most crucial amino acid sidechains shown as sticks. This orange piece is presumably what’s “taken out of” SARS spike and “inserted” into a bat coronavirus spike protein, thereby creating a novel human-infecting coronavirus. Three spike proteins have to come together to function properly as the “key”. This three-protein assembly is what they call a “trimer”. To form this trimer, you would need the blue portion of the spike protein, which is referred to as S2 of spike. This S2 part can be regarded as the part of the “key” that you hold with your fingers; it does not actually go into the lock. However, for this “key” to work, S2 has to be there and has to preserve the ability of forming trimers. The other half of spike, the red portion or what is referred to as S1, is responsible for binding the host receptor. S1 can be considered as the portion of the “key” that literally enters the “lock”. It has to fit precisely to the delicate shape of the “lock” (host receptor) so that the “door opening” action can be accomplished. Whether or not a particular “lock” can be opened by a specific “key” is decided exclusively by this S1 part of spike. In other words, S1 of a coronavirus dictates which host(s) or cells the virus can infect. Now you may be able to appreciate what I call extremely strange. While everything else of the Wuhan coronavirus remains almost identical to the two bat coronaviruses, the S1 portion, which dictates which host a coronavirus targets, has changed significantly from the two bat coronaviruses to the Wuhan coronavirus. Let’s zoom in further (Figure 2C) and look at the exact part on S1 that dictates whether or not S1 binds a host receptor (in this case, the human ACE2 protein). This most critical part of S1 is a relatively small stretch of amino acids, labeled in orange in Figure 2C with important residues shown as sticks. This part includes everything needed for interacting with the human ACE2 receptor. You will see below how this segment, known to be unique to the SARS spike and sufficient for its interaction with human ACE2, is practically “copied” over by the Wuhan coronavirus. Figure 3. Sequence alignment of the spike proteins from relevant coronaviruses, including viruses isolated from current pandemic (Wuhan-Hu-1, 2019-nCoV_USA-AZ1), closely related bat coronaviruses (Bat_CoV_ZC45, Bat_CoV_ZXC21), and SARS coronaviruses (SARS_GZ02, SARS). Region marked by orange lines is the segment important for interaction with human receptor ACE2. Crucial residues for interaction are additionally highlighted by a red stick on top. Region marked by green lines is a furin-cleavage site that exists only in the Wuhan coronaviruses but not in any other beta coronaviruses. Alignment was done using the MultAlin webserver (http://multalin.toulouse.inra.fr/multalin/).
Figure 3 is the sequence alignment of the spike proteins from six coronaviruses. Two are viruses isolated from current pandemic (Wuhan-Hu-1, 2019-nCoV_USA-AZ1); two are closely related bat coronaviruses (Bat_CoV_ZC45, Bat_CoV_ZXC21); two are SARS coronaviruses (SARS_GZ02, SARS). By glancing through this figure, you can easily tell that the second half of spike (690 and beyond), namely S2, look pretty much the same for all six viruses. The difference is in the front half (1-~690), or the S1 portion. Now if you look at the top four sequences — the two Wuhan coronaviruses and two bat coronaviruses, you can see that they are largely the same across the S1 half of spike. Only a couple of places are different. However, the details of these differences and the way the human and the bat viruses differ from each other here in S1, in my and many other people’s eyes, practically spell out the origin of the Wuhan coronavirus – it is created by people, not by nature. First important difference is what is highlighted in between two orange lines in Figure 3. Clearly, this part of the Wuhan coronavirus spike differs significantly from those of the bat virus spikes, despite the overall high identity between them. Intriguingly, this same segment of the Wuhan coronavirus resembles, on a great deal, the corresponding piece on the SARS spike protein. Indeed, this is precisely the region highlighted in Figure 2C in orange. As we have pointed out earlier, this segment contains everything needed for human ACE2 interaction. Here, it seems that this critical piece was “copied” from the SARS spike protein and then “pasted” into a bat coronavirus. There are of course differences between these two, which may make it seem unlikely a direct “copy and paste”. However, careful examination shows that all residues essential for binding (orange sticks in Figure 2C and residues highlighted by red short lines in figure 3) are either precisely preserved or substituted with residues of similar properties. At the same time, differences lie mostly at residues non-essential for binding ACE2. Judging from this observation, one can safely envision that not only Wuhan coronavirus spike will bind ACE2 but also it will bind ACE2 exactly the same way that SARS spike does (Figure 2BC). For the two bat coronaviruses here, given how they lack many of the key residues (what is marked by red sticks in Figure 3) for binding human ACE2, it is easy to predict that these two bat viruses would not be able to infect human. The Wuhan coronavirus, while being almost identical to their bat relatives (ZC45 and ZXC21) everywhere else, has somehow “inherited” the critical, short piece from SARS spike to replace the incompetent piece in the bat coronavirus spike. As a result of this miraculous “replacement” in S1 — all key residues preserved and many non-essential residues changed, the Wuhan coronavirus has practically “acquired” the ability to infect humans, something its closest bat relatives do not have. Could natural evolution achieve something this precise and, at the same time, this deceptive??? If you have not been “awed” enough, let’s move on to appreciate magic trick #2. Please look at the region marked by two green lines in Figure 3. Here only the Wuhan coronaviruses contain an additional piece, SPRRA. Importantly, this added piece allows the spike protein to be readily cleaved by a host protease enzyme – furin, a desirable property known to produce more infectious viruses in the case of influenza. Note that no beta coronaviruses in the same lineage (lineage B), except this new Wuhan coronavirus, contain such a furin-cleavage site. Further explanation on why these changes could not have come from nature We have briefly explained why random mutations could not result in the weird pattern of sequence identity between the Wuhan coronavirus and related bat coronaviruses, ZC45 or ZXC21. Let’s dig a little deeper here. Although the spike proteins of different coronaviruses are more likely to differ, greater discrepancy in S1 may only be expected if two viruses have been long separated during evolution and have adapted, through random mutation, to their respective hosts for a long, long time. In that scenario, the overall sequence identity would be low as well. In the present case, however, the sequence identity between either of the bat coronavirus and the Wuhan coronavirus is over 95%, suggesting these two viral lineages must have diverged from each other fairly recently. Therefore, a sequence identity of 69% for the S1 portion of spike protein is simply insane. The S1 of Wuhan coronavirus could not have originated from the S1 of a bat coronavirus, a recent common ancestor that the Wuhan virus shares with ZC45 and ZXC21, through random mutations. Now let me explain why recombination also could not be responsible for the observed pattern. What happens in a recombination event is that one segment of a gene can be “replaced” by a similar segment from another gene. In evolution, recombination events happen much less frequently than random mutations. When recombination happens, however, it often brings abrupt changes to certain areas of the genome. If naturally-occurring recombination event(s) lead to the creation of the Wuhan coronavirus, how would it transpire? First, it would have to take place when an ancestor bat coronavirus, something very similar to ZC45 or ZXC21, co-existed with another coronavirus in the same cell of the same animal. Under extremely rare circumstances, recombination may occur, where a random piece in the ancestor’s genome is replaced by a similar but different piece from the other coronavirus. Importantly, to go from such ancestor to the Wuhan coronavirus, one combination event is not enough. What has to happen is that recombination has to take place twice during the evolution of the Wuhan coronavirus. In one occasion, the ancestor bat coronavirus would have to acquire, through recombination with a SARS-like coronavirus, the precise short segment of S1 that is responsible for human ACE2 interaction (region highlighted in orange in both Figure 2 and Figure 3). In another occasion, the “improved” bat coronavirus would further swap in a furin-cleavage site through recombination with yet another coronavirus that carries a furin-cleavage site between its S1 and S2 of spike. Also, again, given the overall high sequence identity (95%) between the bat coronaviruses and the Wuhan coronavirus, it is reasonable to believe that these two diverged from each other fairly recently. Therefore, both recombination events must have taken place fairly recently as well. Now, we know that SARS crossing over to infect human is a very rare event. To have another SARS-like sequence exist in nature so that the ancestor bat coronavirus can do recombination with is a very unlike event. Not to mention that this SARS-like virus must have a spike that binds ACE2 the same way as SARS and yet the piece of S1 that is most critical for binding ACE2 would differ with that of SARS spike only at non-essential sites. On top of that, furin-cleavge site has not been observed in any beta coronaviruses in the same lineage so far. Although similar furin-cleavage sites have been observed in other coronaviruses, none of them contains the same exact sequence. Therefore, the chance that the furin-cleavage site in the Wuhan coronavirus was obtained through recombination with another furin-cleavage-site-containing coronavirus is very low. Now, what are chances for both of these next-to-impossible recombination events to take place? My answer is NO CHANCE. This Wuhan coronavirus cannot be coming from nature. Why some literature has to be excluded in the analysis Someone who has been following the recent literature on this topic would point out that the above analysis failed to take into account some crucial evidence. Such evidence, coincidentally, supports a natural origin of the Wuhan coronavirus. Then how dare I leave it out in my analysis? The short answer: that “evidence” was very likely fabricated. Please allow me to switch my mode now, from a scientist to a detective or a judge. If we consider this matter as a crime under investigation, then we have so far one big suspect, Dr. Zhengli Shi from the Wuhan Institute of Virology and the biosafety level 4 (P4) lab for virology research. As the top coronavirus expert in China, since the beginning of the outbreak, Zhengli Shi has been singled out as THE suspect who may have created this virus, which somehow leaked out of the P4 lab. Intriguingly, Shi published an interesting paper in Nature a couple of weeks ago (3). There she compared the freshly obtained sequence of the Wuhan coronavirus with those of other beta coronaviruses, which allowed her to delineate an evolutionary path of this new virus. All of a sudden, out of nowhere, she reported a bat coronavirus, RaTG13, which shares high sequence identity with the Wuhan coronavirus. Strikingly, between RaTG13 and the Wuhan virus, the mutational rate is low (or sequence identity is high, 98.5%) for all parts of the genome, including the spike protein. If we have questioned the origin of the Wuhan coronavirus because of the weird pattern of sequence conservation between the Wuhan coronavirus and the two bat coronaviruses, ZC45 and ZXC21, then RaTG13 does not show any concern in that regard. Here, the spike protein is just as conserved as other proteins. From the first look, it seems that RaTG13 belongs to the same small lineage as the Wuhan coronavirus and that the two must share a very recent common ancestor. Such finding strongly suggests a natural origin of the Wuhan coronavirus. This paper reporting the RaTG13 coronavirus (3) is the evidence that I “failed” to take into account in the earlier analysis. According to credible sources, Shi has admitted to several individuals in the field that she does not have a physical copy of this RaTG13 virus. Her lab allegedly collected some bat feces about 7 years ago and analyzed these samples for possible presence of coronaviruses based on genetic evidence. To put it into plainer words, she has no physical proof for the existence of this RaTG13 virus. She only has its sequence information, which is nothing but a string of letters alternating between A, T, G, and C. Can the sequence be fabricated? It cannot be any easier. It takes a person less than a day to TYPE such a sequence (less than 30,000 letters) in a word file. And it would be a thousand times easier if you already have a template that is about 98% identical to the one you are trying to create. Once the typing is finished, one can upload the sequence onto the public database, without being really questioned for its authenticity or correctness. Once uploaded and released, such sequence data becomes public and can be used legitimately in scientific analysis and publications. Then, can this RaTG13 sequence be used as evidence in judging the matter? Well, remember, a central part of the matter is whether or not this Wuhan coronavirus is engineered or created by ZHENGLI SHI. It is Shi, not anybody else, who is the biggest suspect of this possible crime that is grander than any other crime ever committed in human history. Given the circumstances, if the evidence she raised to prove herself innocent is nothing but a bunch of letters recently typed in a word file, should anyone treat it as valid evidence? Unfortunately, in several recent reports, scientists indeed based their analyses on this RaTG13 sequence and thereby reached conclusions such as the Wuhan coronavirus is a result of natural evolution. I hope you now agree that these conclusions could not be trusted because they are based on data that is most likely FABRICATED BY SHI. Now, let us think about this from the other direction. The RaTG13 virus has a highly alarming sequence. Glancing at the sequence of the spike protein of this virus, any expert would immediately realize that this virus resembles SARS in its potential in binding human ACE2 and therefore may very likely be able to infect humans. Shi herself is such an expert. According to Shi, her lab studies bat coronaviruses so that they could someday predict novel coronavirus outbreaks and better prepare the public for such events. If her statement is true, then how could she possibly overlook this extremely interesting finding of RaTG13, something that clearly has the potential to infect humans? If this RaTG13 was discovered SEVEN years ago, why did Shi not publish this astonishing finding earlier? Why did she decide to publish such a sequence only when the current outbreak took place and people started questioning the origin of the Wuhan coronavirus? None of these make sense. All in all, these facts should make people question Zhengli Shi even more in terms of her possible involvement in the matter; she either was directly involved in the creation of this virus/bioweapon, or helped cover it up, or both. Of course, these facts also speak the necessity to exclude this RaTG13 sequence from any scientific analysis. The same goes to the notion that pangolins might be the intermediate host responsible for transmitting the virus from bats to humans. In early Feb, a press conference was held, where three researchers from South China Agriculture University (SCAU) claimed that their recent findings point to Pangolin as a possible intermediate host. First of all, the timing of the press conference is interesting – just when people are saying that bat viruses cannot directly infect humans and an intermediate host must exist (where the viral spike protein would “learn”/adapt to bind an ACE2 similar to human ACE2). When something MUST exist to favor the side of the CCP, this something always miraculously appears, just like Shi’s RaTG13. This time, it is the Pangolin coronavirus. Before even publishing the paper, these researchers showed their evidence – sequence of the receptor binding domain of the pangolin coronavirus that looks almost identical to the Wuhan coronavirus. Again, no live virus exists here, just the sequence (not even released back then). It is the same deal as the RaTG13 case; a person can literally type this sequence out in a few minutes. Therefore, for similar reasons, one has to be extremely cautious and alert that this may again be fabricated by the CCP with an intention to help cover up the truth. Fortunately, the field seems to have excused pangolins. The pangolin coronavirus sequence that was finally released by the SCAU group and another research group in Hong Kong fell short in convincing people about pangolin’s role as an intermediate host (4, 5). This is in part because, according to its sequence, the pangolin coronavirus also does not have the furin-cleavage site. Nonetheless, like RaTG13, these recent papers claiming the role of pangolin as an intermediate host should be discarded (4, 5). In fact, very recently, these SCAU researchers admitted to the press that, upon further analysis of the complete sequence of the Pangolin coronavirus, they also do not believe Pangolin is a possible intermediate host of the Wuhan coronavirus. Some scientific literature that deserves the spotlight We have just laid out the reasons why certain “scientific evidence” should be excluded. Now let us switch over to see why some other scientific evidence deserves our complete attention. First, the two bat coronaviruses, ZC45 and ZXC21, that are STRANGELY CLOSE to the Wuhan coronavirus were collected by a military research lab of the CCP. They published the finding and the sequences of these two viruses back in 2018 (6). I want to emphasize two facts here: 1) if the Wuhan coronavirus was man-made, then it must have been created using ZC45 or ZXC21 as a template; 2) nobody in this world has these bat coronaviruses, except for the CCP as evidenced by this publication. Second, Zhengli Shi co-authored a paper in Nature Medicine back in 2015 (7), where she collaborated with Ralph Baric at the University of North Carolina to show that replacing the spike protein of a non-human-infecting coronavirus with a spike protein capable of binding human ACE2 led to a novel coronavirus that gained the ability to infect humans. Now, what is happening in the Wuhan coronavirus essentially follows the same scheme; the changes, although minimal, are sufficient to turn the bat coronavirus into a virus that can infect humans. The only difference is that, when changes are this subtle, tracing the origin of the virus becomes much difficult. Third, a 2006 publication showed that inserting a furin-cleavage site in the junction region of S1 and S2 of spike of the SARS coronavirus led to much enhanced membrane fusion activity of the virus (8). Although viral infectivity enhancement was not observed in their study using pseudo viruses, presence of such furin-cleavage sites is known to be associated with high pathogenicity in influenza virus infections. Miraculously, this is precisely what is observed in the Wuhan coronavirus (region marked by two green lines in Figure 3). Furthermore, influenza viruses containing such furin-cleavage sites often infect a greater variety of cells and are therefore more likely to target organs in addition to the lung. Now you should recall multiple recent reports describing that the Wuhan coronavirus infects multiple organs, including lung, heart, blood vein, liver, central nerve system, etc. Simple and yet clear logic on how this Wuhan coronavirus may be made by the CCP If you put the pieces together, you should be able to appreciate how easily this virus can be created by the CCP. Obviously, the starting virus template used here, either ZC45 or ZXC21, is owned only by the CCP (6). What they would do then was to modify things such that this bat coronavirus, non-infectious to humans, could be converted to a novel coronavirus that infects humans with high efficiency. They did so by following two published concepts (7, 8): 1) they converted the crucial spike protein to something that follows the scheme of the SARS spike protein so that the virus can target human ACE2; 2) they inserted a furin-cleavage site in between S1 and S2 of spike, which may make the virus more pathogenic. These two concepts are the only ones out there to get such a job done. Yet, miraculously, they are being followed precisely here. If it were mother nature who has created this virus, then mother nature must have studied recent scientific literatures very carefully and followed these key findings faithfully in her work (2, 6-8). Also, let’s go back a little and think why they spend so much time fetching coronaviruses all over the place. Is it really like what they claimed – to understand the potentials of coronaviruses and therefore better predict future emerging coronaviruses? Why didn’t they put as much effort on vaccine research or drug discovery targeting a function/protein conserved in most coronaviruses then? The latter is not only more beneficial to the public but also way easier than predicting emerging viruses. Another possibility, of course, is that they are collecting these things to create coronavirus-based bioweapons. What is the truth? You can make up your own mind. As of me, I am fully convinced that this is a bioweapon made by the CCP. Given all the facts and the logic connecting them as laid out above, it is completely reasonable to argue that, unless the CCP can prove otherwise, the world has all the right to believe that the Wuhan coronavirus was made by the CCP. Reference 1. Daniel Wrapp NW, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan. Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation. Science. 2020. 2. Song W, Gui M, Wang X, Xiang Y. Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog. 2018;14(8):e1007236. 3. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020. 4. Kangpeng Xiao JZ, Yaoyu Feng, Niu Zhou, Xu Zhang, Jie-Jian Zou, Na Li, Yaqiong Guo, Xiaobing Li, Xuejuan Shen, Zhipeng Zhang, Fanfan Shu, Wanyi Huang, Yu Li, Ziding Zhang, Rui-Ai Chen, Ya-Jiang Wu, Shi-Ming Peng, Mian Huang, Wei-Jun Xie, Qin-Hui Cai, Fang-Hui Hou, Yahong Liu, Wu Chen, Lihua Xiao, Yongyi Shen. Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins. bioRxiv. 2020. 5. Tommy Tsan-Yuk Lam MH-HS, Hua-Chen Zhu, Yi-Gang Tong, Xue-Bing Ni, Yun-Shi Liao, Wei Wei, William Yiu-Man Cheung, Wen-Juan Li, Lian-Feng Li, Gabriel M Leung, Edward C. Holmes, Yan-Ling Hu, Yi Guan. Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China. bioRxiv. 2020. 6. Hu D, Zhu C, Ai L, He T, Wang Y, Ye F, et al. Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats. Emerg Microbes Infect. 2018;7(1):154. 7. Menachery VD, Yount BL, Jr., Debbink K, Agnihothram S, Gralinski LE, Plante JA, et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med. 2015;21(12):1508-13. 8. Follis KE, York J, Nunberg JH. Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry. Virology. 2006;350(2):358-69.
2274 Comments
Polo
3/27/2020 01:50:44 am
If true..then dna sequencing can help gene editing to get cure...let us not worry as detective has found answer..all go back home and use this evidence to get cure..bye all and dont worry..thank you detective/judge/biologitst/darwin
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Nerd has power
3/29/2020 07:42:51 pm
Well, it is true that this has nothing to do with how to cure someone with coronavirus infections. But keeping a blind eye and not taking actions may have consequences. If you know someone in your neighborhood is a serial killer, would you feel comfortable giving him freedom and keeping him active? If CCP got away this time, you bet they will throw another one at you next time around. Things can be much worse than coronaviruses, and CCP definitely has more than one thing in their pocket.
Reply
Alberto Rubio Casillas
5/22/2020 08:08:05 am
Dear NERD HAS POWER. I have important information to share with you.
Henri
5/23/2020 04:57:38 pm
Why don't you submit a letter to Cell detailing your analysis? The Editor should send the letter onto Zhengli Shi, allow a reply and publish both together in a future issue. 5/23/2020 06:03:26 pm
I see that you are concerned that the sequences being discussed are merely sequences obtained by analysing materials(eg bat poo), and no live virions or viral nucleic acid are available. In fact much of virology is being done in this way nowadays - the sequences are called metagenomes, they are assembled in computers from short sequences read from various materials - even water.
Kumar
7/6/2020 03:21:00 pm
WHO Visit to China to inquire into Virus Origin (gleaned from reading detailed Research Papers by an anonymous 'Nerd has Power') 7/7/2020 11:23:53 am
Good comments, but this is the moment in history that such research have been speculating about..in situ! Keeping the world's best minds in synch, and in science in a no blame environment is critical. Apart from that, Congress needs to explore EcoHealth.org's publically available 1090's and their auditor's required supporting docs to help unravel their research. This science would help with vaccines and therapeutics. 7/16/2020 09:49:22 am
There have been a few apologetic comments whose authors note; "but I realize this is beyond the scope of this scientific piece." In these historic times, however, our analysis could benefit now and then from a Voltaire who could see that we are living in an age of survival where his "all things are related" thesis might now have a deeper relevance (with certainly the original authors of this blog). It might be that if we now and then see a purpose to function we can develop new relevant sets of discoveries that can further assist our virology, especially now with an additional overlay personal survival but on a shared massive scale. Its an awareness of purpose that comes from our own personal (and according to Voltaire, relevant) level of consciousness.
coolbean
8/2/2020 06:00:38 pm
Nerd Has Power,
Craig Paardekooper
10/5/2020 07:55:18 am
When you know someone in your neighbourhood is a serial killer....
Vivian Wang
10/21/2020 08:15:21 pm
Hi there, I'm a New York Times reporter hoping to reach you about your assessment here. If you're willing, would love to hear from you. Thanks very much.
新新
6/7/2021 02:18:44 am
Even if it is a human-made virus, it is not necessarily made by the Wuhan Virus Laboratory. Before the epidemic of the new crown virus, Wuhan held a military games. Who can say that it is not a virus released by the relevant personnel? This is not the first time the United States has done such things, and it cannot be the last. At least the Americans have done this, and personally will not be surprised. The fake is planted and the thief shouts about the thief,
Rascal
9/4/2021 02:54:42 pm
I would like to understand why it is reasonable to believe ZC45 & ZXC21 are both natural taking from your article;
Errata
9/6/2021 01:41:46 pm
@Rascal
Adrian Gibbs
5/12/2020 04:05:10 pm
I am a long retired virologist living in Canberra Australia. Is there any chance of getting that alignment from you as I would like to have a look at it, but, as a very elderly person, I baulk at the task of assembling and aligning so many long sequences.
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Adrian Gibbs
5/12/2020 04:10:02 pm
Apologies. I am interested in obtaining the nucleotides not the amino acids. Adrian
charly
5/18/2020 03:31:03 am
you can find all published sequence on websites like genbank, eg: https://www.ncbi.nlm.nih.gov/nuccore/MT439597.1 for your concern
Nerd has power
5/18/2020 07:39:45 am
Thank you, chary, for the help.
Geo
8/6/2020 10:36:59 am
The point is if they can make this virus that is hard to detect in who made it and created a weapon. It shows the CCP is making illegal biological weapons of mass destruction. Can you imagine if they did the same thing with small pocs?
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Dave Romain
6/1/2021 07:11:38 am
PLEASE send me a copy of your 'proof' that RATG13 is fake and permission to use it. I intend to include it in a self-published book's chapter on the |Cov2 virus.
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Chris
3/27/2020 06:55:03 pm
about the publications 3,4,5 even if I understand that the dates of publications arrive at the right time just when it was necessary to justify the theory of natural genetic evolution, do you have more convincing elements which could accredit the thesis cheating?
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Na
3/29/2020 05:54:10 am
These papers were published by the Chinese (government) and used as evidence to discredit this theory. 1. These papers came after the initial accusation 2. They are taken by most scientists as evidence to disprove the man made theory. That's all he is telling you - paper was written claiming this was man made. Fake reports were then published by China to disprove this theory, scientists keep citing these papers as a reason this theory is wrong. He is telling you these papers need to be discounted as a reason, plus he is asking why would they have been necessary, all published by CCP scientists.
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Nerd has power
3/29/2020 08:01:13 pm
Technically, I do not have more elements. A lawyer or a judge don't have to show proof to discredit certain evidence, right? It's common sense that the defendant's own words don't count. I am simply saying, given the circumstances (timing of publication being only one, but not the only one), the RaTG13 sequence cannot serve as credible scientific evidence. The same goes to the other two papers on pangolin coronaviruses (there are odd things in the way they acquired their samples, BTW. I can't spend the time describing this though). The CCP should show proof on RaTG13 and pangolin coronaviruses. Again, when the evidence against them is strong, they cannot prove themselves innocent only with their own "words" (sequences).
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Nerd has power ---- corrections made on 3/29/2020
3/29/2020 08:17:42 pm
I updated some things in the article. Someone kindly pointed out two errors in my earlier version. First, in the 2006 paper (reference 8), they actually did not see enhanced viral infectivity. My memory fooled me during my writing. I have corrected this mistake and clarified that insertion of Furin cleavage site lead to greater infectivity and greater cell tropism in INFLUENZA virus, not the pseudo virus in this 2006 paper.
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Debbie
5/15/2020 05:19:56 pm
Dr. Judy Mikovits confirms much of your evidence, and I hope you have watched her interviews online - thank you for your great courage and integrity.
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Andrew M
5/16/2020 01:42:28 am
https://www.snopes.com/collections/plandemic/
Pete Ross
5/21/2020 10:57:02 am
Dr. Mikovits does not refer to the analysis here.
a
4/1/2020 08:08:29 pm
Interesting article.
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Nerd has power
4/6/2020 09:19:13 pm
These sequences are all on the public database (https://www.ncbi.nlm.nih.gov). I will list the accession numbers and you can use them to retrieve the actual sequences of these viruses.
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Piguin
4/6/2020 08:01:13 pm
Nicely written and very hard to dismiss.
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Nerd has power
4/6/2020 09:10:52 pm
I have some thoughts on what methods Shi or others might have used to create it. I might put it into another writing. I know what paper you are referring to though. It's the nature medicine paper published by Andersen, right? His statement that it is easy to detect if a virus is artificially made is laughable. He is either deliberately helping cover things up (his co-author Lipkin is a longterm partner with the CCP) or is simply ignorant about current tools for cloning. Nowadays you can easily edit genes without leaving a trace. Even if it is tedious to remove the trace, wouldn't you do all you can to achieve so when you are making a bioweapon? That nature medicine paper is a shame.
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J17
5/8/2020 06:28:56 pm
Which nature medicine article "The proximal origin of SARS-CoV-2"??? I have computer modeling background as well as virus/bacteria manipulation. I can't believe that made it into nature.
Nerd has power
5/10/2020 04:25:36 am
Thank you for sharing these info. Yes, we were referring to that Nature Medicine paper.
Hugo S. L.
5/10/2020 07:09:02 am
Could you explain if Kristian Anderson's paper is full of flaws then why no other academic papers challenging him and why Dr. Fauci quoted it? A statement made by Anderson to dismiss the lab-manipulation is that the RBD of SARS-CoV-2 is not optimized for affinity with ACE2. I found that argument is somewhat vulnerable if someone only aimed to using lab-manipulation to create a artificial chimeric virus from pangolin and RaTG13(let's ignore its authenticity in nature for now). I found several other weakness in his argument especially when he was interviewed by NYTimes because he could not articulate a persuasive argument to explain how the evolution process could have produced SARS-CoV-2 from pangolin and RaTG13. So I am wondering why there is no academic paper to challenge Anderson's view? Does that mean the whole academics are corrupted because, for example, they all want to find grants from Dr. Fauci or someone else who has supported gain of function research in China? Why did not Ralph Baric say something about it as he was the one who helped China to gain the genetic technology to manipulate virus genes in the lab?
John F Signus
5/10/2020 08:54:39 pm
In fact, when you look at the RBD domain, the underlying nucleotide sequence diverge significantly from the pangolin sequence. Which rule out recent recombination as a possible source of the RBD assuming that sequence was real. (BTW. the "new" Nature paper was a reprint of the 17/02/2020 paper where MP789 first came out, and none of the pangolin strains were submitted to GenBank before 08 Feb 2020. They likely waited for the E gene of SARS-CoV-2 to come out, before using it to finalize the "reconstruction" of the genomes. which explained the fact that they does not show up in an "identical protein report" from the E protein data of any of the SARS-CoV-2 E proteins.)
John F Signus
5/10/2020 08:57:11 pm
For the reference on the Restriction sites, go here
Nerd has power
5/18/2020 08:26:17 am
Thank you, John! Powerful analysis and reasoning as always. I do see restriction sites flanking the RBD, even before I read Yuri's article. I agree that there is a very good chance that the RBD was cloned in using the traditional method of cloning.
Nerd has power
5/18/2020 08:52:27 am
Forgot that ioderESTEl shared this on May 5th:
David Rivard
7/16/2020 09:54:15 pm
Aside from the etiology, but perhaps supporting your general thesis, is the continued forward thrust of information focused upon mortality. WHO is still echoed by most other national authorities. Perhaps the most important information that the public should be focused upon is morbidity. Other than delayed reporting, WHO continues to: 1) Relate C-19 to the common flu. This influenced much of the global public to take it both lightly and politically. 2) Emphasis on deaths, rather than morbidity presented to policy makers to distill the danger, while emphasizing alleviation of respiratory conditions as defining the cure. Note the tens of thousands, and at least 50% of those testing positive, have actually been on their own "recuperation" phase, some since the disease was revealed. There have been support groups established in almost every country. No centralized, (WHO??), or local national authorities, are cataloging long term outcomes (gathering and sharing local epidemiologic data). This population is complaining about being much less vital. Additionally, the only measurable morbidity would be if they were athletic and had past performance or work levels they could measure against (in te scientific world). In fact, a perfect bio-weapon would make populations less vital, with an albeit inevitable, but much smaller but consequential death rate. In concourse it is truly amazing that every country on earth is following the only effective treatment, the science of avoidance, and there is such a dearth of information shared with the public.
Haha
4/7/2020 01:55:50 pm
But Shi's research on collecting virus all over China is funded by ecohealth alliance, via the PREDICT program funded by USAID.
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Nerd has power
4/9/2020 04:44:16 am
Ecohealth alliance may be one of her funding sources. But researchers receive funding from many sources. Shi is funded much much more by the CCP. She is the top expert in virology and leads the top lab at the top facility in China. You can find a bunch of titles that the CCP has given her. If you think she is not under the control of the CCP, then you probably don't really know how things are in China. USAID might have given her some money, but that doesn't mean that they get to watch what her team is doing every minute. However, the CCP can and will. Has Shi obeyed and served the CCP? These titles of hers may tell you a bit on that.
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Well written. I am not a virologist. But can you take a look to see if ihttps://www.pnas.org/content/early/2020/04/07/2004999117 is valid? 70 cent army paid by CCP posted this link almost everywhere in YouTube. Here is what I replied to them:
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Chris
4/11/2020 11:17:15 am
Do you have the YouTube Links ?
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Nerd has power
4/11/2020 11:22:05 am
I saw this paper. You have made a very good point that the sample size in this PNAS paper is too modest. Furthermore, although I'm not a huge expert in bioinformatics, I can say that the way they analyzed these sequences (tracing individual mutations) is very old fashioned and not powerful in today's standards. The combination of these two already diminished their conclusions. But the biggest problem is that they did their analysis by assuming that the RaTG13 virus is the origin of the Wuhan coronavirus (reference 7 in their paper). Their conclusion is reached based on which sequence resembles the RaTG13 sequence more. As you probably know, I am convinced that any scientific analysis based on this RaTG13 sequence should be discarded.
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List Mist
4/11/2020 12:15:23 pm
Thank you for your explanations! Well said! Here are the videos:
Shaun
4/12/2020 12:25:49 pm
This is the most insane paper. I've read the whole thing from top to bottom and have shared it with the world. I am also convinced that this is a bioweapon. The timing is too perfect, everything from the furin-cleavage site to the S1 protein being a SARS variant, and the fact that these "recombination" techniques were previously used by the "Bat Lady" in research *specifically* for simulating potential human coronaviruses.
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Nerd has power
4/12/2020 02:54:07 pm
Thank you for sharing it with others. The matter itself is insane and everybody deserves to know what's really going on.
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Referring to the confusion that arose towards the very beginning of the epidemic re: Seattle coronavirus vs. Wuhan
*Furthermore* if the "recombination" event (i.e. addition of SARS-like spike protein) happened on two separate bat coronaviruses, that would almost *solidify* the fact that it were not by natural selection if those SARS-like spike proteins were similar.
Nerd has power
4/14/2020 09:33:19 pm
Thank you for the clarification. I see your point now. As far as I know, the evidence predominantly supports a single origin of the virus. There appear to be questions of where it originated (although there is actually no doubt that it came from Wuhan), but I don't think any scientific literature really hinted about different strains initiating independently at different places. Again, I think the evidence strongly support a single origin of the pandemic.
Jim jones
5/8/2020 04:31:17 am
Communism is great and has nothing to do with dictatorships. Capitalism dictates. You gave the game away with your scientific bias there. This appears to be about your personal fears and political predudices.You haven't even given a motive for creating this virus or how it benefuts china. Viruses and RNA sequence evolution are far more complex than you make out. Just like your politics.
Nerd has power
5/10/2020 04:38:44 am
Thanks, Jim Jones, for sharing your thoughts. You and I apparently have different views on communism. I just want to bring up one fact. Many countries have converted from communism to capitalism. Have you seen much complaints or people there wanting to go back? I never said capitalism is perfect, but in my opinion it is far more superior than communism. Also, if Kim Jong Un can be interested in making nuclear bombs, we will have to admit that communism is not against having massively disruptive weapons.
David Rivard
7/18/2020 11:44:19 am
I participate in several scientific blogs regarding C-19. Our office also gets up-to-date information from the executive offices of many different countries (typical of many executive offices) and the Health Minister then produces health policies regarding C-19. I have reached my own conclusions from my experiences so far.
sam
5/8/2020 05:20:13 am
Did Zhengli Shi say, "There's more where that came from"? Can you show me where she says that?
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I'm relieved that so many have been eyeballing this virus' origin question! I am not a scientist or biochemist in background but have spent some years learning bits and pieces. My educational tool through this Pandemic has been MedCram.com. They blessedly covered biochemistry basics along this journey as well as what the virus DOES and HOW it is mutating. My husband has been my captive audience throughout our SIP as we both have underlying conditions of concern. I mentioned to him in February-March about how this virus didn't seem to be "acting" like a normal virus we see. I started watching this one in DECEMBER 2019. Our other viruses I've glanced at and just went over "laundry list" of "do's" and on with life. Not so for this one; how would our household prepare and meet this one. I told husband at different times that "this one acts engineered".
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Seek The Truth
4/13/2020 07:19:26 pm
Fascinating...I notice that the comments are "split" (no pun intended)...between here and the Chinese version...I noticed some interesting comments from Elannor D Allens (and your responses) in the Chinese comments section....could you do an 'edit' to incorporate newly provided info/discovery from Elannor D Allens here as well? (I noticed from your comments here...English section...that you made updates as made aware by the commenters)...I think that inclusion of Elannor D Allens' additional info to your write-up would strengthen your assertion considerably...
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Nerd has power
4/14/2020 09:38:37 pm
Great suggestion! I completely agree that comments made by Elannor D Allens are very powerful and supportive of the conclusion here. I will work on translating these over to this English section soon. Thank you!
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Chris
4/16/2020 03:44:13 pm
Yes please translate this comments by Elannor
Greg Felton
8/26/2020 04:37:30 pm
Who is Elannor (Eleanor?) Allens and where did she publish her findings about those 79 codons?
Greg Felton
8/27/2020 07:53:59 am
Who is “Elannor D Allens” and is that spelling correct? a google search turned up nothing. Is it supposed to be Eleanor D. Allen?
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Greg Felton
8/29/2020 10:16:00 pm
STT:
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CCP is NAZI
8/29/2020 10:24:25 pm
Search "Elannor D Allens" in the next door for Chinese comments
Nerd has power
4/16/2020 03:56:59 pm
As noted by Seek The Truth in the comment above, Elannor D Allens made an excellent point in the Chinese comments section next door, which strongly supports the claim that the Wuhan coronavirus is man-made. I have looked into this aspect myself and found it very convincing. Below is this finding and its implications in English. Please note that it is not an exact translation of the comments made by Elannor, although the contents are largely the same.
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Nerd has power
4/16/2020 03:58:21 pm
a bioweapon made by the CCP.
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Ilius
4/24/2020 07:51:18 am
It appeared that there have already been amino acid mutations, acquired during the spread of this virus in humans, that are located at this particular part of the S protein, found in the later samples of this virus which have mutated in humans since it’s contnued spread about a month ago— further indication that such a part of the S protein can indeed tolerate changes and have started to change once it have been spreading intensively in humans. Further proof of the unnatural origin of the original SARS-COV-2 genomes, of which the protein sequences here are all identical with RaTG13.
Nerd has power
4/25/2020 06:12:21 am
Thank you so much for sharing your finding. It is very powerful and strongly supporting the claim that the virus is man-made.
Annette
5/12/2020 04:49:01 pm
A very interesting article and I will need to read it again. I was most interested in the E proteins as they to my understanding cause the immune reaction and possibly the cytokine storm. Please can you comment on the use of E proteins in SARS Cov 2? https://thenativeantigencompany.com/products/sars-coronavirus-envelope-protein-e-coli-2/
Nerd has power
5/18/2020 08:39:52 am
Hi Annette, my knowledge on the E protein came largely from reading this review: 5/8/2020 02:36:22 pm
Thank you for your work.The youtube channel Peak Prosperity has backed up some of your conclusions. He is a trained virologist.
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Nerd has power
5/10/2020 05:05:15 am
Thank you for the comments, John. I have seen one video from Peak Prosperity. It was fantastic. I think it's a believable source of scientific insights into this issue.
Alesh Aras
5/27/2020 06:42:05 am
Where did you get the info that the Peak Prosperity guy is a “trained virologist?” Below is is the public profile I could get from his website:
Greg Felton
8/19/2020 09:26:28 pm
Hi Nerd:
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Greg Felton
8/30/2020 12:21:11 am
Sorry, CPP is Nazi: Beijing tightens grip over coronavirus research, amid US-China row on virus origin: https://www.cnn.com/2020/04/12/asia/china-coronavirus-research-restrictions-intl-hnk/index.html. Exactly, what are CCP trying to hide? The more CCP are trying to hide, the more they are actually exposing the origin of this lab made CCP virus. We definitely need to investigate this thoroughly and hold CCP accountable for their virus. Otherwise, we don't even know how we die one day in the future with more evil virus CCP are so eager to develop!
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Nerd has power
4/17/2020 05:56:14 am
Completely agree. When we say the CCP is anti-human, we risk of understating its evilness. It used to be that not everybody believes this -- because people are generally nice and probably never even tried to comprehend things of such evil nature. But now is the time that everybody be brought to the same page. The CCP must be held accountable. The world cannot afford having communism around any longer.
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Chris
4/17/2020 03:26:39 am
Can I spread your text in France ?
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Nerd has power
4/17/2020 06:10:11 am
Please do! I was disgusted by how some high-profile scientific publications misled people, intentionally or not. That's why I wrote this. I just want more people to know the truth. The more the better. Thank you for your efforts. We are doing the same things.
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Pete Ross
5/21/2020 11:35:23 am
There are experts, including Luc Montagnier, who assert that the SARS-CoV-2 genome contains HIV-like sequences. Thoughts?
Nerd has power
5/23/2020 09:07:18 am
Hi Pete, I have said a few times in the comments that I'm not convinced that there are insertions of HIV sequences into the SARS-CoV-2 genome. Please scroll down to find such comments if you are still interested.
Patric Hausammann
4/17/2020 10:11:36 am
I have checked your work by comparing it to the published sequences on "ncbi" sources of the viruses and I couldn't find any mistake. I think the virus was pretty sure lab made. The mutations do not look natural at all, and I guess some virologes should study more, or they should not take money from the CCP.
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Nerd has power
4/18/2020 09:39:00 am
Thank you very much for your efforts. There are indeed more mutations than what I have focused on describing. The reason I didn't discuss about all mutations is because I wasn't sure how the rest of them might be involved in the actual function. I'm pretty sure about the mutations I did talk about and highlight in terms of how they are important in function and might have been manipulated. There could be more manipulations than what I was able to detect, which may involve the additional strange mutations that you've marked out. But, again, I wanted to focus on things that are more solid and well supported. I don't want to include any less-than-convincing arguments because they may take advantage of those arguments to trash the whole article.
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Patric Hausammann
4/22/2020 01:57:08 pm
Thank you for your appreciated answer. I absolutely agree to use your suggested sequences in your article to prove the claim of man made manipulations. Maybe, there comes out some evidence about the other "strange" changes later.
Greg Felton
8/26/2020 12:23:00 pm
Nerd: I have read that you oppose the HIV origin of the PRRA insert at aa 681. What is the reason for your doubt, and where do you think the insert came from?
Annette
12/12/2021 01:54:52 am
Looks like the discussions on HIV and sARS Cov-2 lab chimera is not rearing its ugly head blaming SA and some sick man as patient ) for omicron! Has anyone explored the Omi genome yet?
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Patric Hausammann
4/17/2020 04:58:09 pm
Here I have a link to the uploaded first 1501 positions of the sequences of WUHAN HU-1, 2019-nCoV, bat CoV ZC45, bat CoVZXC21, RaTG13("invention"), SARS, SARS_GZ02 and MERS in comparison to eachother.
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Jean Claude perez
4/20/2020 09:02:47 pm
> Jean-Claude PEREZ. (2020). “WUHAN COVID-19 SYNTHETIC ORIGINS
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Visitor
4/21/2020 07:12:02 am
Your article appeared to have been deleted. Could you please upload it again?
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Perez
4/21/2020 07:48:22 am
> Jean-Claude PEREZ. (2020). “WUHAN COVID-19 SYNTHETIC ORIGINS
Patric Hausammann
4/22/2020 01:43:41 pm
I couldn't open the link to the article of Mr. Perez too. But I think I've found a working link to his work.
Nerd has power
4/23/2020 07:01:19 am
Dear Mr. Perez, thank you very much for sending your published work. I have to admit that the mathematics involved in your study is way beyond me. Although I am in agreement with your conclusion that the Wuhan coronavirus is a result of human manipulation, I'm completely disqualified to comment on this part of your study.
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Simen D arreighher
4/21/2020 02:20:53 am
This is something that you may wan’t to see.
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Nerd has power
4/23/2020 07:25:05 am
Thank you for your work. What you have posted are all quality info in my opinion. Among them, the most intriguing is the link to ferrets and tree shrews. These really may have been the lab animals that they used in the course of selecting and improving viral strains, which should have followed their initial manipulation of the genome via molecular cloning.
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John F Signus
4/25/2020 04:45:51 am
The nucleotide sequence coding for the E protein in Bat-Cov-ZC45,ZXC21 and RaTG13 are exactly the same, indicative of an extremely well conserved gene that have not seen a single mutation during the entire 5 years of divergent evolution across the two very distantly related viruses(as indicated by the vast differences in the S protein) —but curiously, the first sample of SARS-CoV-2 show 3 nucleotide substitutions within this gene (without changing the amino acid sequence), and newer examples of SARS-CoV-2 have shown amino acid substitutions within up to 4 different locations within this protein, in merely 3 months of human-to-human transfer. An indication of an extremely high mutation rate within the E gene, and the permissivity of the E protein toward changes in it’s amino acid sequence.
Nerd has power
4/25/2020 06:09:47 am
Wow!!! Powerful evidence! Thank you so much for sharing. I completely agree with your analysis. The E protein being identical among ZC45, ZXC21, RaTG13, and initial samples of SARS-CoV-2 is highly suspicious to begin with. Now amino acid changes in E protein have already been observed in such a short period of human-to-human transmission. It's just such a strong proof.
John F Signus
4/25/2020 10:30:36 am
Closer analysis of RaTG13 and ZC45 have also revealed that the identicality of the E gene on these two viruses being highly suspicious.
Nerd has power
4/28/2020 08:20:31 am
Thank you again for these excellent analyses. I looked at the nucleotide conservation myself for the E proteins. There are actually two single nucleotide substitutions between ZC45/ZXC21 and RaTG13, although they did not lead to amino acid changes. It's a small error, which of course does not alter your whole logic or conclusion.
John F Signus
4/29/2020 01:59:56 am
Did you use ZXC21? I am not aware of that sequence. I did a Multalin on the sequence ZC45 and RaTG13 and the nucleotide sequences were exactly the same. If the 2 substitutions on the ZXC21/ZC45-RaTG13 were on the ZXC21 sequence, then it will be a more solid evidence that the RaTG13 N protein gene was a direct clone from ZC45. Further evidence that RaTG13 was unnatural.
John F Signus
4/29/2020 02:47:45 am
Sorry for the mistake. I think I compared the wrong sequence.
Nerd has power
4/30/2020 07:37:39 am
Thank you for the update. Please don't apologize. Your analysis was brilliant. I'm still working on that updated version of the article. I will show a sequence alignment/comparison by following your suggested strains. That, in combination with what you have described for E proteins, is very convincing.
Silverfox
4/22/2020 01:27:10 am
I I have read your analysis carefully and I do find that it stands completely.
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Nerd has power
4/23/2020 07:37:36 am
Thank you for your comments. I was made aware of Dr. Li's work, although I did not get to read it in full. I think her work is very relevant in developing therapeutic and treatment strategies, which may or may not hint the origin of the virus. My two cents.
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Pete Ross
5/21/2020 01:47:51 pm
Anyone address this type of contention?
Lois Geerhardt
4/8/2021 07:04:46 pm
Hi, Sir, you have only shown that a stretch of amino acids of S1 looks like “copied” from the SARS spike protein and then “pasted” into the Wuhan coronavirus. Don't you think that, to confirm your hypothesis, you should verify that the same does not hold true for the S1 segment from other species?
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Nerd has power
4/23/2020 08:03:53 am
Thank you. It's a very good question. Most coronaviruses don't contain this "copy/pasted" piece in their S1. The exceptions are SARS (of course) and about two SARS-like bat viruses. However, none of these SARS-like viruses "copy/paste" this critical piece as precisely as what's seen in the Wuhan coronavirus (residues important for SARS spike/ACE2 interaction all preserved/conserved and changes only occur at non-essential locations).
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MZ1234
4/24/2020 12:40:39 am
A leading Russian microbiologist has claimed the coronavirus is the result of Wuhan scientists doing 'absolutely crazy things' in their laboratory.
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List Mist
4/24/2020 11:08:13 pm
Well, https://www.newsmax.com/navrozov/china-biological-russia/2009/09/17/id/335042/ written over 10 years ago speaks well regarding whether the Chinese scientists created variants of the virus with or without malicious intent.
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Nerd has power
4/25/2020 05:46:13 am
Thank you! I obviously agree that this virus is a result of human manipulation. However, I don't think this Russian expert should so confidently say that they did it "without malicious intent". In my opinion, the evidence speaks the opposite.
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Nerd has power
4/25/2020 06:33:27 am
Thank you for bringing up this article. It actually proves two of my predictions. First, it proves that the S1 of the Wuhan coronavirus (SARS-CoV-2 as everyone else prefers) binds ACE2 the same way as SARS S1 does. I predicted this by just looking at the sequence comparison. As I mentioned in the article, there appears to be a well-plotted "copying" of a critical piece in S1 of SARS and then "pasting" it into a template virus to create the S1 of SARS-CoV-2.
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NotA~A
4/25/2020 02:51:35 am
From the comment section of this article: https://www.virology.ws/2020/02/20/pangolins-and-the-origin-of-sars-cov-2-coronavirus/
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Nerd has power
4/25/2020 06:46:00 am
Thanks for sharing! Whoever made the comment has captured something very interesting, which successfully eluded the public's attention.There seems to be a reason that Zhengli Shi does not bring this up herself -- she would struggle to explain it one way or the other. Again, great catch!
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Hydride
4/25/2020 12:19:20 pm
bits and pieces. RaTG13 used for gene assembly, the optimize to get SARS-CoV-2. How could an RdRp from an alphacoronavirus (phylogenetic distance so high that even recombination (require homologous sequences flanking the RNA fragment)was considered impossible with betacoronaviruses.) wind up in a “Natural” bat Betacoronavirus?
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Bryan
5/7/2020 01:56:43 pm
Great find. This is real evidence that RaTG13 did exist prior to 2020 and wasn't completely made up.
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Veltra
5/10/2020 10:31:55 pm
Did look at the publication--and they did not actually post any of the sequence data in regard to RaBt4991/RaTG13. Except a single figure of the phylogenetic tree. We can still not prove that RaTG13 is not manipulated.
Bryan
5/11/2020 07:45:16 am
It doesn't prove that the rest of the genome wasn't made up, but they did share at least part of the replicase gene in 2015 https://www.ncbi.nlm.nih.gov/nuccore/KP876546.1/
Biohazard0808
6/9/2020 03:30:05 pm
First of all, when looking at the "viruses" isolated from bats, it should be noted that no replication-capable viruses were actually sampled in most cases. As Shi's Science paper from 2005 describes, not a single active virus was isolated from the first 408 samples including blood, respiratory and faecal swaps. P.D. said in a recent interview that a total of 15,000 samples were taken to date just to find a few replicable viruses. Apparently, everything else was "reproduced" from RNA fragments, reverse transcribed into cDNA and re-assembled. In fact bat SL-CoV-WIV1 was the first viable CoV that was isolated in 2013 (described in nature paper). From only about 1.5% of the (mostly faecal samples) a positive RT-PCR was obtained according to the first paper in Science (although sampling methods have improved since then - in 2013 there were 23% that delivered at least a positive PCR result).
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NotA~A
4/26/2020 07:54:47 am
something is moving:
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Nerd has pwer
4/26/2020 07:47:23 pm
Thanks for sharing. The more we dig, the more people digging it, the sooner we will get to the bottom of this. We are moving along.
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Sir, thank you for your patience and consideration. I have a few questions. First, that the S1 of the SARS-CoV-2 binds ACE2 the same way as SARS S1 (or as the S1 segment from other species, not only bats, does) does not prove that binding is necessarily infectious. For example, does SARS-civet infect humans? Second, isn't the fact that the high level identity for most part of the genome with that of bat coronaviruses is not maintained in the S1 segment of the Wuhan coronavirus only a prove of how nature has learned to preserve the ability to bind ACE2, whatever random mutation or recombination may take place? Others seem convinced that SARS-CoV-2 might be a recombinant virus between viruses closely related to SARSr-Ra-BatCoV RaTG13 and pangolin-SARSr-CoV/MP789/Guangdong/2019. Indeed, coronaviruses have been shown to have a high frequency of recombination (Adv Virus Res, Volume: 48, Pages: 1-100, 1997). Their tendency for recombination and high mutation rates may allow them to adapt to new hosts and ecological niches, including natural recombination in coronavirus associated with human infection. Last, but not least, you suspect that a colleague of yours has only recently published a paper about RaTG13 infectiousness, of which she was aware SEVEN years ago, which has no other explanation than her involvement in spike protein engineering. How could she know that without having checked human infection?
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Nicholas V Thartkins
4/26/2020 09:31:18 am
(Translated from the Chinese section of this blog, originally by Dithionite)
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Nicholas V Thartkins
4/26/2020 10:03:15 am
Especially L449K, of which a major steric clash from the much longer Lysine side chain would shave off at minimum 150KJ/Mol of binding affinity of MP789/SARSCoV2 to the pangolin ACE2 receptor -- bringing the affinity from 699Kj/mol typically seen in Coronaviruses to it's native host ACE2, down to at most 550KJ/Mol.
Nerd has power
4/26/2020 08:31:24 pm
Thank you so much! Great translation and analysis!
Nicholas V Thartkins
4/30/2020 05:22:44 am
The units should be Kcal/mol not Kj/mol.
Nerd has power
4/26/2020 08:27:43 pm
I will try to answer each one of your questions.
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Nerd has power
4/26/2020 10:20:24 pm
Forgot to comment on the high frequency of recombination in coronavirus. Yes, it is a true fact. However, that does not mean that any type of change in coronavirus evolution is reasonable. I did the best I can to explain how I think recombination is unlikely to lead to the weird pattern of sequence similarity between SARS-CoV-2 and ZC45/ZXC21. Anyone can of course make up his/her own mind on this claim. Again, please check the comment made on Apr 16th. That one, in my opinion, is a very strong evidence.
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Metabisulfite
4/26/2020 08:15:33 am
https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full.pdf
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Metabisulfite
4/26/2020 08:22:55 am
Also, leronlimab, a CCR5 antagonist, seems to work well for treating COVID-19.
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Nerd has power
4/26/2020 08:42:40 pm
Thank you for your comments. I have answered this in the Chinese section, I believe. I am actually skeptical whether there are any insertions of HIV sequences in the SARS-CoV-2 genome. I have read this preprint article when it first came out and was not convinced by the evidence within. According to my own blasting, those "inserted" pieces do not necessarily come from HIV.
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Kathy
4/26/2020 08:31:31 am
KP876546 is a SARS-related betacoronavirus
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Nerd has power
4/28/2020 08:37:23 am
Thank you for sharing these!
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Silverfox
4/27/2020 11:42:20 pm
Hi again, I read every day comment on your article, and I realy appreciate your analyse. Then I would like to submit you a new article, from Jean-Claude PEREZ and Luc MONTAGNIER published in preprint on april 26.
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Nerd has power
4/28/2020 08:46:53 am
Thank you for sharing these articles. Unfortunately, I have been a little busy the last few days and did not get to read them. Hopefully I will get to later this week. I may not be able to offer much insights though because I don't have the proper knowledge in Mr. Perez's research area and methods.
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Nerd has power
5/3/2020 06:34:02 am
Sorry for the delayed response. I did get to read Mr. Perez's work here. It's different from the one he shared with us earlier. Although I'm in agreement with Mr. Perez on the conclusion that the Wuhan coronavirus is of a synthetic origin, I again would have to admit that I'm not the best person to judge such an article. Based my limited knowledge, I would say that the sequences suspected as insertions are all on the shorter end, which tend to make things inconclusive in terms of where (HIV or other origins) they could be from. I did find the higher mutational rate of the EIEs over the whole genome very interesting. This could be a sign of artificial manipulation. On the other hand, it seems to me that these EIEs are located within Orf1b and the Spike regions (correct me if I'm wrong as I'm not 100% sure I have this right). I believe that these two regions of the coronavirus genome do tend to see higher frequency of mutations. This could just be a natural trait of coronavirus evolution. Of course, this may also mean that this bioweapon did not go through exhaustive optimization/passage before being put on the real mission and therefore is now adapting to the new host.
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Tholix
4/28/2020 04:15:24 am
https://www.researchgate.net/publication/340786428_COVID-19_Pandemic_Its_Origin_Implications_and_Treatments
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Nerd has power
4/28/2020 08:49:06 am
Thank you for sharing the info!
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Ana Salinas
5/1/2020 05:32:23 am
Hi Nerd has Power, I would like to talk to you a little further. Would you give me your mail? thanks in advance!
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Nerd has power
5/3/2020 06:46:53 am
Do you mind sharing your thoughts here in the comments section? I would prefer public discussions. The communications here have been great. Thank you!
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Edix
5/1/2020 07:58:27 am
I did the Homology based modeling analysis on the MP789 RBD and the pangolin ACE2 receptor.
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Exins FG Adam
5/2/2020 07:18:54 am
https://drive.google.com/open?id=1opowSQgcvpSb58piY1mvSf4AIGzpjssS
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Chris
5/2/2020 10:52:18 am
Thank you. Tell us if the paper is accepted or not
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Exins FG Adam
5/2/2020 06:59:29 pm
Sorry but biorxiv.org have rejected my paper--citing that is should be sumbitted on a peer-reviewed journal instead of on BiorXiv.
Nerd has power
5/3/2020 07:51:28 am
Thank you for posting it here too. Great work! Too bad that they turn it down at bioRxiv. I saw some other preprints on this place: zenodo.org. Maybe you can give it a try here?
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Exins FG Adam
5/5/2020 04:30:13 am
https://zenodo.org/record/3786451#.XrFN4YijeUk
Nerd has power
5/7/2020 09:55:17 am
That's great! Congrats on the preprint! Thank you for doing it. 5/2/2020 01:52:45 pm
I’d love to discuss this with you. I would love to make a video summarizing your take. It’s very similar to mine and others. Harvard2Thebighouse has done some of the first coverage in Jan.
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Nerd has power
5/3/2020 07:35:08 am
Great video! I love the concept of journal club on a bike. You properly shattered that Nature Medicine paper.
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ioderESTEl
5/2/2020 10:09:02 pm
You may want to check this as well:
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Nerd has power
5/3/2020 08:05:49 am
Thank you for sharing these info. I love the article written by Yuri Deigin. It's so thorough, rich in information, and in the end convincing (although I'm already convinced). I learned quite a lot of details and side stories reading it. The only thing I would be picky about is that he was too scientific in his discussions and did not properly factor in how evil the CCP can be. It's certainly not Yuri's fault. The CCP certainly want to and can make bioweapons. They are also professional on covering things up, using all sorts of resources. Here they chose to use, among other things, fake science (RaTG13, Pangolin coronaviruses, Nature Medicine paper by Andersen and Lipkin, etc).
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ioderESTEl
5/5/2020 02:00:39 pm
Some other science community commentary on the original Nature Andersen, et al paper.
Nerd has power
5/10/2020 05:43:18 am
Thank you so much for sharing these. So glad to see prominent scientists coming out publicly to challenge that Nature Medicine paper and the claim that the virus is of natural origin. I thoroughly enjoyed reading these two articles as they articulated many of the same things that have been in my mind for a long time. I focused on describing the logic and evidence of human manipulation, but I had similar thoughts on how they might have worked on creating this artificial virus. Directed evolution could easily be involved.
Nerd has power
5/3/2020 12:48:17 pm
As you may have noticed, there are new pages added to this site. I just published an updated version of the earlier article on GNEWS (a great news platform created by the heroic Miles Kwok). However, there were quite a few editing errors of my GNEWS article. So I'm posting this updated article here too (RATG13 IS FAKE). This new version benefited tremendously from the insightful comments made here, especially by Ellannor D. Allens and John. F. Signus. I have acknowledged their contributions at the end. Thank you!
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Viennah K Erchus
5/3/2020 06:59:55 pm
A takedown on the recent study claiming that the furin site may have been from HKU9 through "Co-infection"
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Viennah K Erchus
5/3/2020 07:01:08 pm
Could it be ZC45/ZXC21 and HKU9 in humans?
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Nerd has power
5/4/2020 05:23:27 am
Thank you for the thorough and powerful analysis! I think you successfully dismissed all possible routes of its natural occurrence. However, they can always fall back to say that there might be a perfectly identical furin-cleavage site in a bat virus out there that we just haven't discovered yet (don't be surprised if one of the Chinese research labs will soon publish such a sequence). The burden is definitely heavier on our side, but it's becoming more apparent. The truth will come out.
Eitcherius F Asken
5/5/2020 03:55:23 am
https://www.youtube.com/watch?v=uZUJhKUbd0k
Nerd has power
5/5/2020 05:19:24 am
Thank you for posting this YouTube video. I listened to the whole thing. It's wonderful. I apparently agree with you and Chris in this video that the natural occurrence of the Furin-cleavage site is impossible. What I did not appreciate in full earlier was that all the viruses containing a similar (no one has the exact) sequence are less than 40% identical to SARS-CoV-2. That makes the chance of such a site arising from natural recombination close to zero. It's a great finding. Of course, that family tree, portraying SARS-CoV-2 being the one in that half of the branch that has a furin-cleavage site, is also very powerful. Better than what words can describe. Overall, the claim that this furin-cleavage site is a result of lab manipulation is becoming rock solid.
Ornius
5/3/2020 07:47:38 pm
Someone kindly reminds me that such co-infection experiments have already taken place in IMMUNOCOMPROMISED BAT CELL LINES by Zhengli Shi. So a recombination during cell passage may also be a plausible origin of the Furin site, in addition to deliberate insertion.
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Nerd has power
5/4/2020 05:39:12 am
Completely possible. They could introduce it in several different ways and animal passage might very likely be involved. The method that was actually used may only be revealed by the one(s) who did it.
Viennah K Erchus
5/4/2020 10:57:40 pm
I have seen bad comments on your Gnews article.
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Nerd has power
5/5/2020 05:24:27 am
I certainly can! Thank you for providing these sequences. I don't think I get to update the GNEWS article, but I can update the version here by adding an amendment. I will leave a comment on GNEWS and direct people to check it out on this blog. I hopefully will get it done by the end of tomorrow. Thanks again!
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Nerd has power
5/10/2020 05:52:34 am
Hi Viennah, sorry for the delay, but I had finally updated the article per your suggestion. Thank you so much for retrieving these sequences and put them into the right format. It made creating the figure so much easier. I will leave comments under the GNEWS article and encourage people to migrate over here to see the updated info.
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Kathy
5/6/2020 03:25:27 am
I have a question: the furin cleavage site sequence is inserted in SARS-CoV-2 in a way that produces a split of the codon for Serine in the pangolin sequence MP789 and Ratg13. Please see fig.1 here:
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Firox TD Jackinson
5/6/2020 04:45:26 am
It maybe that the insert was made in that way. Site-directed mutagenesis experiments are very conservative about the number of nucleotides they can insert/delete, and would normally be designed in such way that it minimizes the change to the original genome while achieving the goal of the operation. Making the result look as natural as it can. So if the one who made the insert found out that by splitting the Serine codon one can minimize the overall change toward the entire genome and make it look more natural than just inserting in-frame, then it will be such an insert that ended up being chosen.
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Firox TD jackinson
5/6/2020 05:30:56 am
Looked up the codon table-- and the +1 insert is very easy to design. the codon for A/Alanine can have any nucleotide at the 3rd position, so just keep the 3rd position of the original S679 at the last 1bp of the PRRA. So leave it unchanged & save 1 nucleotide on your primer. The Codon for Serine TCA/TCT can also have any nucleotide at the 3rd location and it's not in-frame with the P-R-R-A. So just change it to anything else.
Firox TD Jackinson
5/6/2020 05:42:26 am
4^8=65536.
Kathy
5/6/2020 07:52:31 am
Thank you very much for checking this and the links!
Nerd had power
5/6/2020 12:39:26 pm
Thank you for the analysis and explanation. I did not get to read the original article, but I don't think there is anything that you did not cover :). The Youtube video was excellent. It made it so crystal clear that the furin-cleavage site was not out of natural evolution.
Firox TD Jackinson
5/7/2020 05:49:54 am
Thank you for your analysis. Technically the insert could be either +1 or +2 out of frame, or is a 12nt in-frame insertion+1 silent mutation. With the +2 insert however, it would make the needed primer 2nt shorter than the in-frame 12, by shifting the reverse primer by -2. reducing the total absolute extra length need for synthesis to 10. Unlikely to have slipped past the eyes of the designer/software when designing the insert/primers.
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Firox TD Jackinson
5/7/2020 06:02:41 am
Protein being of Non-natural origin is more than 3833/3834, or more than 99.9739%
NasCinx
5/6/2020 04:01:58 am
It seems that a lot of debate was going on a short 370bp partial RdRp sequence known as RaBtCoV/4991, claiming that it was the first sample of RaTG13. However, this does not remove any of the questions surrounding RaTG13.
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Nerd has power
5/6/2020 12:40:28 pm
Exactly!
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Kathy
5/9/2020 02:35:51 pm
Now we know it:
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Nerd has power
5/10/2020 06:27:23 am
Thank you for sharing these, Kathy. I invited Peter under that tweet to come over and see how "RATG13 IS FAKE". I would love to see his comments coming up in this section.
RV
5/7/2020 12:10:59 pm
I find your hypothesis very compelling and I also find an article arguing the opposite very compelling. What do you think? You both argue your cases very well and as a layman I don't know who is right. I hope you will look at it and consider a rebuttal.
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Alix
5/7/2020 07:02:07 pm
See Viennah K Erchus’s comment on the takedown of that hypothesis.
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Firox TD Jackinson
5/9/2020 09:07:03 pm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075523/
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Nerd has power
5/10/2020 10:24:32 am
Thank you, Alix and Firox. Very nice info and analysis!
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NM
5/7/2020 01:26:08 pm
hopefully you have seen this ....
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Rikaja
5/7/2020 01:58:00 pm
Amazing research. Please, try to publish in a peer-reviewed journal for scientists to see.
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Bryan
5/7/2020 02:10:06 pm
One thing that really throws off estimations of similarity between RaTG13 and SARS CoV2 is the weird mutation pattern. Almost all the SNPs are C<->T or A<->G changes. This is not the mutation profile of replication errors. A recent article makes a pretty good case that this could be the result of deamidation by host cell APOBEC or ADAR proteins.
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Argin
5/7/2020 05:41:34 pm
Technically, this will not affect the mutation rate analysis as the same holds true for ZC45/ZCX21 and the rest of RaTG13/CoV2.
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Bryan
5/9/2020 09:11:04 am
That's not quite right. I'd assume enzymes like APOBEC edit any position in a codon equivalently. But the type of mutations done by APOBEC or ADAR are transitions (APOBEC: T<->C and ADAR: A<->G). Generally in the 3rd, or "wobble" position of a codon, transitions do not change the encoded amino acid, whereas a transversion does. Transitions will still usually change the encoded amino acid if they occur in the 1st or 2nt position of a codon. Interestingly, I just did a quick analysis of the SARS-CoV2 spike protein and there is a somewhat higher percentage of Cs and T/Us in the 3rd codon position (62% C/T content) compared to the first (41%) or second (54%). If APOBEC randomly converts any C/T, it's more likely to occur an the wobble position just because of the abundance of C/Ts. Overall, this means that APOBEC mutations are much more likely to cause silent (synonymous) mutations than more random mechanisms (like coping errors).
Argin
5/10/2020 08:15:41 am
However, when you look at the mutation rates between the rest of RaTG13/CoV2, the Syn/Nonsyn ratio is completely normal near 5:1. If an RNA modification system was involved, why it would selectively modify just the S2 but not the rest, like ORF1ab, M or N?
Argin
5/10/2020 08:26:36 am
62% compared to (54%+41%)/2 was not that high. Assuming only conversions from APOBEA/ADAR possible, it will only cause a minor (6.526-to-1 instead of 5-to-1 "natural") deviation from the established pattern. Not the complely unnatural 44-to-1 ratio as we see here. Even factoring the RNA modification, this ratio still return a chance of 2.76e-6 for the entire S2 protein to be natural. a 1 in 361730 chance.
Argin
5/10/2020 04:54:37 pm
In fact, if APOBEC and ADAR causes more synomynous changes than normal mutation processes in the viral RNA, we should have seen a change in the codon preference between RaTG13 and SARS-CoV-2--the ratios of codon usage should have changed since an elevated level of synomynous changes over non-synomynous changes will bias the codon preference of SARS-CoV-2 significantly from "the extreme CpG deficiency of SARS-CoV-2" when compared to RaTG13.
Nerd has power
5/10/2020 06:25:36 pm
Can't agree more. Wonderful discussion and analysis. Thank you!
Exid
5/10/2020 08:11:15 pm
It also appeared that the CpG deficnency in RaTG13 and SARS-CoV-2 was ancestral-- it likely happened BEFORE the two viruses branched away on the evolutionary tree. So Whatever kind of modification system at work in the ancestor have stopped working when RaTG13 and SARS-CoV-2 came to place.
Nerd has power
5/12/2020 02:18:42 pm
Thank you, Exid. Great finding! Unless they argue that SARS-CoV-2 directly crossed over from bats, they would not be able to answer why the codon bias is the same between SARS-CoV-2 and RaTG13.
Bryan
5/14/2020 10:33:56 am
Argin,
Nerd has power
5/18/2020 09:18:30 am
Hi Bryan, I would like to comment on the last point you raised. I agree that the 5:1 ratio is very raw. It's a general trend due to the purifying pressure that most proteins experience in evolution. You are also correct that different protein/sequences, when facing different selection pressures, would exhibit different dS/dN ratios.
Bryan
5/19/2020 03:51:34 pm
Hey Nerd Has Power,
Argin
5/20/2020 06:21:11 am
See Farvous's comment on the next door. the ORF1ab dS/dN is a normal 6.22:1. not a sign of the extreme kind of purifying selection or an APOBEC/ADAR transition jockey here. also, ORF1ab is more purifying for viruses that have different host than S since the main mutations are on the S to mediate host switching. While in the same host the ORF1ab is less purifying than the S since the S will be more conserved to maintain host adaptation.
Nerd has power
5/23/2020 12:32:14 pm
Thank you, Argin, for bringing up Farvous' analysis.
John F. Signus
6/18/2020 07:29:46 am
https://drive.google.com/file/d/1Xp1zBf2d-hu32XSKkyJ7UBOg9ZHuAURS/view?usp=sharing
Bryan
7/5/2020 08:11:48 pm
Hey Nerd, sorry it's taken me a while to respond.I don’t think it’s a reasonable assumption to have uniform mutation frequencies or syn/nonsyn ratios throughout a viral genome. That might be an alright first null hypothesis, but if one actually want’s to make a case that a genome isn’t natural (either that it’s engineered or that it’s made up) you really need to look to nature, not a naïve assumption of uniform mutation rates. Is the relationship between SARS-CoV2 genome and RaTG13 different than the relationship between other related coronaviruses?
Exidos B freeman
5/7/2020 09:13:23 pm
https://zenodo.org/record/3786451#.XrTZjCV6uEc
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Bryan
5/9/2020 08:20:31 pm
I'll look at that link, is it a similar argument to that posted here?
Exidos B freeman
5/9/2020 08:52:31 pm
Well, My analysis is done on the nucleotide level-- Even assuming a highly conserved protein, the underlying nucleotides should have seen synomynous changes since it shouldn't affect the Amino Acid sequences, therefore it shouldn't affect anything at all. The point is that The newer "Evidence" (e.g. RaTG13, pangolins, etc.) Had too little synomynous substitution rate when compared to the rate that is seen in the rest of the genomic sequence. Which isextremely unusual, and seems to point out a common E sequence that were used for the fabrication of the "evidences", which were all obtained from short sequence metagenome sequencing data.
Nerd has power
5/10/2020 06:42:35 pm
Great finding on the severe discrepancies of the nucleotide sequence identity on E vs. whole genome! It seems that the more different ways we compare RaTG13 to other viruses, the more evidence we could find supporting its fabrication. Thanks, Exidos!
Farvous
5/11/2020 12:01:15 am
Did a BLAST on the ORF1ab polyprotein on RaTG13 to SARS2-- the Syn/nonsyn ratio is about 6.22:1.
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Nerd has power
5/12/2020 02:31:17 pm
Thank you for the work! Again, they must have manipulated the sequence of Spike more than anything else --- they know people would scrutinize the RBD of S1 more than anything. However, they apparently spent too much time "editing" RaTG13's RBD that they had to be stingy about non-synonymous mutations when "editing" the sequence of S2. It is really nice to confirm that the syn/non-syn ratio is largely normal when other parts of the genome are being compared between RaTG13 and SARS-CoV-2. Thanks again!
Jogn F. Signus
6/18/2020 07:31:17 am
Also, may want to try SARS/YNLF31C.
Exid
5/16/2020 06:52:58 pm
However,
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Exid
5/20/2020 06:00:53 am
Therefore, nomatter how your hypothesis claimed, it should *Not* give an overal skewed dS/dN to >9:1 . but this ratio is not observed for the overall genome of RaTG13/SARS-CoV-2. Therefore, the APOBEC/ADAR hypothesis is still invalid on a mutation rate standpoint.
Jon1717
5/7/2020 02:22:27 pm
Ok silly question, can you help me reproduce the sense / nonsene graph? I'm not getting the same results. I don't get the flatline for nonsyn mutations.
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Exip
5/7/2020 06:00:37 pm
Maybe you accidentally made the alignment out-of-frame. Look at the assembly and locate the CDS for the “S” gene. Make sure you start with “AUG”. Your sequence may be misaligned.
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Bryan
5/14/2020 09:20:36 pm
Those are the right sequences. I think you are missing the alignment step. The input to SNAP needs to be aligned on a codon basis. I use a program called seaview that allows me to view the DNA sequences as proteins, align them (Clustal or Muscle), and then switch back to the DNA view. Then put the DNA seqs into SNAP. If you put unaligned sequences into SNAP, It will all be full of random syn and nonsyn mutations as soon as you hit any INDELs. In this case, once you hit amino acid 681 (SARS-CoV2's polybasic cleavage site) it'll all be noise.
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Mitch
5/7/2020 03:29:24 pm
While I appreciate your efforts, I agree with those who have pointed out that blog publishing is probably not the first choice of those who would like to have their information fully vetted by experts in the field.
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Nerd has power
5/10/2020 06:58:27 pm
Thanks for the suggestion. I don't mind having the article judged by anybody, including reviewers/experts. Apparently, the comments/discussions we got here are excellent. I have tried to reply to each one before, but I started to feel a bit overwhelmed and may not be able to keep up -- some comments are made by people who are real experts (I am an half expert) and there are too many of them now. You don't get this in a peer-review process. Reviewers' comments are typically not seen by public -- they can be unreasonable (more frequently so than you might expect) and yet the public wouldn't know. Here, on the open platform, you see everything. I personally believe that this article is being judged harsher than a manuscript undergoing peer review. If I were you, I will feel safer about the contents as they are being constantly validated.
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Alesh
7/5/2020 11:06:28 pm
Good point 5/7/2020 05:03:44 pm
I ran your analysis of SARS Cov 2 with RaTG13 by downloading a FASTA alignment file MN996532.1 x NC_045512.2.aln from NCBI virus and loading it on SNAP. I got a slightly different curve. I was wondering if I could send it to you?
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Fight Against CCP
5/7/2020 05:35:31 pm
CCP dog has finally arrived. Why cannot you just disprove it? Barking around only shows your weakness!
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Kathy
5/7/2020 10:36:23 pm
Articles that clearly state an artificial origin for SARS-CoV-2 do not have a chance to be published. There is a huge censorship on the topic. What else we have that to make preprints and meet on these platforms? I am grateful that they exist.
I am no native English speaker.An alternative view on it.Very impressive article and comments.I tought I was intelligent but you guys put me in my place at least in biology.I was suspicious about the way they said it was from nature in the first place because it break out where the only lab is of mainland china and where they do research with this kind of virus.Also patient zero not found on market which plays role in nature speculation.I think there were lots of infections on market because a lot of people come together there, just that. If objective mind the researchers should lower the odds of naturel accuring already a bit on that.But I often see that people have bias against a possible truth they dont like.Also scientist. When there is social research with differnt gender, race for example and they dont like the result they come with very long explanation of the least controversial possible explanation they can find.When it is 99,999 % chance from lab and you bring evidance which makes it 99,99999% from lab they would hold on to nature version.I saw some bias against bio-weapen in myself some time ago. When I realised humans are capable of nuclear weapons I changed my mind and not longer saw accident as 99% the couse.
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Nonameneeded
5/7/2020 11:51:44 pm
Can someone do an in silico analysis of the role of the proline in the PRRA insert. What happens when this is removed or substituted with alanine? Asking because this may kink the secondary structure and increase solvent and protease exposure.
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Kathy
5/8/2020 11:38:48 am
....If the virus can even sustainably infect bats, or causes a very harsh disease that would obviously be incompatible with this being the natural host. This is worth looking into.
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nonameneeded
5/8/2020 12:33:15 pm
Not sure why they did it in the fruit bats rather than intermediate horseshoe bats (and pangolins), which are the hosts that are bandied about.
Nerd has power
5/10/2020 07:09:22 pm
Agree that some lab really should look at whether RaTG13 can infect its alleged natural bat host. I thought about this too -- what if it can't??? Maybe Zhengli Shi will blame it on the incompetency of the ones who did the test. I'm sure that, if she does the test in her lab, the infection will be "successful" and yet the bat will die very quickly -- leaving just the remains which contains the RaTG13 virus in the proper organs.
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Malcolm
5/8/2020 01:03:01 am
Re: RATG13 IS FAKE
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Malcolm
5/8/2020 05:30:56 am
Calculations if anyone is interested.
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Kathy
5/8/2020 05:48:53 am
Can you exclude that RaTG13 is real but "just" edited? There is a possible record of if named BtCoV4991
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Malcolm
5/8/2020 07:05:33 am
BtCoV-4991 is a very small fragment (370 nucleotides or 123 amino acids) of the ORF1a gene, collected at the same time and place that RaTG13 was claimed to be found. A blast search gives a 100% match with RaTG13 and 98.92% with SARS-CoV-2, which is only a three nucleotide difference.
Mitch
5/8/2020 06:53:58 am
I understand that some of those coming here are used to an environment of strict censorship. But unless you are ready to declare that the journals covering virology have peer-review committees which are all corrupt, it seems contradictory to point to evidence of scientific fraud which is (1) obvious and (2) incapable of being published in a peer-reviewed journal.
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Kathy
5/8/2020 08:37:05 am
I am aware that BtCoV4991 is a short sequence, but as you say, it was collected the same year, by the same group and in the same place as RaTG13 is supposed to. Coincidence? Perhaps. I am a fan of the pangolin theory, with the switch of the RBD of RaTG13 (edited) with the one from the pangolin CoV plus a furin cleavage site from another bat living in the same cave (I am still hunting this). An evolutionary study with the potential to develop a global corona-vaccine gone wrong. Interesting that these two articles were sponsored bathe same grant (Baric+Shi).
John F Signus
5/9/2020 04:13:42 am
The paper is actually a repost of a February 17 preprint under the same title. Parts that concludes that the pangolin coronavirus have no furin cleavage site were redacted. As well as the full S gene that is very distant.
John F Signus
5/11/2020 02:49:01 am
Read the Nature article more thoroughly.
John F Signus
5/11/2020 06:24:50 am
Which was used for "Assembling" the genome. It's very easy for the researchers to mistake a contamination from SARS-CoV-2 itself, or other "more similar sequences" that they pulled off "The raw reads from public databases" as something that is more close to SARS-CoV-2, and mistakenly assemble it into the resulting genome.
Troy T Dow
5/8/2020 11:59:34 am
I wish John F Signus would comment again. I'm worried his real name is Bing Liu, murdered in Pittsburgh on May 2nd.
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J17
5/8/2020 07:23:23 pm
I talked to my lab guy and he agrees with the Yuri article. He wonders how often furin sites are so perfectly added to close relatives without any extra junk. So I'm going to be doing analysis of closely related RNA viruses w/ and w/o furin to see how often that happens.
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Anonymous
5/9/2020 12:01:24 am
If the argument is that the COVID-19 E protein mutated over time and that E proteins mutate at a constant rate within bat populations, why then are ZC45 and ZXC21 identical? Or am I missing part of the logic?
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John F Signus
5/9/2020 03:27:53 am
ZC45 and ZXC21 are very closely related—while RaTG13 or CoV2 are very distantly related to ZC45/ZXC21.
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Anonymous
5/9/2020 04:11:50 am
Sorry, John F. Signus, but I still do not understand the logic of your argument. Although they were collected 1.5 years apart, because ZXC21 and ZC45 are "related," they should have not undergone any mutation and, therefore, are identical. RaTG13 is not related to them, but has an identical E protein. How does the short term mutation of COVID-19 fit into that argument? That is, would not any E protein mutation also apply to ZXC21 and ZC45, which would then show a sequence difference? Thank you in advance for a clarification.
John F Signus
5/9/2020 11:26:51 am
ZC45/ZXC21 was 98% similar. They are more similar to each other than RaTG13 to SARS-CoV-2. Also collected at the same site. The evolutionary distance is very short between ZC45/ZXC21. Much shorter than ZC45/ZXC21->RaTG13/CoV2. See the RaTG13 article to see how short their distance was, Evolutionarily. The reason that E was suspicious, was, due to the fact that there were closer Bat-CoVs and SARS-CoV, with a different E protein and genetic similarity higher than RaTG13->ZC45/ZXC21.
FreeFreedomain
7/2/2020 07:14:03 pm
John, thanks for the detailed explanation. I'm trying to understand it. If ZXC21 and ZC45 are 97% similar and CoV2 is 95% similar to both ZXC21/ZC45. Why having identical E protein when similarity is 97% is ok and natural, but when similarity is 95%, then it's nearly impossible to have identical E? There is only 2% difference between these two cases.
John F Signus
5/10/2020 02:51:09 am
https://zenodo.org/record/3786451#.XrFN4YijeUk
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John F Signus
5/10/2020 03:00:28 am
And whenever a chimeric/synthetic coronavirus was engineered, the particular E protein sequence was used for it's construction. It may then acquire the (unnaturally few) synomynous mutations after brief passage in cell culture.
John F Signua
5/10/2020 03:11:01 am
"By comparing the ORF1ab polyprotein with a very distantly related coronavirus that is not on the same lineage, SARS, "
Nerd has power
5/10/2020 07:36:56 pm
Thank you, John. Fantastic analysis and reasoning as always!
Physics Guy
5/11/2020 02:44:00 pm
Hi John F Signus, Nerd has Power and others. As my name suggests I am not a biologist, but I follow this discussion with interest. As an outsider I can in any case see that a moratorium was tried on research that creates viruses with pandemic potential
John F signus
5/11/2020 05:01:38 pm
The actual problem it that the E protein is a protein coding gene—it is Significant in the sense that it is Both a distinct part of Coronavirus biology and Coronavirus reverse genetic systems. It is not a “random sequence”. Other sequences are non-significant, therefore they Can not be compared to a plausible synthetic origin By engineering.
Physics Guy
5/12/2020 01:02:48 am
Great. I don't follow your last bit 1/(29855*6)=1/179130. My estimate for the "look elsewhere effect" was just a maximum. How many of these locations like the E-protein one are there, for which you could a priori expect something "fishy" if the virus is not natural? Roughly the "look elsewhere effect" says that if there are for example 4 of such a priori locations and you find something fishy for 1 of those 4, then you divide your final probability by 4.
John F Signus
5/13/2020 12:01:56 am
Well, there is only ONE E gene in SARS-CoV-2. the only other suspicious protein is the first part of S2. using the "look elsewhere" effect, for the specific sequence (btw it was an 225bp sequence out of 29855, not a 75bp sequence), the maximum should be 1 in 6*(225/29855)=796.16, or based on the only 2 identical proteins of significance, 1 in (1655/2)=827.5.
K. Evangeline Luk
5/9/2020 02:37:34 am
I'm not sure if @Raoul89573207 that tweeted me this blog was you, but you need to come onto our Riot server.
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Eva Celia
5/9/2020 11:23:36 pm
Have you read about the odd pneumonia outbreak in Virginia back in summer 2019 https://www.nbcwashington.com/news/local/health-officials-to-give-update-after-respiratory-illness-sickens-dozens-at-virginia-retirement-community/135890/ and also this from France in Nov 2019 https://www.scmp.com/news/china/society/article/3083599/france-had-covid-19-november-hospital-says-after-analysis-chest
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Kathy
5/9/2020 11:28:55 pm
COVID RIDDLE Fears coronavirus arrived in Europe in OCTOBER ‘when French athletes at World Military Games in Wuhan brought it home
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Fight Against CCP
5/9/2020 11:41:06 pm
Well done, Kathy! :) Such a large scale virus couldn't have originated from anywhere else and hidden for so many months until the first largest outbreak in Wuhan. That's why COVID-19 = CCP Originated Virus Infectious Disease-19. As you can see, CCP propaganda and dogs are everywhere. They would not know how evil CCP are until they themselves become CCP's victims.
Fight Against CCP
5/9/2020 11:48:54 pm
Here are more to add to your list:
Nerd has power
5/10/2020 07:46:59 pm
Agree. Given how easily this virus spreads and how little people know back then about having to use masks to stop it, there is no chance that France (or any other place that the CCP wants to mis-label as the "true origin") could have avoided community spread back then.
to go deeper
5/10/2020 12:21:12 am
But summer comes before fall
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CCP is NAZI
5/10/2020 09:58:57 am
Have you actually compared its sequence with CCP Virus' sequence side by side? If so, why don't you bring its sequence here to let virus specialists verify? Even look at it from a non scientific perspective view, with such a high infectious rate that CCP virus has, why nothing happened in U.S. afterwards until after Wuhan lock down? Interestingly, CCP tried their very best to help this deadly CCP virus spread as fast and wide as possible all over the world by silencing 8 doctors like Li Wenliang , by destroying all virus samples, by stressing it's preventable and controllable, by denying the fact about human to human transmission, by letting people out from Wuhan to everywhere in the world but not within China? Were CCP able to prevent and control it? Exactly, what's CCP's hidden agenda? Well, aren't these https://www.newsmax.com/navrozov/china-biological-russia/2009/09/17/id/335042/ and https://www.theepochtimes.com/did-chinas-plan-to-destroy-the-united-states-backfire_3223117.html enough to tell CCP's world domination goal?
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Jane
5/18/2020 05:37:49 am
Did you read this?
CCP is NAZI
5/10/2020 11:16:38 am
Where is the bat woman and the virus queen - Shi Zhengli? Why don't you invite her here to see what she has to say? Where is the Patient Zero, Huang Yanlin? Is she already dead or hidden? Why did Wuhan P4 lab take her picture down while still leaving her name there? Look at her with her lab mates on 2018 New Year Day: https://www.youtube.com/watch?v=NVzne_ZQ0Vo I'm sure that CCP really has hard time to find someone who not only looks like her, but also has a virologist's knowledge. Further, U.S. has the best CCP virus tester to test her to see if she was infected with or is currently infected with CCP Virus.
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detailfreak
5/10/2020 02:07:13 am
Two tracks to follow now that we know that RaTG13 is BtCoV4991:
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Lincolin
5/10/2020 06:31:43 am
Did a BLAST on all of them.
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Lincolin
5/10/2020 07:00:55 am
There were a total of 8 Spike proteins Listed there.
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Lincolin
5/10/2020 07:46:28 am
Therfore, there were still no Spike gene dequence data, or any pieces of data other than the tiny 370bp BtCoV/4991 Partial RdRp, of RaTG13 that were published, or confermed, before the pandemic.
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Dartagnan
5/12/2020 03:00:04 pm
Wow... so the gene fragment that codes for the RdRp of the virus is conveniently put out there 3-4 years ago. Just enough time for someone to develop an effective RdRp Inhibitor drug (like remdesivir or likely something even more effective given in pill form which is not public yet) that can be given prophylactically to high level officials or others you want to favor. These people will be protected from infection or treated quickly once the pandemic hits, while the rest of the world is physically and economically paralyzed. Gilead's tenofovir, which is the adenine analog chain terminator cousin of remdesivir, is already used this way as a reversetranscriptase inhibitor prophylactic for HIV. Then folks like Peter Daszak can go on 60 Minutes and say that their dangerous GOF research helped lead to life saving breakthroughs like remdesivir...
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CCP is NAZI
5/12/2020 03:35:08 pm
No surprise. CCP's evilness is way more than what you can imagine. CCP's Nazi conduct are doomed to be severely punished. I wish more people can wake up to knock down CCP with whom the world would not have any peace.
Javier
5/10/2020 07:46:23 am
Hello. Excellent work here in this blog. Thanks.
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John F Signus
5/10/2020 07:51:03 am
The article claimed that the Furin site arose in humans-- However, if that was the case, why the very first sample of SARS-CoV-2 already had the exact perfect PRRA furin cleavage site? Why there were never a detection of a "Progenitor virus" in humans that lacked this site? If it arose in humans, it should have already been detected. no intermediate CoV2 W/O PRRA is a clear indication that id did not arise that way.
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John F Signus
5/10/2020 08:03:41 am
From phylogenetic data and the comment made by Firox TD Jackinson, We already knew that a furin site will not survive nor persist in wild animals for Spike gene that is more than 40% homologous to SARS-CoV-2. So it can't arise in an animal. And there were no detection of a "intermediate virus" in humans that is near-identical to SARS-CoV-2 while laching the PRRA. Therefore, it can't arise in animals and did not arise in humans, leaving the only possible source of the furin site as either deliberate insertion or lab-based passage. Cell passage may cause it to arise in the lab in that mechanism, however. (the AIV example cited by the paper is actually in-vitro passage data) Since cell culture lacked an immune system, they will not eliminate the furin-cleavable spike immediately like wild animals, but since they are not humans, the intermediate will be shielded inside a lab and therefore will not be discovered in actual, live humans. explaining the lac of an intermediate in humans.
Javier
5/10/2020 09:12:50 am
Very interesting reply John.
John F signus
5/11/2020 05:20:05 pm
The problem is that both the FCS containing precursor and the RBD containing precursor are potent enough to cause an epidemic in humans. More so than SARS. We already knew that the FCS is not tolerated in wild animals for betacoronavirus spike protein genes that is more than 40% homologous to SARS-CoV-2. So it can’t arise in that way.
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IdoNotLikeCherries
5/10/2020 09:36:32 am
Anther cherry on the cake:
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Nerd has power
5/10/2020 08:21:50 pm
Fantastic efforts, everybody! This place is becoming alive, with all your insights and excellent analyses. I must admit that they are much better than what I was able to offer in the original article. Please keep adding it.
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In 2013-15, Zhengli Shi and colleagues thought the Rhinolophus sinicus bats they had found in Yunnan caves had a Coronavirus capable of infecting human lungs.
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Marco Belladama
5/11/2020 05:37:25 am
I'm a system integrator.... need to download the genome and a little guide to remake the picture like in this post
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Sam
5/11/2020 09:52:18 am
Does the existence of BtCoV/4991 RdRp - a fragment of a viral genome that got published in 2016, 4 years before RaTG13, and seems the same as the RatG13 sequence published in Jan 2020 affect your argument (that RatG13 is a fake) at all? https://www.ncbi.nlm.nih.gov/nuccore/KP876546
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Simen
5/11/2020 08:03:47 pm
The existence of RaBtCoV/4991 actually does not prove anything. The sequence is only 370bp in length and everything elve were still not published until 27-JAN-2020 . The only other reference of RaBtCoV/4991 was a single figure in that 2019 paper, which published no sequences. Notably, if what they claim was true on the S protein, we should already seen the RBD of RaTG13 being published before. We didn't.
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Nerd has power
5/12/2020 03:22:37 pm
Thank you, Simen! Agree with your analysis.
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Sam
5/13/2020 03:35:14 am
Thank you so much for your interesting reply and for taking the time to respond. Much appreciated.
Robespierre
5/11/2020 10:34:31 am
China knew at least on March 7, 2020, probably earlier, that RaTG13 and BtCoV/4991 were the same. Why the charade?
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Batwoman
5/11/2020 11:36:33 am
Maybe few in China knew it, but most of the others not. Are you aware that in science you can’t change the name of a sample that it has been published to avoid to lose the track of previous works? Only who has something to hide would do it. Are you a friend of Peter Daszak?
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Sam
5/11/2020 12:45:40 pm
Not at all. I think he has very little credibility and has clearly lied about a number of things, not least his claim to “have no conflicts of interest”! But I am interested in what Nerd makes of 4991.
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Nerd has power
5/12/2020 03:20:10 pm
Hi Sam, here is my take on this 4991.
Dusha
5/11/2020 11:51:09 am
Many thanks for your interesting article! I have one question. You say, "As stated in the [Shi's] paper, RaTG13 was discovered from Yunnan province, China, in 2013." What is the reference for the 2013 date please, as I can't find it anywhere in Shi's 2020 paper here:
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Batwoman
5/11/2020 11:59:32 am
The article where BtCoV4991 is cited is here:
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Nerd has power
5/12/2020 03:32:39 pm
Yes, the publication listed by batwoman is the original one that reported about how this 4991 was discovered back in 2013. Please see my answer right above for my take on this 4991.
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guesswho
5/13/2020 02:34:18 pm
Something more on BtCoV4991. Here https://www.ncbi.nlm.nih.gov/pubmed/26920708
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Aydin
5/11/2020 03:27:28 pm
Interesting to read Peter Daszak@PeterDaszak's tweet:
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Dalstra
5/11/2020 05:25:59 pm
Also add in the fact they have never produced a physical copy of RaTG13 nor let anyone else resequence it’s genome. And the fact that it was not submitted nor published anywhere (Except for the 370bp RaBtCoV/4991) until January 27, well after the outbreak.
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Tongguanzhen
5/12/2020 08:56:58 pm
https://twitter.com/paleovanguard/status/1257416405835792388
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cippi
5/13/2020 02:17:17 pm
TG sounds to me more Total Genome
Aydin
5/11/2020 03:44:01 pm
Per "The Bats Behind the Pandemic" Wall Street Journal by Matt Ridley (4/9/2020)
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John kelleher
5/11/2020 03:46:53 pm
https://connect.biorxiv.org/relate/content/181
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Nerd has power
5/12/2020 03:35:30 pm
I have commented on this article a few times, I believe. Sorry that I won't repeat myself here again, except to say that I'm not completely bought by their evidence and conclusions (although I agree that the virus is of non-natural origin).
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Jane
5/18/2020 06:00:28 am
Can we exclude that Daszak & co. figured out that the spike of BtCoV4991 modified with the RBD of the pangolin CoV and furin site had HIV properties and for this reason they inserted in the BtCoV4991 backbone to develop a super vaccine/drug?
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Nerd has power
5/18/2020 09:39:07 am
Sorry that I don't think I fully understand your question. But I would simply say that 1) I personally have not been convinced that there are HIV sequences inserted into the genome of SARS-CoV-2; 2) no one would try to create a vaccine this way --> making it resemble SARS and then, on top of that, adding a Furin-cleavage site to make it more infectious. The manipulations are intended for the opposite.
Hans Fields
5/11/2020 07:49:46 pm
I ran a sequence alignment on RaTG13 vs Sars-CoV-2 and it only turns up 4 nonsyn mutations on the N protein (419 len). It seems a bit low given that there are 18 nonsyn mutations comparing ZC45 to Sars-Cov-2.
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BreakingBad
5/12/2020 05:06:10 am
China’s own scientists have provided evidence that COVID-19 is man-made
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yano
5/12/2020 06:39:07 am
What is the probability that the SARS-CoV-2 E protein become 100% similar to ZC45 and ZXC21 naturally?
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Nerd has power
5/12/2020 03:43:18 pm
Please scroll back to see the conversation between Anonymous and John F. Signus on this topic. John explained it very well.
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yano
5/12/2020 06:51:11 am
The Feb 11 2020 E protein for SARS-CoV-2 is 100% similar to ZC45 and ZXC21. It is thought that the virus went into humans in Sept-Oct 2019.
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Nerd has power
5/12/2020 03:46:57 pm
You need the size of infected populations to be big enough to see these mutations showing up in sequencing. Please note that not all samples are sequenced. There might be mutations in E from earlier patients, but those may not be selected for sequencing.
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Claire Robinson
5/12/2020 06:53:46 am
An article has been published about Nerd Has Power's research here:
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Nerd has power
5/12/2020 04:05:04 pm
Thank you, Claire and your team, for publishing the article. You have successfully identified me being a male. One error in your article is that you mentioned (twice, I believe) that ZC45 and ZXC21 were discovered by Zhengli Shi. It's not correct. The discovery was made by another lab in China that has a military background. Here is the publication:
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Claire Robinson
5/13/2020 02:14:06 am
Corrected the article--many thanks!
Claire Robinson
5/12/2020 06:55:31 am
An article has been published about Nerd Has Power's research here:
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ioderESTEl
5/12/2020 05:41:15 pm
As if on queue, now that questions about the cleavage site have been raised more widely, Shi has produced another 'natural' bat coronavirus with the requisite cleavage site.
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nonameneeded
5/12/2020 08:14:25 pm
Chinese propaganda in overdrive. I hope no one buys into this nonsense about a new lineage B betacoronavirus with a furin cleavage site that was reportedly collected in May-October 2019 that they sat on until April 2020.
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Lima
5/13/2020 12:19:46 am
It was actually the very old paper on RmYN02. you will need to look at the sequence/alignment more closely.
yano
5/13/2020 10:10:30 pm
What kind of crazy system allows un-verified and possibly fake virus data to be manufactured and uploaded without verification.
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Henri
5/18/2020 03:31:46 pm
Has it not occurred to you that sending live, potentially pathogenic viruses through the post to another lab would be a serious safety risk?
Henri
5/18/2020 01:08:19 am
Are you suggesting that RmYN02 is also a 'fake' sequence?
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Lima
6/18/2020 07:53:32 am
https://drive.google.com/file/d/1gGX4EobrnP3EKYLQDsl9Xa6tKoiwmI8O/view?usp=sharing
yano
5/12/2020 07:42:07 pm
Is this new work with the likely copy and paste 100% E protein and the mysteriously appearing furin cleavage site causing virologists to accept the lab creation theory?
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nonameneeded
5/12/2020 08:16:13 pm
It is not ignorance. It is a conspiracy of silence by virologists who know much, much better.
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nonameneeded
5/12/2020 08:45:25 pm
Edward Holmes is also on the Malayan pangolin coronavirus paper that appeared in Nature.
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John F Signus
5/13/2020 12:22:09 am
See my takedown on it at 5/9/2020 04:13:42 am.
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Dex
5/19/2020 09:54:46 pm
Edward Holmes lab work was outsourced to the PLA.
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Even Yahalom
5/13/2020 11:26:20 am
Who are you?
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Lilian
5/13/2020 02:44:51 pm
I have a question abt the RaTg13 spike protein:
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Lilian
5/13/2020 02:55:26 pm
I just noted that it has 100 % match with SARS Urbani, just after Ratg13
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Lilian
5/13/2020 03:04:09 pm
but missing there the starting ATG...mmh...
Nerd has power
5/23/2020 01:08:10 pm
It may be a conserved sequence at the end of Orf1b. Orf1b and Spike are located right next to each other in the genome, so the end of Orf1b should be right in front of the beginning of the spike.
John F. signus
5/30/2020 08:49:03 am
However, this leader sequence were not found in other SL-CoVs as this in-frame insert. All the other SL-CoVs appeared to have 1 less Nucleotide on the junction meaning that they won’t translate to such.
Physics Guy
5/14/2020 02:23:24 am
Has someone checked the non-synonymous to synonymous ratio of the S2 part of the spike for the mutations that are now naturally occurring in COVID-19? Is there evidence/non-evidence for natural selection in favour of synonymous changes there?
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Libres
5/14/2020 03:20:23 am
Well, the dS/dN on the ORF1ab between RaTG13 and SARS-COV-2 was 6.22:1. Ruling out the possibility that selection in this lineage favoring Syn over Nonsyn.
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Physics Guy
5/14/2020 03:36:38 am
I know, but further evidence as I suggest could further prove/disprove the hypothesis.
nonameneeded
5/14/2020 09:09:16 am
Can you check the dS/dN between specifically GD pangolin vs SARS-CoV-2?for
John F Signus
5/14/2020 03:20:50 am
https://www.sciencedirect.com/science/article/pii/S0092867420302622
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yano
5/14/2020 07:30:52 am
Great! I am so happy people are digging out this information. The world is waiting for justice. Keep up the good work!
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Javier
5/16/2020 09:07:07 am
Congratulations, good work. I'm trying to understand your reasonings, but I have one doubt.
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John F Signus
5/20/2020 05:55:31 am
Well, the hACE2 transfected BHK cells had less affinity to FCS removed S than the FCS on S. BHK itself does not express any ACE2 and is used to model human cells by transfecting it with hACE2 and overexpressing it on the cell surface. the real point is that SARS-CoV-2 fur/mut had the highest affinity to VERO E6 (13500 RLU) than any other assays done. including the SARS-CoV-2 S on hACE2/BHK (13000 RLU).
Nerd has power
5/23/2020 01:33:01 pm
Thank you so much, John. Great finding and analysis!
Bugsy
5/14/2020 06:45:46 am
A two-step approach, first receptor binding, then the addition of a furin site was implied in a study by Ralph Baric's group "SARS-like WIV1-CoV poised for human emergence," replacing the spikes of SARS Urbani and WIV1.
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nonameneeded
5/14/2020 08:39:45 am
For those who are interested, this is the 2014 patent for the chimeric virus construction and serial passaging by Ralph Baric at UNC. The patent was assigned to NIH in 2017.
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Andrew M
5/14/2020 01:01:17 pm
Isn't the differential ratio of synonoymous to non-synonymous mutations simply down to the effect of purifying selection in the region concerened - exactly what you might expect?
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John F Signus
5/14/2020 05:03:38 pm
Well, ZC45 and ZXC21 uses the same host, yet their ds/dn on the S2 was 5:1 with 5 nonsyn mutations. CoV2/RaTG13 have different hosts— we should see both a bigger difference on the S2 and at least a similar dS/dN. However, In RaTG13/CoV2 it was 44:1 with just 2 nonsyn substitutions. Somehow it ended with more nucleotide substitutions than ZC45/ZXC21, yet had less Nonsyn substitutions on the S2 with ZC45/ZXC21. This is completely unnatural.
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Tony
5/15/2020 07:19:04 am
https://www.biorxiv.org/content/10.1101/2020.02.27.969006v1.full.pdf
Physics Guy
5/15/2020 08:20:23 am
As I have suggested above I think it would be good to also look at syn/non-sym ratio of the spike regions in the current mutations of COVID-19. As an outsider to this field to me it seems that this could either further prove the the hypothesis or disprove it.
Andrew M
5/16/2020 01:37:29 am
Sorry, I can't follow this. You just seem to be asserting that different ratios in different places are "unnatural", when in fact it could just reflect stronger selection in certain region(s). The article linked by Tony below seems to this.
Tony
5/16/2020 07:53:45 am
Why there can not be higher “purifying selection” in RaTG13/CoV2 than ZC45/ZXC21?
John F Signus
5/20/2020 05:38:17 am
ZC45/ZXC21 never left the same cave and had the exact same host. There can't be a more stable, purifying selection than this.
John F. Signus
6/18/2020 07:57:05 am
And--unfortunately, CoV2 S2 is not the type of S2 that is under purifying selection. https://drive.google.com/file/d/1Xp1zBf2d-hu32XSKkyJ7UBOg9ZHuAURS/view?usp=sharing
John F Signus
5/14/2020 05:07:08 pm
Sorry, but it keep saying that you does not have the permission to view this page. Could you update it?
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Andrew M
5/14/2020 03:47:27 pm
Another question having read your paper more carefully. You say recombination is rare and thus can't explain differences between the S1 portions of the various coronaviruses. But I have read elsewhere that recombinations are quite common in coronaviruses. The % difference between the genomes and typical mutation rates of such viruses suggest their evolutionary paths 2 diverged decades ago - plenty of time for such recombinations to have taken place. Any thoughts on this?
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Nerd has power
5/19/2020 09:07:40 pm
Sorry for having missed this. I posted something on 5/18 in a reply to charly. You will find my answer to your question there. Please scroll down to read it. Thank you!
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John Kelleher
5/14/2020 07:45:19 pm
I think our governments have no brakes on their train. If the release was planned ,Shi could have published the RaTG13 paper before the release. Maybe ?
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Tony
5/16/2020 08:19:08 am
"nonameneeded the patent you posted seems to be worded to be a vaccine . ,https://patents.google.com/patent/US20170096455"
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Jane
5/18/2020 06:12:46 am
5/15/2020 02:10:17 am
A Nerd has Power.
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John Kelleher
5/15/2020 12:48:49 pm
https://www.youtube.com/watch?v=GUW51MYQ_XQ
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Andrew M
5/16/2020 02:11:47 am
https://www.metabunk.org/threads/debunked-funvax-pentagon-briefing-on-removing-the-god-gene-hoax.317/
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Adam
5/15/2020 08:12:31 pm
I am not a virologist so can't comment on the analysis and its accuracy however why don't you reveal your identity? Are you are based in China and forsee a threat? As you judge others of being biased, would be great if you let the readers judge your biases as well. Not accusing you of anything just making sure we know the person behind the article. I dont understand Chinese hence can't really read the Chinese version.
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Fight Against CCP
5/16/2020 12:26:54 am
I'm not a virologist either. Neither am I the author of this article. However, why do everyone have to disclose their identity especially on internet? Have you ever tried to figure out why and how the world known virologist died suddenly and mysteriously back in this January? Have you ever tried to figure out Czech Senate leader Jaroslav Kubera's sudden death right before his trip to Taiwan? What about the vaccine developer, Liu Bin's being assassinated? I'm sure that you have this common sense as well, as otherwise, you would have disclosed your real full name.
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Nerd has power
5/18/2020 04:38:02 pm
Thank you, my brother. We are in this fight together.
True Crime
5/16/2020 06:56:39 am
Is Shi trying to say now (new paper) that it was not Rhinolophus affinis from Yunnan, but may be Rhinolophus sinicus from... Hubei?
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True Crime
5/16/2020 07:17:54 am
All out:
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5/16/2020 12:40:37 pm
EXCLUSIVE: Virus researchers uncover new evidence implying COVID-19 was created in a lab:
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Lori
5/16/2020 04:11:07 pm
I've been following your work along with reading the comments and just wanted you to know you are not the only one who thinks this virus was manipulated to make it transmissible to humans.
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nonameneeded
5/16/2020 06:51:02 pm
Sad that it's the dailymail that reports on this and not the more "prestigious" mainstream media a la NYT, BBC, Guardian, WaPo. I doubt this will go into a high profile journal, although quite excellent.
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Nerd has power
5/18/2020 01:42:49 pm
Thank you for sharing it. Great article! Reading in between the lines, I can tell that the authors are as convinced as many of us here, and yet they just can't say it in a submitted manuscript. They are so brave to bring their work to the public in this manner. Doesn't matter whether it makes to a top journal, we should spread it.
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Lori
5/16/2020 11:31:11 pm
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Henri
5/18/2020 01:34:14 am
No, it was not 'ordered destroyed' according to the news article. 'The article says 'made substantial changes' which, upon further reading, turns out to be 'remove the terms 'wild life' and 'wild animal'.
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Lilian
5/18/2020 01:41:44 am
You need to practise reading Henri:
Henri
5/18/2020 02:46:58 am
Read the article more carefully, Lilian. Read ALL OF IT. That 'censoring' was not destroying the data base at all. It was changing some words or deleting some words viz: wild animals. Your other points, even if true (which I doubt) does not involve the database.
Lilian
5/18/2020 04:38:49 am
Who is using the word destroying in relation to the database? The article says that the samples were destroyed, not the database.
Ridan
6/18/2020 07:58:36 am
Unfortunately, that 64.3MB database is now gone. completely.
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When asked by Zhong Nanshan if her lab is responsible for creating and losing the virus, Shi says, "She said that's totally ridiculous, she had never been doing anything like that," said Zhong, who called Shi a "good friend."
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CCP is NAZI
5/17/2020 10:05:03 am
How would you expect a CCP criminal to admit their crime? They know exactly what kind of consequence admitting their crime would lead to. None of those CCP's mouths has any credibility including CNN which is short for ChiNiese News who serves as CCP's propaganda. Sadly, none of the sources you use have any professional ethics.
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Henri
5/18/2020 01:10:53 am
What are these 'reliable sources' that the Wuhan lab does not have a hard copy of RaTG13?
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Lilian
5/18/2020 01:18:18 am
Is it not enough that the name of the sample was changed from BtCoV4991 to RaTG13? What do you need more than this demonstration of scientific fraud?
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Henri
5/18/2020 01:41:18 am
This does not answer my question
charly
5/18/2020 03:34:28 am
You can see there https://www.ncbi.nlm.nih.gov/nuccore/MN996532 that they published in 2020 a sequence from a sample collected in 2013. While this does not constitute any fraud, and their claims support it, it is unusual.
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Lilian
5/18/2020 04:31:16 am
It is a fraud to change the name of a sample. In 2016 BtCoV4991, in 2020 RaTG13.
Nerd has power
5/18/2020 02:02:20 pm
This is what I was told by people I trust (hence my reliable sources):
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Henri
5/18/2020 02:49:30 pm
Do, your 'reliable source' is hearsay snd nothing else. You email Zhengli Shi and get a response before you make unfounded allegations
Henro
5/18/2020 03:34:55 pm
So, your 'reliable sources' turns out to be hearsay.
Nerd has power
5/18/2020 04:16:00 pm
You are right. I am the one making the allegation that RaTG13 is fabricated. I wrote a whole article about it. However, this "reliable sources" thing is just a small part of my reasoning. Don't forget there are other more substantial evidence in there. Calling the allegation unfounded is, in my opinion, unfounded.
Henri
5/18/2020 06:06:58 pm
In other words you want someone else to do your dirty work because you din't have the courtesy or courage to do it yourself
Nhele
5/18/2020 09:02:11 pm
How curious Henri that you make such a statement about 'dirty work' and a lack of courtesy and courage. It appears the author of this article has, in a very reasonable way, indicated that he has invited these experts to share their point of view here. Your response sounds childish and repudiates your attempts to present a serious alternative to some very in depth analysis appearing here in the commentary.
Henri
5/18/2020 10:09:00 pm
Nhele,
Leo
5/18/2020 11:38:55 pm
I bet that RaTG13 is not functional. Otherwise someone would have already synthetized it to make a proof of existence using this method:
Justice Defender
5/19/2020 12:03:51 am
The author wrote down his or her analysis, hence s/he is already done with his/her job. Now that you are the one making "unfounded allegations" statement, why cannot you first prove how it is unfounded? If you can show your so called "unfounded"
ll11ll11
5/19/2020 10:19:53 am
I wouldn't argue with this "henri", he apparently just a stupid troll, just ignore him.
Lilian
5/18/2020 01:21:29 am
Synergistic China–US Ecological Research is Essential for Global Emerging Infectious Disease Preparedness
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Lilian
5/18/2020 01:24:32 am
Here you are:
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charly
5/18/2020 03:44:53 am
Some red flags triggered during my reading:
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Nerd has power
5/18/2020 03:27:46 pm
Thank you for the comments. I was just about to call the day for blogging and move on to other things. Your red flags gave me a reason to linger here a bit longer. I will address each of the points you raised.
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John
5/19/2020 07:04:06 pm
People win the lottery sometime too, Covid likely a gain of function experiment but not impossible that is came from wet market. On the other hand, how many doctors get reprimanded for using WeChat for simply noticing a SARs like infection in the hospital and sharing it with other Docs in Wuhan. No real reason to "kill the messenger" over a natural spillover event unless they are covering something up.
Nerd has power
5/23/2020 02:08:11 pm
Yes, you are right in that they can always argue that, even if the chance is one out of one million years, it is still a possibility. That's the beauty of recombination.
Shannon Entropy
5/20/2020 07:44:36 pm
I tried to do my own mathematical analysis of the Wuhan virus genome compared to the other known beta corona viruses. I was able to download all the genome data from www.viprbrc.org.
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Verner Von Rovan
5/21/2020 06:42:22 am
RmYN02 actually had two deletions. one at T678 and the other at S686. the nt sequence appears to possess multiple short indels scattered across the S1-S2 junction when compared against ZC45. a hallmark of an low-quality sequence being used for assembly and resuled in a misplaced contig at S1-S2.
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Henri
5/21/2020 09:41:29 pm
If what you say is correct, then why not send a letter to the Editor of Cell and see if you get a response? They should pass you letter on to the authors and allow them to reply followed by publication of both letters at the same time.
yano
5/22/2020 07:54:46 am
https://www.biorxiv.org/content/10.1101/2020.05.01.073262v1.full.pdf
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Andrew M
5/22/2020 11:26:06 am
You appear to be reading something in this article which isn't in it. Search this discussion thread for "Bill Gallagher". Read that. Go to his site and read the rest of his comments. There is nothing about the S protein which implies a man-made creation.
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yano
5/22/2020 12:14:41 pm
I understand I am reading something into this article. This is why I am asking for input.
Tony
5/23/2020 10:25:28 am
You mean Bill Gallaher(?):
Nerd has power
5/23/2020 02:35:49 pm
Thank you, Yano, for bringing up this preprint article again (someone did it in an earlier comment too). It is THE best work so far, in my opinion. Very powerful analysis. The pattern is not just seen in the S protein. It's the overall feature of adaptation: SARS-CoV-2 is well adapted to humans from the very beginning, while SARS clearly worked diligently in the earlier stages to gradually settle down in the human population. In other words, SARS did look like a virus jumping from an intermediate host to humans. SARS-CoV-2 did not.
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Med
5/22/2020 11:29:53 am
Hi,
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Andrew M
5/22/2020 12:33:34 pm
The Epoch Times is Falun Gong propaganda. They have less interest in science and more in discrediting the CCP. Their motives may well be good ones - I make no comment on that. But the HIV insertion story is nonsense - it has been thoroughly debunked and is not worth pursuing. It detracts from Nerd's theory, which is at least worth parsing,
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Shakti
5/22/2020 12:52:21 pm
You have presented a lot of very interesting information here but I don't understand one thing - why is everyone referring to Dr. Shi Zhengli as Dr. Zhengli Shi? I'm pretty sure that Shi is her first name.
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mz1-2-3-4
5/22/2020 03:38:50 pm
You are simply clueless in this very topic (the name). Her name: Last = Shi; First = Zhengli. In Chinese: 石正丽
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Shakti
5/22/2020 03:51:46 pm
My sincere apologies for the mistake. I only read articles in my native language, English, where she is always referred to as Dr. Shi Zhengli - and in English, the name that comes first is the first name.
Andrew2
5/22/2020 02:44:37 pm
I think This is HIV insertion paper...Please discuss it after reading not before reading!
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Andrew M
5/22/2020 03:41:31 pm
I can't say I understand this paper - particularly when I got to the part about the golden ratio numbers in DNA. The 2 authors really do not check out very well. Montagnier, true is a Nobel prize winner who made excellent discoveries in the past but is now an 87 year old embracing some quack homeopathy "science" theory and the other guy - well - read his Twitter.
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Annette
5/23/2020 01:13:51 am
I found Montagnier paper very informative and robust. My understanding is he was able to detect electromagnetic signals at high dilutions and is quoted as saying "High dilutions of something are not nothing. They are water structures which mimic the original molecules.” A Homeopathy uses high dilutions the proof that remedies have an effect when prescribed professionally should not be debunked but further understood. It is a poor scientists who closes his mind to research as it will limit his/her ability to see things outside of the expected.
Andrew2
5/22/2020 04:15:54 pm
I am sure there is something there as original sars was also had similarity with HIV...also some of the signs of this disease are similar to aids but no one compare those! I am especially worried for long term chronic form of disease with some kind of immunodeficiency for life ..also a paper shows the same genetic risk factor for HIV, could influence your resistance to covid, please see PMID= 23361009 ...I really hope I am wrong!
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Andrew M
5/22/2020 04:39:30 pm
There isn't "similarity" - they are completely different viruses. They have different proteins doing different things (with some overlap, admittedly). This paper seems to find repeated short sequences, after searching through all HIV genomes available (there are quite a few!). Before we even get to considering why viruses and their proteins might have common short sequences for natural reasons, where is the statistical analysis to demonstrate this is anything other than random?
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Andrew2
5/22/2020 04:52:51 pm
I know but those sequences are unique to this virus...don't forget francis Boyle that for many years claim all SARS are man made!
Andrew2
5/22/2020 04:48:48 pm
oops...that was older paper...The pmid=32348495. In that paper please check ref10.
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Andrew2
5/22/2020 07:36:32 pm
Ref8
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Greg
5/22/2020 11:58:41 pm
Hello, I found your blog post very interesting but I have one question regarding the dn/ds ratio that you use as evidence to show that either ratg13 or sars-cov-2 is not natural. First, isn't it a more parsimonious explanation that the skewed dn/ds ratio in certain portions of the S protein gene is due to the fact that cov-2 contains sequences from the pangolin derived coronavirus, specifically in the RBD region of the S protein gene and therefore in those regions, the dn/ds ratio would be different compared to the rest of the genome? Shouldn't one compare the dn/ds ratio in the RBD region of cov-2 to the RBD region of the pangolin derived virus? Also, even if they are different, a skeptic could say so what. Although this may not occur often, it could occur just due to random chance. Is there any way to test whether the differences are statistically significant using a Chi square test or something like that?
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Nerd has power
5/23/2020 02:19:28 pm
Thanks for the comment. The RBD is in S1, not S2. So the comparison of dn/ds for S2 is not affected by a possible RBD-specific recombination.
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Greg
5/24/2020 06:51:50 pm
Thanks for your response. But what about the fact that positive or negative selection can also skew the dn/ds ratio? Couldn't a skeptic just say that the S2 region underwent strong positive selection, accounting for a high dn/ds ratio, while the rest of the genome is under negative or purifying selection which produces a low dn/ds ratio? This alternative explanation could account for the genetic peculiarities of Cov-2, but it seems like it would raise more questions, specifically it seems like cov-2 is well adapted to humans, its genetic polymorphism resembling the original SARS virus late into the epidemic after human adaptation. The question then becomes in what host this adaptation (positive and negative selection) occurred. It wasn't pangolins and it wasn't bats since the binding affinity of the S protein to human ACE-2 receptors is greater than to the bat/pangolin ACE-2 receptor. There's also no evidence of early adaptation of Cov-2 to a human population. Isn't the most likely explanation that Cov-2 adapted to human cell culture lines?
John F Signus
5/25/2020 10:40:53 am
Even the pangolin strain had 8 sense mutations on the S2. The virus itself is about 10% different and the mutations on the S2 appears to have been saturated. However, with the ZC45/ZXC21 bearing 5 dN at a level of similarity being ~97% and pangolin/CoV2 bearing 8dN at a level of similarity being ~90%, the ~96% similar RaTG13/CoV2 can never have just 2dN. The expected dN should be between 5 and 8– and the pangolin strain tells that the dN on RaTG13/CoV2 is far from saturated. The 44-to-1 ratio should never happen at all.
John F Signus
5/25/2020 10:42:33 am
John F Signus
5/25/2020 04:13:59 pm
The tens of million refers to all sequencing reads.
Greg
5/25/2020 10:22:38 pm
John F Signus, that’s quite an explosive claim. You are saying that the pangolin lung tissue has up to 40 percent human DNA? It would be easy to test whether this came from a cell culture or whether it was a contaminant, if it was a contaminant it should’ve been from human rna from skin epithelial cells, ie basal cells in the skin or something like that. If it’s a cell culture, there should be a particular rna that’s more likely to be expressed in human cell lines
John F. Sugnus
5/26/2020 08:52:08 am
Exact RNA type may not be known or important--there are hundreds of different cell culture lines, many of hich were used to culture viruses within. also, we do not know how the samples were contaminated, other than the fact that it can only happen after the sample have been taken and that it formed significant mass fractions in all samples with reads positive for the "pangolin coronavirus". with samples that tested negative showing no such contamination.
John F. Signus
5/26/2020 08:57:11 am
Lung09 is nearly 65% hominid DNA in total-- and judging by mass of the sample (Human DNA/pangolin DNA), the actual mass fraction directly attributed to humans is more than 69% the total weight of the sample--and they do say that some of the S reads were mapped there......Very likely thatthe RBD was one of the previous GOF experimental cultures being mixed up with the actual sample.
Nerd has power
5/26/2020 09:14:13 pm
That is fantastic, John. Thank you for sharing it with us. Have you seen this preprint article?
John F. Signus
5/27/2020 05:46:54 am
On the Dataset SRR10168374, or Lung12. This dataset was claimed by the third article to contain Coronavirus-related reads. however Genomic analysis on the NCBI database failed to identify any.
Nerd has power
5/27/2020 06:17:52 am
Thank you so much, John. I have to read it a few more times to better understand it as I'm no expert in such research. But from what I can understand so far, it's already rock solid. Amazing work!
Nerd has power
5/27/2020 06:22:17 am
Judging from the quality of the figure, I can see a publication coming out of this, which would be amazing. Thanks again for revealing this truth! I look forward to the published article!
John F. Signus
5/27/2020 06:34:18 am
17% human by sequence and 26.1% human by total sample mass--Indicating a heavy contamination by SARS-CoV-2 containing COVID-19 test material. The strange dataset was heavily redacted and contained no other non-coronavirus-related reads making analysis of contamination difficult. However, the sequencing date was after the Outbreak and are very close to the Nature article sequencing date, meaning that it was likely a workbench version of the "pooled reads" from the method section of the early Nature article, which have sequenced a contaminated sample that returned the same two signals with a total mass fraction being 26.1% human, so far remaining the only unabridged dataset that had these two hits.
Rubber Ducky
5/23/2020 04:14:21 am
Synonymous mutations and the molecular evolution of SARS-Cov-2 origins https://doi.org/10.1101/2020.04.20.052019
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Johnny M
5/23/2020 05:33:02 pm
1. CoVID-19 symptoms relates to Nipah Virus - it has massive cell-to-cell fusion and primarily relates to endothelial cells.
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yano
5/25/2020 02:27:48 pm
https://arxiv.org/abs/2005.06199
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CCP is NAZI
5/25/2020 04:52:02 pm
Australian scholars reveal that CCP virus is carefully lab engineered and optimized to infect human:
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Alesh Aras
5/25/2020 05:22:34 pm
How will the below change your conclusions?
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Mr. Tuesday
5/25/2020 10:23:37 pm
https://www.biorxiv.org/content/10.1101/2020.02.15.950568v1.full
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John F Signus
5/26/2020 08:38:29 am
Did you just say "unique synomynous codon usage" on the S protein? it would be exactly what is expected for a synthetically constructed protein being back-translated to a nucleotide sequence, with a bunch of synomynous mutations thrown in to make it more "distinct" from known nucleotide libraries. they failed to account for the codon usage, though.
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Nerd has power
5/26/2020 09:27:43 pm
I know it's hard for any author in a submitted manuscript to call it out, but really our claim here works perfectly in interpreting their finding that "SARS-CoV-2 and RaTG13 might have undergone different evolution pathways". It is this way because at least one of them is not natural. I will have to study their paper more, but can't help comment on it first.
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Mother Jones
5/26/2020 10:40:00 am
https://link.springer.com/article/10.1186/s12985-017-0766-9
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Nerd has power
5/26/2020 09:47:03 pm
Thanks for sharing. Yuri first found out about this and posted it on Twitter. It's an alpha coronavirus that is far away from SARS-CoV-2 or beta coronavirus in general in terms of sequence identity. Therefore, RRAR in SARS-CoV-2 could not be acquired through recombination.between a precursor beta coronavirus and this alpha Coronavirus.
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Henri
5/27/2020 02:58:26 am
I have asked you this before and got no reply. I'll ask again. Why don't you write up your hypothesis that RaTG13 is fake, based on your analyses presented in this blog, and submit a letter to the Editor of Nature Medicine? The Editor should pass the letter to Zhengli Shi and allow a reply. Then, the two letters might be published together in a future issue of nature Medicine.
Nerd has power
5/27/2020 05:38:19 am
Thanks, Henri. I appreciate your suggestion. Challenging Shi and RaTG13 in a reputable journal would be a powerful approach. However, these journals may not be as accommodating for "conspiracy theorists" as people wish. If you looked back on some earlier comments, you will see how Nature has refused to publish an article written by a reputable scientist, arguing for a lab origin of SARS-CoV-2. My attempt would not turn out any better. On top of that, I prefer to not reveal my identity as many do here. Things might change, who knows. If you can't wait, please check out the link below. Some people have already published preprint manuscripts challenging the authenticity of RaTG13:
Henri
5/27/2020 07:42:31 pm
Nerd has power
5/29/2020 04:14:09 am
Thank you very much, Henri. That's a wonderful proposal. It would be great if you could send a letter to Nature Medicine, drawing their attention to my blog. I would be more than happy to edit your letter. When you post the letter, please use a fresh comment as it gets hard to roll back and check old comments.
Uncle Weatherby
5/26/2020 10:01:07 pm
China Rules Out Animal Market and Lab as Coronavirus Origin
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CCP is Nazi
5/26/2020 10:11:07 pm
Who gives it a damn shit on what China has to say? What did they say that is not a lie? Isn't WSJ bought by CCP as CCP's mouthpiece? Which NAZI criminal would admit their NAZI conduct?
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Alesh Aras
5/26/2020 11:01:13 pm
I would rule out wet market as well: China in a hurry to reopen wet markets is prima facie evidence that the CCP doesn’t think that the virus came from there.
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CCP is NAZI
5/26/2020 11:12:54 pm
But CCP rules out their P4 lab as the CCP virus origin as well. It's like saying this shit is not from their ass but from someone else'. Once I see the subject in the URL, I would not even waste a single second to read on.
Alesh Aras
5/26/2020 10:59:20 pm
Bat woman Shi Zhengli has resurfaced.
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Nerd has power
5/27/2020 05:55:49 am
The head of the Wuhan Institute of Virology also gave an interview:
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Tony Soprano
5/27/2020 09:12:04 pm
The Wuhan Seafood Market theory of the origin of SARS-CoV-2 is out and the "multiple origins" theory is in.
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CCP is NAZI
5/27/2020 10:15:30 pm
Who gives it a damn shit on what China has to say? Ya, Nature with a bunch of Chinese "scientists" who only speak what their NAZI CCP want them to say. Otherwise, the lab in Shanghai would not have been ordered to shut down shortly after the lab shared the virus sequence. But are you sure Nature is still science centric and not bought by CCP if CCP have already bought bigger organization like WHO, WTO and many other world organizations? I am so glad that President Trump stopped funding WHO. Let's see how many lies WHO continue to tell the world without the world's biggest donar.
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Leo
5/27/2020 11:11:26 pm
The journal Nature is corrupted, they have so many connections with EcoHealth Alliance.
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CCP is NAZI
5/27/2020 11:26:17 pm
Have you actually compared its sequence with CCP Virus' sequence side by side? If so, why don't you bring its sequence here to let virus specialists verify? Even look at it from a non scientific perspective view, with such a high infectious rate that CCP virus has, why nothing happened in U.S. afterwards until after Wuhan lock down? Interestingly, CCP tried their very best to help this deadly CCP virus spread as fast and wide as possible all over the world by silencing 8 doctors like Li Wenliang , by destroying all virus samples, by stressing it's preventable and controllable, by denying the fact about human to human transmission, by letting people out from Wuhan to everywhere in the world but not within China? Were CCP able to prevent and control it? Exactly, what's CCP's hidden agenda? Well, aren't these https://www.newsmax.com/navrozov/china-biological-russia/2009/09/17/id/335042/ and https://www.theepochtimes.com/did-chinas-plan-to-destroy-the-united-states-backfire_3223117.html enough to tell CCP's world domination goal?
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Leo
5/28/2020 12:35:24 am
We need a forensic analysis on these early cases in USA.
CCP is NAZI
5/28/2020 06:38:24 am
I know everything including how NAZI CCP have been faking their total sum of infected cases, how Obama administration used their tax payers' money to fund HIN who then outsourced to Wuhan P4 lab, how CCP have been threatening each country and scientist who is revealing the truth and facts, how CCP have been developing biowar non stop with still tons of under developed virus in their P4 lab which are far more lethal than what was already released, the so called CCP virus, how CCP have been destroying the virus samples, how CCP have been shirking their crime, how https://nextstrain.org/ncov/global shows all CCP virus mutation could be traced back to China. Oh, too much to list.
Bubba Gump
5/28/2020 12:31:29 am
This article "Viral and host factors related to the clinical outcome of COVID-19" https://www.nature.com/articles/s41586-020-2355-0, published on May 20th, which is now being used by China and the media as the basis for the "multiple origins" theory for SARS-CoV-2, appears to suffer from many of the same problems as "On the origin and continuing evolution of SARS-CoV-2" https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwaa036/5775463, published in March 2020, as explained in a criticism of it http://virological.org/t/response-to-on-the-origin-and-continuing-evolution-of-sars-cov-2/418
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CCP is NAZI
5/28/2020 06:45:19 am
At this moment, the most important is not who has published what considering how many world organizations and journals CCP have been buying, threatening and silencing(Isn't WHO the best example to prove my point?) but when CCP can open their Wuhan P4 lab.
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Leo
5/28/2020 07:02:16 am
I am not sure if USA has the most accurate testing for covid19 cases:
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Leo
5/28/2020 07:04:52 am
This article is quite good for an overview of the facts
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Leo
5/28/2020 07:20:32 am
This is also interesting:
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CCP is NAZI
5/28/2020 07:32:53 am
I'm sorry, but I don't waste even a single second on CCP propaganda such as global times, cnn, nytimes. Trump should craft executive order on fake news just like how he crafts one for social media. I cannot wait to see how 50 cent army will suffer from this: https://www.foxnews.com/politics/trump-crafts-executive-order-on-social-media-weighs-commission-to-probe-bias-amid-twitter-fight I will be eager to test out if anti CCP words still keep disappearing on YouTube and will definitely sue them once the order comes to legal effect.
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Leo
5/28/2020 07:47:12 am
It is probably hard for CCP to open their lab as it is for Fort Dietrich.
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Bubba Gump
5/28/2020 07:53:02 am
Can we stick to scientific analysis here? Political diatribes contribute nothing to what we are trying to achieve.
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Leo
5/28/2020 08:02:52 am
You are right, but it is difficult to avoid to make the discussion political. If this virus is lab made, it is normal to try to find out from which lab it might come. We probably need to wait for more analysis like the one done by Forster with more data.
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charles
5/28/2020 10:31:50 am
Stop sidetrack the discussion. You are just trying to throw in multi-origin conspiracy theories to deflect the spot light on CCP - a typical CCP propaganda and a trick by the Global Times shills. The quickest and easiest way is always transparency from CCP. They are stonewalling from day 1 and their further actions to destroy evidences speak loudly of their complicity in their role in the pandemic to say the least.
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Nancy
5/28/2020 11:02:40 am
You're absolutely right, charles! 50 cent army is everywhere. Luckily, this site isn't paid or operated by CCP. Otherwise, the truth and facts discussed here would be censored or deleted just like YouTube /Twitter/Facebook. There isn't anything easier than being transparent or opening CCP's P4 lab to prove if CCP are NAZI criminals or not. Unfortunately, Xi Jinping suggested to open their lab to the world in a year, after all evidence are destroyed or everyone forgets about it. Come on, no one would ever forget this NAZI crime! If we let it go this time, we don't even know how we die tomorrow!
Bubba Gump
5/28/2020 11:26:00 am
I recommend that the administrator delete the childish political comments before they ruin the site. The children can go waste people's time ranting on Twitter or elsewhere and let the adults have a serious discussion about the science here.
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Nancy
5/28/2020 01:21:27 pm
Which adults fist started the political games here? Which adults only talked about who says what, but nothing substantial or scientific from
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CCP is NAZI
5/28/2020 12:20:17 pm
I also request the administrator to remove CCP's "multiple origins" conspiracy theories along with CCP propaganda to clean up the trash and lies. Just bring your own analysis, virus sequence and facts here.
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Bubba Gump
5/28/2020 08:08:35 pm
Here's the problem in a nutshell - when you have people like "CCP is Nazi," who pollute a scientific discussion with useless political comments, it ruins the site. "CCP is Nazi" either did not read or did not understand the articles about "multiple origins" upon which my post was based. The last citation is a scientific criticism of the articles supporting "multiple origins." So, my post about "multiple origins" debunks rather than supports the theory of "multiple origins." Not surprisingly, "CCP is Nazi" got it all wrong, is the one who is the distraction, adding nothing to the scientific discussion and will end up ruining it for everyone. Sadly, that type of behavior is all too common on social media sites, people with big mouths and little brains.
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CCP is NAZI
5/28/2020 09:56:47 pm
This is not the first time I name like this. I don't know why you are the only one fussing about this. Anyone can decide what name to use just like how you name yourself as Bubba Gump instead of your
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Bubba Gump
5/28/2020 10:23:05 pm
The irony is people like "CCP is Nazi" and "Nancy" practice exactly what thw communists and Nazis did, that is, the political interpretation/use of science e.g. Soviet Lysenkoism and Nazi racial science. Offer scientific analysis here and reserve your political views to a more appropriate forum.
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CCP is NAZI
5/28/2020 10:42:01 pm
While Bubba Gump is asking others not to talk about politics, he himself is just doing the same. How funny! Those who do not agree with CCP is NAZI are undoubtedly NAZI themselves.
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Rose
5/28/2020 11:21:45 pm
I suggest to use rather our energy to definitely demonstrate that SARS-CoV-2 is lab made, in a way that it is finally accepted from the rest of the people who still think is natural, because I fear they are still the majority.
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Bubba Gump
5/29/2020 03:07:47 am
"Rose," Peter Daszak started his career in parasitology and migrated into virology. Here is a review article he published in January 2000 with some of his citations. He was into Nipah virus before coronavirus, I believe.
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Rose
5/29/2020 03:46:44 am
Ah yes thanks, it is the same article I posted. I am just wondering if he could have seen before emerging of SARS, that bats carried CoVs, since he was already studying their viruses before 2000.
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Nerd has power
5/29/2020 04:50:06 am
I appreciate everyone's contributions to this comments section. It has certainly surpassed my exceptions. Many analysis and findings that people shared here are just brilliant. We are piercing deep into the thickness. It's great.
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Henri
5/30/2020 04:42:22 am
I have composed a 'diplomatic' letter for Nature Medicine. The technical bit, which I need you to check over and correct if necessary is below.
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Henri
5/30/2020 07:26:24 pm
The letter to nature is ready to be submitted. Please check the technical bit given above and make any changes you feel necessary. If I don't hear from you soon, I shall submit on the assumption I have described your main objections correctly.
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Lilian
5/29/2020 06:09:28 am
I have found some interesting information on the ORF10 in SARS-CoV-2
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Jule
5/29/2020 09:47:41 am
What I do not understand is why Shi did not simply synthesize RaTG13 to avoid any suspicion.
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Rose
5/29/2020 10:31:21 pm
I bet that RaTG13 is not functional as designed. Let’s see if someone try to synthetize it.
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Tim Pearson
5/29/2020 12:51:36 pm
When the SIV of sooty mangabees crossed over into humans and became HIV, there weren't any alternative theories that some local laboratory within West Africa had been responsible for that occurring.
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Rose
5/29/2020 10:34:47 pm
You can ask Fauci, he is the HIV expert and best friend of Daszak
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ioderESTEl
5/29/2020 03:00:16 pm
So SARS-CoV-2 has another dangerous characteristic tied to ORF8. I wonder if another animal virus sample showing this particular characteristic will suddenly be published.
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Rose
5/29/2020 10:18:32 pm
You can have a look here:
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Reminder
6/8/2020 07:16:05 am
If the link is down, here is a mirror to that file.
Pete Ross
5/30/2020 05:56:29 am
To add or subtract from the mystery of SARS-2 (CoV2) origins are this series of tweets from Dr. Peter Daszak of EcoHealth Alliance, recently deprived of NIH funding just last month.
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Alexandrian LC rocks
5/30/2020 09:11:06 am
This is an important lead. Remember Shi’s previous statement? They were gathering bits and pieces from naturally occurring viruses throughout the world, mix and match them in the lab not necessarily with seamless ligation, put them throughout cell and animal passage Until they generated the perfect disease X to be unleashed into humans. All in the name of “saving wildlife”.
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pangolin
5/30/2020 10:44:17 am
I perfectly agree with disease X possibly being SARS-CoV-2 but the market has nothing to do with the initial spread. The real boosters were the military games in Wuhan in October 2019. There are posts here on it.
Alexanderian TD Rocks
5/30/2020 09:13:24 am
From an early source. Explain the EcoHealth agenda very clearly.
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Babstar
5/30/2020 01:04:39 pm
Alina Chan just tweeted ?
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Henri
6/1/2020 07:47:19 pm
Why does the noose tighten? No one denies such reearch has been performed.
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George Formby
5/30/2020 10:48:01 pm
This first appeared as a pre-print at the end of March, published on May 29th.
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Nerd has power
6/2/2020 06:15:44 am
Thank you for bringing up this paper. I think their evidence proves the opposite. They mainly argued that because all the suspicious elements of SARS-CoV-2 (RBM, furin-cleavage site) are hinted to exist in nature, then recombination must be responsible for the appearance of SARS-CoV-2. Of course, in my eyes, they used all the wrong sequences, RaTG13, pangolin coronaviruses, YN302, to do their analysis and thus support their "conclusion". But I think their data revealed the opposite. When they analyzed the syn/non-syn mutations, they showed extreme high purifying pressure for SARS-CoV-2, RaTG13, pangolin viruses in S gene and in other genes (figure 4 and 5). Unfortunately, they did not always include a similar analysis of another group. I think they probably did those analysis in figure 5 and I suspect that the results are too daunting and not aligned with their "conclusion" of natural recombination being the source. I will try to find the time to do that comparison for them.
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John F. Signus.
6/8/2020 07:06:18 am
Also, Here is a complete, detailed analysis on why RmYN02 itself--Not only it have no furin site, but it was also Not viable!
Javier
6/2/2020 12:59:54 pm
ZXC21 and ZC45 : strong purifying selection and same habitat (in caves collected by a military research lab of the CCP)
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Henri
5/31/2020 06:09:21 pm
Open request to NerdHasPower:
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yano
5/31/2020 09:16:52 pm
E) At the beginning of the 2019 pandemic SARS-CoV-2 was better adapted to infect humans than any other animal. No selective mutations or adaption to humans was needed (or observed). This suggests the virus was already well adapted to human cells and did not come from animals
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Henri
6/1/2020 03:41:43 am
Letter submitted. Let's see what happens.
Nerd has power
6/2/2020 05:08:10 am
Sorry for not responding earlier. Did not find the time to pay a visit here for two days. You were saying that you needed 1 or 2 weeks to draft the letter. So I didn't think you have it ready already. Anyways, the letter looks very good to me. Point C did not explicitly state that comparison was done for the Spike, but that does not hurt the argument or make anything incorrect. Thanks again for doing it. Please keep us posted with the results.
John F. Signus
6/8/2020 06:59:41 am
Also YNLF31C/SARS.
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MagmaHombre999
6/2/2020 12:40:07 am
Have you considered the possibility that rather than the changes in the ratios of synchronous to non-synchronous mutations were in the published "RaTG13" genome were an intentional signal from Dr. Shi as she was probably ordered to conduct the cover-up??? Could there be a coded message in the changes???
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Nerd has power
6/2/2020 06:59:36 am
I don't know, but I do hope that's the case. If one day she would be able to come out and tell the truth to the public, it would be good for the world and for herself. Maybe she desires for such an opportunity too.
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Henri
6/2/2020 07:20:09 pm
The Letter to Nature was rejected outright. I appealed. The appeal failed. I now intend to take the matter up with the Editor-in-Chief. If that fails to get the letter published, we must discuss our next move.
Henri
6/4/2020 03:32:54 am
Radio silence form the Editor in chief and Nature. So, NerdHasPower, where we do we go from here? I have a couple of ideas. Your thoughts please.
Lilian
6/2/2020 10:41:35 am
The Case Is Building That COVID-19 Had a Lab Origin
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Javier
6/2/2020 12:42:37 pm
Three well done summaries, reported by Claire Robinson
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6/3/2020 08:33:59 am
Hello Nerd,
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Henri
6/3/2020 07:20:51 pm
You seem to have misunderstood my position. I am on the side of 'it was NOT made in a lab'. NerdHasPower has put forward SOME arguments that RaTG13 is fake. As a scientist, I believe his arguments summarised in my letter require addressing by the Wuhan group. I believe there are satisfactory answers in scientific terms.
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Robert Cartwright
6/4/2020 02:17:44 am
Here the new paper of Perez and Montagnier 6/4/2020 02:42:14 am
Sorry, I meant to address the blog owner and the author of the original post.
Robert Cartwright
6/4/2020 02:42:39 am
I think Henri's comment about Montagnier and Perez is exactly the same as that of the mainstream scientific community: many, many organisms came up with the same short HIV sequences. This, in my opinion, completely misses the point. The problem is not that the sequences are short and common but where they are located, and what mutations it induces subsequently (i.e. the S1 protein). This, I seem to understand, has been deduced by artificial intelligence simulations and, contrary to what Henri thinks, is the most sensible research direction to explore. This hypothesis, in the absence of information from Wuhan) is a hypothesis that can be verified ex-post only by analyzing whether the evolution of the virus deletes the exogenous RNA Sequences. The new Perez and Montagnier show that this is happening
Nerd has power
6/4/2020 09:52:09 pm
Thank you, Lila, for the comment and thoughts. I have answered the question of whether or not HIV sequences have being inserted into the SARS-CoV-2 genome. But I understand that it is very hard to screen all the comments now. My short answer is that I'm not convinced that such insertions are true. Or I should say that my own analysis failed to convince me in believing so. My conclusion that the virus is man-made is apparently based on other evidence and reasoning.
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Greg Felton
8/21/2020 02:02:45 pm
Hi Nerd:
Lilian
6/3/2020 03:12:53 pm
Another article worth to read
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Wilson Volleyball
6/4/2020 01:06:12 am
Exclusive: Coronavirus began 'as an accident' in Chinese lab, says former MI6 boss
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Andrew M
6/4/2020 03:41:02 am
Some of the commenters don't leave facility for a direct reply - I don't know why that is. So, a general post about HIV, Montagnier and Perez. And Dearlove.
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Henri
6/4/2020 03:56:25 am
I agree. That is why in my letter to Nature I have mentioned only what I feel are the most powerful points made by NerdHasPower. I still have faith that there is a satisfactory explanation. But, I also feel Nature has a public duty to investigate the claims. They have remained stubborn about not publishing the letter. No real reason given. So, what next? Any suggestions?
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pangolin
6/4/2020 03:59:35 am
I would try to find another journal not controlled by EcoHealth Alliance. But it might be hard.
Andrew M
6/4/2020 06:17:01 am
Write it up formally as a paper and find a journal willing to publish it as a pre-print, inviting peer review?
Robert Cartwright
6/4/2020 04:16:18 am
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Andrew M
6/4/2020 06:04:07 am
"I don't think Andrew M read Perez and Montagnier's latest article"
Henri
6/4/2020 04:11:35 am
Possibly. But, it was Nature who published the RaTG13, so Nature should answer.
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pangolin
6/4/2020 04:30:15 am
Nature even did not add yet the information that RaTG13 is BatCoV4991 on their paper:
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Henri
6/4/2020 04:58:17 am
Hallo NerdHasPower,
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yano
6/4/2020 08:06:56 am
So typical of cancel culture. When an opinion turns into fact science tat cannot be challenged.These so called experts are a joke.
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Hcnri
6/4/2020 09:28:29 am
No, it is not published
Nerd has power
6/4/2020 09:12:32 pm
Thanks, Henri, for your great effort. I wasn't surprised with the way Nature responded -- I think people have said in an earlier post how Nature has turned down an article with a similar argument. I don't really have any suggestions in terms of how to make Nature change its mind. It is already very hard if it's a less sensitive topic.
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Henri
6/4/2020 10:43:06 pm
I am toying with the idea of getting the UK press involved. What do you think?
Eva Celia
6/5/2020 02:23:54 pm
Do you read that a professor did a study and already said that this virus is natural?
evidence
6/4/2020 01:04:11 pm
Today came out a quite good up-to date review by Milton Leitenberg
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Henri
6/4/2020 07:46:33 pm
1) The WIV is an Academic Institute. The research groups will consist of Group Leaders, Clinicians, Senior Scientists, Post-Docs, Ph.D students, undergraduates and International collaborators - all from academia, not military. Are you suggesting that somewhere among these there was a secret group working on a bioweapon withou anyone else in the lab knowing about some kind of secret research?
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Nerd has power
6/4/2020 09:36:34 pm
Thank you, Evidence, for the comment and insights.
Dex
6/4/2020 10:06:59 pm
This kind of research may have dual purposes. Clearly the US Department of Defense has an interest in it, evidenced by their extensive funding of EcoHealth. The stated interest maybe purely to develop defensive capability (i.e. a vaccine in case of a terrorist bioweapon attack is the scenario commonly cited, and most funding came from a Threat Reduction agency).
evidence
6/6/2020 07:56:19 am
@ Henri. Thanks for your questions.
evidence
6/6/2020 08:10:17 am
Javier
6/10/2020 02:36:25 pm
There is no scientific 100% evidences at all.
Javier
6/10/2020 02:29:17 pm
When I start reading an article and the first or second paragraph of the article started talking about Trump, Pompeo...
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Jagdish
6/5/2020 09:53:39 pm
Preprint questioning origins of RaTG13 and highlighting serious concerns on the methodology of genome sequencing used by Zhengli Shi et Al came out yesterday.
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Henri
6/5/2020 11:36:46 pm
RE:
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map
6/6/2020 05:12:04 pm
Your arguments seem to me to suggest that RaTG13 was only sequenced very recently. If that is the case, then why does not Shi have a sample of the virus ?
Henri
6/6/2020 06:57:29 pm
'Map:
Nerd has power
6/7/2020 03:33:08 pm
Henri, I think you are contradicting yourself here. If you agree that 4991 is RaTG13 and was found in 2013, then your own point #1 is gone. Shi has admitted to people that 4991 is RaTG13. So yes, she did sit on it for SEVEN years.
John F. Signus
7/22/2020 10:01:25 pm
https://drive.google.com/file/d/1vTV2d7SqHcsLB0R-QwY0Ua8fec5A_fk4/view?usp=drivesdk
Javier
6/6/2020 06:09:38 am
Dr Sean Lin in https://www.youtube.com/watch?v=XO_kvtrfPWc
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Henri
6/6/2020 06:14:11 am
In an interview, the lab head mentions that all the sample has been used up. If you are a lab researcher, you will know that samples eventually get used up.
Javier
6/6/2020 12:20:52 pm
It seems there is still a claim for raw data and related RaTG13 samples??
Javier
6/7/2020 02:08:38 am
Hi Henry,
John F. Signus
6/8/2020 06:56:30 am
I don't think RaTG13 was from a "fecal swab".
Greg
6/6/2020 04:04:08 am
The way I see it is that some of these claims are testable, others provide some evidence of manipulation (but no smoking gun), while other simply don’t stand up to scrutiny:
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map
6/6/2020 05:49:26 pm
Regarding A) I don't think that RaTG13 being able to infect horseshoe bats would discount it as being fake. It think it would be quite possible to invent a virus that would infect horseshoe bats, especially if you had knowledge of other viruses that infected horseshoe bats. However, if it could not infect horseshoe bats, then that would be pretty convincing evidence that it was a fake sequence.
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map
6/6/2020 06:09:14 pm
Also, with regard to sample being used up. If you isolate a sample and store it at -80, than at some time do a partial sequence, but still have sample enough to do a full sequence at a later date. A date in which by the partial sequence you previously did tells you that the sample could be extremely important because it may the closest thing you have to a virus causing a major pandemic. Then it is not a great idea to run out of that sample, particularly if you can just use some of the sample to infect cells and have the cells make as many copies as you want so that you never have to run out.
John F. Signus
7/22/2020 10:05:11 pm
https://drive.google.com/file/d/1XrgovgELzNHb1wWxTrkX1OooBSFv_Ysn/view?usp=drivesdk
John F. Signus
6/8/2020 06:38:54 am
https://zenodo.org/record/3885333#.Xt48CzmjeUk
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John F. Signus
6/18/2020 08:09:45 am
https://drive.google.com/file/d/1Xp1zBf2d-hu32XSKkyJ7UBOg9ZHuAURS/view?usp=sharing
Jerry K
6/6/2020 10:27:21 am
Anyone seen this yet?
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Brian
6/6/2020 06:29:12 pm
WTF is going on? Now MALARIA on top of HIV? This is like ordering supreme pizza with everything on it! Shame on Chinese virologist! Or whoever behind this...
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M-Z-1-2-3-4
6/6/2020 07:07:15 pm
HCQ (plus Zinc Sulfate) is an effective treatment for covid-19 esp. in early stage.
Jerry K
6/7/2020 04:16:35 am
Perez is finding Plasmodium yoelii in a different part of SARS-CoV-2.
map
6/6/2020 07:47:01 pm
The hypthesis is that HCQ acts as a zinc ionophore, meaning that it gets zinc into cells. Zinc in known to inhibit a major enzyme of the virus. HCQ has other effects on cells. I think it prevents vesicles from forming or fusing with the membrane. I am not sure. The other effects may be more important in malaria, but I do not think getting zinc into cells is thought to be important in its role against malaria becasue it does not seem to be given along with zinc when used for other diseases.
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Mike
6/11/2020 11:06:44 am
Has the protective study of HCQ been done like it was on SARS?
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Henri
6/7/2020 02:58:32 am
Javier,
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Not.qualified
6/7/2020 04:47:34 am
Nerd.has.power or John Signus (especially!)
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Andrea Montelaro Bergeron
6/7/2020 05:58:07 am
To summarize, if the virus were NOT man made, shouldn’t evolutionary evidence of the kind detailed in the above article exist in abundance?
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John F. Signus
6/8/2020 06:41:42 am
This is exactly why the complete lack of persistent mutation of SARS-CoV-2 in the human population is extremely strange!
Nerd has power
6/10/2020 03:34:05 pm
I agree with both Andrea and John. The second paper John listed (done by Chan and colleagues) made it crystal clear. SARS-CoV-2 lacked signs of human adaptation, which is in great contrast to SARS. SARS-CoV-2 did not seem to come from an animal host. Instead, since the very beginning, it is more than ready to use human ACE2 to infect human cells and is showing the level of comfort that only a well-adapted virus would enjoy.
Henri
6/7/2020 10:45:24 pm
NerdHasPower,
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Javier
6/8/2020 02:41:41 am
Henry please,
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John F. Signus
6/8/2020 06:45:53 am
With samples that were being used up, This is basically the "Null Hypothesis" claim. They were stemming debate. also, the bat reads in TG13 points to Hipposideros Armiger--which is a Bat-derived cell line commonly used for growing viruses.
John Kelleher
6/8/2020 01:40:34 pm
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M-Z-1-2-3-4
6/8/2020 05:12:32 pm
https://www.preprints.org/manuscript/202006.0044/v1
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Nerd has power
6/10/2020 03:43:53 pm
Thank you for posting it. I think Javier brought it up in an earlier post too. It is very brave for these authors to stand out and publish such an article. Of course, their science is solid too. Doesn't matter whether they were inspired by information presented here or not. What is important, and telling, is that experts in the field, with varied expertise, are raising similar concerns ---- whether or not RaTG13 truly exists in nature. Shi and WIV should formally respond to these concerns.
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John Kelleher
6/8/2020 08:15:21 pm
Norway scientist claims report proves coronavirus was labe made.
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Andrew M
6/9/2020 02:20:43 am
It is not a different article. It is the same article which has been substantially revised in response to criticisms received (extending to matters of clear fact). The title has also been revised to reflect the resulting change in tone.
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Brian
6/9/2020 03:19:43 pm
No, the paper cannot be changed after publication. the author should retract the paper....and present the reason...Normally, The critics should put some kind of letter to editor that for example, person x, y from university of WMD, would like to challenge the findings due to these reasons...
John F. Signus
6/18/2020 08:12:22 am
https://techstartups.com/2020/06/07/norwegian-scientist-birger-sorensen-claims-coronavirus-lab-made-not-natural-origin/
Robert Cartwright
6/9/2020 02:35:35 am
Good morning, maybe you already know this https://pubmed.ncbi.nlm.nih.gov/32387564/
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Nerd has power
6/10/2020 04:03:10 pm
Interesting article. Thanks for sharing. However, I would not be able to offer any insights for your final question -- the resolution there is, in my opinion, not down to individual mutations. Also I can't say that I'm convinced there are insertions of HIV sequences in the SARS-CoV-2 genome. Maybe someone else here could provide that help.
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Robert Cartwright
6/9/2020 03:03:17 am
Maybe this image can be of help to the experts for a comparison...
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Roger Rabbit
6/9/2020 08:47:42 pm
Regarding the article "Emergence of genomic diversity and recurrent mutations in SARS-CoV-2"
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Javier
6/10/2020 02:40:48 pm
Too much words, too much things.
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yano
6/10/2020 06:12:46 pm
"This unprecedented genomic resource has already provided strong conclusions about the pandemic. For example, analyses by multiple independent groups place the start of the COVID-19 pandemic towards the end of 2019 (Table 1). This rules out any scenario that assumes SARS-CoV-2 may have been in circulation long before it was identified, and hence have already infected large proportions of the population."
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Nerd has power
6/13/2020 08:23:09 am
Yes, powerful bioinformatics studies prove the same point: SARS-CoV-2 was well adapted to the human population since the very beginning. Where else can the adaptation take place except for in a lab? It is becoming even more clear.
John Kelleher
6/10/2020 08:02:13 pm
This is the Sorensen's paper . Andrew M inquired about the statements concerning the Lab Made hypothesis.
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Andrew M
6/11/2020 02:01:23 am
So the the article's alleged statement that the virus was laboratory made consists solely of the ambiguois use of the phrase "inserted sections". Thanks for explaining. Anyone unfamiliar with his history may be interested to know that Dearlove has considerable past form for mis-interpreting, re-interpreting and over-interpreting information sources. The most glaring example was his support for the famous "dodgy dossier" which falsely gave Iraq's possession of weapons of mass destruction as an excuse for launching the 2nd Gulf War. There are others. If Sorenson's research has truly led him to this conclusion (I discount Dalgleish who has no relevant background), there will be press interview material somewhere where he discusses this, no?
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yano
6/11/2020 02:30:12 pm
https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1.full
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Nerd has power
6/13/2020 10:04:02 am
Thanks for sharing it. The paper also indicated that, for these patient-derived SARS-CoV-2 viruses, amino acid mutations have occurred in multiple places in the extended region of S2 (605-1124), where RaTG13 and earliest SARS-CoV-2 share 100% amino acid identity. Again, for a region that is clearly able to accommodate mutations, how can a bat virus share 100% sequence identity with the virus that infects humans (earliest isolate)?
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Brian
6/11/2020 04:40:57 pm
Some Chinese network such as CNN promoting this preprint paper that still, the paper look interesting:
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yano
6/11/2020 09:46:59 pm
This is what a real animal-to-human virus transmission looks like.
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yano
6/11/2020 09:54:49 pm
SARS-COV-1 2003 by the way
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gsgs
6/12/2020 06:28:23 am
these insertions at the cleavage site are quite common in influenza.
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yano
6/12/2020 07:47:14 am
https://www.sciencedirect.com/science/article/pii/S1567134820301829
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John F. Signus
6/18/2020 08:15:14 am
That is in INFLUENZA viruses. No sign of this happening in Lineage B betacoronaviruses at all. SARS did not get a FCS even after extended hth transfer.
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Bugs Bunny
6/13/2020 05:05:39 am
New study on D614G being widely hyped in the media.
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Andrew M
6/13/2020 02:51:55 pm
Is it really being widely hyped in the media? Maybe you could give some links. I've not seen it mentioned anywhere except here. Moreover, having read the article, I'm not convinced it has any great significance.
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Rayne
6/13/2020 06:57:03 am
Great post!
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Nerd has power
6/13/2020 10:24:03 am
Thank you very much for the suggestions. Yes, I did not go into depth in explaining positive and purifying selections. But the subsequent discussions have covered this aspect. I think I will leave the article as it is and let the comment sections do the job of explaining it.
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John F. Signus
6/18/2020 08:17:33 am
https://drive.google.com/file/d/1Xp1zBf2d-hu32XSKkyJ7UBOg9ZHuAURS/view?usp=sharing
evidence
6/13/2020 07:25:31 am
Re: Further hint for VERO E6 cells as likely intermediate host (prior to FCS insertion, evidence given by J.F. Signus and other)
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Nerd has power
6/13/2020 10:33:13 am
Interesting point! Thanks for sharing. Maybe some virologist would look into this aspect. It is also possible that they have done animal work after Vero cell passages. So the virus could be a bit more ready for dealing with human-like innate immunity. My two cents.
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evidence
6/16/2020 09:55:23 am
Re: NerdhasPower.
Chantilly
6/13/2020 03:58:54 pm
I thank everyone for contributions to this blog. It is certainly lays out a convincing argument that the virus is lab produced. I do, however, have a question. While the virus has been globally impactful, it is has not been completely devastating. The actions of the CCP early on (building large hospitals in 10 days, welding apartment blocks shut, and fumigating city centers, 24/7 incinerator operations, ...) seem indicative of a severe impact, or at least a severe expected impact. Yet, while not acceptable, the death toll outside China appears to be lower, possibly considerably lower. Does anyone wish to speculate on an epidemiological reason why this might be the case? Is it possible that as a bioweapon the virus has been a disappointing success (from the viewpoint of those that released it) outside of China? If so should we prepare for round 2, because in war there is always a round 2.
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Pete Ross
6/13/2020 09:35:33 pm
Good question!
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Shinara
6/13/2020 11:26:38 pm
Sounds like the usual wumao misdirection campaign.
Jenny
6/13/2020 11:45:05 pm
It sounds like the right direction to follow.
CCP is NAZI
6/13/2020 11:48:22 pm
Stop sidetrack the discussion. You are just trying to throw in conspiracy theories to deflect the spot light on CCP - a typical CCP propaganda and a trick by the Global Times shills. The quickest and easiest way is always transparency from CCP. They are stonewalling from day 1 and their further actions to destroy evidences speak loudly of their complicity in their role in the pandemic to say the least.
Jenny
6/13/2020 11:54:11 pm
What about a common vaccine program gone wrong paid by USA and China with leak in USA? A virus discovered first in USA 96% close to the one carried by a Chinese bat would have immediately raised the question if it could be natural.
CCP is NAZI
6/14/2020 12:00:44 am
Ya, thanks to CCP infiltrated Obama who used tax payers' money to fund NIH who then outsourced the fund to WuHan P4 lab that was not developing vaccine but bioweapon. Still, my questions above were never answered by any CCP PRO.
yano
6/13/2020 09:21:27 pm
pre print
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Pete Ross
6/14/2020 04:40:19 am
There are dangers to digging too deeply into the events surrounding the origin of this 2019-2020 COVID pandemic, as a possible outcome is that one or more nations perceive correctly or incorrectly that an act of war has taken place.
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yano
6/14/2020 07:41:28 am
"Why has this SARS-2 (CoV-2) pandemic been the subject of intense mass media psychological warfare"
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Jenny
6/14/2020 08:04:29 am
Many virologists might be directly involved and many might be concerned to lose grants for their research and the shame on virology. This sadly comes before the pity for who died. They do not care to risk the next pandemic with their experiments.
Nerd has power
6/15/2020 04:15:25 am
Very good points, Yano and Jenny. If there is someone who is always trying to protect American people and American interests, it is President Trump. HCQ and his claim that this virus is lab-made are two good examples.
Chantilly
6/14/2020 08:08:15 pm
Covid19 was manufactured. It was then released either accidentally or on purpose.
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Alesara
6/14/2020 08:21:18 pm
If for Hong Kong, then also for Taiwan. Unfortunately for the CCP, Taiwan knows the CCP well enough not to get hoodwinked by a CCP/WHO combination public health misinformation attack.
Nerd has power
6/18/2020 01:27:04 pm
Whether it was intended for Hong Kong or it was a "small-scale" human experiments getting out of control, the CCP knew what the virus was. Importantly, one has to be reminded with these facts: 1) the CCP had Zhengli Shi publish a fabricated sequence of RaTG13 after the outbreak took place; 2) the CCP stopped all the domestic travels from Wuhan and yet allowed international flights to run out of Wuhan, freely, for weeks. It's pretty obvious to me that at least some of what happened was intentional.
Alberto
6/14/2020 09:58:01 am
I am sharing my work with you, I sent it to 3 Journals and it was rejected. So, I uploaded it to Researchgate:
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yano
6/14/2020 04:59:06 pm
Yes, papers have been written about how viruses can be constructed and are fully functional at replicating. In 2002. This is not new technology.
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Nerd has power
6/18/2020 01:09:43 pm
Thank you, Alberto, for publishing your article and sharing it here. Yes, there is no doubt that voices on this side are being suppressed. But I don't think that would last forever. Every little bit counts. All we have to do is to keep adding facts. Great and courageous work!
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yano
6/14/2020 05:01:59 pm
@Jenny
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Dobaman
6/15/2020 04:46:15 am
Everyone should watch the latest "This week in Virology" podcast with Ralph Baric and watch his reaction to a "GoF" comment made. Its hilarious. :-)
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Ralph's Cousin
6/15/2020 12:04:44 pm
In the "This week in Virology" podcast found here https://www.microbe.tv/twiv/
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Henri
6/16/2020 01:50:39 am
I detected no 'stunned silence' and no ' nervous laughter'.
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Pete Ross
6/16/2020 02:48:37 am
Is that good or bad?
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Henri
6/16/2020 06:47:01 pm
Neither
Brian
6/16/2020 03:34:11 pm
Ralph and Shi , the "old coworkers", should be in the court of law right now providing evidence that they are not guilty. The FBI, by now, should have raid their homes . The fact that none of these happening means that something really really is wrong! The fact that they still proudly broadcast podcast, and laughing to dead bodis, means that there is something really really Fucked up! You got to be serious and boycott and socially shamed these so called scientist? Why you even listen to them? They should come clean with some kind of video confession... Is there not enough evidence that the are creating GOF variants? Why there is no prosecution? This is just 9/11 all over again for your generation!
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Not.qualified
6/16/2020 06:26:47 pm
Brian you are exactly correct, Ralph & Shi should be held accountable for this BEAST they intentionally willfully created...it is their dog now biting ALL OF HUMANITY
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Not.qualified
6/16/2020 07:20:22 pm
Need.has.Power, John F. Signus, & other GenBank users:
Nerd has power
6/18/2020 01:54:10 pm
Thanks for the info. The timing of this upload is very interesting. I did a quick blast and saw that the nucleotide sequence of this virus is 82% identical to that of SARS-CoV-2. I think it would be very hard to detect anything in terms of whether or not SARS-CoV-2 can be traced back to this virus.
Not.qualified
6/17/2020 05:00:42 am
Nerd Nation please continue the debate in the meantime...above request may take a sec :)
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Not.qualified
6/17/2020 10:27:10 am
P.S. (Brian, especially!) ...meaningfully the article I reference above lists Shi & Baric together as co-authors...
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Brian
6/17/2020 03:24:05 pm
Sch014 that they engineered in 2015 may not be related to ratg13.
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Brian
6/20/2020 08:44:56 am
Look like more than 50 scientist are in trouble with 399!!!! To go...
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Arnaud
6/18/2020 07:39:28 am
From https://en.m.wikipedia.org/wiki/201_(number)
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Ted
6/19/2020 01:40:08 pm
@ Nerd has power, @ John F. Signus. A published protein alignment of the S region is interesting and seems worthwhile to note here. As in the alignment in the article above it compares SARS-CoV-2 (Wuhan-Hu-1) to a mix of bat CoVs (including ZXC21 and ZC45) and CoVs from the prior SARS pandemic. A useful addition is that it also includes RaTG13. Since it is published it can be easily cited. @ Nerd, all your related observations in your two articles appear to apply to this alignment published in:
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gsgs
6/20/2020 08:02:41 pm
may I ask people here,
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Brian
6/20/2020 10:18:42 pm
Your question whether this site belongs to a political party is nonsense.
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gsgs
6/22/2020 11:21:14 pm
Brian wrote on Jun20:
Alesh
6/23/2020 01:05:30 am
“And here the lab-origin is obviously "a Trump's" thing..... others may have
yano
6/21/2020 11:49:28 am
" ignore evidence for a natural origin"
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gsgs
6/22/2020 11:23:06 pm
Yano ,
Jenny
6/21/2020 01:11:56 pm
The evidence provided so far for a natural origin comes from a highly biased study in Nature, the Proximal Origin of SARS-CoV-2
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Nerd has power
6/21/2020 09:31:35 pm
My first article was written in late Feb. By then, no republicans or democrats had said anything about a lab origin of the virus, as far as I can remember. I was convinced by the scientific evidence and logic, not by American politics. If the Democrats had first come out and spoken what I believe is the truth, I would praise them just as much.
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evidence
6/21/2020 02:32:54 am
Re: New experimental support for RBD pre-adaptation
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yano
6/21/2020 11:41:03 am
How does this even happen in nature? This seem totally crazy to even suggest a RBD pops out of nature fulling adapted to human cells.
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Nerd has power
6/21/2020 09:38:06 pm
Thanks for sharing this paper. It is in line with Alina Chan's paper, which revealed that the SARS-CoV-2 virus was well adapted for infecting humans from the very beginning.
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Ted
6/21/2020 02:29:35 pm
Yuri Deigin, the author of the Medium article much discussed in the comments above, with Rossana Segreto, published a preprint this month on ResearchGate. Worth reading.
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Nerd has power
6/21/2020 09:41:59 pm
Thanks! I have seen this preprint. It's wonderful. Yuri also had an interview with Bret Weinstein, which is worth watching although it's a bit long:
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gsgs
6/23/2020 02:59:04 am
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John F. Signus
6/24/2020 06:13:26 am
https://drive.google.com/file/d/1tW8g6tJQ1zsDBg3W-EmnpeX7fpiirP6C/view?usp=sharing
Nerd has power
6/24/2020 07:26:38 pm
Thanks, John! I do plan to dig a bit more on the syn/non-syn analysis. Will definitely include SARS and YNLF31C in there.
Nerd has power
6/23/2020 08:55:47 pm
Thank you for sharing your work and opinion. I guess you were referring to Figure 3 in "RaTG13 is fake" and arguing that having lots of synonymous mutations could be totally normal for certain viral proteins.
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Pete Ross
6/24/2020 02:34:21 am
So pro-clotting peptides are a consideration when examining the genome of a COVID-agent, such as SARS-CoV-2.
gsgs
6/24/2020 08:23:24 am
Nerd has power
6/24/2020 08:17:39 pm
Thanks, Pete, for sharing the info. I don't have such expertise either. Hopefully someone else could be inspired and take it on.
Mr1k
6/23/2020 09:09:47 am
Isn't it also strange they actually do not know where the original SARS origin came from?? But it must be zoonotic...
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Brian
6/23/2020 04:29:05 pm
I was listening this evening to the Dr. Fuci and his team in congress hearing. No single question raised about the origin of this virus by neither parties. Why is that?? There was No senator Tom Colton present there...who is supposedly the front runner of lab-made virus comments ''at the political level''. Where he was?....The fact that both Republican and Democrat were totally shut down today again means that you need to review my comments above...and I don't want my IP address block again...so good luck! And enjoy daily increase of killing spree...
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yano
6/23/2020 08:48:38 pm
I think there are a couple of things going on.
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Pete Ross
6/24/2020 05:30:16 am
OK yano,
Pete Ross
6/24/2020 05:37:59 am
Capitol Hill politicians and insiders send Hundreds of Billions of dollars to NATO every year unless there is a war like Afghanistan or Iraq (then it’s trillions) with the understanding they want a big chunk of that back. That’s why NATO would have the motive to BioWeapon Trump far more that China. When you see NATO operatives and couriers all around something when the COVID-19 like the Wuhan NATO Military Games, you have to think about which organizations have the means, motive, and opportunity to do the Bioweapons test of the relatively safe strain of COVID-19 in October 2019. Those are the same orgs with the means, motive, and opportunity to do a more lethal version of COVID-20 in October 2020. Beware the angry teenager screaming for more and more money and less and less responsibility. NATO has the motive, not China, to BioWeapon
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Brian
6/24/2020 11:40:40 am
There is also unintended consequence of unleashing a wild virus into human population such as D614G mutation. ...To their surprise!
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Nerd has power
6/24/2020 12:17:14 pm
What matters at the moment is not who has the biggest motive to create a bioweapon. It is who created this particular coronavirus-bioweapon and who released it to the human population. What I can see is 1) only the CCP has the backbone for engineering this virus; 2) the CCP fabricated the RaTG13 virus as a cover-up; 3) the CCP silenced whistleblowers to conceal the information at the beginning of the outbreak; 4) the CCP also most likely fabricated the pangolin coronaviruses to cover up things; 5) the CCP blamed everybody for being the source of the virus when all evidence points to Wuhan; 6) the CCP got really mad at Australia for proposing an independent investigation of the WIV and the P4 lab.
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Pete Ross
6/25/2020 01:42:36 am
There is strong, irrefutable evidence of collusion with other powerful syndicates, in particular the corporate main stream media and tech giant social media platforms, both deploying psychological warfare active measures that are painfully obvious.
Annette
7/25/2020 03:51:44 am
https://www.sciencemag.org/sites/default/files/Shi%20Zhengli%20Q%26A.pdf
yano
6/24/2020 09:20:33 pm
I don't believe NATO did any bio-weapon. I believe it was either a lab accident in China or a purposeful spiteful release of the virus in China, by lab personnel, to take down the CCP. As regime destruction history is repeating itself. Maybe someone in Shi's lab. A hateful bitch that hated the CCP.. Hear that somewhere by the way.
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CCP is NAZI
6/24/2020 11:55:09 pm
The only country that has the strongest motive to develop bio weapons is China who smuggled virus to China either from the P4 lab in Canada:
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Jimmy Kudo
5/31/2021 12:53:51 am
Seems like you're still stuck in ancient China...
gsgs
6/24/2020 07:48:04 am
I meant, SARS2 may have evolved in another species for decades
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Nerd has power
6/24/2020 12:27:24 pm
Your argument is under the assumption that the S2 protein is doing different things in different host and therefore could face different selection pressures. I don't think that is the case though. S2 maintains trimer formation and mediates membrane fusion with its freed N-terminal fusion peptide. That is true in every host, nothing more and nothing less. S2 has seen a fair amount of amino acid mutations in different SARS viruses, in different bat coronaviruses, and in different SARS-CoV-2 viruses. Only when it comes to comparing RaTG13 and SARS-CoV-2, this natural trait is gone. To make things worse, the syn/non-syn ratio has skyrocketed to 44:1. At least one of the two is non-natural.
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Pete Ross
6/25/2020 02:12:55 am
What was Dr. Peter Duszak, another foreign national, of EcoHealth Alliance, doing in China in October 2019?
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Andrew M
6/25/2020 12:46:59 pm
It's a problem Nerd has setting up a site like this. Along with serious scientific discussion of his ideas and spin-off therefrom, it acts like a lamp to moths for every lunatic and conspiracy theorist with a particular interest in this subject. The consequence is that the majority of people visiting will read this nonsense and write the site off, along with Nerd's theories about the origin of SARS-Cov-2.
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yano
6/25/2020 01:26:53 pm
The science is still good and stands no matter how many theories show up. I don't see this as a negative thing.
alesh
6/25/2020 07:38:33 pm
I’m open to deleting these posts, including those obviously wumao, fifty-center coordinated disinformation attempts.
alesh
6/25/2020 07:36:03 pm
“What happened that the CDC lost over a month of actively containing the SARS-CoV-2 outbreak due to reliance on test kits that turned out to be contaminated with the virus?”
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Brian
6/25/2020 10:03:56 pm
Well, a fruit called pawpaw become test positive. that is kind of weird. the point is there is no similar virus in this food so the term false positive may not work here! We don't know the prevalence of this kind of errors since there won't be any followup!
CCP is NAZI
6/28/2020 11:57:59 pm
Those scientists, real or fake, politically correct or incorrect, and those non scientists including WuMao(i.e. 50 cent army) should watch this warm up video to review how this CCP virus was started and spreaded to the world:
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6/25/2020 01:18:40 pm
Dear Sir/Madam:
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alesh
6/25/2020 07:42:10 pm
Amateur ploy to unmask.
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Nerd has power
6/28/2020 04:07:25 am
Thank you, Alesh. I appreciate your help, but I agree that Greg did not mean to harm anybody. I blame the CCP for making us all supersensitive on things that we shouldn't be sensitive about. Talking about all the negatives the CCP brings........
Nerd has power
6/28/2020 03:58:30 am
Hi Greg, sorry for the delay in responding. Thank you for your efforts in uncovering the truth about this virus. As you would understand, I don't yet feel comfortable revealing my true name. I understand how awkward it could be to cite a name like this in a serious writing. However, another pseudonym wouldn't improve the situation much, in my opinion. If you could manage not to mention the name or simply call me an anonymous scientist, it would be great. Thank you again and please share the link to your article here once it's published. I believe people here would be very interested in learning your insights.
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6/28/2020 04:37:27 am
Thank you, Nerd has Power:
Nerd has power
6/28/2020 07:29:39 pm
To be honest, I'm not convinced that any HIV sequence has been inserted into the SARS-CoV-2 genome. I would be happy to be proven wrong though. 6/25/2020 08:31:46 pm
I do not know how any nefarious intent could be inferred from my original post.
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6/28/2020 11:29:40 pm
Many thanks for your answer. If you don't mind, I would like you opinion on the following two points.
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Nerd has power
6/29/2020 08:03:47 pm
No problem, Greg. You are correct that HIV does have furin-cleavage site. I agree that they are simply following the knowledge/examples from other viruses. From what I know, the effect of furin-cleaveage site in infectivity and pathogenicity was best validated in influenza viruses, although there were also such gain-of-function examples in coronaviruses. I think it's fair to say that they were just following the knowledge that adding a furin site here makes a virus super bad.
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Brian
6/29/2020 08:22:47 pm
not to disagree , just want to add that this bioweapon seems to trigger multiple pathways including CD147 pathway and this is the one that may cause a long term chronic disease...
Nerd has power
7/1/2020 02:12:47 pm
Thank you for sharing the link! 7/1/2020 03:21:57 pm
Yes, indeed: thanks.
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Nerd has power
7/2/2020 08:43:02 pm
I don't know how much Shi was involved in the actual creation. I don't believe Shi single-handedly did the whole thing and leaked it out by accident or on purpose. I do believe that, at this point, if there is anyone who could be the scapegoat for the CCP, it would be her. I hope she doesn't suddenly die and leave a letter of "confession". Her being missing is not a good sign -- the real criminals might be planning a scene.
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CCP is NAZI
7/2/2020 09:01:18 pm
https://www.newindianexpress.com/world/2020/may/02/chinas-missing-virologist-with-secrets-of-covid-19-origin-denies-defecting-to-west-2138364.html 7/2/2020 10:09:18 pm
As you can see "CCP is NAZI" was the quicker off the mark with the answer than I was. I agree with you that Shi did not act alone, but she has to take ultimate responsibility given her position. I think it more likely that she is being held incommunicado so that she doesn't have to field any more media questions, particularly about RaTG13. I have read, perhaps here, that she does not have a physical copy of the RaTG13 RNA sequence, which has been "legitimized" in countless articles in otherwise respectable journals.
Babstar
7/3/2020 12:32:03 am
– The most logical explanation is that it comes from a laboratory
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yano
7/3/2020 03:26:05 pm
He gives a 90% probability SARS CoV 2 is from a lab, lol. That was my guess too.
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Lilian
7/3/2020 10:20:43 pm
That’s kind from you. I bet 99.999%. A virus like SARS-CoV-2 with that RBD and that special furin cleavage site has almost no probability to originate naturally. All the closest “natural” CoVs sequences provided so far, RaTG13, pangolin CoV form Guangdong and the perfect timely discovered RmYN02 smell of fabricated.
gsgs
7/6/2020 11:06:44 pm
Lilian , I give you another factor of 100 and bet $1 against your $1000
Lilian
7/7/2020 01:01:41 am
gsgs: you might win. They are really good in finding what they need in order to prove the natural origin of SARS-CoV-2. Andersen wrote: “Given the level of genetic variation in the spike, it is likely that SARS-CoV-2-like viruses with partial or full polybasic cleavage sites will be discovered in other species.” 7/3/2020 11:46:41 pm
At https://www.minervanett.no/corona/the-most-logical-explanation-is-that-it-comes-from-a-laboratory/361860, Norwegian scientist Birgir Sørensen says that SARS-CoV-2 attaches itself to receptors in the upper respiratory tract in addition to ACE2 receptors, which are found in the lower tract. The point is that this other receptor's vulnerability may explain the order of magnitude difference in SARS-CoV-2 cases and fatalities.
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Lilian
7/3/2020 11:57:09 pm
"As with SADS, the similar pathology associated with Covid-19 points in the direction of a different and more promiscuous attachment/ co-receptor like CLEC4M/DC-SIGN driven by a positively charged Spike trimer surface."
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7/5/2020 11:40:42 pm
Thank you, Lillian:
Jenny
7/4/2020 01:02:29 am
The scientists who signed this letter in The Lancet:
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CCP is NAZI
7/4/2020 08:30:29 am
Am I reading this alright? The criminals now want to take victims to the court instead of the other way around? If this CCP virus were confined within its origin in the first place, who on earth would give it a damn shit as to whether CCP virus has a natural origin or a lab made product?! Not even the people living in Wuhan, as Chinese Communist Party have been treating their own people as disposable objects whose everything including their homes and organs all belong to the Chinese Communist Party which explains why Chinese Communist Party would live harvest even children's organs! See how cruel they are! https://twitter.com/newyorkluo/status/1278686298547552262 As you see, the kids' bodies were even nicely sewed up after their organs were harvested.
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CCP is NAZI
7/4/2020 08:45:32 am
Just because the world didn't hold Chinese Communist Party accountable for their SARS, there comes CCP virus today.
yano
7/4/2020 09:22:29 am
From the Lancet => "We speak in one voice. To add your support for this statement, sign our letter online. LM is editor of ProMED-mail. We declare no competing interests."
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7/5/2020 11:13:20 pm
Can someone please explain to me what the (1-7) in Angiotensin (1-7) means?
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Lori
7/6/2020 10:59:47 pm
Hi Nerd Back again I thought you might find this interesting.
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Nerd has power
7/11/2020 08:49:02 am
Thank you for the info! Yes, this is definitely interesting. The twitter investigative scientists crew has done a spectacular job digging this info out. I barely managed to keep up with their progress.
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evidence
7/7/2020 05:56:59 am
RE:
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evidence
7/7/2020 06:01:00 am
[ Zhe Liu et al.: Identification of a common deletion in the spike protein of SARS-CoV-2
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Brian
7/7/2020 10:23:09 am
The problem is ''IF'' the assumption of lab origin is correct, ''THEN'' it can be ''REINTRODUCE '' to population in different countries ''ANYTIME'' as they wish! The source need to be destroyed NOW. Who is going to do that? Mr Biden? Even Trump try to ignore it! the racial tension was made to distract people and it was not enough. now what? There is something really really ...ucked up here!
Nerd has power
7/11/2020 09:07:08 am
Great analysis. If it becomes attenuated naturally by losing the FCS, it would be good news for us human. There are many uncertainties though, including Brian's concern that someone (the CCP) will keep sending the original recipe to your doorstep. It has to be cut at the source.
evidence
7/13/2020 08:20:07 am
Re: FCS likely to remain for human infections
FreeFreedomain
7/7/2020 09:41:08 am
If ZXC21 and ZC45 are 97% similar and CoV2 is 95% similar to both ZXC21/ZC45. Why having identical E protein when similarity is 97% is ok and natural, but when similarity is 95%, then it's nearly impossible to have identical E? There is only 2% difference between these two cases.
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Nerd has power
7/11/2020 09:11:24 am
SARS-CoV-2 is 89% identical to ZC45/ZXC21 on the gene level, not 95%.
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FreeFreedomain
7/12/2020 11:21:02 am
Thanks for getting back to me!
Ted
7/8/2020 11:43:52 am
The tweets by Alina Chan (post doc at MIT and Harvard), @Ayjchan are remarkably interesting to read. She is also one of authors of the paper cited above that claims that “SARS-CoV-2 resembles SARS-CoV in the late phase of the 2003 epidemic after SARS-CoV had developed several advantageous adaptations for human transmission.” https://www.biorxiv.org/content/10.1101/2020.05.01.073262v1
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Nerd has power
7/11/2020 09:24:44 am
Yes, Alina Chan and her co-author Shing Hei Zhan have been fantastic in revealing critical facts embedded in the genomes of relevant viruses. They also published a preprint questioning all the pangolin coronaviruses that the CCP labs have published recently:
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gsgs
7/8/2020 11:49:27 pm
I just found this recent French paper about SARS2-origine
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Andrew M
7/9/2020 03:21:54 am
This is a really good, readable, thorough, well-balanced article which summarises many of the relevant issues. In passing it explains why the Montagnier/HIV theory is completely "fringe". Correctly (in my view), it concludes that neither natural nor man-made origin can be proven and advocates further research be conducted. Until then, each of us is left with Bayesian inference as a way of deciding what we think is the answer.
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Brian
7/9/2020 04:33:29 pm
The question is why they did not reference Nerd article that the ratg13 is potentially fake. They seem that review all controversial aspects but not this one.
Nerd has power
7/11/2020 10:49:42 am
Thanks for sharing it. I would have to critical about this paper, although I praise them for officially raising the possibility that SARS-CoV-2 coming out of genetic manipulation. Given it's a preprint, it would be hard for the authors to speak in full what they truly believe. However, unfortunately, in their analysis, they placed heavy weight on RaTG13 and the pangolins viruses, which are clearly problematic and even proven fraudulent. In addition, they mentioned that the RBD of SARS-CoV-2 could not be obtained from genetic "copying" from SARS RBD because phylogenetic analysis of the RBDs categorized the two viruses into two distant groups. I hope they realize that, if someone is carrying out genetic manipulation, they would most likely avoid a direct "copy/paste" and would manage to make things look further apart. The fact that the two look further apart does not exclude genetic manipulation of the RBD here. As I pointed out in my article, all the essential residues are "copied" over and changes are in non-essential sites.
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Andrew M
7/9/2020 05:33:32 pm
Brian M - you have left no "reply" box at the end of your comment, yet you ask me questions. The French scientists summarise various articles in the scientific literature. Nerd hasn't written such an article for them to comment on. Why might they even be aware of his website? So I have little concern about their lack of comment on a potential faking of RATG13, which is not an obvious inference from the scientific evidence available, nor do I think magic happens all the time. That the earth originally gained its water from "meteorites" (asteroids actually) is one of the main theories on this issue, so maybe you chose a bad analogy there.
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Brian
7/9/2020 08:04:46 pm
Andrew: I don't know how to do that here...sorry about that...
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Andrew M
7/10/2020 01:49:02 am
Brian - this time there is a reply box and though you request me not to answer, I want to make the following point clear for the benefit of othere readers. If you read the paper upon which I commented, you would understand that the appearance of short sequences common to certain strains of HIV is not statistically significant - ie random coincidence is a perfectly adequate explanation. My hunch would be that the same result would be obtained for malaria if someone performed the analysis. Note that Nerd discounts the HIV hypothesis too.
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Brian
7/10/2020 03:40:48 pm
That is fair assessment...but how about combining all these probabilities together.
CCP is NAZI
7/10/2020 11:31:44 am
Li-Meng Yan told Fox News that she believes China knew about the coronavirus well before it claimed it did. She says her supervisors also ignored research she was doing that she believes could have saved lives:
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Andrew M
7/10/2020 03:51:11 pm
Og dear Brian. No reply box again. You should try at least to get the hang of this simple principle. For sure design a statistical test that all these things can't be random. Given that an individual test for one of them shows just randomness, maybe that's hard. But to say "they can't all together be random" - that is not science, just sensationalism.
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Brian
7/10/2020 05:11:19 pm
This combined probability should be statistically calculated by some young phd guys from here.
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Andrew M
7/10/2020 05:35:17 pm
Nonetheless you've succeeded in attaching a reply box again.
Alesh
7/10/2020 06:46:39 pm
Sometimes you wonder whether the CCP is intentionally trying to derail the RatG13 is Fake comment section by employing trolls who frustrate us all by launching into multiple useless tangents.
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7/10/2020 06:32:55 pm
I’m sorry if this question has been asked, but what is the evidence for claiming that the theory of HIV insertions has been debunked.
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Brian
7/10/2020 07:01:27 pm
Greg
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Greg
7/10/2020 07:55:44 pm
Thanks, Brian, but I understand the renin-angiotensin cycle. I just don’t know what the “1-7” means. Does it refer to certain molecules on a long chain? Angiotensin I and II are written with roman numerals; 1-7 are Arabic numerals. So far, web searches have not helped.
Brian
7/11/2020 07:40:51 am
Greg 7/11/2020 12:22:36 pm
I'm not a bioinformatics person either, but P test is likely not appropriate when comparing the syn/non-sym differences. Some expert can prove me wrong.
Andrew M
7/11/2020 02:30:51 am
It's in the french article linked above.
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Thanks, Brian and Andrew.
Ted
7/11/2020 08:37:12 am
For discussion:
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Nerd has power
7/11/2020 11:49:00 am
Thank you, Ted. I have briefly commented (7/11/2020 09:24:44 am) on it in a reply to your earlier post. However, let me add that the evidence here contradicts Shi's description that they only went back to the sample after the outbreak started. It is basically another piece of clear evidence suggesting that Zhengli Shi has not been the most honest person on this planet.
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alesh
7/11/2020 07:30:44 pm
I only see 2020 dates on those entries. Where is the 2016/17 dates?
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alesh
7/11/2020 06:06:38 pm
Nerd has power said: “I'm not a bioinformatics person either, but P test is likely not appropriate when comparing the syn/non-sym differences. Some expert can prove me wrong. 44:1 is impossible, not almost impossible. That's my conclusion. The only way to challenge it is to use facts, which I bet you can't find in nature.”
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Nerd has power
7/11/2020 09:26:48 pm
Haha, yes, I have voluntarily highlighted a vulnerable part of my analysis. I welcome all challenges on this issue. If anyone can bring Peter Daszak or Zhengli Shi over to challenge me, it would be fantastic. Shi might simply tell me to "shut my stinky mouth". But that wouldn't work very well here as I demand that the challenge has to be facts-based.
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gsgs
7/12/2020 02:44:07 am
yes, I found some such pairs in Coronaviruses some weeks ago.
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gsgs
7/12/2020 02:52:35 am
[code]
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Nerd has power
7/24/2020 04:16:02 pm
Thank you for sharing the info! They are very helpful. Sorry for not responding earlier. Hope you still would check back on this comment.
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gs
7/12/2020 03:22:35 am
note also the pangolins. These sequences were not known when RaTG13 was submitted.
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Fuddman
7/13/2020 06:06:10 pm
So California is shutting down, again ,after a spike in new cases. Should California react to “new cases” or should they be reacting to some other virus effect?
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CCP is NAZI
7/13/2020 08:21:28 pm
Dr. Lawrence Sellin: Evidence Indicates the China Coronavirus “Most Likely a Product of Laboratory Manipulation”:
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Crocodilite
7/14/2020 01:44:35 pm
Dear Nerdhaspower,
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Crocodilite
7/14/2020 01:47:35 pm
Sub-possibility 3.1. BtSht13 contained an S1 tip that’s substantially different from the S1 tip in SARS-CoV-2. If this were true, this sub-possibility actually degenerates to Possibility 1 above! Namely, this degenerates to the case where RaTG13 was actually real! What was RaTG13 anyway? It was the case of something similar but with a different S1 tip. Since we have already discounted that possibility, sub-possibility 3.1, the equivalent, is also discounted!
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Crocodilite
7/14/2020 02:07:56 pm
Sorry, typo: please scratch out the reference to the furin site in the discussion of "Possibility 1." That reference was meant to have gone into "Possibility 2!"
Fuddman
7/15/2020 01:45:46 pm
"We know something significant was found in the cave in 2013."
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Crocodilite
7/15/2020 10:49:26 pm
The Times piece practically covers the 4991-to-RaTG13 renaming shenanigan with the tone of uncovering a scandal, accuses both the WIV and the government of covering up and continuing the coverup of the deaths of the miners to this date, extensively sources the medical doctor papers and hospital records through extensive digging of buried records, postulates multiple possibilities that the whole thing could have been the result of a lab leak, and as any good investigative journalism would, gives the accused or relevant parties opportunities to respond, some of whom did, unconvincingly, most chose to remain silent.
Crocodilite
7/14/2020 02:01:54 pm
Sorry, typo: please scratch out the reference to the furin site in the discussion of "Possibility 1." That reference was meant to have gone into "Possibility 2!"
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Brian
7/14/2020 06:57:50 pm
Crocodilite. Fyi:
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Crocodilite
7/15/2020 02:28:07 am
Thank you Brian. I had read Yuri’s excellent article before. And I just quickly looked at it again to look for updates--he marked them with “[Updated]” tags. While the article is truly awesome, I don’t believe it answered my question.
Crocodilite
7/15/2020 04:29:31 am
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Crocodilite
7/15/2020 04:31:51 am
Quote:
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Crocodilite
7/15/2020 04:34:09 am
So, we have the following assertions:
yano
7/15/2020 11:47:16 am
Looks like Shi found some viruses in that mine but a fungus was the actual pathogen that sickened and killed the miners. At least this is what this article says.
Crocodilite
7/15/2020 11:29:56 pm
According to the Times piece, from hospital records and interviews of doctors, at the time, all six miners tested positive for antibodies against an unknown Sars-like coronavirus, but Sars was definitively ruled out. And, quote:
Lilian
7/15/2020 12:42:40 pm
In the hypothesis of a purposeful release of the virus it can be interesting to watch this short video where Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), warned members of the incoming Trump administration in January 2017 about the inevitability of a "surprise outbreak" of a new disease.
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Lilian
7/15/2020 10:50:47 pm
Fuddman: there is a Thesis, which has been recently translated in English that describes the symptoms of the miners.
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Crocodilite
7/15/2020 11:50:44 pm
Wow, that looks like a very interesting link!!
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Crocodilite
7/16/2020 04:55:18 am
Wow, just wow! I believe the technical term for this is: “Holy bat shit!!”
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Crocodilite
7/16/2020 05:10:01 am
And the all-important question of why, why did Shi and company hide this entire saga and the existence of the samples, for all these years, the all-important question of *motive* is anyone’s guess!
David Rivard
7/16/2020 10:09:27 am
Are any papers being published that compare the current strains in China with those of the US?
Crocodilite
7/16/2020 12:41:36 pm
Hi David, re: “apologetic comments” about “beyond the scope” of science, well said.
Crocodilite
7/16/2020 12:44:57 pm
Shi has busloads of international collaborators spread all over the world. Indeed, I believe some of their bat poop was sequenced in San Diego. If very dangerous coronavirus needs a little more safety precaution than that, I’m sure she and her huge circle of well-connected cohorts could pull some strings somewhere to have the work done overseas.
Fuddman
7/16/2020 02:25:38 pm
The Nerd running this thread calls Shi Zhengli a liar. And that she released the SARS-CoV-2 as a bio weapon.
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yano
7/16/2020 08:54:12 am
https://www.independentsciencenews.org/commentaries/a-proposed-origin-for-sars-cov-2-and-the-covid-19-pandemic/
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Lilian
7/16/2020 09:24:59 am
Also because a BSL-3 lab seems to be enough to work on CoVs.
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Greg Felton
7/16/2020 11:22:16 am
I have my doubts about this. Genetically modifying pathogens requires BSL4-level security and safety. Scientists have to wear moonsuits, which are not required at the BSL 3 level.
Lilian
7/16/2020 11:58:50 am
Interesting reading on GoF research and biosafety level from 2016:
Marilene
7/31/2020 06:49:10 am
"I bet SARS-CoV-2 was already part of this study before the outbreak."
Brian
7/16/2020 01:26:10 pm
I can add that some of these miners were antibody positive for original SARS1 based on an interview that I heard from Yuri
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Crocodilite
7/16/2020 02:22:48 pm
The Master’s thesis, which was based on hospital records, stated clearly that SARS1 was among the first things they looked for and was able to categorically rule out.
Brian
7/16/2020 04:10:59 pm
sars1 doesn't seem to be totally ruled out above based on your naratives...I think you are trying to make a peace with yourself...Then ...diiiiiing....the furin seq magically inserted into ratg13 ? Sorry to wake you up!
ape
7/16/2020 12:26:05 pm
A new article at Independent Science purports to have a plausible origin story for the virus. They claim there is NOT evidence of "specifically genetically engineered or biowarfare origin..."
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Rocky Balboa
7/16/2020 10:16:16 pm
I think the Latham and Wilson article is an interesting one, but I have a few issues with it.
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Crocodilite
7/18/2020 05:54:42 am
Good points! I’m actually not an expert in this field so I would be very eager to learn from you!
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gsgs
7/18/2020 06:12:25 am
5. the increased 3-7 fold mutation rate due to unusual
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Paolo Barnard
7/17/2020 05:49:04 pm
You feature in this interview of mine to Dr Michael Antoniou at King's College London. https://youtu.be/3WQp2Aqr1ps. A 100% English version of it for private viewings only is here https://youtu.be/ehow-zB_pFs. Paolo Barnard
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yano
7/17/2020 07:19:58 pm
It's pathetic that only three scientist have the balls to stand up and voice their opinions. What kind of world do we live in? It's sick. We are not free if scientist cannot voice their true opinions for fear of retribution.
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Brian
7/17/2020 10:04:41 pm
Dear yano...
Greg Felton
7/17/2020 10:20:38 pm
Brian:
Brian
7/17/2020 10:36:44 pm
well...and haha...The building 7 video is all over the place and again more than 1000 scientist scientifically determined that external forces was in place...there was a scientific paper published that termite was involved...you are so willingly ignorant! do you want me to send you building 7 free fall video? So you can see by your own eye? Is that scientifically enough? ...the point is they unleash this virus ..now you as a scientist tell us who are "they"
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7/17/2020 11:08:54 pm
Someone like you who buys into the bible really has no place discussing physics or any other aspect of scientific investigation. The "Appeal to Authority," which you seem to worship, is a logical fallacy by which a person who cannot form a rational argument hides behind the words of others.
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Brian
7/18/2020 05:51:30 am
Greg
Mr1K
7/18/2020 05:57:45 am
I think its more likely,its a fallacy of the virus at all.
Crodilite
7/18/2020 04:14:21 am
test?
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Crocodilite
7/18/2020 06:12:13 am
(1/4)
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Xoco Latte
8/26/2020 02:24:11 am
Sorry for being so late to the party...
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Xoco Latte
8/26/2020 02:44:38 am
One more thing (and a sorry for some tipos in my earlier sentences):
Crocodilite
7/18/2020 06:14:33 am
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Crocodilite
7/18/2020 06:17:42 am
(2/4)
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Crocodilite
7/18/2020 06:20:50 am
(3/4)
Crocodilite
7/18/2020 06:22:51 am
(4/4)
Pete Ross
7/18/2020 08:41:08 am
info on next bioattack:
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Brian
7/18/2020 03:09:47 pm
Is this real??
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Mr1k
7/18/2020 10:24:11 am
Where is the purified VIRUS????????
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Mr1k
7/18/2020 05:20:33 pm
https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/about-us-cases-deaths.html
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Mr1k
7/19/2020 04:52:01 am
Assuming a death from Covid 19 is not the same as proving a death.Where are the autopsy reports????
Mr1k
7/19/2020 05:11:29 am
The mystery virus and mystery disease fails Koch's Postulates:
Sidney Reilly
7/23/2020 10:40:42 pm
Potentially, very significant findings in this study e.g.
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Fuddman
7/25/2020 09:17:48 am
I receive your new comments via e-mail; but, when I look for them in your blog, I have difficulty finding them.
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gsgs
7/26/2020 05:18:50 am
download the whole thing and search for keywords
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Fuddman
7/26/2020 02:39:48 pm
Thanks.
Nerd has power
7/29/2020 08:57:54 pm
Thanks for the tip, gsgs.
Brian
7/25/2020 03:59:03 pm
I think The link above From Pete Ross deserve some discussion.
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gsgs
7/26/2020 05:24:31 am
Below I take only the first 21000 nucleotides, because there are fewer
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gsgs
8/2/2020 06:20:36 pm
I'd like to withdraw this. Can it be cancelled or a remark included ?
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7/29/2020 07:24:15 pm
Are the SARS-CoV-2 polybasic furin cleavage sites replacements for the SARS-CoV monobasic cleavage sites or are they complementary? IOW, does cathepsin L still cleave SARS-CoV-2 at S2’ and S1/S2?
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Nerd has power
7/29/2020 09:06:20 pm
Furin cleavage site is the added benefit from the virus' perspective. SARS doesn't have it and yet was quite able to survive. Yes, I believe cathepsin L still cleaves both sites in SARS-CoV-2. Having the furin cleavage site in SARS-CoV-2 likely facilitated the processing of the spike, which presumably boosted the cell entry efficiency.
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7/29/2020 09:54:20 pm
Thanks, Nerd.
Nerd has power
7/29/2020 09:58:58 pm
I don't think the S1 would differ in length. The furin cleavage site at the S1/S2 junction is essentially the RRAR sequence. 7/29/2020 11:41:10 pm
I understand, but aren't both cathespin and the RRAR sequences at the S1/S2 junction? Don't two cleavages imply a shorter S1?
Nerd has power
7/30/2020 05:46:44 am
Either would do the work and one cut is sufficient. The length difference here should be tiny and should make no difference in function. S1 is shed off eventually for the membrane fusion to occur, leading to cell entry.
Nerd has power
7/29/2020 09:54:26 pm
Sorry for the radio silence in the past few days. Great discussion on the possible theories of lab origin. I won't be able to comment on each individual thread, but I would briefly say that I still feel comfortably convinced that 1) SARS-CoV-2 is an engineered virus using ZC45 and ZXC21 as the template/backbone and 2) RaTG13 is fake.
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yano
7/30/2020 06:21:48 pm
She should come here and make a few comments. That would be great! She talked about writing a paper explaining how easy it is to make a chimeric virus in 6 months.
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7/30/2020 06:52:25 am
If either the monobasic cathepsin site or the polybasic furin site is adequate, is there a difference in strength between the two? I get the sense that the furin cleavage Is dominant because it leads to greater membrane-cell fusion and thus greater virulence. It’s hard to see what purpose cathepsin serves.
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Nerd has power
7/30/2020 08:39:00 am
I think, aside from the enzymatic activity, it also has something to do with how available each protease is in each type of cell and in each cellular location. Based on my understanding, furin is more ubiquitous, which adds to the cell tropism of the viral infection and likely facilitates S1 shedding by making the cutting happen at more than one cellular location.
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fuddman
7/31/2020 08:31:27 pm
Have you looked into why the GenBank Locus Name for 4991 changed from KP876546 to KP 876546.1?
Nerd has power
8/3/2020 09:27:57 am
Such an ID change at GenBank usually means an update has been done on the entry. However, I don't know what exactly was updated for 4991 in KP876546.1.
fuddman
8/3/2020 05:33:21 pm
"...GenBank [is] a scientific Wild West." Love that characterization and my gut feeling is - the characterization may be correct.
Nerd has power
8/4/2020 06:45:43 pm
4991 is RaTG13. I learned it fairly early on. Zhengli Shi most recently admitted it too in her email interview with Science. Yet she is still fumbling in explaining 1) why she made the name change (from 4991 to RaTG13) in her 2020 Nature paper without any description or explanation; 2) why she failed so miserably and did not cite her own 2016 publication where she first reported the RdRp sequence of 4991 (this short sequence is the only info published prior to COVID-19). Something is very filthy here and her recent interview did not make things any better for herself (actually she added another lie: she said that 4991 is the name for the bat sample, while RaTG13 is the name of the virus. Yet her 2016 paper clearly showed that 4991 referred to the virus, not the sample). 4991 and RaTG13 are the same and also not the same :). 8/3/2020 05:16:18 pm
Even though Furin is found within a cell's Golgi apparatus, I have read that it can preactivate cleavage before endocytosis takes place. Can some explain to me hoe this is possible and why a polybasic cleavage site is so much stronger than a monobasic one?
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John Ziggy Kelleher
8/3/2020 08:03:13 pm
Chinese Whistleblower, Dr. Li-Meng Yan Finally Dropped the Bombshells
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yano
8/3/2020 08:05:16 pm
"...GenBank [is] a scientific Wild West."
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yano
8/3/2020 08:22:10 pm
https://www.peakprosperity.com/forum-topic/scientific-history-of-ratg13/
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Greg Felton
8/4/2020 11:08:30 am
Has it been proven that the added furin cleavage siteS were PRRA?
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Greg Felton
8/5/2020 12:43:44 am
Let's change that question. I have seen PRRA as the added furin cleavage site amino acids but when I see the genomic analysis it is PRRAR with the RRAR as the tetra-acidic unit. Why is this?
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gsgs
8/5/2020 08:50:38 pm
SARS2 has ...ACTAATTCTCCTCGGCGGGCACGTAGT..
evidence
8/5/2020 05:34:50 pm
Re: SUMSKILZ blog (starting past June/2020)
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Brian
8/5/2020 06:46:12 pm
I am still thinking about page 39 of this WHO 2019 document.
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gsgs
8/5/2020 08:58:04 pm
https://apps.who.int/gpmb/assets/annual_report/GPMB_annualreport_2019.pdf
Xoco Latte
8/26/2020 03:11:24 am
Diversification planned ahead.
gsgs
8/5/2020 08:35:55 pm
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yano
8/6/2020 12:44:12 pm
@gsgs
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Brian
8/6/2020 06:34:05 pm
thanks gsgs that print it here...
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yano
8/7/2020 12:07:27 am
https://en.wikipedia.org/wiki/Exercise_Cygnus
Brian
8/7/2020 09:28:09 am
Yano
yano
8/7/2020 12:01:47 am
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Nerd has power
8/9/2020 06:39:08 am
There is no way that the R. affinis ACE2 would differ so drastically from those of other horseshoe bats and instead would resemble closely the human ACE2.
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Nerdshaveanswers?
8/7/2020 05:29:50 am
I am very late. I have some questions. There are so many animal markets in the world. Wouldn't such things happen more often in nature if the origin story is true?
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Nerd has power
8/9/2020 07:16:34 am
In fact, strictly speaking, there has been no credible evidence supporting the natural origin theory. Instead, the "evidence" used to support this theory are all showing their true nature -- products of fabrication (RaTG13, pangolin coronaviruses). This fact alone (if you believe it as much as I do) should suggest a bioweapon-nature of the virus. Why else would the Chinese communist government try so hard to spread misinformation and cover up the truth?
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Fuddman
8/9/2020 10:03:56 pm
I'm beginning to suspect the CCP/PLA is far ahead of everyone in developing, testing, releasing, concealing, monitoring and modifying a bio weapon.
Nerd has power
8/16/2020 06:03:16 pm
Very good points (that I almost missed). Like Dr. Li-Meng Yan said in a recent interview, when virologists make viruses, they never make just one. In addition, the CCP-controlled labs have been working on other deadly viruses, including ebola. The questions is for what??? If the world does not learn the lesson properly from SARS-CoV-2, I really think that it could be the end of things.
David Rivard
12/26/2020 10:58:41 am
I have an answer to your question about lethality. It is logical and cited by many others. Responses to more lethal diseases have always been swift and effective, no matter the up front costs or efforts.
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Robert Cartwright
8/9/2020 02:06:27 am
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Greg Felon
8/9/2020 07:19:00 pm
Dear Nerd: i have read polybasic cleavage sites make SARS-CoV-2 10-20 times more infectious than SARS-CoV, which only monobasic sites. Why is this the case? Why do double or triple arginines make SARS-CoV 2’s spike protein bind so much more efficiently?
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Nerd has power
8/13/2020 05:33:12 am
Hi Greg, the furin protease recognizes sequences with multiple basic residues clustered together. Without this polybasic feature, furin protease would not be able to recognize and cut that particular sequence.
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Greg Felton
8/13/2020 08:01:16 am
Yes, furin is ubiquitous, but how is furin cleavage more “efficient” than, say, monobasic cathepsin L cleavage? Is the Nature of the cleavage different? Also, your comment about multiple furin site inserts is most interesting. Can you elaborate or give a source?
Nerd has power
8/16/2020 05:48:31 pm
The insertion of furin-cleavage site most likely does not prevent other proteases from cutting at this site. Therefore, whatever the efficiency that SARS experiences in terms of proteolytic cleavage at this S1/S2 site, more is added to it for SARS-CoV-2 because you have added another player while having kept all the old players.
fuddman
8/14/2020 03:21:46 pm
This, so called, recent discovery may have an answer for you.
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David Rivard
8/13/2020 09:13:25 am
Are their any western clinicians working with Chinese counterparts? Where are their papers? One would think Mayo, Cleveland et al would be working with the high level Chinese counterparts. Would anyone know which clinical research sources could further educate the public in the U.S.?
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David Rivard
8/13/2020 10:16:41 am
Anyone out there have a list of retracted publications or "disappeared" clinicians that theorized genetically altered insertions in the genome? Lastly, the doctors who were the first responders who were allegedly clamped down by the government?
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Pete Ross
8/17/2020 01:28:56 am
Transmission Rate Studies And Not Vaccine Experiments Are the National Priority
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Pete Ross
8/17/2020 03:31:35 pm
The prospect of additional viral "escapes" and "more virulent mutations" belong to the analysis?
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Markus
8/17/2020 07:21:45 pm
China presently has a lot of people in concentration camps, who are subjected to many horrible things. Including,forced sterilization and medical experimentation. it may be that they were used as intermediate hosts.
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WSJ
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fuddman
8/21/2020 12:58:43 pm
The head of the NIH, Francis Collins, endorsed defunding EcoHealth Alliance
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Greg Felton
8/21/2020 01:07:50 pm
Fascinating development! Can you post a link?
fuddman
8/21/2020 01:47:57 pm
https://pulitzercenter.org/reporting/nih-imposes-outrageous-conditions-resuming-coronavirus-grant-targeted-trump
gsgs
8/20/2020 09:17:09 pm
can we have MN312632-5,71 ? The next closest ones.
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yano
8/21/2020 07:52:58 pm
https://nerdhaspower.weebly.com/uploads/1/3/1/2/131243129/syn-nonsyn-analysis_orig.png
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Nerd has power
8/24/2020 07:06:53 am
Good catch! As I have explained in the article, Shi intentionally made many changes (non-synonymous mutations) in the RBD region, which is roughly the 400-500 range of codons. This is because they knew that people will look at this region very carefully and, if the RBD of RaTG13 looks too similar to that of SARS-CoV-2, it would mean that RaTG13 could infect humans as efficiently as SARS-CoV-2. Remember, one thing the WIV strives to do is to deny the lab leak possibility. So, having a virus (RaTG13) that could infect humans as efficiently as SARS-CoV-2 would make it super hard for them to shed off the lab leak accusation. That's why they edited this region so heavily, resulting in an exponential rise of the curve.
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yano
8/24/2020 07:56:38 pm
The codon area from 500 to 1100 with no non-syn changes would suggest very heavy natural selection not to change. Suggesting that this area was very important to this viruses survival. After all, distant virus relatives are exactly the same, right?
Xoco Latte
8/26/2020 05:20:23 am
Another freshly published review on the origin of SC2 with a strong support for the alternative Null hypothesis that SC2 has a lab origin.
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Xoco Latte
8/26/2020 12:39:28 pm
I stand corrected for my earlier post here (I cannot refer to an actual post, so I have to quote it):
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Greg Felton
8/26/2020 01:14:42 pm
Indeed, this is odd, especially since a good case can be made that RaTG13 is 100% fictitious and that Shi Zhengli and Peter Daszak both admit that it the same sample as Bt-CoV/4991. Is it your contention that RaTG13 is real?
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Nerd has power
8/26/2020 06:16:11 pm
Yes, the twitter group has done an excellent job revealing the "bronchoalveolar lavage fluid" --> "fecal swab" change. Shi would tell everybody that it was just a correction of a careless mistake. But everyone with a brain and aware of the rest of the abnormalities surrounding RaTG13 would see this as another clear sign of fabrication.
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Greg Felton
8/26/2020 06:30:49 pm
Thanks, Nerd:
Xoco Latte
8/27/2020 05:00:02 am
Well, in my non-malicious interpretation, it might have been due to some human error based on ignorance or hectic stupidity.
Xoco Latte
8/27/2020 05:14:23 am
The Reply button sporadically is missing from the posts, so I have to use this method, for I am indeed sorry.
Nerd has power
8/29/2020 07:35:38 am
The bronchialalveolar lavage thing is interesting. However, it is the least in convincing me about the fabrication of RaTG13. There is abundance of substantial evidence, some of which I have summarized in my article. You may also check out this new preprint:
Greg Felton
8/29/2020 02:59:59 pm
Hi Nerd:
yano
8/27/2020 02:15:07 pm
Great interview! They mentioned the nerds.
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Nerd has power
8/29/2020 06:56:30 am
Great interview! Although I can't agree with Dr. Latham on some details (given how radical I am on this topic), It is nice to hear his confidence in a lab origin of SARS-CoV-2. Thanks for sharing it!
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yano
8/27/2020 08:47:21 pm
https://www.sciencemag.org/sites/default/files/Shi%20Zhengli%20Q&A.pdf
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Xoco Latte
8/28/2020 01:48:15 am
How a nice and smart answer! A virus lab chief who is accustomed to virus identification molbio methods by heart would supposedly trust clinical infection diagnostics based on serum antibodies against a novel human pathogen. At least she should have been shown some self-esteem and lie about the clinical diagnostic method having been used...
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Arnaud
8/28/2020 03:34:25 am
Hello,
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Xoco Latte
8/28/2020 06:27:50 am
Well, even the Chinese created a more compelling story behind the ID-change. A collusion of a 4-digit number with a completely unique alphabetical beginning like 'RaBtCoV/' as a viral strain ID vs. a serial number of an image inside an INSERM photo database...
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Arnaud
8/28/2020 08:19:31 am
This is not a nice try. Everybody is looking for a complex explanation. Inserm was very active in the creation of the wuhan lab, the database is quite old. using this number was an easy way to identify a vih vaccin study. Yves Levy 'ex Inserm boss) is very trouble man ans his wife was health minister in France until feb 2020. All that is to much for a random coincidence. I think all government are aware but also implicated in these researches, which justify the worldwide panic, even now, at the end of the epidemy.
Nerd has power
8/29/2020 07:04:36 am
Thanks for sharing. I don't know what to make of it though. I tend to think of this as a coincidence, but I understand how you may think differently.
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Arnaud
8/29/2020 08:55:01 am
Thanks for replying. I was convinced for months of a link between the number 4991 and Vih. All what I found could be coincidence, until this yesterday. I don't understand why i did not find it earlier. So simple : Google 4991 + VIH , second result... And when i shake Inserm, Yves levy, Wuhan, Ratg13, renaming, suspicious Vih inserts , world panic etc... I can't see just a coincidence.
annette
8/28/2020 05:13:02 am
Regarding the discussion, does anyone have information to say if a lab created synthetic virus will challenge the immune system in the same way as the natural virus and leave a person with long term immunity or will they become chronic with an auto immune disease?
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Nerd has power
8/29/2020 07:23:39 am
From what I see, I tend to believe that both are possible. A synthetic virus is still a virus. It would still challenge the immune system, which should lead to certain immunity and protection. The question, however, is how long the immunity would last. There have been multiple cases of people getting infected with SARS-CoV-2 twice within months. It was also shown that the antibodies resulted from natural infection wane away fairly quickly. These two observations are consistent with each other.
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Xoco Latte
8/28/2020 05:26:03 am
A freshly available preprint at BioRxiv nicely overviews sequence data and mutations of ORF8 from CoV-2 with comparisons to CoV-1, RaTG13 and a few other bat CoVs, as well as pangolin CoVs.
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reply bryan
8/29/2020 01:47:11 pm
I hope NerdhasPower can answer the reply from bryan quote:
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yano
8/29/2020 03:44:06 pm
Wondering the dame thing. How are other natural viruses mutation ratios. Found this doing some looking.
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Nerd has power
8/29/2020 09:45:59 pm
Sorry that I have missed this message from Brian. Lately I did not try to roll back and look at older posts. I apologize. I hope he still checks back and will be able to see my reply.
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Greg Felton
8/29/2020 10:39:53 pm
Thanks, CCP is Nazi, but I don't see anything new about Elannor Allens in those Chinese sites. I want to see her personal research, the one Nerd mentioned, about the statistical improbability of the syn/non-syn ratio. Is there anywhere else I could look?
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Nerd has power
9/3/2020 02:33:31 am
Here:
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Xoco Latte
8/31/2020 05:08:10 am
I would wonder, why to make such an orbital mistake of admitting that the lab - which presumably had isolated and sequenced this RaTG13 bat coronavirus - has no longer possesses any samples of the virus? Since it is relatively easy to synthetically produce it, although it has been too short time to do that from end of December to end of January... Still it seems to me as a non-professional mistake. Which, obviously, does not make this whole mess less stinking.
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Xoco Latte
8/31/2020 05:48:34 am
... of course, the above mentioned "mistake" is only valid if (and that is a huge IF) the sequence of RaTG13 would result in a 'viable' CoV that could be inoculate to cell cultures...
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Nerd has power
8/31/2020 03:31:19 pm
One possibility is that they are afraid that the RaTG13 virus may not be able to infect anything, including horseshoe bats. If the virus physically exists (through lab creation) and people request it from the Shi lab, they would look bad for not sharing it. Yet, sharing it would mean that somebody could immediately mix it with bat cells or cells carrying bat ACE2. The myth of RaTG13 would collapse immediately.
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Blast
9/1/2020 02:22:21 am
I would not be surprised that a right-winged administration could finance such a project, and indeed it would be a quite eye-opening one. If the RaTG13 has a fake sequence it might very well not function at all, and that would be a valuable data...If you want to declare war to China.
Nerd has power
9/2/2020 02:17:48 pm
Here is one possibility. Someone intentionally set your house on fire. Yet, you think it could just be an accident. Things happen. Let's move on. Whoever (including the police) think that this was done intentionally is simply over-reacting.
fuddman
9/2/2020 08:39:30 pm
Please refrain from using the term "nobody scientist" when referring to yourself.
Nerd has power
9/3/2020 02:54:32 am
:D Thank you! Somebody has to look into it. I don't think it's a hard scientific question. The big figures are silent, unfortunately. If they had reacted properly and responsibly, the world would suffer a lot less.
Annette
8/31/2020 06:02:13 pm
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Xoco Latte
9/2/2020 01:31:49 am
This is quite old news... The Australian drug company submitted an FDA clearence for clinical study in May, followed by a similar action in Europe in June.
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Under The Radar
9/2/2020 12:27:45 am
"SARS-CoV-2 RBD [receptor binding domain] bound human, pangolin, and horseshoe bat (R. macrotis) ACE2 more efficiently than the SARS-CoV-1 or RaTG13 RBD."
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Xoco Latte
9/2/2020 01:48:56 am
This latter preprint is truly striking... It suggests that the preexisting variant of SARS-CoV-2 has been relatively long adapted to human cells BEFORE gaining the PRRA furin cleavage site insert. Only a hypothesis, but if valid, strongly undermines the serendipitous, natural bat-to-human spillover narrative.
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evidence
9/19/2020 05:42:55 am
RE: PRRA insertion likely being the last GOF manipulation step, in particular after RBD adaptation
Pete Ross
9/3/2020 03:54:20 pm
Some questions about BW's that may or may not pertain to the current situation:
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9/6/2020 12:20:02 pm
Political correctness does not work in science. Wumao/50 cent army or
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yano
9/6/2020 01:54:05 pm
That's great! Looks like they are just pointing out how unique SARS COV 2 is and that it was pre adapted to humans. We need more scientist pointing this out.
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Interested One
9/6/2020 04:06:08 pm
We took the questions out, as we wanted to get the paper published in a major journal. Shouldn't that be obvious?
Interested ONe
9/6/2020 04:10:53 pm
Where are the recombinant live attenuated coronavirus vaccines, I think you are asking?
Nerd has power
9/9/2020 09:11:00 pm
Hi Interested One, are you one of the authors of this peer-reviewed JMV article? It's a wonderful piece! Now nobody can say that "no peer reviewed articles support a lab origin of SARS-CoV-2". I can tell how you have to tailor your words just so that you pass peer review. It's not easy. Thank you for doing it and congrats on this milestone publication!
Greg Felton
9/6/2020 02:01:09 pm
Hi Nerd:
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Nerd has power
9/9/2020 08:58:51 pm
Sequencing of these viral RNAs is done by first converting them into the corresponding DNAs. That's why you see the sequences of SARS-CoV-2 strains on GenBank all have ATGC not AUGC. Basically, if you have settled down on a sequence, you can write it in two different ways (T vs. U) and yet they mean the same thing.
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Greg Feltron
9/9/2020 09:20:28 pm
Thank you for clarifying that. The journal article you cited is an encouraging sign that perhaps real debate on the synthetic nature of SARS-CoV-2 is possible.
Interested One
9/13/2020 05:15:39 am
Nerd
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Xoco Latte
9/7/2020 03:51:18 am
I am certainly ignorant or overlooked some details but would you please point me to what you refer to that presumably happened the October 6th of last year?
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Interested One
9/8/2020 06:40:26 pm
Cellphone mobility records show a severe decline around the WIV from 10/6/19 to 10/13/19 consistent with some event.
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evidence
9/12/2020 07:30:01 am
Alex
9/8/2020 02:46:59 am
What technology would they have used, crispr?
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Alex
9/9/2020 11:37:33 pm
anyone have ideas about these questions?
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Interested One
9/10/2020 06:19:56 pm
No need to use CRISPR. Nothing that fancy. Simple ligation of pieces of virus cDNA, some of them mutant through PCR mutagenesis, into a 30,000 bp cDNA construct. The construct is then either propagated as an artificial chromosome in bacteria or yeast, and then purfied and transfected into human cells permissive to the virus. The virus is then made from RNA transcription of the cDNA clone in these cells and secreted.
Alex
9/11/2020 06:36:35 am
Merci, Interested One.
The Philosopher
10/14/2020 06:26:36 am
@Alex
alex
10/14/2020 08:31:39 am
I agree with the statement that the Chinese Government is lying. But does the Chinese government also lie with the Hong Kong figures? I find it a bit more difficult to hide a high incidence in Hong Kong than in the rest of Mainland China. And in Hong Kong the mortality caused by the virus is also very low according to official figures. 9/8/2020 11:32:42 am
Of course, this could not be geo-politically related, with a release date just before the U.S. elections.
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yano
9/8/2020 07:32:08 pm
https://youtu.be/ep9GxRFK3rk
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M-Z-1-2-3-4
9/13/2020 09:04:08 pm
Could COVID-19 Have Escaped from a Lab? -- 9/9/2020
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9/13/2020 09:14:25 pm
The truth will soon be uncovered - Dr. Li-Meng Yan (Virologist from Hong Kong) joins this week’s edition of Uncovering the Truth to discuss the origins of coronavirus and the Wuhan lab at the center of it all.
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J
9/14/2020 08:47:38 am
This is the paper she just released:
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yano
9/14/2020 10:55:47 am
Great! Excellent paper!
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Xoco Latte
9/15/2020 07:42:58 am
Huh, that is a very focused, highly detailed piece of a manuscript!
Xoco Latte
9/15/2020 08:04:59 am
I try to refine my above opinion to some extent.
Yi Wang
9/14/2020 09:08:11 pm
Thanks for your sharing! The world becomes great because of you guys!
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CCP is NAZI
9/15/2020 08:25:19 am
Those who call unleashing CCP virus as an "accidental" outbreak need to explain if letting Wuhan people out to spread virus everywhere in the world but not within China is accidental, buying all the PPE all over the world back to China is accidental, preventing 3M from exporting their own masks back to U.S. is accidental, refusing to open their P4 lab to the worldwide virologists is accidental, destroying their virus sequence data is accidental, hacking/hindering other countries' vaccine development is accidental Naive? Foolish? Or simply evil???
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Xoco Latte
9/15/2020 09:14:12 am
Each "evidence" you listed as solid "proofs" for a purportedly deliberate unleashing the "CCP" virus onto the rest of the world but not China, are IMHO just consequential and as such, logical, actions after an accidental breakout of a still-work-in-progress viral construct.
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Xoco Latte
9/15/2020 09:17:00 am
Correction (eh):
CCP is NAZI
9/15/2020 10:13:35 am
CCP would surely love the whole world to be just like you so that they can unleash the next batch of virus to achieve their world domination dream and realize their NAZI goal. Make sure to come back and
Greg Felton
9/15/2020 11:16:25 am
Intend to agree. Militating against deliberate release is the lack of a credible cover story. The CCP, Shi Zhengli et al. have made utter asses of themselves trying to pass off the Huanan market as the source of the pandemic and pass off the fabricated RaTG13 as the progenitor of SARS-CoV-2. These are signs of desperate and incompetent improvisation.
CCP is NAZI
9/15/2020 11:30:29 am
What you are saying is like asking for the evidence destroyed by the criminal. No problem, Dr. Yan has more to disclose. Further, the evidence is well kept in Wuhan P4 lab.The quickest and easiest way is to simply open their lab to the world, you will find plenty of evidence. good luck!
CCP is NAZI
9/15/2020 01:10:03 pm
Wow, just when I said Dr. Yan has more to disclose, her twitter account is suspended. See how scared Nazi CCP are? They cannot even defend themselves or stand out to argue with her, but just use their power to suspend her account. Don't worry, for anyone who are truly interested to find out the truth, simply contact her at [email protected]. Otherwise, don't even bother, as threat does not work in science!
CCP is NAZI
9/15/2020 07:51:38 pm
Watch Fox news, https://www.youtube.com/watch?v=qFlqXPl_hZQ, to see the witness, Dr. Yan, firmly stated that CCP virus is unleashed purposely. Those "naive" people need to stop being "naive". More to come in her second paper.
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yano
9/15/2020 08:35:39 pm
I watched it. It's great she is standing up and telling the truth.
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Greg Felton
9/15/2020 08:47:13 pm
Outstanding post. I concur: intentional release seems implausible, notwithstanding what Yan Mengli has said. However, there may be an answer, and it is analogous to the Sarin gas attack that took place in Damascus in August 2013. Saudi Arabia, Turkey and the U.S. were staging a false-flag chemical attack that would be blamed on Syrian president Bashar al-Assad and justify U.S. invasion. However, the dirty bomb went off prematurely in the neighbourhood of Ghouta. There was malicious intent, but the timing was off.
CCP is NAZI
9/15/2020 09:00:27 pm
Indeed a great video. Ex-Chinese Official's Plan for World Domination should answer all your questions: 9/15/2020 11:46:14 pm
Thanks for your work. I read your paper pretty carefully but not (so far) many comments. Apologies if my question (to follow) has been answered. I am impressed by your logic (though note the tone at times will put many off). I checked several of your references and found no problems. I wondered however, about your statement that Prof Shi's lab allegedly collected some bat feces about 7 years ago and analyzed these samples for possible presence of coronaviruses based on genetic evidence. I looked at the paper you cite and could not find evidence for this. Is it just based on your informants? If so it's not sufficiently convincing.
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Nerd has power
9/17/2020 05:15:14 pm
Thank you for the comments. To answer your question, the virus that was collected 7 years ago was named RaBtCoV/4991. It was first published in 2016:
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Ted
9/16/2020 10:12:16 am
Thanks again for your work.
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Aihar Tol
9/16/2020 03:19:54 pm
This “Ted” sounds like the usual Wumao apparatchik trying to lead everyone away from what the CCP considers dangerous territory. I expect Yan Meng Li’s assertions to eventually converge with Nerdhaspower’s arguments, and the hurry to exclude her probably shows the CCP is really worried about this.
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Greg Felton
9/16/2020 03:27:47 pm
Aihar tol, you are out of line. Ted's post was rational and intelligent. There is nothing wrong with holding Yan Mengli accountable for what she says. Your attack on Ted is ad hominem and typical of an apparatchik that wants to silence debate by deflecting attention from the substance of the argument.
Aihar Tol
9/16/2020 06:14:11 pm
Greg Felton
Greg Fellton
9/16/2020 06:22:59 pm
Aihar Tol:
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Aihar Tol
9/16/2020 06:53:45 pm
Greg Felton (Wumao, HQ)
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Greg Felton
9/16/2020 07:01:29 pm
Dear Nerd:
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Aihar Tol
9/16/2020 09:49:40 pm
Not to belabor the obvious, pointing out standard Wumao techniques does not make me an acolyte of the vastly brave Yan Menli.
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CCP is NAZI
9/16/2020 07:53:24 pm
For those who insist to exclude bio-weapon assertions, please read
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Greg Felton
9/16/2020 08:20:32 pm
CCP is NAZI:
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CCP is NAZI
9/16/2020 08:45:48 pm
Greg Felton,
Greg Felton
9/16/2020 09:11:22 pm
CCP is NAZI:
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Greg Felton
9/16/2020 09:16:09 pm
Let me rephrase: “Should the abusive treatment of Ted be defended because he does not uncritically believe everything Yan Mengli says?
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CCP is NAZI
9/16/2020 09:34:31 pm
"Abusive" sounds a strong word. But if you considered what ted gets is abusive, then his demanding others to rewrite without incorporating bio-weapon is abusive as well which is like ordering others to look positively at the CCP while ignoring their secret three-year deal to expand potential bio-warfare capabilities
Ahai Tol
9/16/2020 09:42:20 pm
Greg Felton
CCP is NAZI
9/16/2020 09:19:12 pm
It's interesting that ted himself does not stand out to confront me but you instead. Why does he demand others to rewrite without incorporating bio-weapon? Like what I said previously: Unless you can show the evidence that this secret three-year deal to expand potential bio-warfare capabilities is non existent or have the ability to show Wuhan P4 lab to the world to prove that they are not developing biowar weapons, you have absolutely NO right to demand others to analyze CCP virus in your ways.
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Aihar Tol
9/16/2020 09:36:06 pm
That’s standard Wumao SOP to make the casual observer think that Ted is a real victim and some gallant knight is defending him, when in reality they’re in cahoots with each other, reading off the same talking points, trying to misdirect everyone to the same direction.
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Greg Felton
9/16/2020 09:43:10 pm
You’re hysterical, dishonest and ridiculous. I made NO SUCH DEMAND. I am not even talking about the CCP. YOU are. What I object to is your refusal to address a comment in a respectful, intelligent manner. You are apparently incapable of that. Also, how do you prove someone ISN’T doing something?? If you are so sure the Wuhan lab was making a bioweapon, then back up your allegation. All you’re doing is making your claim (and Yan’s) look emotional. I think I’ll include you in my book.
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CCP is NAZI
9/16/2020 09:53:45 pm
The one who say others are hysterical, dishonest and ridiculous are just like that themselves. Many like you already asked Nerd has powers not to analyze CCP virus in terms of bioweapons and s/he already explained why s/he did. Did you simply not bother to read through or you just want to ignore it? If you want others to respect you, you need to first respect others. Don't waste everyone's time!
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Ahai Tol
9/16/2020 09:58:54 pm
Yawn: standard Wumao self righteous victimism.
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Greg Felton
9/16/2020 11:14:30 pm
Who the fuck do you think you are! You and your lapdog CCP is NAZi are devoid of even the most basic intelligence. You hurl ad hominem clichés like Wumao to avoid having to act like an adult. I don't give a fuck what you or anyone else thinks. Your infantile behaviour and incapacity for honest discourse should get you banned from this thread:
CCP is NAZI
9/16/2020 11:54:55 pm
Lol, lapdog? You yourself seem more like a CCP's lapdog. If things don't get your way, then a full mouth of f words which exactly shows your true nature rather than a scholar who does not even bother to go through the original purpose of this article and want everyone to only look at CCP virus in your direction but not any other directions. Nerd has power: would you condone Greg Felton's mouthful f words and insulting behavior?
CCP is NAZI
9/16/2020 10:03:09 pm
If the CCP have nothing to hide, why have they been persistently refusing Trump's persistent offer with a team of top scientists to control CCP virus? Ya, lock up the evidence to ask others to find the evidence. What a joke! Simply open up the lab to shut everyone up!
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Ahai Tol
9/17/2020 03:57:35 am
If the CCP had nothing to hide then why all these elaborate ruse to try to discover Nerd’s real identity? Why all these elaborate efforts to prevent any discussion of Ms. Yan’s points? All these elaborate tag teaming to misdirect everyone in this group away from certain avenues of discussion ....?
yano
9/16/2020 10:01:12 pm
I went back and read Nerd's paper and looked through reference 6.
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Grerg Felteon
9/17/2020 12:04:33 am
You raise some valid points. The question of a bioweapon so far is all theory. It is regrettable that febrile children like CCP is NAZI (The name pretty much gives him away) are incapable of rational discourse on the matter and resort to name-calling.
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CCP is NAZI
9/17/2020 08:18:10 am
Grerg Felteon: What's wrong with using "CCP is NAZI" which is a proven fact? Those who disagree that CCP is NAZI are grounded to be nazi themselves as well and need CCP to get their organs live harvested to profoundly accept the fact.
CCP is NAZI
9/17/2020 08:32:39 am
What was published is already published and they cannot withdraw it or delete it like what they did to Patient Zero's profile and Dr. Yan's profile on their official P4 lab site. Had CCP known that the world would question about Huang Yanling as Patient Zero and that Dr. Yan fled to tell the world the truth, do you think their profiles would still be on their websites? CCP probably never image that they had to unleash the bioweapon so soon instead of waiting for the more mature versions to be developed for no one to get a trace of it.
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yano
9/17/2020 12:16:53 pm
"what if CCP originally didn't plan to release the bioweapon?"
Greg Felton
9/19/2020 12:37:57 am
Yano: Please explain to me what restriction sites do and how they are created.
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하얀 왕관 참새 - PhD
9/20/2020 06:54:31 pm
Damn, Greg, just google it. Its basic genetics!
하얀 왕관 참새 - PhD
9/20/2020 07:29:32 pm
Another hack, Andersen was quoted as saying this, on evidence:
Greg Felton
9/17/2020 12:12:59 am
CCP is NAZI:
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Xoco Latte
9/17/2020 03:13:38 am
Uff, WTF is going on here?
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Greg Felton
9/17/2020 03:23:33 am
I agree Xoco Latte, and I am sorry it came to that. If you want to point fingers look to Ahai Tol and CCP is NAZI. I came to the defence of one poster (Ted), who raised some interesting questions about Yan Mengli's accusations. I can't speak to them--at least not yet-- but I respected Ted's skepticism and resented Ahai Tol's ad hominem attack on him. For my efforts I was insulted as a Wumao troll and a CCP agent. I regret that my frustration with these two yahoos got the better of me. I hope this is the last we hear from them.
Ahai Tol
9/17/2020 03:45:07 am
Add another Wumao, make it look organic rather than the team effort that it is.
CCP is NAZI
9/17/2020 08:52:19 am
Ahai To: add another Wumao? Who knows? Maybe it's the same Wumao, just changed the name. Even "Nerd has power" cannot tell if the same Wumao changed not only his name but also his email address when posting. You never know. Haha...
Ahai Tol
9/17/2020 03:50:09 am
The CCP’s paid hacks are all out attacking Yan Mengli in this forum. Brave Ms. Yan must have really hit a CCP nerve. The CCP is now making it difficult for relevant medical and research personnel from defecting to the West. The CCP’s head is exploding, all thanks to brave Ms. Yan.
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CCP is NAZI
9/17/2020 08:45:19 am
Reading through your posts,I don't see you have contributed more to this blog than I. So, no need to point fingers around before checking yourself first. All I see is that you are dragging Nerd has power's time to answer this or that question. Even I answered one of your questions. No need to ask Nerd has power to rewrite his or her essay in your specific direction or a politically correct way. Simply start with yourself. Aren't you claiming that you are writing a book?
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Greg Felton
9/17/2020 03:50:15 am
Ahai tol, you are a pathetic, hostile broken record. You have nothing to say and you keep saying it.
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Ahai Tol
9/17/2020 04:03:40 am
Well I implore Nerd to keep me on as I am actually following the science. I just don’t want CCP apparatchiks censoring what we’re discussing here so that it adheres to the CCP’s talking points, as it is very obvious that Nerd started this project with the expectation that the CCP will come hard after him and trying to misdirect the thrust of his research and analysis.
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Greg Felton
9/17/2020 01:05:29 pm
You have shown no interest in science and are preoccupied with defaming me because I do not worship Yan Mengli. I have asked Nerd to remove you because nobody should be subjected to abuse. You have no idea who I am and have NO RIGHT to call me a CCP apparatchik.
CCP is NAZI
9/17/2020 02:43:47 pm
For those who understand the science? Lol, science has so many areas such as virology, biology, medicine, chemistry, physics, computer science, astronomy and many more. Those who claim themselves know science and assume others don't are ignorant and narcissistic. A biased or narrow minded scientist in his field is no better than someone who is not in the same field but has strong analytical reasoning and research skills.
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Greg Felton
9/17/2020 02:48:45 pm
I couldn't care less what you think. I am addressing those on this site that have the intelligence and maturity to discuss the science of SARS-CoV-2 .That disqualifies you since all you can do is insult and throw tantrums.
CCP is NAZI
9/17/2020 03:02:00 pm
You are just as disqualified by asking others to rewrite without incorporating bio-weapons when more and more witness of Chinese bioweapons have emerged. No need to ask Nerd has power to rewrite his or her essay in your specific direction or a politically correct way. You have all your right to write your own, but you have no right to ask others to write something in your way. Simply start from yourself. Aren't you claiming that you are writing a book? Does your book even have a chapter? Why don't you publish yours and post a link here to let everyone here comment on?
Ahai Tol
9/17/2020 06:18:55 pm
Says the person who insults other people and throw tantrums because he can’t make everyone rewrite their analysis to agree with his CCP talking points ..... ?
Ahai Tol
9/17/2020 06:22:03 pm
Well said. If I understand this article, the absence of mutation is the tell-tale sign of anthropic meddling, though some of the earliest comments on this thread suggest the opposite is evidence of Covid's lab origin? - https://www.bostonmagazine.com/news/2020/09/09/alina-chan-broad-institute-coronavirus/
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CCP is NAZI
9/17/2020 02:48:45 pm
Didn't we just talk about Chinese bioweapons? There comes another witness other than Dr. Yan. Let's see what he has to say:
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Greg Felton
9/17/2020 03:08:28 pm
CCP is NAZI: *Yawn* [Communication terminated]
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Greg Felton
9/17/2020 03:10:14 pm
Can anyone address the claim that ZC45 is the backbone for SARS-CoV-2?
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Bemused101
9/17/2020 03:28:13 pm
Most of the scientific discussion on this blog is way beyond me. However, I am enjoying trying to get my ahead around at least the key concepts. Some of the recent comments have provided some comedy relief! It is hilarious watching some of the bloggers here jump to conclusions. One blogger makes a polite suggestion. Then others pile in suggesting that the blogger and defenders of the blogger are pro-CCP. I get that we are in heightened times of paranoia. But really.
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Greg Felton
9/17/2020 03:32:26 pm
Hi Bemused 101: Good to hear from you. I am glad that someone has picked up on the petulant conduct of those two bloggers, who shall remain nameless. I, too, am learning about the epidemiology behind SARS-CoV-2 and find the SCIENTIFIC discussions on this site most helpful.
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Bemused101
9/17/2020 04:56:32 pm
Hi Greg- one must keep things civil and polite at all times. I understand where some of these bloggers are coming from/relating to how the CCP operates. However- they never faced my mother (RIP) and he rules when it came to (lack of) politeness and manners. Fearsome!!
Ahai Tol
9/17/2020 06:10:17 pm
Another Wumao team mate inducted in to create the fiction that there is organic agreement around the talking points being pushed by the CCP propaganda arm ..... as well as an excuse to censor talking points not in agreement with the CCP. Even your email templates are the same ....
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CCP is NAZI
9/17/2020 03:49:18 pm
It looks like if a conversation is in someone's interest, even if it's off topic, it's still fine. But if it's against his interest, he will then demand others get back on topic. How hypocritical!
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CCP is NAZI
9/17/2020 04:32:42 pm
A polite suggestion with an impolite intention is just as impolite. The author has already presented his/her reasoning and argument. Now s/he is asked to rewrite a CCP friendly one for a book that probably does not even have a chapter. When asking that person to write his own and post a link of his own book or even a single page, then nothing is heard.
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Ahai Tol
9/17/2020 04:49:52 pm
Amen.
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Bemused101
9/17/2020 04:50:11 pm
Hello CCP is Nazi. I don't understand how the original polite post from TED can be seen as CCP friendly. I thought the CCP were unfriendly to any suggestion that this virus wasn't of zoonotic origin. One wonders if the "milk before meat" adage applies here. That is: placing so much emphasis on the bioweapon argument is too hard for most people to digest and is therefore quickly discarded. And the more digestible bites of information around GoF, lab leaks etc are also discarded.
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Bemused101
9/17/2020 05:12:48 pm
Correction: That the more digestible bites (GoF) lab leaks may not be so quickly discarded.
CCP is NAZI
9/17/2020 06:56:17 pm
Bemused101:
David Rivard
9/17/2020 06:26:03 pm
There are few discourses where a non-scientist, like me, can participate in a scientific discussion about this historic event which we are all a part of. This site makes me feel like I am a part of the story taking shape. “ I'm just an Ironworker and I can still figure this stuff out". As this virus reminds us, we are all the same species and whatever intellectual or physical advantages we individually think we have over one another the differences are so slight that, with equal training, we are lucky to trim off a minute over the distance of a marathon. In reality, there are probably well over 25% of the 7.8 billion people on the planet that see what I see. That's almost 2 billion people! Even if I'm half wrong, there are almost a billion of us.
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Ahai Tol
9/17/2020 07:07:53 pm
Totally agree with this: All we want is to participate in and learn from open scientific discussions without fear of being censored by government-funded apparatchiks that want to misdirect us to different directions that are convenient for a certain government.
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Greg Felton
9/17/2020 07:19:24 pm
So, how long will my posts be held up, Nerd? I am not the one who started this, and I have been treated sith conspicuous disrespect. I am genuinely interested in your response to my question about ZC45 and SARS-CoV-2.
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Ahai Tol
9/17/2020 07:53:42 pm
Respect is earned, not demanded while throwing tantrums.
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Mr.Trololo
9/18/2020 03:16:37 pm
Excuse me, Nerd has power, are you this one?
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Virus Hunter
9/18/2020 04:28:10 pm
I honestly dont find any of your arguments convincing. Your claims about improbability of natural evolution are pure speculation. You just cannot ignore the fact that many Sarbecoviruses still remain undiscovered (closer relatives etc.) and that its not so easy to find them in the first place (we have only scratched the surface). Next, Im fully aware that the CCP is capable of something like this and that it could serve them well but thats not evidence. Do you really think the CCP would use Shi Zhengli to create SARS-CoV-2? She is arguably the most famous coronavirus expert in the entire world and has also conducted gain of function research. There are likely other less known scientists capable of this. If their intention was to hide the truth...why Shi? Shi would be the first suspect by default. Now lets assume it wasnt Shi but rather someone else and lets assume its not an accident but intentional. If so...why in the freaking universe would they release it in Wuhan??? Im sure there are even better locations to start the epidemic if your goal is to spread the virus worldwide quickly. Why do it in the city that harbors the workplace of Shi Zhengli? Also isnt it reasonable to assume that something like this should have been planned for awhile? If so why not fabricate and publish the RaTG13 genome in advance instead?A reactionary publication only raises suspicion. I dont really find the "missing RaTG13 samples" suspicous either. Now correct me if Im wrong, but Shi has been identifying viruses by sequencing a short fragment in their RdRp region and only taking interest in the ones closely related to SARS-CoV. Those are the ones she used to sequence and keep as physical samples for further research. There was no reason for her to keep RaTG13 then. You said that its RBD sequence should have alarmed her but since she didnt sequence it back then it couldnt (again maybe my memory serves me wrong and I should have checked the paper again before commenting but I dont remember her presenting the RBD sequence). Back to Wuhan. Why would they claim there that SARS-CoV-2 was not found in animals at the Huanan Seafood Market? I imagine fabricating evidence of SARS-CoV-2 in an animal would have been the best thing to lie about (found in an animal from the market, just like SARS-CoV...excellent case closed!). Of course you could argue that their plan to cover their tracks was flawed but honestly...some of the flaws are so bad that it looks as if a brain-damaged person planned it out.
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yano
9/18/2020 05:08:34 pm
Exactly, a bunch of dummies running around messing things up.
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Virus Hunter
9/18/2020 06:18:08 pm
@yano
Greg Felton
9/18/2020 05:11:20 pm
Virus Hunter: Perhaps you could regale us with some definitive proof of natural origin instead of engaging in deflection and reciting cognitive denials. If you want proof that the natural-origin theory is untenable, I would be happy to send you a copy of my book when it comes out this fall.
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yano
9/18/2020 05:18:41 pm
Birger Sørensen:
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Greg Felton
9/18/2020 06:50:46 pm
Virus Hunter:
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Virus Hunter
9/18/2020 07:13:45 pm
"I have no problem asserting a lab origin because the genomic mutations in SARS-CoV-2 could not have come from nature."
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Greg Felton
9/18/2020 07:50:39 pm
Thanks for committing intellectual suicide by doing exactly what zoonotic apologists do. Nothing you say is remotely relates to SARS-CoV-2; all you have is whinging and non-responsive, historical (or is that, hysterical) boilerplate about the history of viruses. This attempt at argument is tautological because it implicitly assumes a zoonotic origin. In logic that is known As “The Genetic Fallacy.”
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Virus Hunter
9/18/2020 08:09:16 pm
Nothing in the comment section is anything close to solid conclusive evidence. Most of the arguments have been challenged with alternative explanations. Maybe you should scroll up again and reread them. I see you like logical fallacies - guess what, claiming that feature X of SARS-CoV-2 is suspicious because it doesnt exist in other KNOWN SARSr-CoVs or that feature Y couldnt have occurred just because you cannot think of an alternative is an ARGUMENT FROM IGNORANCE.
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Greg Felton
9/18/2020 08:33:02 pm
I accept your inability to argue rationally.
yano
9/18/2020 09:38:29 pm
"Nothing in the comment section is anything close to solid conclusive evidence."
Jenny
9/18/2020 10:02:40 pm
How do you explain that no other CoV which harbour a furin cleavage site use ACE2 receptor for cell entry? SARS-CoV-2 is really a wonder from nature, also considering the double CGG, never seen coding for that sequence. Just to remind you, the furin cleavage site is new in SARS-CoV-2 group. Sarbecovirus do not really need it, because they have at the same position another kind of cleavage site. Why should it then naturally evolve? This special sequence, which is conveniently creating a FauI restriction site, permits to track if the cleavage site is lost by cell passage. Because, beside human airway cell, this site seems to impede, more than help the virus for cell entry.
Xoco Latte
9/19/2020 02:51:58 am
Uh-uh... sorry: is this when clapping required? Congrats, this was really, truly groundbreaking, earth-shattering. Genius.
yano
9/18/2020 10:37:39 pm
What is the probability of a natural occurring virus having all of the features of SARS Cov 2?
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yano
9/19/2020 11:46:51 am
From John F Signus above
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Vasile
9/19/2020 08:33:51 pm
.Good point about Andersen's paper.
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Xoco Latte
9/20/2020 03:52:44 am
I unsuccessfully tried to find this paper here in the earlier comments:
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Xoco Latte
9/20/2020 04:18:35 am
With regards to the above referred paper, a take-home message is concluded by the author as this (most of the methods and figures are way beyond my abilities of comprehension, so I tend to accept his Conclusions):
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Babstar
9/20/2020 03:07:04 pm
I would wager a sizeable amount of cash, that this "bat" CoV/RaTG13 coronavirus would never have a real chance of infecting the proper cells, or for that matter, Rhinopulos bats. Ever.
하얀 왕관 참새 - PhD
9/20/2020 06:01:22 pm
@babstar some of this work has been done already and mentioned by nerdhaspower in the other article on this page and likely will appear in the 2nd Yan paper as well.
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하얀 왕관 참새 - PhD
9/20/2020 06:22:25 pm
@babstar
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yano
9/20/2020 06:29:06 pm
From the Nerd above:
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yano
9/20/2020 06:35:40 pm
The bat virus that does not bind to bats. lol.
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하얀 왕관 참새 - PhD
9/20/2020 07:13:39 pm
Yano: yeah the pangolin thing has been done for a while. The RBD differs from sars-cov-2 too much at the nucleotide level (the only level that matters) for it to be related.
Greg Felton
9/20/2020 07:22:32 pm
하얀 왕관 참새 - PhD:
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하얀 왕관 참새 - PhD
9/20/2020 07:33:35 pm
there's saying that i'm paraphrasing but it goes like
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Greg Felton
9/20/2020 07:38:39 pm
It is clear that you think very highly of yourself, and I am only to happy to bask in the munificence of your contributions.
Anonymous
9/20/2020 07:50:15 pm
Thank you for putting the so called Google-challenged book author in his/her proper place. It’s good to see it disabused of its notion that it has been positively contributing to this thread.
하얀 왕관 참새
9/20/2020 08:11:40 pm
Greg Felton
9/20/2020 10:54:31 pm
하얀 왕관 참새:
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The Philosopher
9/21/2020 12:09:29 am
Some more good tweets:
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The Philosopher
9/21/2020 12:34:45 am
Oops, here's the tweet for the above re: rmyn02
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yano
9/21/2020 06:26:52 pm
"Remember that, because the people the media chose to talk to originally said that a lab origin was impossible or that the techniques weren't available, or there needed to be a known backbone, so you'd be able to spot it, yadda yadda ('n o see um' technology papers must have not been on their radars?) Basically, all manner of excuses that were disingenuous as to the knowledge about what actually can be done in terms of research."
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Another Interested One
9/21/2020 04:26:21 am
To all: let us tone down the level of rhetoric where we need to and have a respectful debate. There is enough rancor outside of this forum for that. This is why people like me dislike social media so much and do not like to participate.
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The Philosopher
9/21/2020 08:27:15 am
@Another Interested One: " to try to make a live attenuated pan-coronavirus vaccine"
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yano
9/21/2020 08:42:12 am
Great post, but I'm going to have to add to 1) and 2) below.as the reasons for GOF research.
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Another Interested One
9/21/2020 12:06:29 pm
Did Shi or Baric publish papers about vaccines? Did their research further vaccine development science?
Another Interested One
9/21/2020 09:53:21 am
Were they making vaccines? Of course they were. Just none of them worked that well.
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The Philosopher
9/21/2020 10:16:33 am
Re nsp16: No, care to enlighten us? Also, that paper isn't explicitly about vaccines. It's also fairly dense. Maybe explain a bit?
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Another Interested One
9/21/2020 10:29:38 am
Sorry for the incorrect paper. That work is related to this vaccine paper.
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Xoco Latte
9/22/2020 12:37:13 am
Hmm, this is quite interesting paper by the Baric group, seemingly reporting an unsuccessful attempt at creating a SARS CoV-1 attenuated live vaccine, based on manipulation of SARS-CoV-1 Nsp16 in a mouse model as host:
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9/21/2020 12:49:04 pm
Not sure if it’s posted above, but in case anyone needs a peer reviewed source that argues for a lab release:
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David Rivard
9/21/2020 05:00:38 pm
More journalists jumping aboard:
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The Philosopher
9/21/2020 05:06:28 pm
"BioEssays is a monthly peer-reviewed review journal covering molecular and cellular biology. Areas covered include genetics, genomics, epigenetics, evolution, developmental biology, neuroscience, human biology, physiology, systems biology, and plant biology. The journal also publishes commentaries on aspects of science communication, education, policy, and current affairs"
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Andrew M
9/22/2020 02:04:16 am
A few minutes On Google reveals Dan is a political scientist and that the article was peer reviewed by his father. Also that Dan has an interesting personal history ("Daniel Mandel Serotkin" will get you there faster). Why is this relevant? It goes to trust as a source. Same with Dr Yan - Fox News and Steve Bannon do not inspire trust in her as a source. So you may say I should focus on her actual "research". It's very poor. What we here from her is more innuendo than science.
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The Philosopher
9/22/2020 03:09:33 am
You're labeling it as innuendo. Technically, it reads more like a review, which is a legitimate scientific writing format. Also many of the sources are more valid than the "proximal origin" letter (which is in fact a letter to the editor and NOT a peer-reviewed paper. look up what a "correspondence" is in Nature medicine...)
Interested One
9/22/2020 04:08:02 am
You have no idea who people like me are. If you did you may think a bit differently about these sorts of comments.
yano
9/22/2020 09:10:22 am
https://www.youtube.com/watch?v=sBQplOe8-LE
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CCP is NAZI
9/22/2020 09:31:34 pm
"In Virology, we know that just one virus never comes out during a project. Usually, there are a group of virus candidates...this is just the first type, and it has already triggered a historic pandemic," says Chinese virologist Dr Li-Meng Yan
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Carmelo
9/22/2020 09:48:52 pm
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The Philosopher
9/22/2020 10:21:24 pm
@Carmelo you're leaving out the juiciest bits. I'll translate from Italian (spineless- has no integrity to go on American news! Or American news are full of pro-CCP moneypushers and wouldn't want this out there)
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Xoco Latte
9/22/2020 11:55:10 pm
First of all, it is an old technique to put a big chunk of aversional/diversional piece into foreign media in foreign language, to serve an intended goal. This is no exemption either.
The Philosopher
9/23/2020 11:34:00 am
https://twitter.com/Alannah223/status/1308754171819106311
The Philosopher
9/23/2020 11:39:51 am
https://twitter.com/Alannah223
yano
9/22/2020 10:21:53 pm
Link from The Philosopher above:
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Xoco Latte
9/23/2020 12:18:08 am
I'm no expert therefore I might be off with this opinion.
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The Philosopher
9/23/2020 01:46:23 am
@xoco
Yes yes yes
9/23/2020 07:04:38 am
Spot on, Philosopher and Xoco.
The Philosopher
9/23/2020 11:55:16 am
https://twitter.com/Ayjchan/status/1308477880398155776
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David Rivard
9/23/2020 01:00:54 pm
Great comments Xoco. There are many links of Drs. Baric and Shi's research together as part of a team. In fact, there seems to be two scientific camps, the Shi team; teams of virologists working under “gain of function” grants (the haves), and a growing majority of virologists (the "have nots" of "gain of function" research). The “have nots” increasingly contribute to the notion that the natural origin story is only a theory that does not rest upon a hierarchy of genomic facts. It is heuristics until peer reviewed.
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David Rivard
9/23/2020 04:05:46 pm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405836/
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The Philosopher
9/23/2020 04:35:06 pm
Dear all:
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The Philosopher
9/23/2020 05:11:14 pm
https://www.bbc.com/news/world-us-canada-54244018
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Fuddman
9/23/2020 08:55:25 pm
“McConnell's wife, despite her family hailing from Taiwan, are actually pro CCP”
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The Philosopher
9/23/2020 10:40:49 pm
Wumao detected!
yano
9/24/2020 07:40:25 am
https://youtu.be/xJxlOgC9Yr0
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9/24/2020 11:31:25 am
What do you think of the finding that one of the primers used in WHO's covid-19 test kit is 18 bp that is identical to a part of human chromosome 8? Is that used as a positive control, or something else?
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The Philosopher
9/24/2020 12:58:48 pm
Source, Maggie?
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fuddman
9/24/2020 04:32:55 pm
https://healthfeedback.org/claimreview/human-dna-alone-does-not-produce-a-positive-result-on-the-rt-pcr-test-for-sars-cov-2/
fuddman
9/24/2020 04:49:46 pm
https://straight2point.info/one-of-covid-19-test-kits-rt-pcr-tests-for-humanc-hromosome-8/
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yano
9/25/2020 05:41:17 pm
Looks like a peer review is happening after all.
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Greg Felton
9/25/2020 06:17:25 pm
Yes, other coronaviruses have furin sites, but they are not linear b betacoronaviruses like SARS-CoV-2, which is unique in having them.
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The Philosopher
9/25/2020 09:42:41 pm
I can just read what they wrote, and compare it to what Yan wrote:
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The Philosopher
9/25/2020 09:51:29 pm
On second though, I retract that. How many poorly written emails will they receive? I regret that. My apologies. I do think that they should have read the Yan paper better and written a better rebuttal.
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yano
9/25/2020 10:09:48 pm
I'm happy they commented. It starts the dialog.
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The Philosopher
9/26/2020 01:00:17 am
Oh wow, that's a cute one.
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yano
9/26/2020 08:44:18 am
Those smart women. Maybe they do have husbands. Which one am I? :D
Babstar
9/26/2020 01:33:41 am
CDC Early release
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Xoco Latte
9/26/2020 10:23:28 am
Hmm, a bit of interesting: the U.S. CDC published a paper written by all authors from Hong Kong. WTF?
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yano
9/26/2020 10:45:36 am
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359528/
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The Philosopher
9/26/2020 12:44:07 pm
Wow, nice weird paper, yano. Definitely something I'll have to dig in to fully digest. However, at first glance, the abstract has some weird, quasi-nonsensical ideas.
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evidence
9/27/2020 08:58:47 am
Re: 'Questions to the WHO'
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yano
9/28/2020 05:24:58 am
https://twitter.com/JJ2000426/status/1264711207333720066
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Andrew M
9/30/2020 02:27:16 am
It's stretching a definition to call this "analysis". No mention of the possible effects of selection and recombination on the outcomes. It's more like whistling in the dark.
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yano
9/30/2020 08:12:08 am
I never said the analysis was correct. Obviously this is a difficult task and will require peer review and several iterations.
The Philosopher
9/30/2020 02:47:02 pm
@Yano:
The Philosopher
9/30/2020 02:49:37 pm
@Yano:
Greg Felton
9/30/2020 02:54:25 pm
Is there any consensus here on the validity of CD147 being a secondary receptor for SARS-CoV-2? I’ve come across a fair bit of discussion on it but also dismissive criticism.
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yano
9/30/2020 04:42:18 pm
@The Philosopher
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The Philosopher
10/1/2020 12:15:24 am
Thanks, Yano.
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Xoco Latte
10/1/2020 01:31:07 am
Not that I wouldn't agree with most of your points above, especially regarding the 20-yrs-old writer at Medium, but the RNA sequence coding for the furin cleavage site is, actually , part of the spike protein that is, again actually cleaved by furin and other specific protease enzymes. So, no, you are wrong, cleavage is not occuring between the two consequtive CGG codons but rather between the two Arg's.
The Philosopher
10/1/2020 06:09:29 pm
@Xoco Latte
Brian
10/1/2020 08:51:03 pm
Yan report:
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yano
10/1/2020 09:09:24 pm
We are waiting for Yan Report 2. It's going to be good.
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yano
10/1/2020 09:58:23 pm
From the Yan Report 1.
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yano
10/1/2020 11:36:54 pm
https://www.sciencedirect.com/science/article/pii/S1567134820303567
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Greg Felton
10/1/2020 11:53:03 pm
Since both Shi Zhengli and Peter Daszak have confirmed the fallacious origin of RaTG13, how is it possible for it to continue to be cited in scientific journals? Don't editors read? Also, about CD147 being an entry point for SARS-CoV-2: is this a sound theory?
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The Philosopher
10/2/2020 11:53:53 am
@greg felton
Lilian
10/4/2020 12:11:21 pm
How is it possible on the other hand, that RmYN02 is even closer than RaTG13 to SARS2 beside the exact complete ORF8 and the spike? Can they be exchanged like LEGO pieces?
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yano
10/4/2020 06:14:25 pm
Recombination is the nature argument. Yes, it's just magic from nature.
Greg Felton
10/2/2020 12:06:04 pm
Your point is well taken @ Philosopher. I perhaps should have said "have confirmed by their actions".
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The Philosopher
10/2/2020 12:37:00 pm
@greg felton
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10/2/2020 12:42:15 pm
Of course. On another topic, can you speak to CD147 as a receptor for COVID-19? This thread has a mention or two but not much. I have seen many journal articles on it but am not sure if the theory is valid.
The Philosopher
10/2/2020 03:17:50 pm
@greg felton
Craig Paardekooper
10/5/2020 06:55:29 am
When we hear that SARS_COV_2 mutates, does that mean it mutates naturally, or does it mean that bio-weapons scientists are still tweaking it to perfect its effects.
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CCP is NAZI
10/5/2020 10:34:40 am
I'm not surprised at all if bio-weapons scientists are still tweaking it to perfect its effects. Per https://www.abc10.com/article/news/crime/san-francisco-chinese-researcher-allegedly-harbored-at-consulate/103-296b2b54-a3bc-4893-a195-9f1ff52ba044, the Department of Justice said Tang Juan applied for a non-immigrant J1 visa around Oct. 28, 2019 and alleged Tang of making fraudulent statements on her visa application. Note that the first case of CCP virus in Wuhan started on Sep 18th,2019, https://twitter.com/jenniferatntd/status/1229921498464505856. She
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The Philosopher
10/5/2020 11:35:30 am
It mutates naturally by replicating in the host cells.RNA dependent RNA polymerase (RDRP) can "slip up" or make mistakes and insert the wrong nucleotide bases during replication, which is one of the ways mutations can occur. I've posted sources earlier which can explain, I think, that this process happens a lot for viruses (the mistakes), hence the high mutation rate, typically.
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Xoco Latte
10/7/2020 03:59:07 am
CoV RdRp has a built-in autocorrection capability that could significantly lower the mutation rate compared to other type of viruses, hence, reduce the number of erroneous transcripts.
CCP is NAZI
10/8/2020 08:11:57 am
Dr. Yan's second scientific report is published in zenodo today. Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route:
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yano
10/8/2020 01:44:24 pm
Yan Report 2 "1.4 The receptor-binding domain (RBD) of RaTG13 does not bind ACE2 of horseshoe bats Consistent with the above conclusion that RaTG13 does not exist in nature and its sequence was fabricated, a recent study showed that the RBD of RaTG13 could not bind the ACE2 receptors of two different kinds of horseshoe bats, Rhinolophus macrotis and Rhinolophus pusillus 45 . Although the ACE2 receptor of Rhinolophus affinis (the alleged host of RaTG13) was not tested, it is unlikely that ACE2 of R. affinis would differ significantly from those of its close relatives and be able to bind the RaTG13 RBD."
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The Philosopher
10/8/2020 03:52:30 pm
This is getting weird.
Xoco Latte
10/9/2020 07:00:09 am
Dr. Yan says two things.
Xoco Latte
10/9/2020 08:09:35 am
I seriously think these papers are the Khalezov-reports of the SARS-CoV-2 pandemic...
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The Philosopher
10/8/2020 12:49:15 pm
Dr. Yan's mother was recently arrested in China.
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yano
10/8/2020 02:17:02 pm
"Dr. Yan's mother was recently arrested in China."
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The Philosopher
10/8/2020 03:57:19 pm
This is the CCP, look up their common scare/intimidation tactics. They do this all the time to silence dissidents. they have much to hide!
yano
10/10/2020 06:33:57 pm
Some peer reviews of Yan's Report 1
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Xoco Latte
10/11/2020 12:39:20 am
IF Yan's first report is anything but a scientific proof of RatG13's being a fraud, these 4 "reviewers" did not care too much to overdo her in terms of scientific evidence gathering.
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Xoco Latte
10/11/2020 12:52:47 am
In other words, these are just the usual, low-quality nit-picking smear campaign elements.
yano
10/11/2020 08:57:10 am
Agreed, the "peer" reviews seem to be lacking in science.
yano
10/11/2020 08:37:08 am
Can R affinis be infected with Ratg13?
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yano
10/11/2020 09:13:55 am
2014 paper Ref 15 cited paper from above. Maybe LYRa11 is of some help.
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Nerd has power
10/11/2020 07:57:39 pm
Sorry for the radio silence for the past few weeks. But the discussions here have been great (and long)! I think much of the scientific points raised have been answered in the exchanged comments and some by the 2nd Yan report. I will be around more often from now on (at least for a while) and contribute intellectually as much as I can!
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Interested One
10/12/2020 04:55:36 am
I really want to stay publicly away from this debate, but after reading the "peer reviews" of the Yan paper I'm going to make a brief comment.
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alex
10/12/2020 07:46:00 am
Again I ask Interested One. About the almost zero incidence the virus in China.
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Xoco Latte
10/12/2020 08:03:28 am
Well, I do not know about Thailand, Taiwan or South Korea, but I LOL abot the naivity of your question with regards to the RPC. I suggest more than usual reservation to be applied to REPORTED incidence figures on Worldmeter and tried to make a clever estimation of TRUE incidence rates. Not only because incidence figures of new infectious cases clearly depend on the frequency of PCR testing, the strictness in methodology of lab sampling, the false negative results rate of the PCR tests, but also due to the politically biased adjustment of test results.
alex
10/12/2020 09:45:33 am
Xoco, I am not referring to the PCR results, nor do I look at them, I am referring to the mortality data, excess mortality, a "covid peack" is not detected in any of these countries. As for example in Italia, Spain, Belgium. Assuming the data is correct.
yano
10/12/2020 11:54:49 am
You can say the same for Uganda, New Zealand, Cad, Cuba and Fiji. I think some countries are just much better at controlling the virus spread.
The Philosopher
10/14/2020 06:33:53 am
@alex
Xoco Latte
10/14/2020 08:25:59 am
@alex: I am sorry but you asked about incidence - the definition for incidence is the number of new diagnosed cases in a given time period. Mortality is what means the frequency of deaths that are attributed to a disease.
yano
10/12/2020 01:30:02 pm
"Additionally, no one person to date has discussed the rare stable appearance of CGGCGG in this site, and its apparent lack in any coronavirus evaluated to date."
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Nerd has power
10/12/2020 07:48:46 am
So far, none of the volunteered peer reviews are really judging the science. As stated in the 2nd Yan report, point-to-point responses will be published in responding to these “peer reviews”. I don’t believe truth will be distorted or hidden forever. Discussion helps in clarifying things, just like what’s going on here on this forum.
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yano
10/12/2020 08:42:28 am
"As of the affiliation with the Rule of Law Foundation, it is sad to see how people think negatively about it."
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Neutural Observer
10/12/2020 09:16:29 am
I haven't liked or disliked the Rule of Law Foundation until some REAL anti ccp folks have been attacked at their homes which makes me wonder if the Rule of Law Foundation is really anti CCP like what they claimed. Initially, I held a neutral view about the Rule of Law Foundation. I don't jump into a conclusion to a point to quickly like or dislike something until I can fully observe what it is there for. I tend to think more before next action. But when you play a video like https://www.youtube.com/watch?v=k4Qywy9B5G8(especially starting at 4:22), things start to get nasty. I am a fan of Wu Juan Ming who is a June 4th activist and went so far to give up his first love by not signing what CCP forced him to sign. I could feel his broken heart and teared for what he has sacrificed for the democracy and freedom of China. If I have to pick one between Guo Wengui and Wu Jianming as a pro anti CCP, I would definitely pick the latter. We are in the United States and should enjoy the freedom of speech. Why would Guo Wengui send people to harass Wu Jianming everyday until Wu quits his YouTube channel?
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chime
10/12/2020 05:03:48 pm
There is no right for this speech starting at 4:22. The video is fighting words and is not covered under the US free speech laws. I'm sure if you point this out to youtube, it will be removed. Calling for someone's death is the definition of fighting words. It also could be viewed as inciting violence which is also not allowed under US free speech laws. As far as someone being intimidated, sounds like gang activity. There are also laws against that. Sounds like the "Rule of Law" needs to be applied equally for everyone. I love the science here. Thank you for that.
Nerd has power
10/14/2020 10:27:02 am
The definition of “REAL anti CCP” could differ between you and me. A lot of people in this world still see Zhengli Shi as a reputable, innocent, and REAL scientist. I’m certainly NOT in that camp.
Neutral Observer
10/14/2020 01:01:53 pm
I didn't intend to bring up anything irrelevant to the topic here to
Nerd has power
10/14/2020 08:54:41 pm
Thank you very much for sharing your views and being open-minded. I think I should refrain from giving anyone much of my political views. This forum is not for that, and also I cannot guarantee that I'm not biased. But I think it's safe to say that keeping an eye on both sides helps. Let their actions help us decide.
Interested One
10/13/2020 05:00:05 am
While we all debate the viral origin and we await a vaccine or better therapeutics, here are a few thing healthy things we can do that quite possibly reduce our ability to get the virus, and if we do get it, perhaps reduce our chances of dying. This does not replace any advice that you would get from your doctors, since nobody is allowed to practice medicine over the internet.
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yano
10/13/2020 09:15:07 am
I went back to look at the timeline.
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Traveler
10/13/2020 02:33:06 pm
https://www.minervanett.no/alina-chan-coronavirus-covid19/contradicting-statements-cast-doubts-on-chinese-raw-data/364540
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Nerd has power
10/14/2020 10:45:18 am
Okay, I will try to explain it here. These raw sequencing reads/data were uploaded in 2020. However, they were uploaded as individual files and the original filenames remain visible after the upload. When people checked these freshly uploaded raw sequencing reads, they noticed that these files are named in a way that the date of sequencing was incorporated.
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yano
10/14/2020 09:36:28 pm
Nerd said
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Jenny
10/14/2020 11:55:19 pm
A curious case of the missing ACE2 1-131 in every single known dataset of R.affinis
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yano
10/15/2020 08:23:27 am
Data availability. The complete ACE2 sequences of R. sinicus and R. affinis ACE2 obtained in this study have been deposited in the GenBank database under accession numbers MT394181 to MT394201 and MT394203 to MT394225, respectively.
The Philosopher
10/15/2020 07:22:29 am
Who said what now? Can you at least re-write your comment so we can see who's saying what claims and where?
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yano
10/15/2020 08:25:52 am
The quotes are from this paper. Please read and comment.
The Philosopher
10/16/2020 10:29:31 am
@yano
yano
10/15/2020 05:12:42 pm
Do you think these people
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Nerd has power
10/17/2020 08:35:38 am
Yes, Mou and co-authors had the obligation to test it. Their work has been cited in the Yan reports. The world knows that they could do this test and bring an answer to this question.
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yano
10/17/2020 04:34:32 pm
"The potential benefit of the recent Shi paper is obvious. Even if Mou or someone else would prove that RaTG13's Spike binds human ACE2 better than R. affinis' ACE2, Dr. Shi could point you to this JVI paper of hers and remind you that it is normal because we have seen it in R. sinicus."
fuddman
10/18/2020 01:52:24 pm
" Isn't there a chance that Dr. Shi has been encouraged by her previous success(es) of similar kinds to courageously publish another fabricated virus this Jan?"
Percy Dovetonsils
10/18/2020 03:09:45 am
RaTG13
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Greg Felton
10/18/2020 03:41:55 am
How is this possible since both Shi Zhengli and Peter Daszak have admitted that RaTG13 is BtCov/4991?
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Nerd has power
10/18/2020 05:02:13 am
Thanks for the info!
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The Philosopher / alabasterCrown
10/21/2020 01:15:58 am
OK all, we're done. I'm done. This should be it! This should be enough proof!
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yano
10/21/2020 03:34:13 pm
I like this part,
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Nerd has power
10/24/2020 04:56:38 am
Thanks for sharing these two articles. Excellent work done by both groups of scientists. I'm not an huge expert in bioinformatics, so I can't vouch for the veracity of the bioRxiv preprint. But I like their conclusion a lot though:
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yano
10/25/2020 10:58:54 am
"I wonder what they would see when another coronavirus is put up for the same test (molecular mimicry on the peptide level)"
fuddman
10/25/2020 02:50:16 pm
".....there is a chance that this vaccine is going to be more harmful to you than to the virus...."
Nerd has power
10/29/2020 02:57:14 pm
Yano:
David Rivard
10/21/2020 08:16:18 am
(So what animal species has such peptide sharing between SARS-CoV-2 spike glycoprotein and mammalian and coronavirus proteomes…the common laboratory mouse species. Not the bat that certain GOF scientists cite?)
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yano
10/21/2020 04:07:39 pm
@The Philosopher. Yes, this really sucks. Seems this virus is a human virus trained in human mice. It would have been better if it was from nature, it would be less perfect. A depressing read.
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Nerd has power
10/21/2020 09:25:53 pm
Here is an entertaining piece from the CNN:
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Nerd has power
10/21/2020 10:01:47 pm
I also updated my "ABOUT" tab just so that no other reporters would be "confused" again!
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yano
10/21/2020 11:13:11 pm
This is hilarious! OMG the charts are the same. AND even Facebook says its false. :) Thanks for the good laugh.
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Nerd has power
10/24/2020 05:12:56 am
I don't know whether you can call the Johns Hopkins review "the best". I don't really see any quality in any of their arguments. I'm amazed how Connell and Gronvall dare to speak on CNN and describe the Yan reports as garbage. If I were them and had produced this self-destroying, pretentious "peer-review", I would hide away from the public as much as possible. But that's just me. People care about different things. I think they are anxious to see the responses too, just a different kind of "anxious".
yano
10/24/2020 08:34:47 am
@Nerd "I don't know whether you can call the Johns Hopkins review "the best"."
alex
10/22/2020 07:15:42 am
Tonigh at 22:00 hour in Spain, interview with Dr. Yan in telecinco.
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David Rivard
10/22/2020 02:52:10 pm
mmm, Mighty Mouse once said; "Are we mice or are we men?"
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alex
10/22/2020 11:55:03 pm
Here the interview with Dr Yan.
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Xoco Latte
10/27/2020 07:11:37 am
An interesting and perhaps important new paper at bioRxiv today:
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John Doe
10/31/2020 09:34:01 pm
"There is a lot we do not know about what coronaviruses China has collected, how accurate the sequences are and how they might have been manipulated.
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Nerd has power
11/1/2020 08:55:10 am
Thank you for sharing this info. Yes, during the fabrication process, they must have made more mistakes than what has been pointed out in the 2nd Yan report. This is another excellent example. RmYN02, pangolin coronaviruses (including MP789), RaTG13 are all fraudulent --- It cannot be more obvious. If we look harder, we will certainly find even more proofs.
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Mister1k
11/1/2020 03:12:43 am
Are you all still chasing your tails?? Your being played..explain this article.
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Mister1k
11/1/2020 03:16:58 am
I can't begin to understand it.But SarsCov,SarsCov2,SarsCov3 and PCR. They built it.
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Nerd has power
11/1/2020 09:07:19 am
Thank you for the article. I think the paper is about devising a system for convenient packaging of long RNAs. They chose to name their tested SARS variant genomes: SARS-CoV1, SARS-CoV2, SARS-CoV3. However, their SARS-CoV2 is not a virus and is different from our famous COVID-19 pathogen, SARS-CoV-2. It's just the namesake of it.
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yano
11/1/2020 05:37:48 pm
I like these Norwegians
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Annette
11/16/2020 06:29:35 am
I am following this discussion but am not literate in the finer details of gene exploration. I still believe that we must look now to what is perpetuating it. SARS Covered -2 has taken hold and does seem to be resistant to long term immunity. What is stopping it. Will the CaMV cassette in plants mediate infection.
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yano
11/1/2020 05:45:55 pm
Birger Sørensen said,
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yano
11/1/2020 05:48:12 pm
"Furthermore and significantly, Zhan et al also note that, surprisingly, this characteristic is present from the very first isolate (Zhan et al, 2020). This is something that does not sit well with an hypothesis of natural evolution."
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Nerd has power
11/1/2020 07:41:12 pm
I read their paper sometime ago and forgot some details. It's interesting that you brought up the "rolling window of 6 amino acids" thing. It basically echos with the molecular mimicry finding that we have just discussed:
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Nerd has power
11/1/2020 09:26:07 pm
Adding to it is this new Science paper:
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yano
11/2/2020 12:53:51 pm
Nerd,
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Nerd has power
11/2/2020 08:57:31 pm
I don't know. I have been skeptical about all the good news of certain vaccine trials being promising at early stages. I will take one if it has gone through all the tests and show convincing results in terms of both safety and effectiveness. I think this is everyone's preference. It may be hard to achieve though given what we have learned recently.
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The Philosopher / alabasterCrown
11/3/2020 11:29:08 am
vaccines will not be efficacious and have too many side effects (J&J getting halted, for example)
yano
11/3/2020 02:38:22 pm
Please ask her about the Biovacc-19. This theory about targeting the 20% part of the spike NOT in the human domain seems critical.
Nerd has power
11/4/2020 08:28:45 pm
Sadly, Dr. Yan does not have a lab to work in anymore. Plus, it takes a village to do the vaccine work. And even if Dr. Yan has a team and a lab, only one or two ideas could be tested by her with no guarantee that something will definitely work out.
Nerd has power
11/5/2020 09:33:33 pm
I have to add one thing. Vaccines are developed against existing viral strains. When the virus mutates, there is a chance that vaccines may become less effective or completely useless. That's why flu vaccines fail all the time.
yano
11/4/2020 02:30:12 pm
More bad news
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Xoco Latte
11/9/2020 01:30:56 am
More than disturbing news... Especially from the viewpoint of a restarting epidemics with a mutated clad that becomes more and more adapted to an intermediate host as well as to humans.
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keith
11/4/2020 02:48:52 pm
This vaccine candidate could address mutation issues raised:
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Nerd has power
11/4/2020 08:31:19 pm
Thank you for sharing the news. It's a novel approach and is definitely promising. However, it's too early to judge it though. The real challenge/test is still ahead.
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Jst
11/9/2020 08:57:20 am
Pfizer BNT162 vaccine
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Jst
11/9/2020 08:58:06 am
is here
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Nerd has power
11/15/2020 05:26:02 am
It's been quiet here for a few days. In case anyone is paying a visit and looking for news on the topic, here is an entertaining piece from the WashingtonPost:
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alex
11/15/2020 08:10:11 am
And What do you think about this iniciative?
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Nerd has power
11/18/2020 04:59:35 am
WHO would not be the one to bring a true answer to the origin problem. That is my opinion.
alex
11/18/2020 08:31:59 am
Thanks for answering,
Nerd has power
11/18/2020 09:17:13 pm
I read this paper and have commented on it on twitter:
alex
11/23/2020 10:27:23 am
Nerd thanks again for answering. I try to answer.
Nerd has power
11/25/2020 05:29:13 am
Thanks for the analysis, Alex. Yes, I agree that we have to be open-minded. But we also have to be alert because, while the main narratives are apparently being controlled by a certain force, it is not the only strategy that this force uses. They also try to mislead you in subtler ways.
Gerhard
11/16/2020 10:40:49 am
On Sept 14 2020, Italian TV (RAI 3) had an interesting documentary with many interviews about the origins of SARS-CoV-2
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11/16/2020 11:03:58 am
Great comments by Nerd on 11/5/2020 and with the later WHO articles in mind, it is becoming a year and the virologic community cannot arrive at a consensus about the origin of C-19. It seems that even a general assessment of its origin, natural or artificial, has been heartedly discouraged. It is logical that so much of therapy and vaccine development depends upon understanding the origin of C-19 with certainty.
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11/16/2020 12:25:13 pm
Here is the logical starting point for congressional information:
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Nerd has power
11/18/2020 05:08:59 am
Thank you for sharing your thoughts. There are many things that are out of our control, but we can at least help spread the truth. Every little bit helps. Maybe things will take a turn before we know it.
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Xoco Latte
11/17/2020 02:49:54 am
Another new preprint on molecular mimicry of the SARS-CoV-2:
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Nerd has power
11/18/2020 05:17:57 am
Took a quick glance. They seemed to have looked more than just the Spike. Interesting. I don't know whether host adaptation would be the reason. I'm doubtful myself. And yes, they should look at true naturally-occurring coronaviruses and see how the molecular mimicry thing may look over there.
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David Rivard
11/18/2020 09:12:49 am
As this site has become my 1st. go to for this information, I became truly alarmed this morning when your email notification link produced a non-existent page. I thought, "I hope all of this work hasn't been lost", and "they got him too". I keep wondering how we can expand this forum.
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Nerd has power
11/19/2020 04:46:35 am
Thanks, David. Let us know your ideas. I'm sure many here want to learn how to better spread the truth.
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Curious George
11/18/2020 11:24:31 am
https://www.nature.com/articles/s41586-020-2951-z
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11/18/2020 05:35:54 pm
I came across the above news article from Aug 2018, that ridiculed China for refusing to share samples of an emerging strain of H7N9. I’m of the assumption that the samples in question were from a 2017 outbreak in the Hubei province.
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Aquapontanus
11/18/2020 05:40:05 pm
https://www.livescience.com/63448-china-h7n9-flu-samples-pandemic-prevention.html
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Babstar
11/18/2020 10:32:29 pm
EcoHealth Alliance orchestrated key scientists’ statement on “natural origin” of SARS-CoV-2
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Xoco Latte
11/19/2020 01:35:20 am
This is exactly the reason that I feel CCP and WIV are not the only stakeholders in this effing story.
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Nerd has power
11/19/2020 05:44:55 am
Thanks! Great, great info. I encourage everyone to not only read the article but also dig into the 466-page email records. There seems to be much interesting info in there. At the very least, you will be more amused next time you see these people (Peter Daszak, Linda Wang, etc.) acting in interviews.
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Brian
11/21/2020 09:25:18 am
So a meteorite bring this virus on October 11 2029?? WTF!
Nerd has power
11/22/2020 05:51:37 am
Linfa Wang, not Linda Wang :D
Nerd has power
11/23/2020 07:23:57 pm
Brian, I think the meteorite theory was proposed by someone outside of the EcoHealth Alliance circle. That person sent his meteorite hypothesis over to EcoHealth Alliance, trying to get their support. I think the EcoHealth Alliance people were making fun of this person and the meteorite theory as well.
manhp
11/18/2020 10:32:41 pm
With regard to February 2020 Lancet statement:
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11/21/2020 10:21:54 am
Yes, I think, like it or not, it is about time to take this forum to the next level. Ideas I have:
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Nerd has power
11/22/2020 06:05:17 am
Thank you for the ideas. Cataloguing the useful links is something I can do. But I can only pool the links that I can vouch for. There are other theories out there, which, although pointing to a lab origin, deviate from what I believe is the truth.
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Nerd has power
11/22/2020 06:37:32 am
I added a "LINKS" page, where all the Yan official reports and responses are listed.
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11/22/2020 06:57:41 am
https://www.healthline.com/health-news/leaky-vaccines-can-produce-stronger-versions-of-viruses-072715
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Nerd has power
11/24/2020 04:06:33 am
Thanks for sharing. Yes, I agree that leaky vaccine could potentially lead to the spread of more virulent strains. However, this seems to depend on what exactly is defined as "leaky". In the original paper, it seems to talking about a vaccine that does not block viral transmission but reduces symptoms. This type of "leaky" is the perfect for the creation of more virulent strains.
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Peter Ross, PhD, MD
11/23/2020 04:58:16 pm
In studying the origins shall we acknowledge the lockdownistas - who clearly schemed-out long ago this medical martial law / globalized slavery trick?
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Nerd has power
11/24/2020 04:35:28 am
Yes, lockdown or no lockdown, that is the question. Everyone has his or her own opinion on this question. With the virus still being around, this debate can last for a long time.
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David Rivard
11/24/2020 01:43:08 pm
Interesting viewpoint.
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Guy Fawkes
11/26/2020 06:13:38 am
I did not find Apolone et al. (2020) "Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy" @ https://doi.org/10.1177/0300891620974755 mentioned for now on this site. Quote:
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alex
11/26/2020 07:37:35 am
I recommend you read the article, you can find it here:
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Guy Fawkes
11/26/2020 06:19:30 pm
Thanks Alex, my DOI-link redirects towards the same page. Indeed, it goes without saying that I also recommend reading the paper in full, it was published October 29, 2020. There are some nice jewels in it, here some excerpts:
Guy Fawkes
11/26/2020 06:24:43 pm
- PART II OF THE MESSAGE ABOVE WITH A LITTLE OVERLAP -
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Nerd has power
11/26/2020 08:56:52 pm
Thank you for the analysis. First, let me comment a bit more on this Italian paper. Antibody tests can be complicated. There has been observations that anti-SARS-CoV-2 antibodies could cross-react with other viruses (I will try to dig out that paper). Therefore, even if the experiment was done perfectly, there is still a chance that those 2019 blood samples in Italy had other viral infections.
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Guy Fawkes
11/27/2020 12:51:17 pm
Thank you NERD for your kind reply. Please don't get me wrong, of course I read your 2nd Yan-report in full as well and found it outstanding and outspoken, yet the 1st was an awesome concentrate on all the comments & 3rd party links over here from the past 6 month into one pub, thus priceless in making a long story short.
Nerd has power
11/29/2020 06:01:05 am
Thanks for sharing your thoughts. I will respond to a few points you touched.
Nerd has power
11/27/2020 10:05:46 am
Here is an article written by a fellow blogger, humblescientist. A very good piece in my opinion:
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Guy Fawkes
11/28/2020 04:23:15 am
Thank you for the link to "The coronavirus research that may have led to COVID-19", there is also a PDF-version of it for offline reading:
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Nerd has power
11/29/2020 06:10:04 am
Thank you for the suggestions. I can try to explore a bit. Please don't put too much hope though because I'm embarrassingly incapable of managing webpages :)
alex
11/28/2020 08:26:23 am
new attempt to throw balls out
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David Rivard
11/28/2020 09:04:44 am
The fact that Lancet, without evidence, continues to publish variations of the CCP's natural origin story, while not accepting lab origin papers with many more credible citations not only undermines their credibility, but makes them complicit in this global tragedy. Rather than giving equal exposure to both natural or lab origins, the editors have chosen to give the CCP a veneer of science as they continue force others to waste resources in either defending or dis-crediting their new inventions. Also, as a part of the disclosures, every article from Chinese academia should disavow any interests by the CCP. Academia (Lancet, et al) must warrant this new standard as another layer of truth for the sake of more efficient prevention, vaccine and therapeutic development. Is Lancet identifying as part of the CCP apparatus?
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Guy Fawkes
11/29/2020 02:23:35 pm
So Italy is off the table, as stated in the Guardian article NERD pointed to:
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Nerd has power
11/29/2020 05:51:42 pm
Ok, Guy, take a look at these records:
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babstar
11/29/2020 11:29:57 pm
Interesting choice of MERS as a pandemic model. The one big difference is the low R0 (estimate 0.50 ~ 0.69) and the lack of self sustaining chains of transmission outside health care settings. It has a relatively low prevalence in Saudi Arabia, predominately among Camel herders. Not the virus you would expect from Military age males from the Middle East.
Guy Fawkes
11/30/2020 01:20:02 pm
Ok NERD, first, let me thank you for this awesome exchange!
Fuddman
2/24/2021 02:40:59 pm
"....dictators do not care about the lives of people. "
Annette
11/29/2020 08:58:25 pm
"This, coupled with "T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted " in Diao et al. (2020) "Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)", it's not a nice outlook at all. Hence, bioweapon it is, especially in the long run, with reactivations at lower levels of lymphocytes." This virus is acting like a retro virus has anyone done any study to see if a retro viral base pair code has been inserted.
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Nerd has power
12/1/2020 06:02:13 am
I think SARS-CoV-2 does not infect T cells or immune cells in general. Please correct me if I'm wrong. So, not exactly like retroviruses. Some also have suggested that SARS-CoV-2 genome has insertions of HIV sequences. However, I am not convinced about such insertions. I commented about this a few times already, but I'm sure nobody could find them now with over 1200 comments here.
Guy Fawkes
11/30/2020 01:25:17 pm
@ANNETTE: It would be very interesting to know if a retro viral base pair code has been inserted.
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Nerd has power
12/1/2020 05:52:19 am
Thank you for the info and discussion. Yes, as individuals, we all need to do the best we can to avoid it. That helps with minimizing the overall spread as well. Personally, I will continue to stay cautious about the vaccines. Like everybody else, I really hope they work. But there are significant unknowns and the recent news from Pfizer and Moderna are a bit suspicious IMO.
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Guy Fawkes
12/2/2020 12:44:27 am
@"I think SARS-CoV-2 does not infect T cells or immune cells in general. Please correct me if I'm wrong."
Nerd has power
12/3/2020 05:21:58 am
Thank you! So I was wrong. T cells can indeed be infected by SARS-CoV-2.
David Rivard
12/1/2020 10:25:22 am
@Nerd, I concur. You must have inherited some historian gene along with your scientist gene. Only those fully immersed in our current comfortable society with our values of a concurrence of goodwill will not see that when wars were initiated in the past, perpetrators do not see collateral damage as an issue. They will only start war if they perceive many tactical and strategic advantages, along with the element of surprise. They have been given a lot of time to keep this element through our scientific publishers and have the critical maintenance through several UN agencies. Their first vanguard is of course the critical question you address; natural or artificial. The second will be; intentional or not...and, they go to war to absolutely vanquish their enemies.
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Nerd has power
12/1/2020 08:16:23 pm
Thank you, David. Very well said.
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Guy Fawkes
12/2/2020 02:27:01 am
@David Rivard: I fully agree. Yet your first point "natural or artificial" has been answered in all the pubs above beyond a reasonable doubt - aka it's artificial. Now about the "intentional or not", if it came from the WIV, and was the result of GOF, they made all those drills, then turned one live [remember Operation SOUTHERN MISTRAL just before the Libyan war, or those countless (up to 46 !) drills on 9/11], perhaps it went out of control Chernobyl-style and - as NERD suggested - perhaps they even helped spreading it worldwide to cover up their hotspot and fuel the mess [would also explain all those ex post facto pathetic intermediate host-fabrications], then your second question about intentional or not is also answered - aka intentional. How nice.
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Nerd has power
12/2/2020 10:18:20 pm
Guy, thank you for the comments and perspectives. I fully respect your views, although I do not agree with them in full. Let me share a bit more about what I consider as "the world" and who could save the questionable thing I referred to as humanity.
Nerd has power
12/3/2020 05:10:20 am
I would like to add two more points (I was half asleep typing the above last night and failed to express myself in full).
David Rivard
12/2/2020 10:30:29 am
@Nerd, thanks for allowing us to come up for air in our departure from pure virology now and then. It's the reminder we all need of why we must plunge into the depths again until we retrieve enough of the truths that are rapidly accumulating in the net awaiting us above. I mentioned Voltaire as my previous apology for not being in the virology field (all fields of inquiry being only artificially separated), so thanks again.
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David Rivard
12/2/2020 10:53:34 am
In addition, this site probably has the largest readership, no?"
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Guy Fawkes
12/2/2020 02:47:16 pm
Thank you for your kind remarks, David! I'm delighted if I could leave a positive fingerprint behind here and there.
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Peter Ross
12/3/2020 09:31:01 pm
If there's no traces of virus on the mask it's not doing such a great filter job! Anybody testing that?
Peter Ross
12/2/2020 12:39:05 pm
There is no pandemic, only fear of a pandemic from a self-disseminating vaccine called SARS-CoV-2 .
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alex
12/3/2020 08:33:49 am
Can you expand this comment?, please, I do not understand well what you say
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Peter Ross
12/3/2020 09:18:35 pm
Scientists are working on vaccines that spread like a disease ...thebulletin.org › Disruptive Technologies › Biosecurity
Greg Felton
12/2/2020 01:12:55 pm
Greetings Nerd and others:
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David Rivard
12/2/2020 07:45:33 pm
Thanks Greg, I'll both read it and shop it around for you. Another great outcome for this site.
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Greg Felton
12/2/2020 07:53:07 pm
Much obliged, David: I just did an interview out of England and my publisher is lining up others. I give a plug to Nerd has Power whenever I can.
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Nerd has power
12/2/2020 09:25:21 pm
Greg, glad to learn that your work has already come to fruition. I'm sure it will bring more people closer to the truth. Big congratulations!
Peter Ross
12/4/2020 07:48:33 am
https://www.wionews.com/opinions-blogs/are-the-global-scientific-elite-trying-to-bury-the-truth-about-the-origin-of-covid-19-332583
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Guy Fawkes
12/4/2020 01:20:18 pm
@Peter Ross: Wow Peter, so much to muse about in this wionnews-article, pure awesomeness:
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Guy Fawkes
12/4/2020 01:24:24 pm
...
David Rivard
12/4/2020 08:03:54 pm
But I think it is a brilliant bioweapon because it does not kill right away. It is sufficiently dangerous as it devitalizes individuals, economies and political systems. The long haulers are still long haulers after 10 months. There are millions of them. In all countries it seems that roughly half of those that test positive are in some way symptomatic... devitalized. It seems to be the perfect remedy for both capitalism and personal freedom. I am waiting for a more robust China to start replacing more 3rd world institutions that have been supported and dominated so long by the United States. The US still has a corner on the market with security operations in most of these countries. You will see their replacement very soon. Our politicians seem to be primarily focused on the silver bullet of a vaccine. I think we all have a lot of questions about how that is going to be actually limiting the infection rate, never addressed. So far their tactics have been brilliant.
Greg Felton
12/4/2020 04:33:00 pm
Inasmuch as I agree with you and Lawrence Sellin, it is not advisable to use generic epithets like “global scientific élite” or “psy-op”. This is empty rhetoric, which those who are inclined to disagree with us can claim are merely conspiratorial clichés, however accurate they may be.
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Peter Ross
12/4/2020 04:55:55 pm
Guy Fawkes
12/5/2020 12:03:02 pm
@Greg Felton: Thx, but it was Colonel Lawrence Sellin himself who used "global scientific elite" in his title. I think any public statement on the internet should be taken with a grain of salt, especially when coming from somebody directly connected to the military. I guess he is right on target, but never underestimate the spectacular achievements of propaganda [to paraphrase Chomsky], ergo, IMHO, having "psy-op" projected at the back of one's mind is certainly a good idea when reading such articles. But let's agree to disagree, I'm perfectly fine with that.
Peter Ross
12/5/2020 07:32:52 am
Psychological warfare campaigning?
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David Rivard
12/5/2020 09:25:21 am
Sun Tzu: "The supreme art of war is to subdue the enemy without fighting", "Be extremely subtle, even to the point of formless".
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alex
12/5/2020 09:30:42 am
@Ross
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Peter Ross
12/5/2020 12:07:27 pm
@Alex
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12/5/2020 12:39:14 pm
@GuyFawkes: Thank you Guy. I am certain you;'d like it. I take your point that Sellin was the source of the terms I criticized, but I think you may have misconstrued my point. Whether or not boilerplate rhetoric like "psy-op" or "global scientific elite" is accurate is not the point. These are generic, hackneyed buzzwords that say nothing in particular. Anyone, no matter how informed or ignorant, can hurl them with equal force, so it is not possible for these terms to be taken seriously or carry any "useful info." By sheer repetition, they become less and less useful.
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Guy Fawkes
12/5/2020 03:12:22 pm
Thank you for your kind reply, Greg. I tried to put those said terms into context, by explaining my vantage point on a) research groups which are international, and thus compartimentalized 20th century nation-think is oldschool & b) that it's always helpful to first understand who is saying something, and as soon as the cavalry is involved, one should always think twice.
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Greg Felton
12/5/2020 04:06:05 pm
Thanks, Guy:
Guy Fawkes
12/5/2020 05:26:15 pm
You are more than welcome, Greg. And you really don't have to apologize, it's ok you need a little more proof in your tasty psy-op-pudding. Why don't you get a taste of the delicious U.S. Air Force Project by Hungerford (1950) "The Exploitation of Superstitions for Purposes of Psychological Warfare", I'm sure you will like it:
Guy Fawkes
12/5/2020 04:55:12 pm
@NERD: A week ago, you wrote "I reiterate: it was always for MERS, not HIV, not Ebola, not Dengue, not ZIKA ... Yet, since 2018 and more frequently in 2019, they REALLY practiced how to face a MERS emergency."
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Peter Ross
12/6/2020 07:54:59 am
Coronavirus may cause long-term erectile dysfunction in men, warns expert
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Nerd has power
12/6/2020 08:52:41 am
Could it be a vaccine development gone awry? I do not believe so.
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Peter Ross
12/6/2020 10:35:44 am
Just because SARS-CoV-2 looks like a vaccine-virus doesn't mean it's not a deliberate release - because "Wuhan" would never use a vaccine-virus as a weapon?
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Peter Ross
12/6/2020 11:50:53 am
If SARS-CoV-2 is an escaped vaccine-virus delivered by respiratory route that occasionally causes severe-but-treatable-illness in an identifiable cohort, then why is BigPharma making weird vaccines that are bound to be ineffective and of unknowable safety?
Guy Fawkes
12/6/2020 03:31:27 pm
NERD is of course right, chronologically, if they played around with an on purpose fabricated RaTG13 back in 2018, an accidental leak in 2019 does not explain the need for an earlier fabrication of a natural origin dummy beforehand. Only if they feared industrial espionage a lot, I mean a lot lot.
Nerd has power
12/6/2020 09:07:15 am
Dr. Jonathan Couey and Dr. Li-Meng Yan had a live discussion of the Yan reports yesterday:
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alex
12/28/2020 07:47:29 am
Nerd, Do you know if there is a transcript of this convesation?
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Guy Fawkes
12/6/2020 11:52:47 am
There were some postings back in June 2020 about CoV-2 and interferon. Here a paper from August 11 by Shi et al. (2020) "Opposing activities of IFITM proteins in SARS-CoV-2 infection", notably "using both gain- and loss-of-function approaches", quote:
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Peter Ross
12/6/2020 05:49:29 pm
Yeah, here is this theoretical issue of a latent disposition for any infection, and in particular for retroviruses, but why consider it for any human coronavirus infection?
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Guy Fawkes
12/7/2020 03:13:39 am
Sorry nerds, my 'autistic wall of words' was again too long and ate the link, here the full DOI to Gaebler et al. (2020) "Evolution of Antibody Immunity to SARS-CoV-2":
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David Rivard
12/7/2020 10:18:17 am
Guy, great comments as usual. Since Feb. I have been posting that the only effective science for combating the virus is the science of avoidance. It is amazing to me that almost 1 year later it is still the case. The CCP, in fact' seems so confident in its control of C-19 epistemology that it is expanding land claims in all countries around its borders, including Tibet, Bhutan, Tajikistan, India, Nepal and even my old military Alma mater Vietnam. WION and many other news services in Malaysia, India, Philippines, Japan et al are increasingly hosting stories about the CCP's intentional release. It is encouraging that they are also lumping WHO and several other UN agencies and even includ money laundering operations of several large ECOSOC accredited NGO's like Amnesty International. Pompeo initiated a version of the ASEAN NATO about a month ago after preparing it for over a year. Popular constituencies in these countries are increasingly demanding at least commerce and banking related retribution. My hope is that the incoming U.S. State Department can keep pace with what amounts to a regional uproar over the virus and a current CCP land grab. What worries me more in terms of the virus is the certainty with which China is embarking upon the other aspects of its world domination tactics. That 2021 will be worse for infections than 2020 is obvious. 2011 might also be the official declaration of modern version of WWIII (exorcise China from any trade, commerce at al from the world community, they would be certainly be welcome to trade with others of their voting bloc within the UNSC - Russia, Iran, Syria, Venezuela et al). U.S. Embassies around the world are currently enhancing security requirements for local governments (no more Chinese financed ports, public works, military/police operations etc.). 2021 might be the year when the Nerd will be cited more often so lets all prepare.
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David Rivard
12/7/2020 07:27:56 pm
The Body Politic
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Nerd has power
12/8/2020 06:07:16 am
Thank you, Guy, for sharing this article:
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David Rivard
12/8/2020 01:02:27 pm
With no certainty about both the origin and the science, our societies will continue to fight amongst themselves where there is no sense of a common purpose. If the scientific community at large were polled, they would agree that the synthetic thesis should for now remain open. They would agree that the synthetic option has not been openly debated, but has been censored in many forums.
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Nerd has power
12/8/2020 07:33:38 pm
David, your writing is cut short by the word limit here. Please continue. I have enjoyed reading this post a lot and I'm wondering how it ends :)
Peter Ross
12/8/2020 02:57:33 pm
So covid didn't work so the new fear-mongering strategy is 'chronic covids' and 'dormant covids' and 'wasting covids' and 'covid HIV'. Totally obvious.
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David Rivard
12/9/2020 08:49:42 am
No that's OK. I know my rant didn't contribute anything new but it was a little fun to write and I also appreciate everyone's eyes from a site I enormously respect. I was actually self-conscious about warping otherwise excellent scientific analysis as I watch you guys go back and forth. In the future I will be more moderate.
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Nerd has power
12/9/2020 10:06:42 pm
Thank you very much, David, for sharing your story and contributing to this forum. Your experience says a lot about the CCP. I'm sure others here would appreciate reading your post as well.
David Rivard
12/10/2020 11:14:51 am
Thank you. The most important thing I would like to convey is that your site is making a big difference and from my perspective a key difference. The professional quality of your contributors is evident and you can tell they spend their valuable time as truth seekers and patriots above all else.
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Guy Fawkes
12/10/2020 03:10:51 pm
Made the error of looking left & right while switching rocks the other day. Saw this:
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Nerd has power
12/12/2020 08:33:43 am
Thanks, Guy. Nicely put together. Yes, what a scary world we are living in. The advancement and approval of the vaccines are something quite extraordinary. I also can't convince myself that everything in there is science-based and public health-oriented. I don't know what the outcome would be with these vaccines, but I guess we are on the course of finding out.
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David Rivard
12/11/2020 10:21:05 am
Guy, I think that many find truth in what you say. And to think that all of these thoughts could have been avoided if an honest discussion about the origin were encouraged. If science said "synthetic" or even "maybe synthetic", then leaders could credibly say, "OK, we don't know if they fired at us yet but get these helmets on 'cause you're gonna need 'em". If you bellyache about the helmet they could credibly say, "You gotta go to war with what you have". I also think there are a lot of rocks to hide under but not many that have food hopping by.
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David Rivard
12/11/2020 10:33:30 am
The accurate way of saying it is, "We don't know if their coordinates are off but we're takin' incoming so get those ##1 #&*## helmets on!"
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Briran
12/12/2020 08:14:39 pm
Why Australian vaccine cause positive HIV test?? What about pfitzer vaccine?
Xoco Latte
12/14/2020 02:33:50 am
Re: Briran (WTF?)
Brian
12/14/2020 04:02:00 pm
I intend to agree with your positive thinking. I just lost my trust to scientific community which seems to be bought by big pharma these days. Just look at the nature papers from the origin of virus and now to selling vaccine.
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Peter Ross
12/15/2020 02:23:15 am
Maybe somebody has got a link to an exact description of the structure - polypeptide sequence, etc - for the Australian vaccine that was cancelled?
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Xoco Latte
12/15/2020 06:37:59 am
About the UQ-CSL V451 vaccine candidate:
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Xoco Latte
12/15/2020 07:01:15 am
As far as the "Molecular Clamp" technology goes, it seems as if the same molecular conformational stabilizer has been used in vaccines against H1N1 flu, RSV, ebola, Lassa, Nipah, MERS(!) etc. Interesting type of vaccines... especially MERS for which human-human transmission has yet to be shown to begin with (but 2019 emergency drills were all about MERS, maybe just an eerie coincident).
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Peter Ross
12/16/2020 04:01:29 am
Thanks kindly!
Peter Ross
12/16/2020 04:48:50 am
Another example -
Nerd has power
12/15/2020 08:32:48 pm
US Right to Know dug out another set -- email communications of Ralph Baric:
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Xoco Latte
12/16/2020 01:44:04 am
I tend to be not naive enough to expect these kind of so-called scientist to be stupid enough to write down their true thoughts in emails sent from official email addresses. They do communicate via burner mobile phones and personally without witnesses, just as members of similarly syndicated groups, i.e. mobs and cartels.
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Xoco Latte
12/17/2020 05:50:10 am
A November 18 BioAssays paper by Roassanna Segreto and Yuri Deigin on the laboratory origin of SARS-CoV-2: The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin.
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12/17/2020 12:02:17 pm
Xoco: RaTG13 has been debunked, so there is. O co troversy any more. Segreto is in my book “SARS-CoV-2: Contagion, Collusion, Corruption” (available from turningthetidepublishing.com and Kindle) commenting on the rare CGGCGG arginines that make up the furin cleavage site.
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Xoco Latte
12/21/2020 02:09:11 am
Debunked?
alex
12/17/2020 03:43:44 pm
Here Montagnier defends his version. New interview in France Soir.
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Frank
12/19/2020 07:21:00 am
But what about the new findings of SARS-COV-2 already in 2019 in France, Italy, and US? It looks like it was there long before Wuhan - or? I refer to e.g. https://www.news-medical.net/news/20201117/SARS-CoV-2-was-circulating-in-Italy-before-China-recognized-its-existence.aspx
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Peter Ross
12/20/2020 02:20:48 pm
what does it say?
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Nerd has power
12/24/2020 05:13:27 am
I think I have commented on this here. I definitely did it on twitter. Anyways, now that we know the reality of cross-reactivity of antibodies, especially those resulted from common cold (also coronaviruses), toward SARS-CoV-2, we should know how to properly judge such studies. That publication was not a convincing piece for me.
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Arnaud
12/19/2020 10:03:13 am
Again, about renaming BtCov/4991 :
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Peter Ross
12/20/2020 11:07:10 pm
Is this discussion off topic?
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Peter Ross
12/22/2020 09:58:55 am
Hurry up and get your DARPA ..er..'Pfizer'..cyborg upgrade shots to keep up with Chinas !
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Greg Felton
12/21/2020 02:41:41 am
Xoco Latte: RaTG13 has been debunked. Shi Zhengli and Peter Daszak both admit it is identical to Btcov4991, which was discovered 3 years AFTER the alleged RaTG13. Chapter 1 of my book shows this as well as other evidence. https://www.turningthetidepublishing.com/shop/sars-cov-2
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Xoco Latte
12/21/2020 08:16:31 am
Again, all the alternative theories about the laboratory origin notwithstanding, there is a brutal hegemony of peer-reviewed papers advocating or simply just accepting the natural origin hypothesis. In this scientific scene, peer-reviewed papers addressing the lab-origin scenario are more than welcome and necessary. I think one example is this Segreto and Deigin paper.
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Greg Felton
12/21/2020 11:49:33 am
If you're going to base your defence of RaTG13 on cognitive dissonance, then no amount of evidence to the contrary is going to make an impression on you. However, in the off-chance that it will, let me address the numerous errors in your last post.
alex
12/21/2020 08:57:22 am
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Guy Fawkes
12/21/2020 04:21:50 pm
Hello ALEX, @ [not yet peer-reviewed] preprints mentioning isolates of SARS-CoV-2, check those 3 papers:
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alex
12/22/2020 08:51:30 am
Thanks Guy, I will check.
Guy Fawkes
12/22/2020 12:41:02 pm
The recent Whitehead/Harvard/MIT-paper by Zhang et al. (2020) "SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome" is stirring up some otherwise peaceful spirits à la "If there ever was a preprint that should be deleted, it is this one!" over there on bioRxiv. Here the abstract:
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evidence
12/23/2020 08:30:41 am
Re: The equally deceiptful 'I am not a crook'-response of the Western science establishment in the context of the neo-Feudalism in the anthropocene era
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evidence
12/23/2020 08:33:05 am
And again: I doubt the frontline here is only between China in its bribed vassals on one side against the rest of us. This neo-feudalistic NWO (with new, prior unexpected sudden and corrupt alliances) is actually a very old one: feudalism has been the case for most part of human history, at least for his sedentary time. (In contrast: democracies, as well as dictatorships and facism had been rather brief exemptions in human history - all of them can only be constructed on quite egalitarian societies - which is not the case anymore for the West, and probably not for future China either.) What is new now, that this fragmented neo-Feudalism emerges globally in the context of the era of the anthropocean: naturally occuring old demons of the past we generate artificially by ourselves. Also, in that neo-feudalistic situation, evidence to be unearthed (so to speak 'the enlightenment') challenging the (social) status-quo sometimes takes a little bit longer, due to more powerful resistence - as compared to more democratic situations (a few more Gallileos have to be punished badly first) - but by in large, feudalism will be catastrophic for an independent science, i.e., science which would produce results beyond positivism.
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evidence
12/23/2020 08:37:26 am
I doubt that the same poll in any western country at any time until now would give such a clearcut outcome.
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Nerd has power
12/24/2020 06:08:11 am
Thank you very much for sharing your thoughts. I really enjoyed reading and learning them. I do agree that the interests of the Western elites (Wall Street, big tech, etc) are aligned with those of the CCP. It is a collaborative effort to weld a new order of the world with themselves fixed on top. In a way, this NWO is what you have described as the Neo-Feudalism.
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evidence
12/31/2020 04:03:08 am
Thank you! - Your response humbles me. But I also would like to respond to two specific points.
evidence
12/31/2020 04:06:16 am
2) Significance of U.S. national election. For decades, the U.S. NATIONAL election had been evolved into a masquerade, stealing the vote from the US-voter - it changes nothing in terms of rigging democracy and chronically disenfranchising power participation of its middle class, because: as we know, the 'winner takes it all principle' of the electorate (instead of proportional representation) is for centuries effectively barring any third party (= relevant extra-parliamentary opposition) from entering congress. (In likely contrast to single State elections, where proportional representation still largely works.) This situation is precisely intended so and this won't change.
David Rivard
12/23/2020 09:37:42 am
Greg, your important work is also a predictable part of the revolutionary tumult necessary to pull power from a comfortable, established asymmetric arrangement, in which a few (apparently corruptible) people control so much, into something more symmetric. I say predictable because a mutual global threat, both linked and networked, illuminates that the original advantage of “science”, the open global dialogue for all things as they rest on an “open” hierarchy of truths, where ideas can compete…openly with a global community, now no longer exists where it matters the most. Must we really have to re-live the “dare to know” age lastly challenged during the Enlightenment? The stifled global pressure to “know” (and know NOW when it matters the most), where both society and honest researchers are bearing down, is cracking apart formerly trusted publications under the mass on mass geometric progression of questions as they relate from all sciences (political, economic and biological). Now, there are tiny fractures that are causing a massive, maybe even fatal, collapsing pressure on these corrupted publications.
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Greg Felton
12/26/2020 01:03:24 pm
Thank you, David:
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alex
12/28/2020 07:43:12 am
Greg in your book you don't mention the Perez-Montagnier articles. not even Dr. Tritto's book, don't you consider them relevant?
David Rivard
12/23/2020 10:05:47 am
And hopefully this will bring them back to science.
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Peter Ross
12/24/2020 01:00:05 pm
Are people having fewer sex partners these days cuz coviditis panic?
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David Rivard
12/26/2020 07:58:22 am
I know y'all caught it cause it's making international news. Anyone know who the WHO invited?
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Guy Fawkes
12/26/2020 09:29:58 am
¡Hola! DAVID RIVARD, could you please elaborate for those of us living under massive stones, neither reading "the" news nor understanding Spanish? Inbetween the lines, am I correct that the mainstream finally catched up and got word of CoV-2 being some pimped gain-of-function Frankenstein? Imagine my shock. Thanks in advance, Sir!
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David Rivard
12/26/2020 10:18:48 am
Unfortunately not Guy. I got too wrapped up into Network Science in the way I would like to see it. There are still too many fundamentalists out there, particularly among the many partners of WIV listed previously, and headlines given by journalists trying for a gold star for the forehead:
David Rivard
12/26/2020 10:22:18 am
Guy, sorry that my translated version did not make it. You can use the translation option in your settings.
David Rivard
12/26/2020 10:31:19 am
Can international representative clinicians and epidemiologists access local clinical data to corroborate the lab tour?
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David Rivard
12/26/2020 08:03:42 am
A heralded announcement over a year after release.
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David Rivard
12/26/2020 10:05:13 am
It is still being deleted everywhere it appears:
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David Rivard
12/26/2020 10:52:17 am
Rep. Matt Gaetz (R-Fla.) is still on the trail and we should receive sources soon. I know you have all read this summation from April.
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David Rivard
12/26/2020 10:37:34 am
Excepting a few partners denying affiliation, recently:
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12/26/2020 06:26:39 pm
Hello everyone
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Nerd has power
12/27/2020 08:03:35 pm
Congratulations and thank you for sharing the link & info here.
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Peter Ross
12/27/2020 06:23:56 am
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Peter Ross
12/27/2020 06:33:07 am
What exactly is a "pandemic" ?
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Guy Fawkes
12/30/2020 11:14:45 am
Awesome summary PETER ROSS, your rhetorical questions are right on target - thumbs up and greetings to you!
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Guy Fawkes
12/27/2020 12:29:09 pm
Ho DAVID RIVARD,
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Nerd has power
12/27/2020 08:32:29 pm
Thanks for the tip at the end, Guy. The person that you saw walking in the woods alone with a mask on probably would not look funnier than the rest of us in the eyes of our future generations. I think it is inevitable that the future generations would see pictures and videos of our time and laugh at us. It's not just that we look funny. They must also consider the whole thing unbelievably ridiculous -- the whole world was kept away from the simple truth of the virus for a whole year, was made to believe a safe/effective drug useless and toxic, was offered (in some cases forced to take) rushed vaccines....... We will be judged.
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alex
12/28/2020 07:30:58 am
Do you know this article?
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Guy Fawkes
12/28/2020 07:04:18 am
You are welcome, NERD.
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David Rivard
12/28/2020 10:41:26 am
I think the one choice is very clear. Who do you want as the Imperial Empire? People need policing for the better or for the worse. People are monkeys and monkeys are animals. When Rome fell the western world plunged into the "Dark Ages" of cities fighting cities for over one millennia. The falsely vaunted world of eastern civilizations were really no better until brief spates of order, equally "unjust" were installed. During a great stifling period (sound familiar?), sciences of previous great imperial civilizations were only partially unearthed by the Enlightenment, but think of the continuum humanity lost. Castles and knights were symbols of survival, but we managed to romanticize this order too.
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Guy Fawkes
12/28/2020 07:12:43 am
Oh, the comment-function-dog ate the end of my little text, yet harnessing the power of the clipboard, here is it again:
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Nerd has power
12/29/2020 05:50:49 am
Interesting. Malik Peiris is an intriguing figure in the SARS-CoV-2/COVID-19 scheme. Why did he get involved in studying the temperature & humidity effect on SARS in 2011?
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David Rivard
12/28/2020 10:00:03 am
In case you haven't all read it, the forward thrust in Colin's important contribution "Plagues, Pandemics, Health Security, and the War on Nature" takes us back to some overarching questions we in the environmental community have been declaring since at least the 60's, even predating Rachel Carson and Paul Ehrlich ("if we do not limit our population, then mother nature is going to do it"...the original basis of the term "Sustainable Development" coined at the UNCED and now popularly used). Again, the most accredited scientific arguments were laid down throughout the UN Summit series of Boutros Boutros Ghali ("72 UN Committee on Human Development, '92 UN Committee on Environmental Development, Cairo Population Summit, City Summit et al). Resulting conventions, initiated by the environmental community and later represented by governments, were thus adopted into international and national legislation. We started with circumstantial convictions, largely based upon gut feelings and an intense love for both nature and the respective sciences we robustly lived. Colin articulates why "More pandemics are inevitable, but their severity can be reduced by greater transparency, international co-operation, and retreat from planetary boundaries" in a more scientific context than we could afford back then. The only real issue I had with the article, in the overtly stifled "scientific" environment (grants, publications et al) now more popularly revealed by C-19, in this age of information where the general public has more convenient access (remember staying at the library until 3 in the morning?), is editing the word "most" scientists to ""some" or "certain". I think this simple change would encourage the aforementioned transparency that he called out for better than we could have over a half a century ago.
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12/28/2020 11:43:30 am
Alex: Thanks for asking.
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Guy Fawkes
12/29/2020 11:42:29 am
CTRL+F tells me David Relman's PNAS opinion article from November 3, 2020 "To stop the next pandemic, we need to unravel the origins of COVID-19" did not trickle down to y'all so far, but I'm pretty sure he is a fervent reader of this little blog. Kudos! Nothing new for us nerdboys, but a neat, prudent résumé, check:
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Xoco Latte
12/30/2020 03:43:52 am
Thanks Guy, this is really a cautiously-worded opinion in the right direction.
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Guy Fawkes
12/30/2020 06:53:52 am
Thanks XOCO LATTE. Your snipplet is a truism. It's just that I opted on purpose for one in line with "Scientific evidence and logic behind the claim that the Wuhan coronavirus is man-made". I like that theme.
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David Rivard
12/30/2020 11:07:57 am
I know, I must also force myself to read articles having titles that abstract their intent, like "Lead investigator says no stone will be left unturned, although existing evidence points to a natural zoonotic spillover event". What does the journalist get out of such a title other than the virtue signaling necessary to get their article through the front door with a glance? Selling quick articles that only need to mention a safe source (Daszak – the accredited zoologist and self-acclaimed virology expert – through business). Remember that many of these “journalists” are in reality “at large” (but trusted) contractors. I even doubt that in bridging a credibility gap with Jeffery Sachs for readers at large (not necessary for publication editors), Sachs was ever directly consulted.
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David Rivard
12/30/2020 11:42:22 am
Clinical transparency can only show.
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Peter Ross
12/30/2020 06:07:03 pm
Ep104 - Vitamin D and Viral Special with Dr. David Grimes et al - Vital Viewing!
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Nerd has power
12/31/2020 09:07:32 pm
As nerdy as I am, I still feel the need to write something here on this last day of 2020. For whoever is still paying visits here and keeping this site alive, thank you. What a year that we had. And what the future is going to be? Some months ago, I told myself that there are two things that the world cannot tolerate any longer: communism and COVID-19. Yet, they are both still here :) I guess we will all have to continue to be distracted by these two. Hopefully the world can find a way to get rid of at least one of them in 2021. Fingers crossed.
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Peter Ross
1/2/2021 04:59:35 am
I have a feeling that c19 was a pre-emptive measure to vax the world against some nasty threat.
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Nerd has power
1/3/2021 12:08:23 pm
I believe otherwise. I think COVID is the real deal.
Guy Fawkes
1/1/2021 03:36:33 pm
A bird landed in front of my rock the other day, making a racket. A bird! Singing "LOC LOC LOC". LOC LOC LOC? WTF! Crawled out, took me some time to understand what all the chatter was about, then finally got it: LOC = lab on a chip. Now we are talking, and to be more precise - US patents. That's right ladies and gentlemen. US Patent 2017/0229149 A1 from August 10, 2017, check:
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Guy Fawkes
1/1/2021 03:42:37 pm
[...]
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Peter Ross
1/3/2021 04:20:29 am
A closer look at U.S. deaths due to COVID-19
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Peter Ross
1/3/2021 04:22:41 am
A closer look at U.S. deaths due to COVID-19
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Xoco Latte
1/4/2021 04:30:03 am
Alarming new developments with regards to the 'new' UK-variant B.1.1.7 with 17 mutations. Just like the pandemic has been restarted, now in Europe instead of China.
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Nerd has power
1/5/2021 04:45:44 am
To be fair, given the scale of the infections, mutations are going to accumulate. I think there has been more than one report where an immune compromised patient was monitored and the viruses within their bodies clearly accumulated mutations (not 17 of them though). Anyways, it's possible for this to happen naturally.
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Guy Fawkes
1/4/2021 07:00:28 am
Yo XOCO LATTE, good observations, good questions. Concerning UK mutations, check my previous excerpts out of Rambaut et al. (2020) "Preliminary genomic characterisation of an emergent SARS-CoV-2 lineage in the UK defined by a novel set of spike mutations":
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Guy Fawkes
1/4/2021 07:03:19 am
[...]
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Nerd has power
1/5/2021 05:35:00 am
Did some of the West politicians and other interest groups take advantage of the COVID pandemic? They certainly did. However, when you say "You never let a serious crisis go to waste", you actually admit that the ones taking advantage of a crisis might not necessarily be the ones who created this crisis.
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alex
1/5/2021 08:46:18 am
Nerd, Do you have any idea how they did it? How did they release the virus? and where?
Nerd has power
1/5/2021 12:51:12 pm
I don't know how they released it in Wuhan. What I do believe is that the first release was in Wuhan. The initial spread started there.
alex
1/4/2021 07:28:26 am
Minister Wang Yi says the origin is unclear and certainly not in China
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David Rivard
1/4/2021 11:12:35 am
Good analogy of WHO's Potemkin exercise. There were also a few since Catherine the Great, including Chamberlain visiting Hitler (CCP is Nazi is not far off). Who could execute such malevolence to humans, excepting those blinded by professional pride over pure science, or those executing a national expansionist plan in line with methodologies of previous empires? Collateral damage be damned, and cannot be factored into the purpose of this war. Already they talk about "leak" from a lab and not "synthetic" or not. If they affirm a lab leak I am sure they will be "sorry" it occurred. But the lack of sharing or discouragement of accurate information will always be directed at all collaborators, as Chamberlain was accused throughout history. After the weapon exacts its chronic wasting toll the world might finally develop an educated constituency for retribution.
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David Rivard
1/4/2021 11:29:38 am
Guy, Rom was just parroting the original author and purveyor of "You never let a serious crisis go to waste", which was both coined and practiced by Hillary Clinton through the Clinton Foundation. Ask any Haitian and they will confirm. If that seems too broad a statement then ask any of the Haitian National Police and they will confirm the arrest warrants out to anyone from the Clinton Foundation caught in the country. They are living in a world of consequences, soon to be joined by the aforementioned communities.
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Ruca
1/4/2021 12:47:08 pm
Hello! Only wanted you all to know about this book published in August 2020 in Italy: "Cina COVID 19. La Chimera che ha cambiato il Mondo" (China COVID 19. The chimera that changed the world, by Prof. Joseph Tritto). Unfortunately it's only available in Italian - at least for now, but here is an article in English and then an interview with English subtitles:
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Nerd has power
1/5/2021 05:14:47 am
Thank you for sharing these. I was aware of the news reporting Dr. Tritto's work. Glad that there is an interview in English. I can't agree with Dr, Tritto on all the details, but I appreciate his work in waking the world up to the truth that SARS-CoV-2 is a lab engineered virus.
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Xoco Latte
1/5/2021 08:11:47 am
A very interesting and perhaps a first phylogenetic study pointing towards the untenability of the theory of RaTG13 as the closest relative to SARS-CoV-2. What is even more interesting, it is from Chinese authors and it was published in Nature.
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Xoco Latte
1/5/2021 08:14:50 am
Shit, I wanted to cite a portion of the Summary from this report:
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Greg Felton
1/5/2021 11:11:22 pm
Even though my book on the man-made theory of SARS-CoV-2 is out, for which I am especially grateful to Nerd and his followers for their contributions, I feel I must respond to Nerd's comments on the CCP, in particular his allegation that it deliberately released the virus.
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Guy Fawkes
1/6/2021 04:57:11 am
false flag: a political or military action that is made to appear to have been carried out by a group that is not actually responsible
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Peter Ross
1/6/2021 09:11:26 am
Supposing China got punked by an adversary releasing the pathogen in Wuhan, how should China have responded differently?
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Peter Ross
1/6/2021 10:09:13 am
From 6 January 2020 - exactly one year ago:
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Peter Ross
1/6/2021 09:05:25 am
Luftvägspatogener
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Peter Ross
1/6/2021 09:18:11 am
Sweden has been criticized for neglecting to impose compulsory non pharmaceutical interventions (NPI) such as mask wearing, social distancing, school closures, and lockdown curfews, yet all of the major respiratory pathogens seem to have disappeared this flu season.
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Guy Fawkes
1/6/2021 02:05:55 pm
Ho PETER ROSS,
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Peter Ross
1/6/2021 05:55:53 pm
Yep.
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Nerd has power
1/7/2021 05:12:11 am
Greg,
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David Rivard
1/7/2021 09:06:27 am
So why would anyone take interest in participating in such a blog? Why not just get information from more popular scientific journals and media sources with faith? This site led me to many other sources that agree, or partially agree, with Nerd's premise, even though, like millions of others, I "know" that Daszak, Shi, GOF researchers, et al have our interests at heart. So do the wizened recondite's with grey beards who work as editors in Silicon Valley. WHO is certainly the global and honest broker for successfully combating the virus for the good of the world, even under the directorship of China's appointee. China's allies do not share information because they understand that China is just simply "being China". They are under no real mandate for transparency, either for the origin or the clinical manifestations are they?
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Xoco Latte
1/8/2021 12:17:39 am
Let's agree to diasagree here.
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Greg Felton
1/8/2021 02:13:45 am
Thanks for replying, Nerd. I appreciate it.
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Nerd has power
1/8/2021 06:13:47 am
Greg,
Guy Fawkes
1/8/2021 03:16:47 am
I'd like to chime in at this point & throw the first stone in the air in defense of NERD. I don't think he is dishonest, all to the contrary, NERD appears to be a very fine, upright gentleman [I presume "he" is male], my warm greetings at this point to him! Like everybody, NERD has his own story and cultural background, and it's always interesting of knowing WHO says something before looking at WHAT he says. I first thought NERD was from Taiwan, turns out he is from mainland China and it seems he now lives in the US. We don't know anything about how the communists treated his family nor the reason why he left China. But that should tell us enough about how he sees the CCP. Thus let's accept his position, we don't have to agree, as we walk in other shoes, right? Furthermore, I learned over the years to take info out of no matter which political camp, as long as it's beneficial to understand the mechanics of the world we live in. The ad hominem "he is on the wrong side, thus all he says is wrong" could not be further from the path of personal progression. So let's keep this in mind, aggregate some valuable infos here and merge it into our own, personal conclusions.
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alex
1/7/2021 09:02:55 am
Every day the Wuhan access of the WHO team seems more complicated.
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David Rivard
1/7/2021 09:35:37 am
There has never been an RFP or research without an "agenda". This for C-19, "Although a World Health Organization international team plans to visit China in early January to investigate what started the pandemic, its members and agenda had to be approved by China".
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Ron Hawkes
1/8/2021 09:55:12 am
I red a lot of this forum, the virology fleets me. But Quantum entanglement has successfully transferred information. I think that a chinese scientist potentially defected to the u.s with its 'Genomic sequence' (forgive my inept grasp on the science). Perhaps china knew this was imminent. i dont know if RNA or whatever is 'information'. If so then that could be done completely clandestine. There was some satelite that was found and covered up in china somewhere about 20 odd days after it was announced as a pandemic. The scientist that defected was a physicist i think. Im probaly wrong but i think there are 3 of these bio labs in the world, 2 in china and 1 is owned by u.s (bill gates foundation?) and 1 in russia. This is probaly heresy. To perform this entanglement requires a photon/light particle. Maybe lichen fungus as the surrogate, maybe not though. There was way more, but ive been reading this forum for bout 6 hours now, i wanted to contribute even though its stupidly radical. The people on here are far more educated than i, could this be plausible?
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Peter Ross
1/8/2021 11:20:28 am
Where it not for the non-specific and over-valued signs and symptoms used to discern between SARS-CoV-2 infection and other ailments, namely: "silent hypoxia", "impaired sense of smell", "ground-glass opacities", and "PCR positivity" - the year of 2020 AD would very likely have been recorded as the healthiest year in history.
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David Rivard
1/8/2021 12:15:04 pm
The problem the CCP has not pondered boils down to a rue of theories, and even truths, stemming from its constantly demonstrated opacity.
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Ron Hawkes
1/8/2021 12:17:25 pm
Yeah i figured, i mean live in new zealand. Life here has been pretty sweet. I enjoyed our little 1 month lockdown. I dont know of or heard of anyone catching it here personally.... Im convinced its malevolent... But fight the good fight though. If i find something worth posting with actual references i might try again. Loving the independent research going on. Fantastic.
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David Rivard
1/8/2021 05:10:53 pm
Yes, I am convinced that Xi seeks a quick shortcut to global imperialism, which necessitated breaking through this thicket of collateral damage, however historic. Such historic leaders have given more weight to their strategy and delegate tactics to those following orders. Collateral damages, even diplomatic, are not factors considered by the executors of tactics, much less the strategist. Such leaders consider and practice that any military and civilian prices paid are a conscripted patriotic matter, a price for the larger good, as demanded by The Strategy. It is a historic story that for many was accompanied by a similar denial of reality for those living it. As individuals we must conceive ourselves as being at the wrong place in history at the wrong time. Even trusted institutions can only stand by to experience irrelevance until they are replaced like the League of Nations. Guy would say, “Caught out from under their rocks”.
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Greg Felton
1/8/2021 09:12:52 pm
NERD:
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Nerd has power
1/9/2021 06:35:52 am
Greg,
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Greg Felton
1/13/2021 01:24:12 am
Yes, Nerd, I agree. We should let the viewers evaluate the evidence.
Nerd has power
1/13/2021 09:15:38 pm
Haha, great. I accept your perception of not accepting my perception.
Peter Ross
1/10/2021 10:37:44 am
Nerd, everything you say makes sense. But it doesn't rule out a psyop deliberately intended to look clumsy.
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Guy Fawkes
1/11/2021 02:40:58 pm
Geopolitical musings aside folks, check Haddad et al. (2020) "SARS-CoV-2: Proof of recombination between strains and emergence of possibly more virulent ones":
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David Rivard
1/11/2021 09:52:01 pm
Greg,
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Greg Felton
1/13/2021 11:20:28 am
I appreciate your comments, David, but it precisely because Nerd did NOT use “logical thinking and scientific evidence” to support his claim of deliberate release that I challenged his claim. To date, he has not addressed the circularity of his argument and thinks this is merely a difference of opinion, about “one truth” it isn’t. Without demonstrating a plausible motive on behalf of the CCP, he is not entitled to assert deliberate release as fact. That’s just basic logic.
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Nerd has power
1/13/2021 09:49:33 pm
Can't help to comment on your quest for motive here. On a court, you only need evidence to convict someone. You do not have to describe precisely his/her motive. There are people who never admitted their crimes and yet are still convicted -- it's evidence that really counts.
David Rivard
1/11/2021 10:06:13 pm
. The reasons they are hiding information, and not conceding as much as they can, has been deployed as a shell game which is akin to building mobile scud missile trucks and hiding them where you can. There would logically be several layers of denial when deploying a weapon, and it is stacking up against the first hurdle “synthetic or not”. I will maintain that by the time the world comes to the notion “intentional or not” the pandemic will have sufficiently limited our options, and for that matter China’s (but for their advantage). In other words the stakes could not be higher to arrive at a truthful conclusion. If not intentional, why is the CCP still not cooperating?
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David Rivard
1/11/2021 10:09:01 pm
and in preventing both morbidity and mortality. Don’t even ponder the economy and societal changes.
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David Rivard
1/11/2021 10:07:24 pm
and in preventing both morbidity and mortality. Don’t even ponder the economy and societal changes.
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David Rivard
1/11/2021 10:12:02 pm
and will protect the confidentiality and security of the Anonymized Data, in each case, in accordance with the Terms of Use applicable to the Global COVID-19 Clinical Data Platform. However, the problem in China’s case, is that the clinical scientist must submit their information to the appropriate – not state agency - but military department.
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David Rivard
1/11/2021 10:14:29 pm
Can we trust Chinese Covid-19 science?
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David Rivard
1/11/2021 10:18:27 pm
I hope y'all forgive my footnoting. Weebly's format does not take kindly to the standard word document reference format.
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Guy Fawkes
1/12/2021 02:52:55 am
NERDS: Can we plz get back into science, and away from reading tea leaves? If one of y'all is still not tired of dog-n-pony geopolitics, visit zerohedge.com et al. and you will have busy years of autistic reading in front of you. Enjoy the show, and then CU below some large rock as soon as tired from political bewilderment. But over here, can't we focus on something a lil' more tangible? Like... Cov-2-related publications in order to get an idea of how "intelligent design" was applied to it in some undisclosed lab? Here's something:
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Guy Fawkes
1/12/2021 02:55:33 am
‘Do you remember,’ he went on, ‘writing in your dia-
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David Rivard
1/12/2021 10:14:09 am
https://www.diplomatie.gouv.fr/es/el-ministerio-y-su-red/descubre-la-historia-y-lugares-emblematicos-del-ministerio/el-quai-d-orsay/
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Peter Ross
1/13/2021 04:38:39 am
People get offended easily so don't mention it's all an elaborate hoax.
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Guy Fawkes
1/13/2021 10:09:07 am
@DAVID RIVARD: I don't see it as a problem, but a predicament. And - as a natural scientist - I would claim that what we see here [an army of freaking lil' Frankensteins on the loose in their "wet lab", to cite Venkatakrishnan] are not even genuine scientific manifestations, but technical ones. Let me quote Ellul (1954) in "The Technological Society":
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Nerd has power
1/13/2021 10:34:11 pm
Excellent citation, Guy. I'm half asleep, but I think I like it a lot. How to resist survival in your scientific career? True question for people living in it.
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Guy Fawkes
1/14/2021 02:42:39 am
Thanks NERD, if you [or any other nerd over here] find the time for a digital timeout, read Ellul's book "The Technological Society" (1954) above [English language is misleading, as techne logos is only tech-talk, the French term "technique" or German "Technik" is all-encompassing]. One of the top 3 books I ever read. Ellul's "The Technological Bluff" (1989) is also a good one with fun chapters like "Technical Progress and the Philosophy of the Absurd", "The Bluff of Productivity" or "Terrorism in the Velvet Glove of Technology". And there is an oldschool-VHS-interview "The Betrayal by Technology" on YouTube with Ellul, check:
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Peter Ross
1/14/2021 10:52:10 pm
The damage from this FAKE PLAGUE is not from illnesses due to a novel infection but from the Lysenkoistic quarantine policies that paradoxically target the healthy population, incurring massive economic hardships, morbidity and mortality.
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Nerd has power
1/15/2021 05:15:01 am
Nature Medicine can't stop. Here is what it has recently published: a piece supporting the natural origin of SARS-CoV-2 written by the famous Angela Rasmussen:
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Guy Fawkes
1/15/2021 09:55:06 am
Dunno if everyone's humor, but I find it hilarious in relation to our lil' pet topic:
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TAKE DOWN THE CCP
1/15/2021 05:01:12 pm
U.S. Department of State just released a statement of CCP virus!
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Xoco Latte
1/16/2021 11:02:41 pm
... and there you have the officially annoited conspiracy theory - er, wait a minute, is this all true or that is what's called politically motivated diplomacy?
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TAKE DOWN THE CCP
1/19/2021 11:52:58 am
No need to argue with me. Stand out, show your identity and argue with the officials! Don't argue here like a coward with someone who is simply posting an official statement from the government!
Guy Fawkes
1/16/2021 06:41:02 am
What is said on RaTG13 is not new to us here, but in the following lies a good one:
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Nerd has power
1/16/2021 07:57:04 pm
"The WIV has engaged in classified research, including laboratory animal experiments, on behalf of the Chinese military since at least 2017."
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Peter Ross
1/16/2021 09:43:26 am
“WE'LL NEVER KNOW” IF CDN SOLDIERS BROUGHT COVID BACK TO CANADA | CONSERVATIVE MP BOB BENZEN
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Guy Fawkes
1/19/2021 02:52:47 am
@NERD@DOS: "'The WIV has engaged in classified research, including laboratory animal experiments, on behalf of the Chinese military since at least 2017.' Remember, ZC45 and ZXC21 were discovered in 2017."
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Guy Fawkes
1/19/2021 02:56:48 am
[...]
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Xoco Latte
1/19/2021 08:07:14 am
Hmm, I'm not sure I follow your logic in every aspect.
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Guy Fawkes
1/19/2021 11:21:57 am
@XOCO LATTE, please tell me where our respective logics fork, this is where it gets interesting, agreements are totally boring. Go for it, I'm all ears.
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Xoco Latte
1/20/2021 12:54:20 am
Dear @Guy, our opinion do not fork per se, my English seems to be not good enough to be sure I could follow yours. Sorry for that.
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Guy Fawkes
1/20/2021 05:18:03 am
@XOCO LATTE, you are more than welcome my man. Don't worry, language is only a vehicle to pass on ideas, it's all good. Just had a look at the paper again, they state:
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Xoco Latte
1/20/2021 06:14:58 am
Thanks a lot, Guy. I truly like your style and manners.
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Xoco Latte
1/20/2021 07:23:03 am
@Guy: do you think something like this what is under the water?
Guy Fawkes
1/21/2021 04:18:02 am
Thanks XOCO LATTE.
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Nerd has power
1/21/2021 05:44:28 am
Thank you, Guy and XOCO, for the interesting exchanges. I was not aware of the recent correction. Very interesting finding. It's strange to say to the least.
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David Rivard
1/21/2021 11:35:42 am
Will the WHO report mention how much un-supervised time they spend at the labs with their scientists and administrators vs. how much time at the caves?
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David Rivard
1/21/2021 12:02:28 pm
Twitter does not ban "conspiracy theories" vs. the U.S. @ https://twitter.com/Covid19Origin
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David Rivard
1/21/2021 12:23:26 pm
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David Rivard
1/21/2021 12:48:53 pm
CCP timing before the U.S. elections was impeccable. The question now becomes whether the DNC was either on the corner when the bus came by and unknowingly took advantage of the CCP's largess, or DOS DNC members had a driver on the bus. Either way the new govt. is demonstrating that it will conceal.
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Guy Fawkes
1/22/2021 04:30:09 am
Here the U.S. Department of State Fact Sheet, straight out of the Memory Hole, in its original layout:
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David Rivard
1/22/2021 11:20:36 am
Yep, and like the poet Robert White, must the URL repeat itself?
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alex
1/23/2021 08:24:57 am
What do you think about this?
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evidence
1/23/2021 12:14:59 pm
Re: Positive association between COVID-19 deaths and influenza vaccination rates in elderly people (C Wehenkel)
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Xoco Latte
1/23/2021 12:54:04 pm
I want to reflect only to the virus-immune system relation and the FCS insert apparent role in any effect on the host immune system.
Nerd has power
1/24/2021 08:53:21 am
Evidence:
David Rivard
1/23/2021 12:13:37 pm
As of this morning DOS has not determined U.S. policy re. origination.
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Peter Ross
1/23/2021 04:25:39 pm
Listening to this sharpened my perspective about this entire coronavirusopera, and in particular the wisdom of the early insistence upon a [presumably experimental] DARPA-style innoculation approach:
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alex
1/24/2021 08:20:31 am
Nerd, do you know this hypothesis that puts mink farms at the origin of everything?
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Xoco Latte
1/24/2021 09:51:10 am
Just my 2 cents.
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Xoco Latte
1/24/2021 10:14:38 am
One more thing that seems to be interesting to consider.
Nerd has power
1/24/2021 11:22:04 am
Thank you, Alex. I did not know this article. But are we surprised that another origin story emerging? There are so many ways we could debunk this one, but let's simply see which scientists these authors are trusting here:
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Greg Felton
1/25/2021 12:00:38 am
Nerd:
Nerd has power
1/25/2021 04:36:15 am
Yes, I actually read it two days ago. It's certainly a step in the right direction. We can keep an eye on how far they would actually go in revealing the truth to the public.
Brian
1/24/2021 10:42:14 am
Does this group has any insight on ADE as a side effect of vaccine described in several PubMed papers since october? Is it acceptable side effect that we can ignore or will cause more severe disease after reinfection. btw, Why severe disease in compare to normal vaccine?
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Nerd has power
1/25/2021 04:42:42 am
That is something that concerns me for sure. ADE is a known effect with SARS, and SARS-CoV-2 is just an enhanced version of that. So, I don't think we can easily rule out the possibility of ADE with these vaccines. I have read some articles and heard stories of reinfections leading to more severe disease in some people. Don't know how often it happens and what conditions are most correlated with ADE. There are just too many unknowns at this point, I think, that it's hard to draw a conclusion on ADE.
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Dave Atkinson
1/29/2021 09:53:24 am
The mRNA vaccines have been looking really good so far, maybe some mast cell destabilization leading to some anaphylaxis in vulnerable individuals. Otherwise, looking outstanding - J&J came up flat, Sinovac not so great, Astra Zeneca not that good
David Rivard
1/24/2021 10:57:12 am
I am sure PETA and donors @ http://www.petaasia.cn/ would love such a conclusion but I don't think they have balanced how many mustelids and other species have been tortured for GOF experiments...maybe several millions in Wuhan? How many mustelid lab deliveries for Wuhan.
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Peter Ross
1/24/2021 04:16:41 pm
The potential market for mRNA injections to improve the human body is limited until a 'pandemic' of economy-shattering lockdowns opens the flood barrier to FDA approval.
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David Rivard
1/24/2021 08:27:54 pm
Fox News (Steve Hilton) did a segment on the origin story tonight which seemed to uncover the first layer of the cover up (lab or not?). Still a major media, they threw the CCP a bone by inferring that this is simply U.S. and Chinese GOF research gone awry. They presented evidence of GOF research and outlined Fauchi and Dasak's role, but provided none for their conclusion that it was an "accident".
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David Rivard
1/24/2021 08:49:05 pm
Zhengli Shi and other names that appear on publications might have to be sacrificed too but it will be a comparative diplomatic bargain for the U.S. and China. Any other scientists or publications want to step up into this martyr's brigade with subsequent publication credit?
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Nerd has power
1/25/2021 04:54:45 am
People that are deeply involved have the risk of being used as scapegoats. This includes Zhengli Shi. To me, it's impossible that the CCP could get off this and blame it on a single person or two. But they also have demonstrated how brilliantly their media control works. To the general public, the truth can be buried, as long as they could work out a deal. In the long run, however, these people making deals on this would not look good in history either.
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alex
1/25/2021 03:35:44 pm
Check this please:
Xoco Latte
1/25/2021 12:23:00 am
Fresh from the preprint furnice Re: autoimmunity activation by COVID-19
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Guy Fawkes
1/25/2021 05:55:43 pm
Boy, that escalated quickly. I mean, that really got out of hand fast. Got 4 links to share:
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Guy Fawkes
1/25/2021 05:58:23 pm
#4@EVIDENCE, XOCO LATTE and others, check Wang et al. (2021) "mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants"
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evidence
1/26/2021 04:10:09 am
Re: Reply to [Nerd 1/24/2021 08:53:21 am] + [Xoco Latte 1/23/2021 12:54:04 pm] responding to my last post. For convenience and for having the reply button active, I am posting here.
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evidence
1/26/2021 04:16:27 am
Or more profanely: their primary concern probably had been at that time to keep it (there platform technology application) as simple and as convienent as possible to get Pfizer gigant and all its ressources on board - as SOON as possible. I think that would have been their chief concern. They were certainly cautious including allergic preconditions into the trials.
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David Rivard
1/26/2021 08:31:47 pm
Good analysis from evidence. It might have also been ordered out of the door due to the U.S. elections, when it would accomplish the most. Sometimes you have to go to war with what you have. The proactive discouragement of discussion from most quarters of science and media still has me taken aback.
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David Rivard
1/26/2021 09:36:20 pm
Also, if the new administration does not change "PHEIC" policies as a condition for re-joining the WHO (as the largest single contributor), among many other logical reforms
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Nerd has power
1/26/2021 10:16:57 pm
Great analysis, evidence. Thank you for sharing your thoughts here. Well balanced and reasonable. Yes, we favor different scenarios, accidental vs. intentional. Maybe this can ultimately be answered only with intelligence information or an insider's confession.
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Guy Fawkes
1/27/2021 01:38:09 am
@EVIDENCE:
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Xoco Latte
1/27/2021 04:08:40 am
Seems like the zoonosis tale gets a boost from US-French supported "research". Whatever that would mean...
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David Rivard
1/27/2021 07:45:01 am
Xoco Latte, I know it was somewhere in this string, but isn't there also 100% sequence similarity with infected Mus musculus and ferrets (or for that matter the whole family of any infected Mustelids) - or at least as communicable? Were mink farms infected through the workers? Again, there should be no reason NIH should not be disclosing their audit from taxpayer monies spend on this P4 lab, or any of them for that matter. Guy, spread the word to your neighbors that we'll start turning over stones.
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Xoco Latte
1/27/2021 08:50:10 am
I am sorry, David, perhaps I am too dim but I do not quite get your main point. Do you suggest that authors or some of their accompanies infected those Cambodian bats with the virus and after a successful infection the bat SARS-like virus was studied by them? Well, it's a very special logic but who knows. The 92.6% must be then a fabrication, since a human-bat transmission would not result in a difference that much in the sequence. Only a fraction of a percentage difference has been caused by adaptive mutations inside minks (OK, I know, minks are perhaps do not pressure the virus that much for adaption since the virus was arguably optimized in ferrets, well, anyway.)
David Rivard
1/27/2021 09:03:54 am
So, apparently NIH, nor any other U.S. government agency funded any "Eco Health Alliance" or Chinese GOF research?
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David Rivard
1/27/2021 09:15:40 am
Xoco, it's not what I meant but your interpretation was more brilliant than mine none the less...and opened up some new possibilities. My general forward thrust (that needed clarification) was that, "Is it true that the only 100% sequence similarity is with infected Mus musculus and ferrets?"
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David Rivard
1/27/2021 09:32:35 am
Again, https://www.whitehouse.gov/wp-content/uploads/2021/01/National-Strategy-for-the-COVID-19-Response-and-Pandemic-Preparedness.pdf
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Peter Ross
1/27/2021 10:27:55 am
So after a nine month ban, which included the fantastic fraudulant denouncements of HCQ safety perpetrated by JAMA, NEMJ and Lancet, medical societies are now endorsing liposomal/anti-parasitic drugs like HCQ to treat suspected coviditis:
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David Rivard
1/27/2021 12:15:36 pm
Our tiny Central American country has been deploying:
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David Rivard
1/27/2021 12:26:31 pm
An incontrovertible litmus test is US preconditioning before resumption of WHO funding. Particularly the Biden-Harris Administration's (yes, the government's websites all say Biden-Harris Administration and do not say Biden Administration") demands to admit Taiwan as a WHO partner before re-funding commences.
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David Rivard
1/27/2021 12:34:34 pm
So I would guess now that our main purpose on this site is to link the importance of origin to therapeutics and vaccine development (not to mention an obvious link to a serial killer's release of newer and more targeted strains), not withstanding my own deviations. Is that correct Nerd?
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Guy Fawkes
1/27/2021 03:04:13 pm
@XOCO LATTE: Had a look at the French paper, the Institut de Recherche Biomédicale des Armées (IRBA) was on board as a co-first-author. According to their homepage, one axis of research of the IRBA is "étude de la biologie des agents transmissibles pathogènes (menaces virales, bactériennes, parasitaires) et des vecteurs de transmission des maladies. Développement de contre-mesures médicales." As usual, no comment.
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Peter Ross
1/29/2021 09:27:24 am
Does the N95 virus-catcher catch all viruses or just the imaginary "SARS type"?
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David Rivard
1/29/2021 09:56:44 am
FYI
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David Rivard
1/29/2021 11:28:25 am
I still harken back to the way every nation keeps track of the virus. It is the WHO template:
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David Rivard
1/29/2021 01:09:16 pm
If you are a patient or attending HCW this is the data you collect:
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David Rivard
1/29/2021 07:57:45 pm
https://www.health.harvard.edu/blog/the-tragedy-of-the-post-covid-long-haulers-2020101521173
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David Rivard
1/29/2021 08:33:37 pm
https://www.medrxiv.org/content/10.1101/2020.12.24.20248802v2.full.pdf
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Greg Feleton
1/30/2021 02:25:18 am
Nerd: re Toronto Sun article:
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Nerd has power
1/30/2021 08:35:17 am
New Study By Dr. Steven Quay Concludes that SARS-CoV-2 Came from a Laboratory
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evidence
1/30/2021 03:13:41 pm
Even given statistically the odds are just overwhelming, from the logical point of view he found a few issues difficult to explain, cf. for example:
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Xoco Latte
2/2/2021 05:22:03 am
I agree, no serial passage after FCS insertion in Vero cells, but certainly in a cell line that does not confer purifying selection towards the loss of the FCS (human lung cells expressing or overexpressing hACE2).
David Rivard
1/30/2021 03:54:36 pm
Bayesian Network (BN) model is in vogue for C-19, I believe because of: information urgency + lack of facts (analyzed facts thanks to sites like this one) = BN model established hierarchy of truth to build upon.
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Greg Felton
2/11/2021 09:35:00 pm
David: Any talk of a "hierarchy of truth" necessarily implies a subjective frame of reference to determine what truth is, but that strips truth of any claim to objective reality. It is a solipsism. Twitter openly says that it censors posts that challenge the CDC/NIH narrative of the SARS-CoV-2 virus. Does that qualify as truth? It may be truth for Twitter but not for me or anyone else on this thread.
Xoco Latte
1/31/2021 05:09:17 am
I read it and there are some new (to me at least) points in it that further serve as evidential proof for the lab-made theory.
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Xoco Latte
2/1/2021 03:44:32 am
Well, the more I seek additional evidential support for this pShuttle-SN adenovirus "vector" vaccine claim, the more rebuttals I find in February and March last year. Really troubling, to say the least.
evidence
6/26/2021 05:32:29 am
Re: Adenovirus hypothesis basically outdated (Lyons-Weiler, Quay)
evidence
6/26/2021 05:40:33 am
(part 2)
Guy Fawkes
1/30/2021 08:46:45 am
@PETER ROSS: Are you ok, or simply trolling randomly? Not exactly sure about your standpoint these days, as you used words like "FAKE PLAGUE", "coronavirusopera" & "The imaginary SARS-type". Do you try telling the fine folks here there is no happy SARS-CoV-2 in the wild? And that we are all full retard to wear proper respirators in an appropriate context and should rather follow your example in dancing on the wrong wedding, telling guests there is no bride, ey? But wait, I'm sure it's just me and I did not get your humor inbetween the lines - or are you really one of those "the virus does not exist because it was never isolated"-luminaries? Well, then I'm sure you will highly estimate the following statement by the CDC, updated December 29, 2020:
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Peter Ross
1/31/2021 04:50:12 am
How can I know that the membrane particle with "spikes" in the EM is a SARS-type? How can I know if it's a communicable and virulent particle?
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Peter Ross
1/31/2021 07:03:20 am
How did all the other respiratory viruses disappear this season? Seems like this should be front page news:
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Peter Ross
1/31/2021 10:05:28 am
The PCR probes used to diagnosis "COVID" overlap with human DNA and RNA sequences:
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Xoco Latte
2/3/2021 03:47:51 am
Those pShuttle-SN vector sequences from some of the earliest COVID-patient samples might have been just lab cross-contaminations, after all. There were a few other contamination-proving data as well. Not looking good either. And I bet my whole family fortune on it that WHO so-called investigation committee will ask about these data first-place no-matter-what...
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David Rivard
1/30/2021 10:25:47 am
The WHO has a "fundamental commitment to provide information on health to all, in order to prevent ill health and to alleviate suffering. It is a vision of how to harness technology, health information, and education for the good of human development". If the CCP restricts the investigation in any way they would do better by themselves, the UN system and all nations to leave under protest rather than continue to blame China for their now perennial lack of facts.
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David Rivard
1/31/2021 09:57:10 am
Sorry about the lack of science in my posts, but in large part they are the popularized results of your posts.
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Peter Ross
2/2/2021 03:25:16 am
The probes and primers used in all the Corona PCR tests conform to multiple identical copies found within human RNA and DNA.
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Xoco Latte
2/2/2021 05:03:24 am
Effect of loss of FCS in replication, transmission and pathogenesis in vitro and in animal models. Published by the Galveston, TX BSL lab. Submitted August 26, 2020 - accepted Januar 13, 2021 -- meet the latest "accelerated" reviewing system at Nature...
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Peter Ross
2/4/2021 04:25:35 pm
Good choice of paper - haven't got through it all yet - there's an opportunity in it to compare the EM to the titer from same or different pellets and supernatent ; didn't notice if there's PCR to compare.
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evidence
2/6/2021 07:08:58 am
Re: Galveston Menachery group Nature paper on delta PRRA
Guy Fawkes
2/4/2021 12:16:17 pm
@PETER ROSS: I'm fully with you that a PCR-test magnifies contamination of a sample depending on which primers were designed, nothing more, and the more cycles [cycle threshold 40+ aka a one trillion amplification] it goes through, the more you will be able to exponentially magnify... contamination by "stuff". It's fun, a chemist once told me in lab that you will be able to find anything in tap water, any substance on Earth. Thus, imagine my excitement at all those false positive PCR-tests.
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Peter Ross
2/4/2021 03:57:50 pm
Is it just a bizarre accident that within the human DNA/RNA genome are found the exact same sequences being used for the probes chosen for SAR-Cov-2 PCR testing ?
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Peter Ross
2/4/2021 04:01:59 pm
Is it not reasonable to consider that the sequences for the PCR probes were chosen first and THEN used to design the SARS-CoV-2 genome?
Guy Fawkes
2/5/2021 07:09:22 am
I fully agree my man, perhaps the "missing link" between those bat-SL-CoVZC45 and bat-SL-CoVZXC21 was a human backbone, and/or a genetically engineered lab mouse with the "right" sequence that got used in order to create our favorite little virus.
Guy Fawkes
2/4/2021 12:24:55 pm
@ALL: At least, we, the bewildered herd, we have oldschool publications. What has been seen cannot be unseen, you know the cat meme. Here some classic pub archeology "for the record" of this blog, back from 2015 in Yang et al. [=Zhengli Shi, Ralph S. Baric & friends] (2015) "Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus":
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Guy Fawkes
2/4/2021 12:33:30 pm
Holy, sorry for triple masking folks, uh, I mean triple posting, the comment function is a tough cookie, here the last part of my autistic wall of words:
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Xoco Latte
2/4/2021 02:35:04 pm
The more I read and think about it, the more convinced I become that this has been a bi-phasic process where after an initial, slow beginning and perhaps an abrupt change in fundamental characteristics of the virus, a true epidemic started.
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Guy Fawkes
2/5/2021 07:11:29 am
One reason more to think this was not an accident.
alex
2/5/2021 08:49:31 am
confluence of influenza vaccines with localized releases?
Guy Fawkes
2/5/2021 10:23:28 am
@ALEX: What do you mean by "confluence of influenza vaccines with localized releases?" --> Do you refer to influenza vaccines used as false flags? Dunno, sounds weird, but everything is possible under the sun. Yet I would rather think of cross-reactions, check "Gregg Wolf (2020) "Influenza vaccination and respiratory virus interference among Department of Defense personnel during the 2017–2018 influenza season", I wrote about it before, use CTRL+F.
alex
2/5/2021 10:36:11 am
I was referring to what you just pointed out, but with the addition of possible releases in certain places.
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Peter Ross
2/6/2021 03:10:52 am
@alex @Guy Fawkes
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Xoco Latte
2/7/2021 06:38:21 am
A live, attenuated virus for vaccination purposes is, IMHO, anything but with regards to genomic optimization, transmissibility and infectiousness. A self-propagating vaccine requires a live and significantly attenuated viral strain, that causes very mild infection with very mild or no symptoms, infers average or strong immune response that lasts but initiates no multiorgan harm, and has a R0 between 1,0-1,5.
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Peter Ross
2/8/2021 04:24:58 pm
Good points !
Guy Fawkes
2/6/2021 03:27:04 am
There is a good one in The Lancet by Talha Burki from February 06, 2021, entitled "Understanding variants of SARS-CoV-2", quote:
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evidence
2/6/2021 04:10:44 am
Re: (1) Evolutionary molbio consequences with respect to judging FCS insertion and Cambodian bats
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evidence
2/6/2021 04:16:17 am
This evolutionary biochemistry aspect is actually quite often the reason in general, why there is such an extensively long protein backbone around relatively restricted, small and conserved, yet at the same time extremely crucial enzymatic (or like here: recognition) sites - that (the 'near vicinity') is always the interesting location where the relevant fine-tuning (=journey through sequence space) is taking place, ONCE the (enzymatic/recognition) function has become indispensable - in Monod's words, the 'chance' had become a 'necessity':
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evidence
2/6/2021 04:19:35 am
As David Rivard already has mentioned [in his reply to Nerd's reference to Stephen C. Quay's overwhelmingly powerful Bayesian method-based analysis (while about the adenovirus part I am not sure...)]: they might for example try to throw their own distorted Bayesian network calculations right on the market. Science fake news on a 'high' theoretical level coming from multiple sources, so to speak - that's what I would expect next. --- While the larger part of the established 'virology community', with relevant COIs would probably just be relieved, if the origin question officially remains UNRESOLVED for quite a long time to come. That's also most likely the main PURPOSE of the current WHO visit, given all the current pressure there is: keeping the origin question officially unresolved, so nobody can be hold accountable, nobody 'big' gets hurt, as in the same time this 'remaining unresolved' notion with an official WHO stamp on it likely also remains the ultimate long-term goal for the Chinese authorities on their public relations front (since the man-made hypothesis cannot be sufficiently discredited anymore by intimidation and information war).
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evidence
2/20/2021 12:30:33 pm
Re: (1) Characterization of S protein subdomains with respect to different mutational frequencies, including relevant implications for the FCS vicinity
Xoco Latte
2/7/2021 08:22:16 am
Thank you for the detailed explanation.
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evidence
2/20/2021 12:35:41 pm
Re: (1) Characterization of S protein subdomains with respect to different mutational frequencies, including relevant implications for the FCS vicinity
evidence
2/20/2021 12:39:18 pm
Of course, the edges of the S protein primary sequence (especially the N-terminus, but also C-terminus) might be well more pronounced in that diagram regarding AA mutation frequency, and would be noted first: they would be not my focus here, but I will also come back to that briefly below. However, the (broader) FCS vicinity remains discretely notable having a higher mutation frequency as well. That's my focus.
evidence
2/20/2021 12:42:36 pm
The first subdomains A-C (discussed below) belong to the S1 head on top of the protein quaternary structure, while D belongs largely to the 'collar' ('neck') at the bottom of the head and includes the FCS, (E) is functionally the 'stalk and hinge' region (as recently discovered by Turonova et al), while (F) likely the anchor in the virus (lipid bilayer) core and containing the C-terminus.
evidence
2/20/2021 12:48:10 pm
[part 4]
evidence
2/20/2021 12:52:45 pm
[part 5]
evidence
2/20/2021 12:58:54 pm
[part 6]
Peter Ross
2/6/2021 07:00:06 am
If you conclude from the sequence analysis (Segreto et al) that SARS-CoV-2 was most likely designed to serve as a self-spreading live-attenuated-virus for vaccination purposes - for example, as in an offensive or defensive biowarfare effort subject to accident, sabotage, or directed release (or a combination thereof) - then the absense of a co-existent infected animal population adds much confirmation.
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Nerd has power
2/6/2021 08:25:25 am
Peter,
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Peter Ross
2/6/2021 01:47:55 pm
Well, thank you kindly for taking a closer look at the assay. I'm trying to address internet rumours.
Peter Ross
2/6/2021 02:00:37 pm
Or maybe "RP" just stands for Cornpop !
Fuddman
2/28/2021 09:11:46 am
Mr. Nerd:
Nerd has power
2/6/2021 08:51:22 am
I want to share some of Daoyu Zhang's preprints. I know this one has been posted by Xoco and Guy, but it doesn't hurt to post it often:
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Nerd has power
2/6/2021 09:00:40 am
The other preprint from Daoyu:
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Nerd has power
2/6/2021 09:08:36 am
BTW, this publication was cited in the 2nd Yan report as well (reference 70). It was a preprint back then and is now officially published on Nature Communications. The finding is that pangolin coronavirus spike binds poorly to pangolin ACE2 (10 times worse than binding to human ACE2).
Nerd has power
2/6/2021 09:09:49 am
Forgot the link. Here it is!
Guy Fawkes
2/6/2021 12:10:52 pm
@EVIDENCE: "So, also with this knowledge in mind, the (wiv/pla) researchers might have had strong hints/very well been aware of the fact (maybe only eventually, e.g., after all the passages?), that the fcs actually could be working in domesticated/farmed organisms (lab animals as compared to wild live creatures), even when inserted into those respective wild bat progenitor strains (zc45/zxc21 and the like), as sellin had already pointed out (*), while in contrast very unlikely/not working so far in wild animals, bats in particular."
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Peter Ross
2/6/2021 01:53:32 pm
Yikes!
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evidence
2/8/2021 04:58:56 am
Thanks for the kind reply, and in particular mentioning (again) the important Kanduc publication !
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Guy Fawkes
2/6/2021 12:18:07 pm
BTW: By copy-&-pasting some cut off postings from above into Notepad++, I just figured out rocket-science-style that the maximum character limit at weebly.com is #5000.
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Guy Fawkes
2/7/2021 03:22:06 am
So it has come to this, nerds and girls - remember reinfections? There you have it straight, Andreano et al. (2020) "SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma", buckle up:
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Peter Ross
2/8/2021 08:06:49 am
So this virus can mutate in vitro on green monkey cells...and the PRESUMABLY glycosylation-modified particle is PRESUMABLY infectious and PRESUMABLY virulent in lab animals.
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David Rivard
2/7/2021 12:05:09 pm
Guy, the competent way you articulated that reminds me of thinking about our rationales when we look for spouses with attributes that we lack – “I’m hangin’ out with you ace because I ain’t got a clue” (Stevie Jankowitz with Kenny Powers). Move over from underneath that rock.
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David Rivard
2/7/2021 12:12:28 pm
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David Rivard
2/7/2021 12:14:59 pm
Sique,
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Guy Fawkes
2/8/2021 06:19:14 pm
Medical device? No
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Peter Ross
2/10/2021 04:48:25 am
So the filters, air being pushed out and sucked in, serve to concentrate virus particles which can easily be detected by examination of the filter after use?
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Peter Ross
2/10/2021 05:01:51 am
In fact, face masks are a highly concentrated source of all the respiratory viruses and other pathogens. And the longer the wear time, the higher the risk of contagion.
Xoco Latte
2/9/2021 04:53:17 am
Well, Nerds and Girls, this is just as comprehensive as possible at the moment... Whoa, kudos!
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Guy Fawkes
2/9/2021 01:41:12 pm
Totally awesome, thx for sharing, Xoco! It's fun to read about Mickey Mouse, exactly what I was suggesting some days ago @ the missing link:
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David Rivard
2/10/2021 09:57:15 am
I wonder how articles make it to publication with titles:
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David Rivard
2/10/2021 01:09:39 pm
And why does Nature continue to present such disclaimers? As a magazine they should submit their own paper about how they are maintaining a disclaimer that amounts to an editorial comment.
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Guy Fawkes
2/12/2021 05:35:42 am
@PETER ROSS: "[G]iven the imaginary [magnitude] of the pandemic" huhuhu, good one! Well given the completely pathetic masks especially children get to wear from their superparents, I suspect much of the virions happily pass straight through and/or around them and get sucked in, therefore you won't detect them as a fomite, Sir! Also, imagine a negative pressure mask comparable to those insect catcher nets aka they concentrate over time what does not pass right through. Therefore, after let's say a school "shift", if it's a really good filter, a lot of virions could be on its surface. Yet, what does this tell you about what the child effectively inhaled? Zero. As an analogy, it's like measuring alpha radiation emmiting radionuclids in Becquerel [Bq], which does not pass through the filter if it touches its fibers and gets stopped by 1,5cm of air or human skin anyway. What counts is the effective dose a human gets exposed to in Sievert [Sv] or Röntgen equivalent man [rem], it's the ionizing radiation in human cells that matters. The same is true for all virions which pass the mask/filter, be it not built to filter virions [like N95 or FFP2], be it mechanically damaged, or not completely sealed at its edges like all those cheap KN95 waste prodcuts. Hence, what's on your filter, Peter, does not matter. Ai?
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Peter Ross
2/12/2021 05:52:22 pm
Yeah - there's no detectable virus particles, or remnants thereof, on either surface of the face diapers.
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Guy Fawkes
2/16/2021 07:10:03 am
I don't suppose anything, Peter, other than a lab virus, which, to me, makes the most sense out of what we currently see.
David Rivard
2/14/2021 02:18:29 pm
Yes Guy,
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Guy Fawkes
2/12/2021 05:38:58 am
@ALL: Here a nice one from the archives - Lim et al. (2004) "Laboratory-Acquired Severe Acute Respiratory Syndrome", check:
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Babstar
2/12/2021 11:26:21 am
Guy Fawkes, a more recent paper with clear guidance on the current pandemic:
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Peter Ross
2/12/2021 05:40:26 pm
An ICU patient in respriaory distress is going ot be coughing up a lot of infectious particles, no?
Guy Fawkes
2/12/2021 03:13:44 pm
@BABSTAR: Awesome stuff, thank you so much! I rather wanted to point out @ 2004 for how long this corona-sniplet-saga already goes on. I like oldschool stuff, you know.
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Fuddman
2/12/2021 10:17:27 pm
Almost a year ago, now , the Nerd said this: "As of me, I am fully convinced that this is a bioweapon made by the CCP."
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Nerd has power
2/14/2021 05:39:41 pm
It is the unrestricted warfare that the CCP has been implementing. This concept might be new to people, but it is something the CCP has been engaged in and getting aggressive about. This bioweapon is part of that and is used to gain political advantage, not to cause casualty on a battle field per se.
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Fuddman
2/14/2021 09:04:13 pm
This bio-weapon released by the CCP has been wildly successful.
CC
5/18/2021 04:12:29 am
The unrestricted weapon aims at destroying one country's systems. Medical system, economic system, etc. No countries can control their people like Chinese government. CCP could lock you in your home without giving you food. This brutal behaviour could muffle the spread of the virus very quickly. But in west countries, governments cannot do this and people will revolt if they do. This is the advantage of CCP using this bioweapon.
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Peter Ross
2/13/2021 08:35:48 am
Consider:
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Guy Fawkes
2/14/2021 06:46:19 am
@PETER ROSS: Respect, now that's serious critical thinking, big up, I'm not kidding, Sir!
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Guy Fawkes
2/14/2021 06:50:45 am
#5 - Yes, now we know that even in the science world, the more "respected" a paper is [read: was], the more it's under political scrunity and they will publish uttermost bullshit under scientific disguise, something alike the famous "we dunno where it's from, but we 100% know for sure it's not coming from a lab". Boy, if only the Russians created SciHub in order to punish them. Wait, they already did.
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David Rivard
2/14/2021 12:35:04 pm
Peter, like myself, you have wandered into the deeper part of this tarpit of misinformation, or no-information, where we can find a few facts.The “unimpeachable” fact is that more and more of humanity chooses to join, and even cite, such sites to muck around in. If they cannot do that (credentialing or some technical reasons), they are increasingly talking in the streets or in their villages. Even if not intended as a war, it is a fact that the “Pandora’s Box” syndrome has come alive because of the lack of understandable and trusted information. Not the first time, we all know how unpredictable this era will get – and is proving to be.
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Fuddman
2/14/2021 09:51:13 pm
"It is because there is only one country, the most critical country, which has continued to unimpeachably withhold information."
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Xoco Latte
2/15/2021 12:14:18 am
Well, I honestly like the tone of conversation this past few days, especially since the COVID-19 'Committee' blatant lies came out and a new fabulous tale of origin started to be told (frozen meat). The media and some authorities (especially the WHO's AND the leader's of the Commettee) response to this has been quite surprising and multiplied the cacophony already surrounding the case.
Guy Fawkes
2/15/2021 04:58:17 am
Looks like - except from "INTERESTED ONE" and one of the authors himself back in September - it's a shame we totally missed Sirotkin K. & Sirotkin D. (2020) "Might SARS-CoV-2 Have Arisen via Serial Passage through an Animal Host or Cell Culture?", published in Bioessays back in August, quote:
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David Rivard
2/15/2021 08:14:44 am
But never underestimate large corporate media. Lots of kids out there need jobs:
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David Rivard
2/15/2021 09:02:49 am
That last link only about 3 hours old from AP and the Atlantic's self appointed intelligence committee. They want to issue another reminder that they are on the winning side.
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David Rivard
2/15/2021 07:08:37 pm
Guy,
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David Rivard
2/15/2021 07:15:07 pm
also another exoneration of a critically endangered genera, where all 8 species have been notoriously difficult to keep alive in captivity and have rarely bred
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Guy Fawkes
2/16/2021 01:42:48 am
@DAVID RIVARD: You are more than welcome my man. Some days ago, you wrote about funny titles, and "COVID-19: Time to exonerate the pangolin from the transmission of SARS-CoV-2 to humans" really is a good one. "Exonerate", like in "rehabilitate" or "aquit". I'm glad that pet made it out of of COVID-jail!
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Fuddman
2/16/2021 01:37:22 pm
"But as soon as the lab theory will turn mainstream [I suspect never],...."
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alex
2/17/2021 12:49:17 am
@fuddman,
Fuddman
2/17/2021 08:52:31 am
Alex: It might.
Guy Fawkes
2/16/2021 03:59:52 am
Gotta take an amused/bewildered look at the Moderna COVID-19 vaccine (mRNA-1273) slides from November 16, 2020. The Forward-looking Statements and Disclaimer are/is dotted with special gems, quote:
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David Rivard
2/16/2021 09:09:38 am
Hopefully this site can maintain the truth serum as it becomes available. When it bubbles up others who are actually employed to do it can use this catalogue for their distillation. We must keep the articles flowing and no thanks to my ruminations. Sequencing of this information might probably require Nerd to update his original paper. Easy for us to say. My extreme thanks that he has created this path and also some disciples.
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David Rivard
2/16/2021 11:26:03 am
Re. ruminations, I like to think of “next”, as probably most on this site are not employees that are directed what to do next and what to think next.
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Drastic
2/16/2021 10:14:32 pm
Was the virus patented?
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Xoco Latte
2/17/2021 05:12:56 am
The Frozen Food Fallacy (FFF) - I like this! FFP against FFF.
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David Rivard
2/20/2021 04:18:01 pm
Here is my scientific piece today:
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David Rivard
2/20/2021 07:53:48 pm
https://www.msn.com/en-gb/news/world/german-scientist-999-per-cent-sure-covid-leaked-from-wuhan-lab/ar-BB1dPo1K
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evidence
2/21/2021 03:18:30 am
Wiesendanger paper:
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alex
2/21/2021 03:03:04 am
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Nerd has power
2/21/2021 09:31:11 am
I can't read Dr. Wiesendanger's paper since it's in German. However, I must say that this is so far the only paper that dared to cite the two Yan reports.
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evidence
2/27/2021 01:59:07 pm
Re: France Soir articles (Jan 23 2021, Jan 29 2021) by Valère Lounnas/Gérard Guillaume regarding Yan reports
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david rivard
2/21/2021 11:26:07 am
If you convert to a word doc. then do a translation you will find it extraordinary. It can be more popularly understood and well supported. I hope it is not buried.
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Guy Fawkes
2/22/2021 02:42:33 am
@FUDDMAN: Indeed, Montagnier was shooting straight since his outspoken [quote: "un travail d'apprenti sorcier" = "a sorcerer's apprentice job"] interview on French pourquoidocteur-radio last April 16, 2020 - here the link again for those of you who understand French and missed it:
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evidence
2/22/2021 10:37:58 am
Re: Wiesendanger paper
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David Rivard
2/22/2021 08:42:48 am
In case ya'll ever ran across this article and momentarily got confused, this from:
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David Rivard
2/22/2021 08:59:17 am
And relatedly, and this is right up the Nerd's premise (go to "Lessons for Countering the COVID-19 Infodemic"),
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David Rivard
2/22/2021 09:17:16 am
And latest popular news from the less edited source Duck Duck Go:
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Guy Fawkes
2/22/2021 11:59:13 am
@DAVID RIVARD: Thanks, this medium-article is a perfect example for why I stopped reading "the news" over 3 years ago. Complete waste of time, there is never any long term benefit compared to a good book, and/or going straight to mutually cited scientific papers for "certain" topics we over here ***might*** share the same interest in.
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David Rivard
2/22/2021 08:26:35 pm
Guy thanks.I knew I could depend upon you for the great analysis. I wanted to cite this article because, as you said in better words than mine, this is as far as the analysis goes from "science writers for popular media". Hey, IC intern out there, do you have the picture?
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Guy Fawkes
2/23/2021 02:19:03 pm
Fascinating new paper by Kang et al. from February 17, 2021 "A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation" on loss+gain-of-function using CoV-2 and playing around with "a non-synonymous change (A1114G; T372A) within the Receptor-Binding Domain of the Spike protein". Granted, they used the obligatory congnitive dissonant & super annoying intro à la "[w]hile SARS-CoV-2 likely has animal origins" at the very start as a Schutzbehauptung aka evasive defence to secure future research $$$ and play the lame card, their results are nevertheless speaking for themselves:
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David Rivard
2/23/2021 07:42:40 pm
Biden Bans References to Chinese Origin of Coronavirus to Combat ‘Xenophobia’
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Guy Fawkes
2/24/2021 07:43:59 am
@EVIDENCE: Thanks for your comment on 2/22/2021, Sir! Sorry for not playing the reply-button-game, but I find it annoying to scroll and go fishing for other people's new posts, thus as straight punishment, I don't lead by example and put mine at the bottom.
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David Rivard
2/24/2021 09:16:29 am
Lessons from the past come to mind when you took us down memory lane. We might take another lesson about IC agency think from Retired CIA Director Woosley's new book about Kennedy's assassination in "The Agencies" attempt for redemption from the still many Kennedy conspiracy advocates out there. His good friend and colleague having recently perished from covid shares much of the corroboration. Accordingly, Khrushchev ordered the Kennedy assassination but the KGB called it off at the last minute. Knowing that their boss was off the rails, the KGB called it off out of their higher knowledge about the real repercussions (they later tried to cover for their boss - to his appreciation later). Oswald executed anyway, trying to appease his infatuation with Kruschev and evidently knew about dissention within the ranks of the KGB about the epic plot. He definitely had help, but from the KGB (can only imagine double agents et al). The illogical evidence presented to the public produced a logical direction for conspiracy groups to pursue, BECAUSE OF HIDDEN FACTS. The effect was that many blamed the CIA. The CIA/FBI IC community logically hid the facts because they had assessed that policy makers would be pressured into a nuclear war if the public knew (quite a stray from Thomas Jefferson's approach of "If the government shall have a discretion with the people, the government shall inform that discretion, not take that discretion away").
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David Rivard
2/24/2021 10:56:29 am
Just back up on the website:
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David Rivard
2/24/2021 11:05:52 am
https://www.wsj.com/articles/chinas-reckless-labs-put-the-world-at-risk-11614102828
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David Rivard
2/26/2021 08:37:26 am
OK, the last citation article is best for y'all, but the former articles follow a beneficiary timeline. What is evidentiary value? n. Law, the quality or authenticity of a record to provide legal or historical proof or adequate evidence. It is usually supported by circumstantial evidence.
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Guy Fawkes
2/26/2021 12:04:12 pm
@DAVID RIVARD: You are pushing the link-button hard my man. So what's your takeaway out of all those articles and videos - any new perspective you gained? I told you I'm oldschool, can't handle so much press from under my rock, blurres my mind. THX!
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Fuddman
2/26/2021 01:38:13 pm
"--> Batman, in both papers, is out. So where's the Joker? I did not read the NYT lately, thus critical thinking tells me there is a contradiction in plain sight here, as we have peptide sharing vs. ACE2-binding not in sync @ virions, humans, mice AND monkeys in both papers. I guess this leaves us with some genetically engineered lab missing Frankenstein blackbox link to fill the bat - XXX - human gap. Any suggestions, nerds?"
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Guy Fawkes
2/27/2021 12:48:43 am
@FUDDMAN: Thanks for your constructive suggestion/challenge! Cutesy language? Cutesy? Awesome, you made my day! You mean boring text is the way to go? Another sophisticated approach would be to scroll over anything you dislike, instead of telling strangers how to behave. But hey, I like your following sentence:
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David Rivard
2/27/2021 11:38:09 am
Well, yes anyway, sorry about the links, but
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Guy Fawkes
3/1/2021 03:55:13 am
@DAVID RIVARD: The short article by Col. Lawrence Sellin is outstanding. We wrote about his previous work - and background - before. In his latest piece you shared, he sums up the situation nicely:
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Peter Ross
3/3/2021 07:07:31 am
Most if not all of these lab animal experiments comprise eluents obtained not from a human source but from monkey cells as the intended source of infection. Thus, the eluent being studied should be referred to as "monkey coronavirus" and not "SARS" coronavirus, which refers to a pathogen presumed to be from a human source.
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Guy Fawkes
3/3/2021 10:01:41 am
@PETER ROSS: Thanks! I think the point Sellin made was that such transgenic humanized mice to "cook" your new coronavirus lab creations already exist for ca. 15 years now. And my point was that they might be the missing intermediate host everybody is half-heartedly looking for. Now to your question:
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Peter Ross
3/3/2021 04:17:49 pm
Refining through passage in humanized mice makes sense and as also passage in unwitting human subjects could be considered as a process for exerting selective pressures.
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Fuddman
3/3/2021 09:58:01 pm
The sun is asleep? Deep ‘Solar Minimum’ Feared?
Peter Ross
3/4/2021 01:44:36 am
@Fuddman
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Guy Fawkes
3/4/2021 12:09:28 pm
@PETER ROSS: Very interesting exchange. Yet I don't agree on your 2 last posts:
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Fuddman
3/5/2021 08:41:15 pm
As you suggested, I checked out the mouse model story.
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Guy Fawkes
3/6/2021 04:54:22 am
Thank you for having a look, Fuddman. "Postulating" is the right word. Indeed, it looks like a humanized mouse model was used to adapt the modified bat backbone in order not to leave any traces of the intermediate host. Hence the perfect adaptation to hACE2 since day one. In fact, technically speaking, we only saw the final result, as the adaptation took place in those poor mice.
Fuddman
3/6/2021 02:23:08 pm
"...a humanized mouse model was used to adapt the modified bat backbone..."
Guy Fawkes
3/11/2021 01:36:33 pm
Is this hard sarcasm, Fuddman, or are you asking for real? Not sure, because given your summary, you understood my suggestions @ 100%.
David Rivard
3/6/2021 11:45:19 am
We cited such publications on this site a few months ago, mas o menos. En vivo experimentation means expedited and purpose driven research with a targeted outcome. Normally, they are purchased from lab supply companies, usually each with their own patented mice. The usual application of such experiments are (purpose driven) therapeutics for Infectious Diseases, Immuno-oncology, Immunology and more.
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Guy Fawkes
3/6/2021 02:50:57 pm
THX David, indeed, the 1:1 match of the peptide sharing at the 7-mer level between humans and mice in Kanduc & Shoenfeld (2020) "Molecular mimicry between SARS-CoV-2 spike glycoprotein and mammalian proteomes, implications for the vaccine" is striking in this context. Looks like we now have a rather clear idea of what the steps were to create CoV-2.
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David Rivard
3/6/2021 08:02:31 pm
Orwellian, yes, wow. And here I just looked at the whole phenomena pragmatically like my neighbors on the south side of the border. CCP needed a shortcut to global dominance and influenced U.S. elections. Apparently the technological elite, still living under the influence of Star Wars, agree it remains a necessary, albeit sacrificial step for "humankind". Do they remember that their elite equivalents did the same to Rome, and when it collapsed so too did Western civilization for 1,000 years. They called it the "Dark Ages".
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Peter Ross
3/6/2021 08:02:06 pm
To make a long story short there is no virus.
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Peter Ross
3/6/2021 11:49:07 pm
THE LARGEST UNETHICAL MEDICAL EXPERIMENT IN HUMAN HISTORY
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David Rivard
3/7/2021 09:52:20 am
Peter, CCP is lovin' your analysis. It's better than sending scientists to caves or freezers, and if they can keep certain sectors of citizens meandering down other dead end caves, then "como no?" There is a consensus among the IC's about the lab origin the world over. Maybe consequential to this blog's first established pathway...and other independent explorers. Existing TPP partners, both state and private sector, are finally realizing that a Pandora's Box must always accompany schemes where many suffer and die and particular where collateral damages are never factored into a domination strategy. This accompaniment includes a box that digs deep, all the way to China. The authorization to release many such articles such as this is my proof (there are scores more).
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Peter Ross
3/11/2021 11:35:07 am
There is no SARS virus, you know that by now.
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alex
3/11/2021 12:33:00 pm
??
Guy Fawkes
3/11/2021 01:13:15 pm
Ok, and what about birds, Peter?
fuddman
3/11/2021 01:48:18 pm
You're not going to get anywhere pushing that "fakery" stuff.
Peter Ross
3/11/2021 02:37:49 pm
@alex @Guy Fawkes @fuddman
David Rivard
3/7/2021 04:16:43 pm
Here we go again with the popular citations. The "Why" seemingly subjective if not objectively analyzed (like not sharing any raw data, even clinical data, et al). Many popular articles are still in a current phase of subjectively dismissing the release was on purpose (an act of war) as an apology before they cite virologic evidence of synthetic origins. "No, it was not a planned release". And FYI, this is (still) the evidence the WHO Team used to dismiss the lab story,
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Guy Fawkes
3/8/2021 10:04:54 am
Very interesting new paper from March 3, 2021 on CoV-2 reinfections, by Choudhary et al. (2021) "SARS-CoV-2 Sequence Characteristics of COVID-19 Persistence and Reinfection" - from the discussion:
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David Rivard
3/8/2021 11:20:57 am
Politics plays such a pivotal role in where research dollars are directed. It is worthwhile to remind ourselves of the former state departments assessment below:
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David Rivard
3/8/2021 11:25:42 am
Today’s revelations just scratch the surface of what is still hidden about COVID-19’s origin in China. Any credible investigation into the origin of COVID-19 demands complete, transparent access to the research labs in Wuhan, including their facilities, samples, personnel, and records.
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Guy Fawkes
3/10/2021 02:54:47 pm
Looks like they were in serious bat caging mode over there in Wuhan, filing the following patent in mid June of 2018:
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Peter Ross
3/11/2021 02:38:18 pm
If you guys were really interested in solving the mystery of the latest seasonal flu syndrome, you would stop blaming a virus never shown to exist (fake virus).
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Guy Fawkes
3/12/2021 12:20:33 am
@PETER ROSS: Is this some kind of modern art? Peter, seriously, look via CTRL+F at what Fuddman just wrote on 3/11/2021 01:48:18 pm. Reposting the same, unfunded, ludicrous claim does not rise its alleged quality. Not sure what your intentions are, but if you really think CoV-2 does not exist, but the seasonal flu does [ergo viruses do exist, right?], well, what the heck are you doing in this obscure corner of the web? But I'm open to any new information radically changing my world view, so plz go for it! If you have some nice publications about "a virus never shown to exist", open the valve, post it! Otherwise, as Fuddman rightly pointed out, rather stick to the inherent theme of this blog and share infos supporting/discrediting a lab escape, that's what w are here for. If not, looks like you picked the wrong wedding, Sir!
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Peter Ross
3/12/2021 02:00:28 am
Are you worried about Covid syndromes?
Guy Fawkes
3/12/2021 04:43:49 am
Stay cool Peter. You meant 'symptomes'? I know a lot of people by now who got them and never fully recovered. Did you read my previous posts @ "the virus was never isolated"? That's oldschool Peter, got isolated a long time ago, do a CTRL+F for 1/30/2021 08:46:45 am and re-read my post. But of course, this does not fit into your argumentation line very well, that's why you ask again. See, I'm here to answer.
Guy Fawkes
3/12/2021 08:08:00 am
Let's move on and get back to science everybody. Here 2 "nasty" pubs. One about wastewater:
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Peter Ross
3/12/2021 10:15:51 am
Guy, as it turns out many of these "viruses" have never been isolated.
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Guy Fawkes
3/12/2021 12:52:31 pm
I get your point on voodoo science very well Peter, and I agree at 100%. Adding insult to injury, those shamans also created a voodoo creature as it looks like. Children playing with matches, this GOF-research is an infamy, see what happened.
Fuddman
3/13/2021 09:44:30 am
The recent notion arguing for Fecal/Oral transmission is not convincing to me. I'd go further and say the authors of such an idea are blowing smoke.
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Peter Ross
3/13/2021 03:28:57 pm
There is no transmission from person to person.
Peter Ross
3/12/2021 01:00:58 pm
@Guy Fawkes
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Peter Ross
3/12/2021 01:05:02 pm
@Guy Fawkes
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Peter Ross
3/12/2021 01:25:13 pm
@Guy Fawkes
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alex
3/13/2021 02:36:28 am
@Peter Ross
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Peter Ross
3/13/2021 06:16:03 am
@alex
fuddman
3/13/2021 04:50:55 pm
I don't understand your question nor what you say is a mystery. And I'd like to.
alex
3/14/2021 03:27:36 am
Yes, I am going to try, according to Peter the virus does not exist, so the question is, what is the objective of the CCP in saying that it exists?
Peter Ross
3/14/2021 04:30:35 am
@alex @fuddman
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fuddman
3/14/2021 02:08:53 pm
"It's a lot of work to fake pandemics."
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Guy Fawkes
3/14/2021 03:10:15 pm
What's a "fake pandemic", Fuddman? Or: What's a real one? Something "occurring over a wide geographic area (such as multiple countries or continents) and typically affecting a significant proportion of the population"?
Guy Fawkes
3/14/2021 09:24:52 am
People, it's getting psychadelic over here, and we really should not reduce ourselves - and this blog - to absurd levels à la
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Guy Fawkes
3/14/2021 01:51:50 pm
#2 PETER ROSS, you are classy, your posts a pure work of art, you pull no punches, I like your intransigent style. How sad we cannot sit around a campfire with some more buddies and enjoy a good Rhum Clément/Pan Tadeusz Przepalany Vodka/Woodford Reserve/Lagavulin [in that exact order], giving toasts to the spectacular achievements of scientific propaganda! That would be fun. Until then, tell me, how many layers of irony did you wrap around the following?
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Peter Ross
3/14/2021 04:45:56 pm
Nobody got infected through the air or the hands, after spending days together in the dorm room.
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fuddman
3/15/2021 01:58:45 pm
Mr. Ross.
Peter Ross
3/14/2021 10:01:52 pm
I imagine the German high court made sure to write that it's job is not to decide about viruses per se but whether or not a contract has been fulfilled.
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Guy Fawkes
3/15/2021 06:06:51 am
@PETER ROSS: You are right concerning the Nguyen-Van-Tam et al. (2020)-paper, this pesky incoluated group not able to infect others at the same level as the proof-of-concept study is an insolence! ;-]
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Peter Ross
3/15/2021 08:25:08 am
Sure, the dorm experiment used the wrong virus, amiright? Imagine that - all that work for what turns out to be a strain poorly adapted to the experiment...as revealed by subsequent 'deep sequencing'...
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alex
3/15/2021 10:16:40 am
@ Peter,
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Peter Ross
3/15/2021 11:02:58 am
It's only half true, or less than that.
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David Rivard
3/15/2021 11:04:15 am
These conversations do not seem to be advancing our thesis. Of course there will be vaccine wars (like China's 100% increase in vaccine material supplies, stealing information, trolling information et al).
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Guy Fawkes
3/15/2021 02:04:22 pm
Indeed David, I think by now, everybody got Peter's standpoint, let's agree to disagree and get right back to the theme of this blog - scientific evidence of lab manipulations of coronaviruses resulting in the creation of CoV-2.
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David Rivard
3/16/2021 09:35:57 am
OK! Getting back to business at hand! Peter, your interest in vaccines has relevance as well (why take the vaccine if C-19 does not exist?). Many have investigated the general patent picture that Guy has presented above. It would be worthwhile to investigate, through patent registration, the operational mechanisms of the Pfizer, Moderna, Astrazeneca, Johnson & Johnson, Sinovac, Sputnik, Sputnik? vaccines (reverse engineer the virus from the patents). The entire global scientific community has, for over a year, gotten used to hypothesis generating from reverse engineering, so some publications might even be accepted (albeit maybe just social media if you couldn't get some prominent partners to sigh (sic) on). It would even be valid to let your imagination get carried away from there.
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Peter Ross
3/16/2021 03:29:04 pm
In the winter season of 2010, many countries purchased but later canceled deployment of a rapid roll-out inoculation preparation based upon serosurveillance findings that many populations seemed to have asymptomatically acquired anti-Influenza A H1N1 antibodies during the 2009 summer-autumn:
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Peter Ross
3/16/2021 03:52:14 pm
Is Zero Covid Possible? - webinar
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David Rivard
3/17/2021 02:32:40 pm
Peter, many good points in the webinar.
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Dartagnan
3/17/2021 06:35:31 pm
Recently this Belgian vaccinologist Geert Vanden Bossche has been making some waves on the internet warning about how mass vaccination with the current SARS-CoV-2 S-protein vaccines has the potential to put selective evolutionary pressure on the virus and promote the emergence of new variant strains that could escape the vaccine induced IgG antibodies. While there are many issues with his claims, and he also seems to be peddling some sort of natural killer cell based vaccine technology, I was wondering what folks on here think about some of his ideas?
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Peter Ross
3/18/2021 03:59:01 pm
Fundamentally, there is no proof antibodies are directly involved during the acute course of covid, which itself is an ill-defined, heterogenous syndrome which has an average age of mortality equal to - or even higher than - the average age of mortality in general.
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Guy Fawkes
3/20/2021 01:33:50 pm
@DARTAGNAN: Very intelligent observations, Monsieur! Indeed, it will be interesting to see how long it will take until vaccines and PCR-tests will have to be adapted cat-n-mouse-style due to mutations rendering the initial versions outdated. This could be an eureka-moment for a minority, and the point at which others go depressed/apeshit. Cool to drink upstream the herd in any case, meaning the manifest empowering, early deployment of serious personal protective equipment is worth the investment - and with the realization a corona-vaccine-strategy is ill-fated, melancholy/violence only leads to even more melancholy/violence. Hence take your distance from mainstream confusions.
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David Rivard
3/18/2021 10:06:22 am
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Peter Ross
3/18/2021 12:57:14 pm
Retrovirology and microbiology are fields with high rates of premature deaths under suspicious circumstances.
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Xoco Latte
3/19/2021 02:19:57 am
In my humble opinion, this Mercury News piece is not more than a piece of shite. The only "evidential information it uses as reference is the "conclusions" of the WHO sightseeing tour. Crap.
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David Rivard
3/18/2021 10:28:47 am
https://www.foxnews.com/world/top-state-official-coronavirus-bioweapon-accident
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David Rivard
3/19/2021 09:30:59 am
Xoco, exactly. Another example how mainstream (but local) newspapers are force feeding their captives. If you are a dissenting but otherwise accomplished scientist you become an attractive addition on their list. There might actually be a case for libel in the way they are characterized. One can only assume that somewhere in the convoluted media board structures there are those voyeurs who will forsake all for their personal enrichment. Vlad the Impaler once impaled all of the "voyeurs" in his court because they were openly taking bribes to influence public policies from enemies of state. Vlad was also the first recorded ruler to use germ warfare, disseminating the plague among the Ottomans with success! The Ottomans, never understanding the origin of their disease, started fighting amongst themselves and became so self decimated they held Vlad's Kingdom off limits until many years later.
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Peter Ross
3/20/2021 10:27:39 pm
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David Rivard
3/22/2021 11:52:37 am
Bacillus influenzae is not a coronavirus. Focusing on a prophylaxis, or even treatments (that WHO is not coordinating) and calling it bad days does not advance the cause of science much less prevent future events.
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Peter Ross
4/7/2021 02:52:30 pm
@David Rivard
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Peter Ross
4/7/2021 03:05:00 pm
Acta Neurol Scand
David Rivard
3/22/2021 04:41:50 pm
The WHO report citations should not disguise sources of raw data.
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Guy Fawkes
3/23/2021 03:15:21 am
Here a new publication by Montagutelli et al. (2021) "The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice" about our favorite missing bat-human link [mice] and their astonishing receptor binding properties to CoV-2 mutants. I wonder if these represent lab "survivals/revivals", to borrow from sociology:
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Peter Ross
3/24/2021 07:29:59 pm
REVIEW
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Fuddman
3/25/2021 10:10:50 am
Very informative read. Made a lot of sense. By a guy from Atascadero State Hospital !
Toonewb
3/25/2021 08:23:43 am
Nerds and Girls,
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Guy Fawkes
3/25/2021 03:20:50 pm
@TOONEWB: Thank you very much for that paper! Convergent deletions & insertions for immune escape in such a short period of time should lift some eyebrows. In paleontology, the study of convergence of 2 or more unrelated fossil/modern taxa - over millions of years - is super interesting. Only take birds and bats as an example. As if putting your finger right where "God's work" was made, to paraphrase Goldman Sachs. So it has come to this, God's work in time lapse with CoV-2 variants of concern, quote from the paper:
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Peter Ross
3/25/2021 04:25:49 pm
Interesting experiment being conducted to see if synthetic RNA injections will function as S1S2 templates to invoke immune responses against "foreign" RBD ligands will prove safe from the standpoint of ACE2 associated exosome homeostasis:
Peter Ross
3/25/2021 02:56:24 pm
@fuddman - yeah, it's a funny-bone tickler to envision a forensic psychiatric facility where both inmates and staff cover up their faces in the same hijab hazmat attire for self-defense from those inanimate and invisible 'gene-hijackers' - rather than just unplugging the corporate-financed television programming idiot box.
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fuddman
3/25/2021 10:46:05 pm
Thanks for the utube link. Very interesting.
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Peter Ross
3/26/2021 04:32:58 am
yep. take it all with a few grains of salt :)
Guy Fawkes
3/25/2021 05:29:50 pm
A new article by Col. Lawrence Sellin "Location of Origin of COVID-19 Pandemic Identified – Between Two of China’s Biological Warfare Facilities in Wuhan" was published, quote:
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fuddman
3/26/2021 08:52:19 am
Score one big point for the "escaped from the lab" crowd.
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fuddman
3/26/2021 08:54:10 am
https://nypost.com/2021/03/26/ex-cdc-director-believes-covid-19-came-from-wuhan-lab/
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Guy Fawkes
3/26/2021 11:36:42 am
"'That’s not implying any intentionality,' Redfield said."
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Errata
3/26/2021 01:59:59 pm
The viewpoint that the coronavirus was built in a lab is gaining momentum and will soon dominate the consensus. This has been made possible by scientists willing to pick their battles and pretend that they believe it escaped by accident. They can be forgiven because they know it is inevitable that when a lab origin is agreed upon, whether it was an accidental lab leak or a malicious attack will be the next debate. Weapons for that battle are being sharpened but are for now kept sheathed. Lets look at the edge of the sword being brandished here.
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Peter Ross
3/27/2021 05:00:08 am
1. PROPOSED FORENSIC INVESTIGATION OF WUHAN LABORATORIES
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fuddman
3/27/2021 06:58:46 am
Conclusion to this very exhaustive attempt at relevance:
Craig
3/26/2021 08:38:12 pm
I recently saw a discussion about chickens and Marek's disease. The discussion pointed to the Marek's disease vaccine driving virus selection away from the vaccine causing more virulent forms of the virus.
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Peter Ross
3/27/2021 12:12:08 pm
Like chronic antibody titers used to diagnose HIV ?
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Question for you, Mr. Ross
Craig
3/27/2021 03:53:28 pm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516275/
Errata
3/27/2021 07:12:36 pm
@Fuddman: the question of whether a virus is alive or not is a variation on theme of the metaphysical question of determinism. If you are a determinist the answer is of course they are. If not then the answer is of course not.
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Peter Ross
3/28/2021 03:27:45 pm
@fudmann
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Guy Fawkes
3/29/2021 06:07:02 am
@FUDDMAN&ERRATA: Remembering what I learned in zoology/paleontology, life is defined as having ALL of the following characteristics in and by itself:
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Errata
3/30/2021 04:23:30 pm
@Guy Fawkes: Firstly let me thank you for your erudite contributions to the otherwise bland fodder I spend my evenings ruminating on. As to the definition of life, one must be ever on watch for the premises that lurk beneath definitions. They are no less dangerous than what lurks beneath rocks.
Guy Fawkes
4/3/2021 01:37:48 pm
@ERRATA: Hey, now that's a nice comment, thank you very much, Sir! So true @definitions & creatures below rocks. For the latter, always lift them with the opening facing away from you in order to give him/her the ability to run instead of biting you. Been there, done that, lesson learned.
Peter Ross
3/28/2021 04:11:25 pm
Finally, although much remains paradoxically guarded still as trade secrets, some of the GMO voodoo injection ingredients are coming to light:
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Guy Fawkes
3/30/2021 03:07:44 am
@PETER ROSS: You are totally right @ "some of the GMO voodoo injection ingredients", check out what's written in the AstraZeneca COVID-19 Vaccine Information for Healthcare professionals PDF:
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sangerventer
3/28/2021 09:07:01 pm
https://www.frontiersin.org/articles/10.3389/fmicb.2020.584717/full
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Fuddman
3/29/2021 05:22:40 pm
FTA "At the whole genome level, the sequence identity of SARS-CoV-2 is ......96% to that of Bat-CoV RaTG13 (collected in 2013 in Yunnan, China) (Zhang L. et al., 2020;"
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Errata
3/30/2021 06:30:14 pm
Sangerventer's post contributes because:
Guy Fawkes
3/30/2021 03:43:43 am
Addendum: To seize the "gist of this blog" as Fuddman rightfully put it, I'd like to point out the following observation:
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Errata
3/30/2021 07:01:23 pm
Gotta love these guys:
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Guy Fawkes
3/31/2021 12:56:06 am
Hehe, "high pre-existing binding ... mouse peptide mimicry". That's a true jewel Errata, congrats! Those humanized lab mice are sneaky, you will not catch them on a fact finding mission in the jungle. No wonder Bostickson & Ghannam (2021) wrote the following at the end:
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Guy Fawkes
4/1/2021 03:12:49 pm
Addendum: Talking humanized lab mice and the important paper by Segredo et al. (2021) "Should we discount the laboratory origin of COVID-19" Errata kindly linked above [with Yuri Deigin as a co-author btw], I guess it's a good idea to excerpt a little bit more out of the conclusion until the very end:
Guy Fawkes
4/1/2021 03:23:54 pm
Here a new commentary by Yan et al. (2021) "The Wuhan Laboratory Origin of SARS-CoV-2 and the Validity of the Yan Reports Are Further Proved by the Failure of Two Uninvited 'Peer Reviews'" from yesterday - I note the following:
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Nerd has power
4/1/2021 03:33:41 pm
You beat me, Guy!
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Fuddman
4/1/2021 09:18:50 pm
About your previous comment - "There we have it people, if one of you has an even more plausible scenario to propose about how this mess was created, please share. Otherwise, it begins to get boring."
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Guy Fawkes
4/2/2021 01:50:02 am
@FUDDMAN: Indeed, a sinister scenario, but not very practical. And talking ethics, I guess you don't have to look to other countries, consider this @ homo homini lupus:
Nerd has power
4/3/2021 05:30:11 am
I can't believe my eyes, Guy. If it wasn't the CCP, then why did the CCP fabricate all these viruses: RaTG13, RmYN02, pangolin coronaviruses,....???
Guy Fawkes
4/3/2021 09:30:30 am
@NERD: Hey, this is all finger pointing, not my style. Everything is possible. Yet I can very well imagine a sophisticated Chinese biowarfare program with some layers of plausible deniability as a cover story, in this case RaTG13 and the other "iterations". It's very possible the PLA worked on weaponized coronaviruses, as did/do the Russians and NATO-states in secret as well I presume. Like the atomic bomb, they all have it.
Nerd has power
4/1/2021 03:32:33 pm
Sorry for not showing up here lately. It's been really hectic. Don't know whether I missed any of your questions. If I did, I'm sorry.
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Guy Fawkes
4/2/2021 05:55:00 am
@NERD: Are you one of the co-authors again using a pseudonym? Congrats! One question in the context of the following paragaph of your latest piece:
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Nerd has power
4/3/2021 05:39:11 am
Dr. Yan's work on golden hamsters was done after the pandemic started (she's a co-first author of this Nature paper here, BTW). This knowledge was gained later, not before the pandemic. Yes, the CCP has money, but those CCP scientists apparently did not have this knowledge during their development and validation of the bioweapon.
Guy Fawkes
4/3/2021 09:01:49 am
So what does it mean concerning the humanized mouse model? Is this also your scenario of choice? Or what organisms do you think were used between those initial bat backbones and the final CoV-2 virus in order to fully adapt it to humans via serial passage? Cell cultures, humanized mice, hamsters... humans?
David Rivard
4/2/2021 01:49:46 pm
U.S. State Department replaced their (Trump Era) position paper on "coronavirus":
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Guy Fawkes
4/3/2021 05:33:10 am
Here an empowering info, as you might know my pet topic is personal protection equipment and how to decontaminate it. Check out Sagripanti & Lytle (2020) "Estimated Inactivation of Coronaviruses by Solar Radiation With Special Reference to COVID-19", quote:
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Arnaud
4/3/2021 10:39:22 am
@GuyFawkes you're not alone. Le link with the french institute has never been investigate. Especially the way they could share database. In the inserm images database, Vih1 is called 4991. What a coincidence Rabtcov/4991 became Ratg13...
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Guy Fawkes
4/3/2021 12:43:10 pm
Merci Arnaud! Du coup, je ne me sens plus tout seul avec ma petite théorie du sabot lancé dans la fine porcelaine chinoise. // Thanks to you Arnaud, I don't feel totally alone anymore with my little Chinese lab sabotage theory.
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Errata
4/6/2021 05:07:33 pm
Guy, your eloquence is done an injustice by your modest English translation of "sabot lancé dans la fine porcelaine chinoise." You do yourself an even greater injustice by doggedly waving the false-flag theory although it gives you an excuse to show off your astute recognition of the etymology of the word sabotage.
Guy Fawkes
4/10/2021 06:23:59 am
Errata, my point was not a 1:1 schoolboy translation, but to transfer meaning. And I'm sorry one does not throw a literal monkey wrench in French. Thus you are doing me an injustice by calling me a poser my friend, especially as you don't even know my native tongue.
Fuddman
4/3/2021 09:26:27 pm
Does COV2 deserve to be called a "Novel" organism?
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David Rivard
4/4/2021 11:22:15 am
Too focused on previous critiques and virologic evidence presented in the second Yan Report, I overlooked the key thesis, and one that I think deserves another bump to policy makers:
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Fuddman
4/5/2021 09:06:23 pm
The problem with YAN and, frankly, NERD is they keep up this never ending argument that the "Virus" did not originate in nature.
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Xoco Latte
4/6/2021 04:15:35 am
Hear, hear.
Fuddman
4/6/2021 10:41:26 am
I like this question Xoco Latte asks:
Errata
4/6/2021 05:18:40 pm
It has a furin cleavage site, therefore it is both engineered and a bioweapon.
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Nerd has power
4/5/2021 06:05:06 pm
Thank you, David, for citing this part of the 3rd Yan report. I mentioned about this book sometime ago in one of my comments.
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David Rivard
4/6/2021 12:55:50 pm
Like fuddman, I also liked Xoco Latte's "...what ....live animal models been used for testing?" Peter Daszak should have all animal shipment records, including who provided the lab animals, with their certifications and prices, as a part of his federal audit submitted to the grant makers. His own firm, in turn, is required to audit implementing partners for this public work before, and not after, they were paid. The grantmakers need these audits to conduct their own studies about how effective heir programs are (lessons learned et al). Peter, did you remember to include this information (the audits) into the WHO Report? You needed it to rule out the lab hypothesis.
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Errata
4/6/2021 05:59:23 pm
Recently from Yan et al. "As revealed in our second report, the scientific misinformation and cover-up by the CCP started before the initial outbreak, which indicates that the release of the SARS-CoV-2/bioweapon was not accidental but should be intentional. Evidence suggests that the outbreak should have originated from community tests of the bioweapon that went out of control."
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David Rivard
4/6/2021 11:51:53 pm
Thoughts; humans pose a greater flight risk than hamsters? They could readily acquire rodents that have not been fully humanized to eliminate the bellyaching? Lingual limitations? I know for a fact that rodents were excluded from international human rights protocols. I don't know of one NGO that advocates in their behalf.
David Rivard
4/6/2021 02:05:09 pm
OK, just today there are articles that will keep all interests going.
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Anthony Rose
4/6/2021 04:30:39 pm
Fauci's NIH founded and funded Wuhan. When gain-of-function research was banned, further funding was done indirectly.
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Fuddman
4/7/2021 01:35:47 pm
You started your post with this questionable assertion.
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Peter Ross
4/7/2021 04:58:28 pm
@Anthony Rose
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Peter Ross
4/7/2021 05:18:40 pm
You can find on the CDC website the fishy tale of 'reconstructing" the fabulous H1N1 of 1918 by stictihing together random strands of RNA recovered from a permafrost-covered graveyard in Cyberia circa 2000 AD.
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Peter Ross
4/7/2021 05:58:45 pm
@Anthony Rose
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Fuddman
4/7/2021 09:14:26 pm
@Peter Ross
Lois Gearhardt
4/16/2021 05:09:29 pm
Ahhh... Judy Mikovits. Please, do not fall prey to her claims. They will not check out if you decide to look. I got to know her personally in 2011-2014. I helped her with legal issues, or rather, I tried to. In the course of that, I learned she sabotaged the entire work of the R0 NIAID detection of MuLVs (xmrv) in Myalgic Encephalomyelitis (ME) aka Chronic Fatigue Syndrome) patients federal grants. The premise is sound, and ME is very real. ME looks like, walks like, talks like a retroviral disease, and progresses just like one, and it happens that it responds very well to ARVs - which not many people know and frankly, the feds don't want to acknowledge. There are marked differences in certain aspects from HIV, HTLV. Frank Ruscetti, whom I personally spoke with, did indeed find MuLVs in ME patients, long before the grant was awarded, and before Judy was spiking cell cultures with VP62. However, Judy, rather than have Dr. Ruscetti come work with the techs and grad students at WPI in Reno, which he would have done in a heartbeat, helped the Whittemores launch falsified "tests" for xmrx (MuLv), which netted them $3+ million the first year. A tragedy that never needed to happen. Judy controlled all the samples shipped to the other scientists working on the project, always culturing the samples with VP62 instead of providing aliquots of noncultured patient blood. I discontinued representing Judy, when I realized the labyrinth of lies she concocted about the work, about stealing the lab notebooks from WPI, then at a press conference with Ian Lipkin stating her work failed, it was "contamination" and so much more. I was able to put everything together after talking witnesses, reviewing emails, papers, reviewing legal documents and more. She told, and still tells, different stories to different people. She never followed through on any promises, any necessary action no matter how minor the effort to provide witnesses, evidence, paperwork she claimed she had. as a normal innocent person would. I also discovered her plagiarized her PhD thesis, from a better paper published many months before her thesis. Her cumulative and current spiels claiming Fauci tried to steal "her" HIV work, retaliated to get her jailed for stealing lab notebooks, that she was offered a Nobel in exchange for trashing the xmrv theory, that she cultivated hiv from patient 0, and so forth, are simply to keep her on the radar of people who don't know better and haven't compared her narratives in her "books" and her prior interviews to her ever escalating whoppers. If Judy had wanted to, she would have been privately funded by fans in 2012 to redo the ME/CFS study. She would not, because she could not-she cannot do the necessary bench work herself. What I am saying is, put no faith or credit in anything she says, and besides, it will change in a week. She was removed bodily from a flight in Santa Barbara when she became physically combative when an attendant presented her with a mask. The pilot asked her to leave, since she battered the attendant, she refused and the airport police had to pick her up because she refused to cooperate. She was arraigned yesterday. She has been telling several different stories about her arrest, including claiming it was caused by Fauci. Judy of late has been claiming to be a faith healer. Judy Mikovits hurt a lot of people, and took great advantage of patients and others.
Errata
4/7/2021 06:53:17 pm
This has been bumped:
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Fuddman
4/7/2021 08:33:05 pm
Thanks for the post.
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David Rivard
4/7/2021 08:26:05 pm
Yes, the past could have predicted the unimpeded C-19 clinical timeline as it occurs today:
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Fuddman
4/8/2021 02:58:02 pm
This article provides a different approach to the problem. And, at least to me, appears to provide plausible explanations for some of the unknowns which now exist. For example, what is the "source" of COV2
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Nerd has power
4/8/2021 03:52:12 pm
I would like to respond to an earlier comment made by Fuddman.
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Nerd has power
4/8/2021 05:54:45 pm
Talking about the understanding of the origin of SARS-CoV-2, this is what Nature just published. Again, please don't tell me that the world has all been brought to the same page. It does not seem to be the case yet, at least to me.
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Fuddman
4/8/2021 10:42:14 pm
In my humble opinion, you have done a superb job of proving COV2 is fake. My hat is off to you for that.
evidence
4/12/2021 04:26:47 pm
Congratulations to your 3rd Yan report!
Errata
4/10/2021 01:30:24 pm
Nerd, you sound despondent. Cheer up! The tipping point is near. The Chinese choir still sings loudly but the congregation is falling away. Your evangelizing is winning converts. Politicians follow the people. You will win. Your victory will be sudden and dramatic.
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Nerd has power
4/11/2021 05:55:39 am
Thank you, Errata. I enjoyed learning your assessment of the situation, and I agree with it too. WE are winning and WE have to win.
PETER ROSS
4/9/2021 04:14:55 am
@Fuddman
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Fuddman
4/9/2021 09:51:15 pm
I listened to Nick Hudson on YouTube.
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PETER ROSS
4/9/2021 04:28:36 am
Thoughts?
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Fuddman
4/9/2021 01:48:04 pm
Here is a thought.
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Fuddman
4/10/2021 09:34:11 pm
Additional thought on the study you cite
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Errata
4/9/2021 04:02:18 pm
@Ross: Virus sequences derived by lab techs around the world testing samples from patients hospitalized with pneumonia are all fraudulent? There is some sort of lab worker conspiracy to deceive the world? That is not even remotely plausible. Nobody believes that. You do not believe that.
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PETER ROSS
4/10/2021 03:37:00 pm
@Errata
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Errata
4/10/2021 06:56:40 pm
Rodents are fine. Rodent models may have their limitations but those who use them are aware of it. Transgenic strains can overcome that to a great degree. But as Yan pointed out, golden hamsters are a better fit for work on corona viruses. For their advantages many types of animals are used in research but they are generally more expensive and less available. Furthermore there are the objections of the animal rights community which are muted somewhat in the case of rodents. Rats and mice are generally seen as repugnant so their lack of a fan base is a significant advantage.
Errata
4/10/2021 11:16:47 am
@Arnaud: Wearing even the most rudimentary mask in public helps protect those around you. The premise of this "little wink" is that no individual has an obligation to modify his behavior to promote the wellbeing of his community. It is a variation on theme of the mantra of the progressive movement. Any society that lives by this principle will die by it in a bioweapon war. We are currently in a bioweapon war. Too bad about the French, hate to see them go.
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Arnaud
4/10/2021 01:56:52 pm
The "well-being" is already durably compromised in France, and this not because of the Covid desease. Any child should never be considered as responsable of the oldest health. But it was just a wink in this very serious discussion.
Guy Fawkes
4/11/2021 02:54:36 am
Sunday-reading for those interested: "The SPARS Pandemic 2025-2028: A Futuristic Scenario to Facilitate Medical Countermeasure Communication" by Brunson et al. (2017) at the Johns Hopkins Center for Health Security, Maryland, USA:
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Fuddman
4/11/2021 12:42:43 pm
The lead "scientist" in your Sunday morning read is a person by the name of Monica Schoch-Spana (Monica for short).
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evidence
4/19/2021 02:02:49 pm
Re: Pandemic prophet - the other way round -
Arnaud
4/11/2021 06:19:26 am
France uses a very repressive way to control lockdown and limit individual freedoms. Perhaps France is the country with the most to hide? remember the inserm database picture Vih-1 ref 4991
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Guy Fawkes
4/11/2021 12:42:10 pm
NERD, this time, it's me who cannot believe his eyes:
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Fuddman
4/11/2021 12:52:11 pm
Oh come on!
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Xoco Latte
4/13/2021 04:15:33 am
Dear Guy,
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Potaytoes
4/13/2021 07:05:50 am
Guy,
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PETER ROSS
4/13/2021 12:39:47 pm
Yeah, the USA has always been part Grande Illusion, never actualy relinqusihed by the Brisitish East India Company subversions, and with a eugenecist SnotSea deep state comprising among others: Vril Society/Skull&Bones/Standard Oil/Ford/IBM/Schroeder Bank/Sullivan&Cromwell/Prescott Bush/Dulles/Kissinger that financd the 3rd Reich and arrnged for the global regrouping of this Borman Brotherhood of Isfahan, -Permindex, Knights of Malta, Stasi, Interpol, United Nations Orgnaizatrions, Vatican Bank, Red Commies, White Russians, Banderistas, Peronistas, Bathists, Nasa Space Nazis, CCP, Bilderberg, Free Masons, Scottish Masons, Albert Pike, Walt Disney... or whatever mkUltra aliases they use. Operation Kissinger Paperclip - probably close to a 100,000 former SS recruited just for Clowns in America.
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Xoco Latte
4/12/2021 04:25:05 am
An interesting quasi-research paper published in preprint a few days ago entitled "Who funded the research behind the Oxford-AstraZeneca COVID-19 vaccine? - Approximating the funding to the University of Oxford for the research and development of the ChAdOx vaccine technology".
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Fuddman
4/12/2021 08:52:43 am
"...it is quite nice to see that University of Oxford stipulated that ChAdOx vaccine should be sold on zero profit price to any countries and, even licensed to India under very beneficial terms as well."
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David Rivard
4/13/2021 10:25:10 am
Great analysis from Errata. Although saddened by anyone’s departure from this post, we should have taken his constant reference to crawling out from under a rock to an analysis. He and I had a lot in common. We rode MTB’s and read the same books, and for a time in my life, I even once worshiped virtually all of the authors he cited…and I acted on their findings! These “counter culture” authors had a sense of why the U.S. should change at a time when the entire world was worried about mass famine in China. Indeed their ruminations probably contributed to global policies that enhanced China’s standing, albeit while still vilifying Russia.
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David Rivard
4/13/2021 11:28:10 am
All aspects of the pandemia must be dovetailed into the "spectacles" science needs to determine source and projected outcome.
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PETER ROSS
4/13/2021 12:01:49 pm
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PETER ROSS
4/13/2021 04:24:41 pm
FYI
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Fuddman
4/13/2021 09:25:19 pm
The authors of this study spent a lot of time and money to cast doubts on the the Chinese claim COV2 is real and exists in nature.
PETER ROSS
4/13/2021 01:45:39 pm
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Lois Gearhardt
4/16/2021 05:30:00 pm
I apologize for barging in... I was reading, have been reading, much of the fascinating discussions here. My question is wrt discussions of the furin cleavage, etc. My understanding was that the amazing efficacy of the ccp virus' infectiousness is due to having HIV proteins, as well HTLV 1&2 CRISPRed onto the spike (the Indian lab first found this Montagnier also). Discussion of hiv proteins suddenly became "furin" almost immediately in 2020. I bring this up also because Australia stopped with implementing one of the shots, because it was causing "hiv false positives." I wish I had my sources at hand, but they said they didn't want to public o lack confidence in that shot, what with the hiv positives happening. Later I read, that there were so many hiv positives, that the followed on with CD4+4 counts, and aha, the positives were not false. The study controllers decided that they would ascribe hiv infection to the afflicted having acquired hiv during the two week interim period around administering the jab and follow up. The jabbees were not happy because they were not engaging in high risk behavior. Something was done, as the jabbees have not spoken out, perhaps they cannot or settled? That's vague, and why I wish I could find my stash of articles and snippets. If the jabs are made to ramp up production of the spike proteins, Anyway, my understanding from reading other articles, papers on the conformation of the furin arrangement, what makes the virus "novel" is that hiv furin cleaving does not occur anywhere else in nature besides siv, hiv and ccp virus. Please, no ad hominem. .
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PETER ROSS
4/13/2021 04:31:08 pm
Considering the Covid Syndromes from Toxicology POV:
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Fuddman
4/14/2021 10:23:17 am
Is the RT PCR test dangerous?
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David Rivard
4/14/2021 11:28:15 am
Links to the 3rd Yan Report,
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Fuddman
4/14/2021 01:57:49 pm
I'm beginning to be suspicious of Ms Yan.
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Deadly??? Truth is that if you have a look on mortality rate and life expectancy all over the world, all the pandemic is a very big fake news. Do this exercise seriously during a few minutes. Don't just focus on Covid death count. All this can be ended just now if there is a common wish. It's up to each of us.
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Limeng Yan
4/18/2021 08:02:53 pm
Hi, Fuddman, Thanks for your comments on my reports. However, may I ask when and where I suggested SARS-CoV-2 is “very deadly” and support lockdown?
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nonameneeded
4/14/2021 10:14:40 pm
https://www.pnas.org/content/117/41/25254
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Xoco Latte
4/15/2021 05:21:36 am
As far as the superantigenic motifs within the spike protein go, there is more and more supporting evidence from recent publications. As the haplotypic differences between Caucasian vs African vs Asian races ar involved, there less evidences although the striking difference between pandemic deaths in Asia vs North America and Europe speaks great lengths.
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nonameneeded
4/15/2021 07:01:09 am
I am actually a clinical immunologist and working in basic virology (would not quite call myself a virologist) and am kind of shocked at how I didn't pick up on this sooner. I had attributed the hyperinflammation to a generic T cell lymphopenia (which other coronaviruses have caused) leading to uncompensated viral-induced innate/monocyte driven inflammation - akin to infection-associated hemophagocytic lymphohistiocytosis.
Errata
4/17/2021 05:05:23 pm
@nonameneeded wrote(4/14/2021): "it is worth looking at whether the SEB-like motif in SARS-CoV-2 is optimized or deoptimized for certain ethnic groups. If the rumors are true, a virus that targets European or African haplotypes or T cell receptors over Asian T cell receptors could fit within the 'ethnic bioweapon' paradigm."
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Limeng Yan
4/18/2021 08:35:50 pm
Hi, nonameneeded,
nonameneeded
4/18/2021 08:58:20 pm
While vaccination is optimal, a bioweapon release does not mandate such in a society like China were the authorities knew the level of control could be brought to bear to eradicate the infection through brutal quarantine, lockdowns, remote monitoring, etc. Furthermore, widespread rollout of a vaccine before a pandemic would have been impossible to conceive and would be proof positive of nefariousness - both to their own citizens and the outside world.
evidence
4/16/2021 06:06:55 am
Re: 1) Super-antigenicity of extended PRRA stretch with putative Moderna patent sequence included
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evidence
4/16/2021 06:13:32 am
Hence, the IMMEDIATE DESTRUCTION via syncitia formation of VULNERABLE tissue (lung, small vessels), while the virus is budding and transfecting adjacent cells, is far more severe in CoV2 as compared to SARS1, specifically due to the FCS - likely resulting in a way stronger immune response (cytokine storm), particularly as soon as CoV2 has invaded inner organ tissue with vulnerable architecture (and the super-sterile blood vessel compartment in particular) - which subsequently also results in stronger coagulation effects as soon as endothelial cells are involved and compromised, as they form likely likewise syncitia, and by doing this, get more strongly inflamed/induce a way stronger inflammation response (as compared to SARS1), and subsequently stronger coagulopathy effects.
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Davd Rivard
4/16/2021 09:45:37 am
OK, I am all ears. Being in a small country with an unusually transparent President who has meticulously shared data and competently managed covid events, we took the Pfizer vaccine in order to travel. Like individuals and small counties alike, you choose to act pragmatically. My wife and I looked at one another other and said: "Now we can buy 5g phones!"
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David Rvard
4/16/2021 10:06:57 am
The government treatment, which includes Ivermectin, acetaminofen, aspirin, zinc and an assortment of vitamins, is delivered in a box to anyone calling in with symptoms (maybe relevant to research). It has a reported near 100% efficacy if taken within 3 days of symptoms. Citizens are urged to also check oxygen saturation levels and report if under 95.
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Fuddman
4/16/2021 02:21:42 pm
The thinking of the posters on this blog seem bizarre to me.
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Errata
4/17/2021 03:24:48 pm
@Fuddman: "It strikes me as odd when posters talk about the characteristics, consequences and vaccines for an organism, COV2, which the author of this blog has proven does not exist."
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David Rivard
4/17/2021 10:42:23 am
It occurred to me that a part of the public hesitancy with covid vaccination (outside of a previous but small legacy population against vaccination of the U.S. public), is perpetuated by the CDC website itself. Despite strongly recommending vaccination to more quickly achieve "herd immunity", even in the face of variant infection, "Coronavirus Vaccine Update From the CDC With Nancy E. Messonnier, MD",
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Errata
4/17/2021 04:30:57 pm
These are not necessarily mutually exclusive. Dr. Yan et al. portrayed CoV2 as a lab construct built by modifying a bat virus like ZC45 with a CoV1-like RBD swapped in. The CCP would have us believe that it evolved naturally from a bat virus like RaTG13. Although RaTG13 is also a lab construct, it presumably was built by modifying a bat virus with the RDRP from RaBtCoV/4991 swapped in. These all started out as bat viruses. Is it really correct to deny CoV2 is a bat virus just because it is also a lab product?
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PETER ROSS
4/17/2021 11:19:58 am
https://www.samueleckert.net/isolat-truth-fund/
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Fuddman
4/17/2021 12:01:12 pm
I failed German in college. Is there an English version to this site?
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Errata
4/17/2021 06:22:45 pm
@Fuddman: I browsed the website for you. It is a virus denier site with a rant along the lines we hear from Peter Ross. There is a page there that enumerates seven lines of reasoning which it coaches proponents on countering. Basically, all scientific evidence is indirect and they find one way or another to reject any proof that might be offered for the existence of the CoV2 virus.
David Rivard
4/20/2021 10:28:35 am
and hmmm, at least in this country there is, to date, 67,557 positive (in situ) PCR test verified C-19 cases, and we are the only country that does not lie. The global total confirmed today is 142,293,386. This means that, with all other countries lying, there is a 99.954 percent chance of C-19 being fake. Peter's analysis is brilliant.
PETER ROSS
4/17/2021 11:23:03 am
EMF-sensitive GMO Crops & Animals & Ozone
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Errata
4/17/2021 03:31:10 pm
If COVID-19 were caused by a bacteria, it would respond to antibiotics which it does not. Furthermore the pathogen would have been quickly found under a microscope.
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PETER ROSS
4/17/2021 08:55:43 pm
@Errata
Fuddman
4/18/2021 09:21:27 am
"Biological warfare, like all warfare, is based upon deception, including sophisticated disinformation campaigns..."
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Fuddman
4/18/2021 01:45:42 pm
Some quotes from the cited reference:
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Errata
4/18/2021 05:41:10 pm
CoV2 + deception = bioweapon
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Nerd has power
4/18/2021 06:31:08 pm
@Fuddman
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nonameneeded
4/18/2021 09:04:07 pm
Your point about the superantigen paper is well taken. It's computational and that's its weakness. This really invites a tour de force paper demonstrating that the putative superantigen acts as such in humanized mice (with hACE2 and hematopoietic cells). There are many clinical papers emerging showing associations between certain TRVBs and severe disease/MISC/hyperinflammation, although of course that is not proof that this is mediated through a nonspecific superantigenic effect.
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PETER ROSS
4/19/2021 12:13:10 am
@nerd
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PETER ROSS
4/19/2021 12:15:47 am
of my doubts is about the person to person transmission route - that seems more like a tradtional assumption lacking direct evidence; frankly it's suspicious that direct person-to-person experiemtns haven't been mentioned, considering that the entire planet has been on prison lockdowns for only that theoretical reason.
Bro
4/21/2021 05:58:42 pm
You can find the virus phylogeny tree here: https://nextstrain.org/ncov/global
nonameneeded
4/18/2021 09:53:06 pm
I think it is worth directing our attention to the vaccine debacle, namely the current J&J suspension. This vaccine was deemed to be the "promised one" because of it's one-shot and low cost features, stable for months in the refrigerator. While its suspension is ostensibly to ensure its hazards don't outweigh the benefits, I am frankly incredulous that Moderna's and Pfizer's mRNA vaccines have not in their own right precipitated platelet abnormalities. I have seen quite a number of reports of ITP after these vaccines, not to mention anaphylaxis.
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nonameneeded
4/18/2021 09:54:46 pm
Fauci's absence from the 2020 paper is most curious given his other colleagues being together with him on this same topic (and him first author!) in the 2014 paper. I suppose it would be too obvious how badly he was shilling for Moderna if he were on the most recent commentary.
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Fuddman
4/19/2021 09:27:22 pm
@nerd has power
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Errata
4/20/2021 08:13:55 am
What you missed is that when testimony is discredited, it is rendered meaningless not false and therefore the opposite is not established as true.
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Nerd has power
4/20/2021 08:59:29 pm
Thank you, Errata. Excellent point.
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Fuddman
4/22/2021 08:50:17 am
Per @nerd “ there are many papers that do not mention RaTG13 and yet prove that SARS-CoV-2 is a real virus. ”
evidence
4/22/2021 05:42:24 pm
@Fuddman [4/22/2021 08:50:17 am]
PETER ROSS
4/20/2021 03:07:25 am
Below an intial report based upon personal testimonials of individuals on the experience with the Pfizer syntheic RNA GMO injection adminstered intially in December 2020 to approximately ~6 million citizens in nearly all case in two separate doses.
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PETER ROSS
4/20/2021 03:08:59 am
...cont
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PETER ROSS
4/20/2021 03:10:08 am
cont...
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PETER ROSS
4/20/2021 03:13:37 am
...cont
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PETER ROSS
4/20/2021 03:14:15 am
...cont
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David Rivard
4/20/2021 10:36:10 am
OK, on this date our country has 67,557 positive (in situ) PCR test verified C-19 cases, and we are the only country that does not lie. The global total confirmed by Yale today is 142,293,386. This means that, with all other countries lying, there is a 99.954 percent chance of C-19 being fake.
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David Rivard
4/20/2021 11:24:46 am
@Nerd: Is HCQ available to your people? Answer; HCQ is available at any drug store, cheap, to most countries with Malaria. It is used as a prophylaxis and the U.S. State Dept. still recommends its use (for Malaria). The DOD still force feeds HCQ to its members, as they did to me for well over a year about half a century ago. Very sophisticated and educated people here are taking both Ivermectin and HCQ as a prophylaxis. I saw a need myself, with no testing, to go on the government Ivermectin/zinc/vitamin based treatment twice so far. Symptoms went away.
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Errata
4/20/2021 07:09:35 pm
https://www.covid19treatmentguidelines.nih.gov/antiviral-therapy/chloroquine-or-hydroxychloroquine-with-or-without-azithromycin/
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Jimmy Kudo
5/26/2021 09:16:13 am
You use HCQ just because it's an antiviral? Do you use aspirin for skin cuts as well?
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David Rivard
4/20/2021 11:47:04 am
More news from down under: Over the past 6 months or so, China is universally perceived as the new superpower. Gallup et al?? Why? Most folks believe that it successfully demanded that all countries should not believe their lyin' eyes.
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Errata
4/20/2021 11:55:57 am
There are some things you just cannot argue with.
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Fuddman
4/20/2021 08:41:53 pm
Continuing the discussion of Deception theory.
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Fuddman
4/20/2021 08:43:21 pm
https://ccpgloballockdownfraud.medium.com/the-chinese-communist-partys-global-lockdown-fraud-88e1a7286c2b
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Arnaud
4/21/2021 11:19:32 am
Google recently suppressed results for 4991 + vih. Before this week you were directed to
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David Rivard
4/21/2021 11:36:42 am
Good work fuddman! When I first suspected it came from a lab, my knee jerk reaction was "we can throw everything we have proven about immune responses out the window if it is synthetic." If war, they would not leave one potential advantage to chance. It would be logical that information from the CCP that is not withheld would mislead the trusted agencies to exacerbate the weapons effect. The trusted agencies would, in turn, be working on coverups. This would muck everything even further.
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Fuddman
4/21/2021 12:44:47 pm
@David Rivard
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Lois Gearhardt
4/21/2021 02:14:22 pm
Mmmm. I came down with the ccp virus (and I'm of the opinion it's also the Baric Fauci et al virus), last June. I'm 65, and I have never had any kind of flu or other virus so bizarrely vicious in my entire life. 21 days of utter hell. Every symptom in the clinical definition, what medicos would class as 'moderately severe.' No point going to the ER even if I could have stood to be carried. Three weeks of sequlae, had to use budesonide nebulizer 3-4 x a day for three weeks. I do not go for the mask crap,lckdowns, etc. And certainly not the murder shots. I wish there had been hcq or ivermectin available then.
nonameneeded
4/21/2021 11:41:52 am
When it comes to intentional vs accidental, doesn't the release from Wuhan seem a bit inconsistent with an intentional bioweapon? You would think they would launch it from Guangdong for plausibility, not Wuhan where the WIV is located and the foods eaten don't line up with the SARS vectors. The Wuhan epicenter to me is the greatest proof that the release was accidental. The alternative is that the release was coordinated by domestic or foreign (?who) actors who wanted to implicate/blame the Chinese regime and chose the Wuhan location carefully. In that case, the virus didn't even have to originate from the Wuhan lab....there are other labs where coronavirus research is being done...
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David Rivard
4/21/2021 12:32:26 pm
I guess that you would have to ask CCP about tactics, but it refuses to share any information that would make this "conspiracy theory" go away. Are their aggressive globally policies since the pandemic simply taking advantage of the situation or have they created a shortcut to global domination?
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Errata
4/25/2021 02:42:13 pm
Wuhan has the advantage that they can fall back on 'lab accident' if the 'natural spillover' doesn't sell. The current debate between these two interpretations shows the wisdom of that approach. If it had been released in Guangdong then the current debate would be instead between natural spillover and bioweapon attack.
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nonameneeded
4/25/2021 05:38:15 pm
That is an excellent point. In a strange way, the bioweapon and "natural jump from another species" theories have some points of convergence where the accidental lab leak doesn't, namely that we would expect to see *no explicit* signs of human manipulation in the nucleotide sequence even if the resultant spike protein does have something highly suggestive of manipulation, which is to say the furin cleaveage site (and I have not studied the other proteins much, it is possible there is a lot of stuff going on with the nonstructural proteins as well). We should thus see no added restriction enzyme sites, aggressive codon usage optimization, etc.
David Rivard
4/21/2021 12:19:12 pm
Also, the first thing that jumped out at me is "PCR protocol thus has every indications of being fraudulent" (rely on in silico sequences and other information from several CCP controlled labs) as it relates to testing for the early vaccine development push we enjoy today.
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Bro
4/21/2021 06:04:04 pm
The virus phylo tree is here for those who interested:
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Fuddman
4/22/2021 10:35:55 am
From your reference:
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Errata
4/22/2021 07:33:51 pm
@Fuddman: The phrase "...wholly dependent..." is a misrepresentation. The claim that PCR testing is false because it checks for the nucleocapsid protein sequence given by Shi is worse than misleading. The CoV2 sequence has been confirmed by many reliable sources so its sequence sectors used by PCR testing are well established. To claim PCR testing technology itself is a hoax is to dismiss the whole field of genetic engineering and the advances in biotech that have be made since Watson and Crick. But you must know this. Why do you post such things?
Errata
4/23/2021 07:08:41 pm
Nerd has power (4/18/2021): "I also don’t know whether this is an ethnic-specific design,... However, I want to point out that MANY people died in Wuhan, unlike what the CCP had reported. The situation was magnitudes-worse, and many people collapsed suddenly on the streets of Wuhan. So, in that sense, even if it was a design to target non-Asian ethnic groups, it was not a successful one. Maybe we will see that design in the next pandemic, if the CCP gets away this time."
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Arnaud
4/24/2021 12:31:46 am
Mortality rate 0,5% concerns infected people and not the whole population.
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Errata
4/24/2021 06:43:27 pm
Correct. Sorry if my phrasing was misleading. The potential existed for casualties up to that number. That is not to say so many actually died. I was just trying to show that it was plausible that reports of high casualties did not necessarily preclude some intrinsic resistance even when it was as high as 50%. A recessive allele giving resistance and having a frequency of over 70% would confer such a level of protection. Half a mass casualty event is still a mass casualty event. That was the point.
Errata
4/23/2021 07:10:49 pm
Some details about CCP vaccines:
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Fuddman
4/23/2021 09:48:48 pm
Discussion on deception, cont.
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Errata
4/24/2021 07:25:20 pm
@Fuddman:
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evidence
4/25/2021 04:32:15 am
Re: False notion about the supposingly high-threshold nature of bio warfare R&D in civilian research lab settings context (Option 2)
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evidence
4/25/2021 04:40:36 am
On the other hand, today, all (secretively performed) nuclear explosion events/tests can be quite easily monitored by the global surveillance instruments. You hardly can hide that anymore.
alejandro ipiña
4/24/2021 08:14:51 am
@Fuddman:
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PETER ROSS
4/24/2021 12:27:46 pm
CDC didn't have PCR test until end of February; what sequence, primers, probes, were they relying upon?:
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PETER ROSS
4/24/2021 12:20:00 pm
Why publish so late in the game - June 2020?
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PETER ROSS
4/24/2021 01:25:23 pm
Yes, everyone is focused on the elusive virus of a genome that's never been observed intact but rather constructed in silico based upon the RNA fragments slectively fished out from the monkey cell extract - contaminated with human and bovine RNA and DNA fragments - accoding to a pre-determined assumption that the virus is a SARS type.
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PETER ROSS
4/24/2021 01:35:51 pm
:Genetically modified probiotics should be banned"
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PETER ROSS
4/24/2021 01:52:38 pm
FEASIBILITY OF PROBIOTIC LACTOBACILLUS AND
bro
4/25/2021 09:29:58 pm
@nerd
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Errata
4/27/2021 05:43:44 pm
@bro
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Babstar
5/1/2021 07:12:20 pm
Paper: On the Origin of SARS-CoV-2: Did Cell Culture Experiments Lead to Increased Virulence of the Progenitor Virus for Humans?
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Nerd has power
5/2/2021 11:58:40 am
@Fuddman @Peter Ross
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Fuddman
5/2/2021 05:28:19 pm
"Please stop claiming on this forum that SARS-CoV-2 is not a real virus..."
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Nerd has power
5/2/2021 08:11:20 pm
It is the stance that opinions that do not agree with facts and logic are not welcome on this forum. This blog/forum is nothing but honest discussions on SARS-CoV-2, which are based on facts and logic. This has always been the theme.
Nerd has power
5/2/2021 12:12:08 pm
Errata made a great point (Errata 4/25/2021 02:42:13 pm) – “lab accident” is indeed the fallback plan of the CCP. So be careful the next time you are being presented with the “miner theory” or stories that solely focused on the bat lady Zhengli Shi.
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David Rivard
5/3/2021 12:10:25 pm
I guess it’s my job to bring this up now and then. Our citizens are far removed from the concept of a “World War”. Failing to understand this from a personal standpoint would be a natural conservative reaction, but failing to understand and act is unforgivable from a historic standpoint and this is where we entrust the job of threat mitigation and long term vision to our societal managers.
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Xoco Latte
5/3/2021 01:40:39 pm
What Nred wrote about these "new coronavirus" drills in Wuhan in September 2019 eerily reminiscent to the situation on the very day of 9/11. At elast half a dozen military exercises were held with some of them simulating exactly the things unfolding in reality...
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PETER ROSS
5/3/2021 06:10:28 pm
CCP is in league with The Globalists, who also held many 'pandemic' drills, incl. for a coronavirus outbreak at the same time.
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Xoco Latte
5/4/2021 12:39:45 am
I can remember some individuals looking to complete lunatics (at best) with similarly constructed pathological ideas who years later turned out to be just hired proxies of the perpetrators.
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Xoco Latte
5/4/2021 12:42:44 am
"I can remember some individuals looking to complete lunatics (at best) with similarly constructed pathological ideas who years later turned out to be just hired proxies of the perpetrators."
PETER ROSS
5/4/2021 03:51:17 am
Not sure to whom you're addressing as "troll" or "proxy of perpetrators".
PETER ROSS
5/4/2021 04:17:26 am
https://leohohmann.com/2021/04/30/highly-cited-covid-doctor-comes-to-stunning-conclusion-govt-scrubbing-unprecedented-numbers-of-injection-related-deaths/?fbclid=IwAR2XbBL97DqyH4ENHDNEZjB4mNi_nI4FzPD_88JWqU8Pe4gU0A3GmXJkqz0
PETER ROSS
5/4/2021 06:58:19 am
"The BAC [Bacterial Artificial Chromosome] approach, originally applied to the transmissible gastroenteritis coronavirus (TGEV) [5], has been successfully used to engineer the infectious clones of the feline infectious peritonitis virus (FIPV) [13] and the human CoVs (HCoVs): HCoV-OC43 [14], SARS-CoV [15], and MERS-CoV [16], and it is potentially applicable to the cloning of other CoV cDNAs, other viral genomes, and large-size RNAs of biological relevance."
David Rivard
5/4/2021 09:34:07 am
Peter, I think your point below deserves more attention:
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PETER ROSS
5/4/2021 11:02:54 am
The bacterium-virus combo can explain why the virus is so elusive, and potentially adds a lot of stability. Bacteria can also be weaponized in addition to carrying a deadly virus payload and can be coated with stuff that adds stability. Under the light microscope it will look like an innocent commensal that's "contaminating" the biological specimen being analyzed for viruses.
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David Rivard
5/4/2021 11:44:49 am
Peter, I must say I like your bacterium-virus combo theory. It really should be explored. With the right variants it could even be more easily contained to a geographical context. Interesting delivery system.
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Fuddman
5/4/2021 01:28:19 pm
@nerd
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John Kelleher
5/4/2021 02:49:54 pm
Comments of derision based on one's political party affiliation does nothing but dilute the objectivity of this blog.
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Errata
5/4/2021 04:13:46 pm
On the topic of premeditation, I think this from Dr. Steven Quay deserves more attention:
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Errata
5/4/2021 06:24:18 pm
@David Rivard and Peter Ross
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PETER ROSS
5/4/2021 10:27:25 pm
@Errata
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Errata
5/5/2021 09:26:12 am
@Peter Ross
David Rivard
5/4/2021 10:40:31 pm
@errata, yes I agree with your assessment. C-19 mimics many other diseases and the testing certainly is deficient at many levels. Pragmatics push many countries and I related that mention to another matter. There is clearly no leadership, even at regional levels. Presidents and their agencies have been on their own and even scientific experts, like yourself, are sifting through data with small like minded groups. Much of the raw data is either not trusted because standards cannot be adhered to, or when they are, organizations generating or publicizing it are at least political suspects. Scant shared or trusted data means no comprehensive intelligence production. Incompleted intelligence means no credible public policies.
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John Kelleher
5/5/2021 12:47:30 pm
Peter Ross said " That this "plague" is 0.25% actual mortality and 99.75% a centralized, military-grade, mass media-driven psychological operation directed towards mandating RNA and DNA injections as the only option is kinda scary-weird.
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PETER ROSS
5/5/2021 02:19:45 pm
@John Kelleher
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PETER ROSS
5/5/2021 02:46:27 pm
https://breaking-news.ca/the-new-nuremberg-trials-2021-please-share-this-info/?fbclid=IwAR2k--XU_ek8ik8UnuEfgshmub0bkZ2JJSjfIGRB_SWXDiql70te7In2nZ0
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PETER ROSS
5/5/2021 12:54:35 pm
@Errata
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John Kelleher
5/5/2021 03:27:10 pm
Peter, I do not disagree with most of what you are saying , though this blog is not the place for political opinions.
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John Kelleher
5/5/2021 03:31:09 pm
He stated the Covid-19 virus was made in the lab. Does anyone here have those credentials ?
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PETER ROSS
5/5/2021 06:01:51 pm
I'm convinced ot the lab original since first reading @nerd's blog and since then have followed both the molecular bio analysis from various sources and the strong circumstantial evidence - for example guys like Fauci and Echohealth Alliance (Rockefeller>Kissinger) and some NATO and Ft Dietrich folks all have associations with these crimes.
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Errata
5/5/2021 06:14:20 pm
Peter, you should listen to John. His point is quite correct. You are making a fool of yourself by posting drivel. Quit the job of trolling this site. Whoever is paying is not paying you enough. If you keep this up you will get into the bad habit of sounding like a fool. Bad habits are hard to break.
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Errata
5/5/2021 07:00:28 pm
@Peter Ross
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Errata
5/6/2021 03:46:24 pm
@Peter
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PETER ROSS
5/6/2021 04:22:07 pm
1) Describes VERO-cell-SARS, in toehr words green-monkey-SARS, not human-SARS nor human-SARS-CoV--2
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PETER ROSS
5/6/2021 04:49:02 pm
cross-reactivity proves nothing. It's just cross-reactivity.
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John Kelleher
5/6/2021 06:19:09 pm
Peter Ross wrote," At least show that for the Rhesus apes - and using ape virus - not xenogeneic green monkey cell junk extract...".
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Nerd has power
5/9/2021 07:08:38 am
@Peter Ross
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'bro
5/9/2021 12:42:16 pm
@nerd do you think this virus can be transmitted in fecal oral rout perhaps by water contamination? I saw a few papers . I am not sure if these are correct. Please see this
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Nerd has power
5/10/2021 05:00:52 pm
I do not know. I have not been paying attention to such literature. However, my memory seems to say that no infectious viruses are present in feces, although one may be able to detect RNA sequences there. I think the paper you are citing here is more or less supportive of this scenario.
Errata
5/10/2021 05:55:41 pm
@'bro
PETER ROSS
5/22/2021 10:05:48 pm
@nerd
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Bro
5/10/2021 06:48:29 pm
Thank you @nerd and @errata,
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john Kelleher
5/10/2021 08:53:27 pm
nerd has power thanks for your work.
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nonameneeded
5/11/2021 08:09:50 am
Can we discuss the origin in a more systematic way?
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nonameneeded
5/11/2021 08:11:03 am
Having seen in recent months China's poor SARS-CoV-2 vaccine efficacy, the glass bridge incident, and the Chinese uncontrolled rocket fiasco:
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Xoco Latte
5/12/2021 01:40:34 am
nonameneeded, it has been a refreshing impulse reading your ideas.
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Thatguy
6/11/2021 11:16:32 am
As far as who had discussed such work beforehand. Most likely Baric in NC. Fauci made sure to add Wohan lab or China to the end each time he answers that question.
John Kelleher
5/11/2021 09:20:03 pm
nonameneeded , thanks for your research. An interesting fact is that the Fauci's and the Cuomo's have been friends for 40 years. Gov. Andrew's father ,Gov. Mario would have Anthony come by as they are NYC boys.
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nonameneeded
5/12/2021 06:30:15 am
You make an excellent point and I have no doubt that China has been weaponizing the coronaviruses in their bank. I think the obsession with the money (a paltry 3-7 million dollars) Fauci funneled through Eco Health Alliance is smoke and mirrors. Anyone in science knows this is chump change, and that Shi Zhengli was not strapped for cash since she could always go to the Chinese military for something this important and would get whatever money and manpower she needed. Rather than perseverating on US taxpayers unknowingly funding GOF research it's much more important to investigate how much exchange of information was there. Were virus stocks transferred between countries? Were modifications and innovations developed in the US (at places like UNC Chapel Hill with Ralph Baric or Vineet Menachery down in UT Medical Branch, etc.) tested in nonhuman primates in China? What exactly was the US/Fauci getting out of giving that money? It was either trying to get a closer look into the goings on at WIV, and/or to get new viral backbones that Shi Zhengli found on her speleologic expeditions, or it was to execute or complete certain experiments that were conceived or partially executed in the US in the WIV shadow lab. I do not for a second believe that Shi Zhengli's mentor Ralph Baric or his other acolytes in the US did not continue their GOF efforts and closed up shop hoping that cash Fauci was sending to China would some day bear fruit.
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nonameneeded
5/12/2021 06:31:31 am
Anyone who knows Fauci (and I have met him, although I can't claim to know him to any great degree) knows that he has a Napoleon complex and is dying inside over not having won the Nobel Prize for HIV-AIDS (I'm not sure why he would be awarded that, since lack of containment in that pandemic also lead to mass death and Fauci's vaccine never materialized - it was the anti-retrovirals that he had nothing to do with that saved lives). Perhaps COVID provided him a launching pad to apotheosis and prizewinning? The timing coinciding with the research done by Fauci's subordinates on generalizable coronavirus vaccines launched by an mRNA platform in the years preceding, and also the remdesivir work the year prior, is all too inplausible.
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nonameneeded
5/12/2021 07:13:57 am
Fascinating new study on innate immune entrainment of the Pfizer vaccine:
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Annette
6/2/2021 05:04:40 am
Interesting the CDC is now priming us up for fungus vaccines, yet it looks as if they are creating a nice little money generating business in vaccines for the side effects of the vaccines! https://www.rnz.co.nz/national/programmes/sunday/audio/2018797557/why-the-next-pandemic-could-be-a-potentially-deadly-fungus
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Fuddman
5/12/2021 09:37:23 pm
The RT-PCR test is useless and has been since the beginning. That according to 22 scientist who issued this report a few months ago.
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Errata
5/13/2021 04:50:20 pm
@Fuddman
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Xoco Latte
5/13/2021 04:29:23 am
A new paper from mostly Chinese authors showing quite a number of evidential results for the functional importance of the furin cleavage site PRRA in the spike of SARS2.
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nonameneeded
5/13/2021 05:55:20 am
I speculated at the start of the pandemic that the multinucleated syncytia could be a key feature of the virus. These have also been observed in HIV, where HIV-infected T cells blend together with macrophages and generate viral reservoirs. Whenever you have a large blob full of virus, and have the capacity to form syncytia, you now have nonvirionic lateral spread (cell-to-cell without virus every budding off into the interstitial space) and also a nearly endless source of virus that may not be as susceptible to apoptosis as normally infected cells. T cells may surveil the surface but may lack the capacity to decommission these virus-packed blobs. And lateral spread will escape antibodies obviously.
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nonameneeded
5/13/2021 06:16:30 am
Some interesting papers:
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nonameneeded
5/13/2021 06:24:18 am
https://www.sciencedirect.com/science/article/pii/S0969212620303725
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Errata
5/13/2021 04:22:44 pm
They clearly had the ability to create such a virus, so similar as it is to other work by Zhengli Shi. They also had the ability to create vaccines of some sort. Their belief in traditional vaccine technology does not preclude their creation of this virus and a vaccine against it nor does it render improbable that they released it maliciously. Your argument is that they could not have done it because there is a better way to do it and they did it wrong. Sorry if I snicker but that is just silly.
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nonameneeded
5/13/2021 04:53:32 pm
I think you underestimate the sophistication that went into creating this virus. It is not the technical skill of serial passaging or inserting the FCS. It is the fine tuning of the in vivo response which must have been done in viverrids or nonhuman primates (or, God forbid, prisoners - a thought that occurred to me at the start of the pandemic) that is difficult. You have to create something much less immediately lethal than SARS-1 or MERS but also far more contagious and with a prolonged incubation period to facilitate spread.
nonameneeded
5/13/2021 06:38:59 am
Two more interesting papers:
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John Kelleher
5/13/2021 11:39:20 am
Dr. Kory of the FLCCC's recent vid showing the continued disinformation by the WHO and Big Pharma mainly on Ivermectin .Irregardless of your view on Ivermectiin this is still a thorough presentation on the extent to which the WHO will not advocate for our health.
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Errata
5/13/2021 04:06:46 pm
@nonameneeded
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Errata
5/13/2021 04:09:00 pm
"I am not convinced that Chinese science is at the point of sophistication to have generated the virus."
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nonameneeded
5/13/2021 06:17:53 pm
Errata:
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nonameneeded
5/13/2021 06:18:46 pm
“The incidents you cite do show a certain reckless disregard for margins of safety but they do not discredit the basic ability to create such things. In any case the technologies of bridge construction and rocketry differ substantially from wet lab work. They depend on calculations of strength under dynamic loads and mistakes are about margins of error whereas the big hurdles for virus research are cleanliness and purity while mistakes are about contamination. These are quite different challenges. We do not say things like "the shed that man built is rickety, no wonder his socks are dirty.””
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nonameneeded
5/13/2021 06:19:45 pm
It’s not just an interesting theory. I saw what Fauci was doing at NIH in January-April, and it was shocking. His behavior was inconsistent with normal behavior of a public health authority. It was just as suspect as the behavior of the CCP. In fact, equally so, which is why I find the bioweapon argument strong but am unable to figure out who was the prime mover - the CCP, or their collaborateurs in the US. Fauci’s team had fine tuned their generalizable coronavirus vaccine platform in 2016-2019, remdesivir had promising results at Rocky Mount Labs (part of NIH) for MERS in nonhuman primates in 2019, and Fauci in January stated to his lab leaders that NIH was likely to play a major role in COVID. Fauci sent an NIH delegation to China in January 2020 while the CDC was barred; he ordered the creation of the COVID vaccine on January 11, 2020 (his words), but told Trump to keep the border open with China, he deceived Americans as to the danger of the virus, lied about masks (Americans and his own NIH employees were told not to wear them for months), lied about the virus being airborne (Americans and his own NIH employees were told it was not a major mechanism of transmission), manipulated the remdesivir “adaptive” clinical trial endpoints (removed mortality/intubation/hospitalization as the composite primary endpoint and switched to days to hospital discharge), etc. His hands are dripping with blood.
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Xoco Latte
5/16/2021 01:40:12 am
Very interesting line of thoughts. Without hard evidence this problem might just stay an unsolvable mystery with wildly opposing theories with obfuscating layers of dis- and/or misinformation channelled by the culprits and its opponents. China was not fully prepared to this event even though almost certainly was in preparation of something similar. Once attacked and not being able to contain the epidemic, decided to reverse the attack and propagate the epidemic to abroad. The very strict lockdown measures and a mediocre-quality vaccine helped to contain the epidemic at home, unlike for most of other countries, especially the US. Biowarfare strategical experts would know better, especially when they would be better knowing the behind-the-scene information.
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evidence
5/14/2021 09:19:53 am
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evidence
5/14/2021 09:25:16 am
The bold UK epidemiologists looked only at the DATA of the vaccine trials - and at the same time ignored the vaccine companies' RECOMMENDATIONS. That was not only extremely bold, but also very smart, since you cannot exclude a bias in those companies' recommendations, because: (a) once the population has found out that only one shot would work and might be even preferable - this possibly slashes the revenue by 50%. Which company would be happy to recommend that (uncertain) solution first hand? [NB: Eventually, the efficacy data of the trials themselves had even to be revised for the better regarding a single shot (see Bernal et al, cf. below), because the companies did not exclude the first two weeks after the first shot for their trial analysis (!) ]
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evidence
5/14/2021 09:37:10 am
- but this only if we do not appreciate the exponential nature ('butterfly effect') of the first phase of every pandemic storm - including a 3rd wave. Mid Feb 2021 was exactly the time, when the 3rd wave had not yet fully materialized for Germany; one could only predict the coming with certainty, according to the grim replication rate number R>1 at that time.
evidence
5/14/2021 09:40:45 am
(**) This point of risk assessment (including Covid) is discussed for example in this essay
Jimmy Kudo
5/15/2021 07:45:18 am
You might be right.
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Nerd has power
5/16/2021 12:08:16 pm
Excellent exchanges in the past few days. I enjoyed reading your analyses @nonameneeded @Errata @evidence.
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Nerd has power
5/16/2021 12:14:54 pm
I also would like to comment on whether the CCP aimed for a precise fatality rate or transmission rate when creating the bioweapon. I would say not necessarily.
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The CCP is NAZI
5/16/2021 12:48:03 pm
Thanks, Nerd has power. I am not in the same field as you are in, but I have more trust in you than those who developed the vaccines even though I don't know much about you. I know my reply here is not so relevant to what you said, but I am very skeptical about the vaccines. Do the vaccines in general really work? I doubt it, as HIV has been around for decades, yet there is still no vaccine for it. Why would I believe CCP virus vaccine would work if it also has HIV insertion? My friend is a biologist and had the vaccine and told me that she is fine. I would say that it's too early to say if she is really fine or not. I heard that these vaccines have population control and chips for ioT(Internet of things) and cloud. I'm not sure if this is a conspiracy, but is this really possible? Why would we trust the vaccine more than HCQ? Would you take the vaccine or not? Thank you!
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Nerd has power
5/22/2021 09:44:00 am
Sorry for the late reply. I am not an expert on vaccines myself. I can only describe my personal choice here.
nonameneeded
5/16/2021 02:54:10 pm
Nerd has power:
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Errata
5/16/2021 05:37:41 pm
@nonameneeded
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nonameneeded
5/16/2021 03:12:48 pm
“Of course Fauci’s hands are dripping blood; I would make the same comment. However, my reasons would be based more on his denial and smear of HCQ. To me, the reason Fauci and his-likes defame HCQ is because they knew HCQ works in protecting infected people from sever disease and death. HCQ is moderately effective in the prevention of infection too. Wouldn’t that knowledge (that his personal health is guaranteed by HCQ) add to his comforting looks at the beginning of the pandemic? I think it’s possible.”
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Errata
5/16/2021 06:04:58 pm
@nonameneeded
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Xoco Latte
5/17/2021 04:33:07 am
I concur that this intelligent exchange of ideas seem to steer back this comment section to its original path albeit with more focused attention on the "who did it" part, once the "why is this virus a lab-made one" is more or less now a meanstreamly supported idea.
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Annette
5/29/2021 04:19:39 am
Main stream news at last. We have been touted for being conspiracy theorists in Aotearoa. (https://www.nzherald.co.nz/world/covid-19-coronavirus-why-the-wuhan-lab-escape-theory-dead-and-buried-months-ago-has-risen-again/ZGTEKJJEN7MZ3Z4Q27IWXQZK3Q/)
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Fuddman
5/18/2021 04:46:18 pm
“Importantly, the backbone of the bioweapon, ZC45/ZXC21, were discovered by a Chinese PLA research lab.”
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nonameneeded
5/18/2021 07:00:13 pm
I agree that there are holes in the theory when sequences are posted directly to a public database of what are supposed to be the backbones for future killer viruses.
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Errata
5/19/2021 03:24:43 pm
@Fuddman: "Yeh, makes all kinds of sense for the chicom PLA to keep their weapons secret that way"
nonameneeded
5/20/2021 09:54:08 am
Errata:
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Errata
5/20/2021 02:49:56 pm
@nonameneeded: "I have some doubts that Shi Zhengli had the capacity to fine tune a bioweapon that would have so much asymptomatic spread and prolonged incubation...Where I lack the faith you have (in the CCP scientists) is in polishing off a backbone that is simultaneously clandestine and not innocuous, subclinical in many and deadly in some."
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Nerd has power
5/22/2021 09:55:00 am
Again, very interesting exchanges @nonameneeded @Errata.
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PETER ROSS
5/22/2021 11:01:58 am
One of you guys wrote this up?
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PETER ROSS
5/22/2021 10:19:04 pm
Re: Published analysis for composition of synthetic RNA injections:
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nonameneeded
5/23/2021 06:14:44 am
Regarding the vaccines question, setting aside the platforms, I strongly recommend it for the elderly and even people >50 years old. My recommendation is more tepid in the 30-50 age groups. I think it's a travesty that this is being pushed on young people in their 20s, adolescents, and children.
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nonameneeded
5/23/2021 06:16:22 am
The mRNA candidates in my view give excellent antibody responses and apparently CD4 T cell responses. Moderna tailored their lipids based on prior research and thus arrived at something that generates good responses in the CD4 T cell compartment. However, their early data doesn't show good CD8 T cells. Pfizer/BioNTech apparently launched 2 separate candidates and chose after phase 1 the candidate that gave better CD8 T cells. Their lipids were tailored based on prior research on cancer vaccines (I believe prostate cancer vaccines), which were designed to force strong CD8 T cell responses. From an immunologic perspective, I think the Pfizer vaccine is probably the best. There are concerns here, however, namely safety concerns. First, with induction of spike protein expression at high levels from cells there is the risk of epitope spreading, where the attack on muscle-cell expressed spike protein triggers additional T cells and B cells to come in and start attacking natural muscle proteins. That could be what's underlying the myocarditis (skeletal and cardiac muscle having some cross reactivity). Alternatively, the lipids themselves could skew the immune response towards autoimmunity and perhaps stronger fungal immunity and weaker viral immunity. There is a paper to this effect (below). Finally, we don't have good data on exactly where these nanoparticles distribute. With adenoviral vectors, we have a good idea of what cells they infect (many) and what a broken adenovirus can do. I have not heard of a lot of molecular mimicry or epitope spread from conventional adenoviral infections, and I don't know if that is related to differential MHC expression, how the costimulatory molecules are expressed, etc. With the lipid nanoparticle, we are not dealing with a known ancient pathogen vector, to which our immune system is adapted and more importantly has insulted itself from developing overt autoimmunity. We literally have no idea what multiple doses of the lipid nanoparticles will do long term. Provoke connective tissue disease? Lupus in several years? We simply don't know. I am not against new platforms, I am against them being pushed on people coercively or on populations who are not at high risk from the disease, such as young healthy people.
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PETER ROSS
5/25/2021 05:58:08 am
There is no evidence these synthetic RNA injections (they're not "vaccines") have anything going for them but horrific side effects.
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Fuddman
5/23/2021 02:02:31 pm
@Ross
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PETER ROSS
5/25/2021 06:06:52 am
yeah, very fishy.
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nonameneeded
5/26/2021 07:15:33 am
Apparently EcoHealth alliance got $40 million from the DoD/Pentagon:
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Errata
5/26/2021 11:49:19 am
@nonameneeded:
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nonameneeded
5/26/2021 04:31:33 pm
Yes, that could explain it, and also why the mRNA shots may have less of this complication. Since they're mRNA, there's not alternative splicing. Any coagulation induced by leached off spike protein would have to be due to cell death, shear forces, etc.
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David Rivard
5/26/2021 12:34:13 pm
In popular media today the Biden Administration to "call a full investigation on origin", being pressured by many prominent countries. Having not resurrected Mike Pompeo's distillation on the DOS website (in fact, hiding it in the archives). As only the U.S. can take the lead of such initiative, all other countries must remain pragmatic. I worry about countries not conforming to China's Belt and Road initiative, and particularly those standing in the way of the South China seas expansion, experiencing their "4th wave" as Japan currently is.
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Errata
5/26/2021 04:24:40 pm
@David
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alex
5/27/2021 09:25:34 am
@Errata
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Errata
5/30/2021 11:39:57 am
How did they do it?
nonameneeded
5/27/2021 07:08:15 pm
If this was a bioweapon released by China....one geopolitical question I have is why Russia is building a friendly alliance with China?
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Errata
5/30/2021 12:18:19 pm
Biden is hostile toward Putin so he would only side with the USA against China if he believed the USA was going to confront and defeat the CCP. He apparently does not believe that. If the USA does not do that then China has won WW3 and can be expected to exploit its momentum aggressively. Putin's choice is to risk China doing so in his direction by allying himself with the West or to ally himself with China and protect his flank perhaps joining in the spoils. Realistically Biden cannot lead the USA to war with Chinese because they put him in power with help from the coalition of liberals and vested corporate interests. The Left wants to be communist, not defeat communism, and it is funded by those milking the Free Trade cash cow. The military is right leaning and Biden's status as the Chinese POTUS is too demoralizing for a coordinated focused effort against the Chinese by the military under his leadership. They would doubt his sincerity and balk at the risk of being hung out to dry after committing themselves too deeply. My read is that Putin looks at things this way, he has picked his winner, and placed his bet on the Chinese.
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Jimmy Kudo
5/31/2021 12:56:24 am
"Realistically Biden cannot lead the USA to war with Chinese because they put him in power with help from the coalition of liberals and vested corporate interests. The Left wants to be communist, not defeat communism"
David Rivard
5/28/2021 04:35:19 pm
Remember the word "classified" information in all of these news releases. Congress will soon authorize intelligence release (s). I wonder how much of this cooperation is damage control by an administration that obviously benefited, and exists because of the pandemic. Can thy be trusted for an honest evaluation?
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evidence
5/29/2021 05:30:19 am
Re: (1) Accident scenario cannot be discarded by the fact that bogus Pangolin sequences had already been prepared/submitted as early as Sep 2019: tMRCA not to be conflated with index case infection;
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evidence
5/29/2021 05:35:06 am
[..] while in contrast the (later/subsequent) tMRCA is the time point, when at least TWO lineages do not die out anymore (schematically depicted for example on Fig. 2 [p.9 pdf] in the above paper:
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evidence
5/29/2021 05:49:03 am
[3]
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evidence
5/29/2021 05:52:01 am
[part 4]
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evidence
5/29/2021 05:55:19 am
At EcoHealth. At funding agencies (USAID, DTRA, DARPA, DHS, and NIH). At publishers (Springer-Nature and Lancet).
PETER ROSS
5/30/2021 05:13:28 am
Somebody posted that EchoAlliance (Rockefeller, WWF origins) has an annual budget of $90 million.
Xoco Latte
5/30/2021 01:25:29 am
Uh, dear evidence, that was a very longish essay to comment on. A very thought-provoking one, and that's quite an understatement.
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Xoco Latte
5/30/2021 01:45:45 am
So the slow populational uptake of the infection is IMHO a circumstantial evidence for accidental release only involving a single patient zero, especially if, even with some lag (2-3 days the most), all secret efforts have been made to control her personal contacts, and this eventually failed to stop the chain of infections but substantially held R0 far below 1.0.
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Xoco Latte
5/30/2021 01:53:47 am
Correction of the above:
PETER ROSS
5/30/2021 03:47:41 am
{hasn't slipped my mind that I owe @nerd some homework, but meanwhile just some related geopolitic}
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PETER ROSS
5/30/2021 05:20:54 am
Re: Attempted Analysis of Pfizer/Moderna Preparations:
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Nerd has power
5/30/2021 07:21:07 am
@nonameneeded
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Nerd has power
5/30/2021 07:25:58 am
Finally, I would like to share my thoughts on the suggestion that the pandemic could be due to an accidental leak of a virus intended for VACCINE development. In my opinion, this is just not plausible. There are several ways to argue against this. I will try two here.
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nonameneeded
5/30/2021 11:48:56 am
Very insightful. I agree. There are clear attempts at concealment up to the point of the bare essentials of pathogenesis. They worked hard to put in pathogenic features but equally hard to cloak them. Bioweapon 100%.
Errata
5/30/2021 06:52:19 pm
@Nerd
Errata
6/1/2021 07:05:43 pm
@Nerd
Errata
5/30/2021 06:56:53 pm
@evidence
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Jimmy Kudo
5/31/2021 12:44:39 am
What? "Hospital was erected so quickly" because of the mass infections and the current hospitals were full, with more people's lives at stake.
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Errata
6/2/2021 02:23:58 pm
Jimmy Kudo, the motive to erect the hospital quickly was clearly there for the reasons you state. However motive does not guarantee the means. The speed at which it was done was remarkable. There was clearly a plan worked out in advance including the construction and stockpiling of prefab units.
Fuddman
5/31/2021 01:25:35 pm
If Nerd facts & logic say RATG13 is fake, then, by the same facts & logic, ZC45 and ZXC21 are also fake.
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Errata
6/2/2021 04:49:59 pm
As Yan conceded, ZC45 may not be the exact backbone but whatever really was would be similar. That concession implies recognition that ZC45 might possibly be fabricated as well. But what would be the point? In any case the issues over the synonymous/non-synonymous mutations and the matching E proteins would remain. One might wonder why ZC45 and ZXC21 were ever published. To my mind it only caused them trouble. I've toyed with the idea that it was a SNAFU. It seems more likely to me that they are real viruses mistakenly made public than that they are fabricated viruses published for some obtuse purpose. I could change my mind if someone presents a theory that makes sense. Do you Fuddman have one?
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nonameneeded
6/2/2021 10:46:17 pm
Well, unless they were real viruses published in good faith and someone else was running the bioweapons program...
Fuddman
5/31/2021 02:20:42 pm
There were two inventors of the sequence for something called sars cov 2. They were Shi Zhengli and Yong-Zhen Zhang.
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Bro
6/1/2021 08:53:26 pm
Apparently the spike protein by itself can bind to ace2 receptor of vessels and damage cells. So either vaccine that make millions of this protein or the virus potentially damage vessels! Why this is not discussed!!!
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Errata
6/2/2021 04:30:25 pm
It is obvious that a vaccine may do some damage by emulating the pathogen. It is worthwhile to study and interesting to read the results of such studies. The approval of a new vaccine wraps all harmful effects up together in the safety and efficacy trials. In the end the decision to administer or receive a vaccine is made by weighing the risks against the benefits. In the case of damage done by CoV2 spike proteins circulated by a vaccine, that damage would be done to a greater degree by contracting CoV2 itself. It is not that the vaccine is harmless, it is that CoV2 is more harmful and the risk of getting CoV2 great enough that the risk of the vaccine is the lesser danger.
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evidence
6/2/2021 04:29:10 am
Re: Post by Xoco [ Xoco Latte 5/30/2021 01:25:29 am] in reply to my earlier post about Liu pangolin paper timing [evidence 5/29/2021 05:30:19 am] : Time of patient zero infection estimate (tIC) impossible to infer from tMRCA estimates + post-tMRCA molbio data alone (i.e.,without further circumstantial evidence)
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evidence
6/2/2021 04:38:44 am
Hence, no best guess possible from molbio data and statistical analyses alone for inferring tIC from either or both, tMRCA estimates and post-tMRCA pandemics behavior, and subsequently not possible to decide accidental vs intentional release at least from that knowledge alone.
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evidence
6/2/2021 05:20:43 am
Re: Post by Errata [Errata 5/30/2021 06:56:53 pm] in reply to my earlier post about Liu pangolin paper timing (not refuting accident scenario) [evidence 5/29/2021 05:30:19 am]
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evidence
6/2/2021 05:36:39 am
..., my concern about the Pekar paper extimates would remain unchanged, even if it happens to be, that [direct, e.g., intelligence/whistleblower] evidence eventually would show us, that the IC-tMRCA time difference in fact has been exactly 35 days (as their estimate would predict). However, the proposed absolute dates they are giving [tIC Nov 4 2019, tMRCA Dec 9 2019] are next to impossible in my mind.)
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PETER ROSS
6/2/2021 11:48:22 am
"Communist China at the VERY LEAST is guilty of covering up the spread of the Wuhan virus. The coverup continues putting every single living being at risk of the next great pandemic."
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nonameneeded
6/2/2021 10:44:39 pm
Francis Collins, chief liar:
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David Rivard
6/3/2021 12:04:12 pm
OK, thanks in no small part to this site's efforts, we are now in the "Accidental vs. Intentional Release" phase of the research.
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WesternPeak
6/3/2021 01:03:13 pm
The following is from an interview of Vineet Menachery at the 2019 Microbiology Society’s Annual Conference in Belfast:
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David Rivard
6/3/2021 02:10:18 pm
Of course, there is the general media and major scientific publications that definitely did follow widely accepted scientific methods. Along with the current administration's acquiescence to China's aggressions abroad, in addition to not pressuring the CCP for information that would definitely impact therapies. Could it be CCP DNC collusion? They both got what they wanted.
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Nerd has power
6/5/2021 08:39:44 am
@Errata
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Fuddman
6/5/2021 01:46:34 pm
@nerd
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Nerd has power
6/5/2021 03:21:29 pm
Not the paper you listed @Fuddman. It's this one:
Errata
6/9/2021 02:35:46 pm
@Nerd
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Errata
6/9/2021 02:47:39 pm
@evidence
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Fuddman
6/5/2021 06:38:23 pm
““ To further explore the evolution of SL-CoV from Zhoushan, two complete genomic sequences of the representative bat-derived CoVs were generated by sequencing several overlapping amplicons. Specifically, sequences were generated from the following samples: SL-CoV ZXC21 (MG772934) bat that was extracted from a sample procured in July 2015, and SL-CoV ZC45 (MG772933) bat that was extracted from a sample procured in February 2017.
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PETER ROSS
6/5/2021 08:25:40 pm
I'll add my two cents and second that.
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Errata
6/8/2021 02:30:36 pm
@Evidence
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Errata
6/8/2021 02:32:28 pm
> "December 2019 tMRCA [..](I wonder, how could that late tMRCA be realistic for you?)"
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Errata
6/8/2021 02:34:03 pm
>> "Considering the long evolution time implied by the virus sequence differences[..] The first pangolin paper could not lay the foundation for a natural spillover story that would stand the test of time."
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Errata
6/8/2021 02:38:26 pm
@Evidence
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check this
6/10/2021 02:11:44 am
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3863213
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check this
6/10/2021 02:20:05 am
Differential enrichment ofyeast DNA in SARS-2CoV-2 and related genomes supports synthetic 3origin hypothesis (Andreas Martin Lisewski)
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Fuddman
6/11/2021 08:09:02 am
The writer is a flake.
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Errata
6/11/2021 11:46:31 am
@check this
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Errata
6/21/2021 10:00:43 am
So I'm back from the yacht club staring up the boarding ramp. Something smells and I'm looking for what is upwind. To find where guilt lies, look first at whoever is making accusations. What is this from Xu Dezhong and the CCP?
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Errata
6/21/2021 11:07:00 am
Nah, I'm going back to my barstool at the yacht club. It does not make sense that the CCP would without a vaccine purposely risk a danger like the first SARS virus. Such a high kill rate as SARS had would have been seen as a personal threat to decision makers without a vaccine. It does not seem plausible that the CCP or anyone else released the first SARS virus as a bioweapon. It does not seem that the CCP had a vaccine because the researchers working with the virus were not vaccinated. After two lab leaks, in Beijing of all places, the lack of vaccination is manifest. My opinion now is that Xu Dezhong introduced this argument as a rhetorical ploy hoping it would motivate his countrymen to take his ideas on biowarfare seriously.
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nonameneeded
6/10/2021 06:19:21 pm
Another scandal coverup in the works. Fauci's pet vaccines, the mRNA vaccines, apparently cause quite a bit of heart inflammation in young people, especially males.
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David Rivard
6/16/2021 09:51:07 pm
@errata, your general assessment concurs with many Indian researchers. Incidentally, much Indian media has reported consistent research from scientists writing about bio-warfare release (WION, Republic News et al). India being the critical (shall I say allied?) link with the west - and a key target for Chinese expansion in Asia, has certainly suffered more than any other Chinese neighbor. NY attorney Ravi Batra has been the most direct, yet eloquent participant in a great series about covid origin in the many discussions hosted by Republic News. Batra says China's current indisputable war with the west was initiated with a geographically controllable but genomically different September or so release. Later in December 2019 there was a different variant released to the world. Some of the researchers and clinicians in the discussions cite that general Indian ethnicities have been particularly vulnerable, but only from their Indian geographies. The same ethnicities in Pakistan, were largely unaffected by India's latest surges and variants. We must also remember that if origin research reports were highly edited, what about other "assumptions" drawn from the same publications - particularly methods of infection and virulence. Again, those certain scientific publications are citing some variants to be over 15 times more infectious, but that is not consistent with the Indian/Pakistan experience.
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Errata
6/19/2021 01:09:03 pm
Ravi Batra is more gracious than I can bring myself to be. As for his diplomacy, perhaps he is wiser than I. On his science, I have a small objection to a minor point. Batra says that since the coronavirus is becoming more dangerous, it must be unnatural. This is based in the idea that viruses naturally evolve to become milder. I keep hearing this idea expressed by others as well although usually in the form of a conviction that the CoV2 crisis will go away eventually on its own. This is not correct; viruses evolve to spread more effectively. Sometimes they become milder as a result. Although it is true that a virus that disables its victim quickly and therefore suffers from a loss of contagiousness evolves to disable them less quickly, this does not pertain to CoV2. When humans get sick they care for each other. What benefits CoV2 is that this period of care be as long as possible. As we get better at keeping victims alive, CoV2 benefits from countering that by making the victims sicker so as to prolong the period of care. After a long battle with its host and doctors, CoV2 has been evolving to survive despite them. The dangerous new variants are coming from late stage victims after long hospitalization and are likely leaking out through hospital staff or waste. That it is becoming more dangerous is not a legitimate argument in favor of a lab origin.
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PETER ROSS
6/17/2021 02:55:40 am
@nerd
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PETER ROSS
6/17/2021 02:58:51 am
So then, what is going on in these BSL-4 labs, what do the past 20 years of published coronavirus research represent, did a novel pathogen actually arise from the Wuhan lab (or from a comparable biowarfare outfit located elsewhere), and what is the etiology of these covid syndromes?
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Errata
6/19/2021 11:07:04 am
Dearest Peter, your premise is that the basic techniques and tools of genetic engineering do not work. Furthermore, the scientists who use them are either so incompetent that they do not realize it or so dishonest that they pretend they do. I am sure your posts would be comforting and welcome to the anti-GMO crowd. As much as I find your rhetoric entertaining, might I suggest you find one of their blogs and post there instead of bothering the readers here who clearly think you are being silly.
Nerd has power
6/19/2021 05:24:54 pm
@Peter Ross
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PETER ROSS
6/24/2021 02:47:54 am
Chinese Covid-19 Gene Data That Could Have Aided ...
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PETER ROSS
6/24/2021 02:49:58 am
...cont:
Nerd has power
6/19/2021 05:33:41 pm
Using scientific evidence and logic to trace back and reconstruct the possible sequence of events is powerful. Our recent discussions are largely that, which is really cool. However, we could also look at this in the natural, forward direction of time.
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Jimmy Kudo
6/19/2021 07:14:41 pm
"Honestly, when you look back, the story of civet cats being the intermediate host for SARS-CoV-1 isn’t the most convincing. However, the whole world bought it, completely. Wouldn’t that give the CCP scientists some hope that even a mediocre intermediate story may still sell?"
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Errata
6/21/2021 09:54:14 am
This is the passage in the 3rd Yan Report.
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Errata
7/24/2021 02:41:00 pm
@Nerd
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David Rivard
6/20/2021 08:45:51 pm
As the relevant U.S. commission convenes throughout late 2021, more than a war of words is going on as CCP foreign policies expand in it's Asian neighborhood. The aggression that abets this expansion has definitely ramped up during 2020 and onto today, while these neighbors continue to experience "THE Covid-19 entity" but all at different severity levels.
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David Rivard
6/21/2021 06:17:38 am
So although the CCP has orchestrated an almost flawless coverup, what can be said about the U.S. popular media and institutional science contributors who were lulled into silence during an entire election year as the world suffered and depended upon their advice?
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nonameneeded
6/23/2021 05:26:00 pm
I'll just leave this here:
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nonameneeded
6/23/2021 05:32:37 pm
Coincidence much?
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evidence
6/26/2021 06:06:37 am
Re: Reply to Errata's further concerns regarding biowarfare accident scenario, and putative early (August/Sep 2019) infections [Errata 6/8/2021 02:30:36 pm, responding to evidence 6/2/2021 05:20:43 am]
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evidence
6/26/2021 06:13:02 am
(part 2)
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evidence
6/26/2021 06:19:20 am
(part 3)
evidence
6/26/2021 06:25:22 am
(part 4, reply to Errata 6/8/2021)
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evidence
6/26/2021 06:35:04 am
(part 5/5)
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Nerd has power
6/27/2021 04:59:16 am
@evidence
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Nerd has power
6/27/2021 05:36:18 am
George Fu Gao (director of Chinese CDC) and colleagues very recently published a Cell paper, reporting the crystal structure of RaTG13 RBD in complex with human ACE2.
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charly
7/16/2021 02:05:09 am
This is an interesting turn of events indeed. Im glad people like you takes time to dig in. The intensity of the pandemic, and the international concern, makes me hope we will eventually be able to figure out exactly what happened, but my expectations are not so high.
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Fuddman
6/27/2021 12:53:41 pm
Without a sufficient number of COVID dead bodies, covid would not exist as a threat.
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alex
6/28/2021 08:25:56 am
If the sequences posted by Shi and Zhang are fakes, everything that follows too, RP-PCR, etc, everything.
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Fuddman
6/28/2021 01:32:33 pm
"Why was Zhang able to risk this game with the overwhelming consequences it could bring? "
Fuddman
6/28/2021 01:37:30 pm
Strange, don't you think?
alex
6/29/2021 07:57:25 am
Strange, don't you think?
alex
7/19/2021 02:30:25 am
@Fuddman
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alex
1/19/2022 09:26:58 am
@Fuddman is not still reading this blog.
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evidence
6/28/2021 05:26:37 am
Re: (1) Reply to post by Nerd [Nerd has power 5/30/2021 07:21:07 am] in response to my earlier post specifically about Liu pangolin paper timing [evidence 5/29/2021 05:30:19 am], MERS drills, Bloom sequences, Shi
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evidence
6/28/2021 05:31:09 am
(part 2)
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evidence
6/28/2021 05:35:40 am
(part 3)
evidence
6/28/2021 05:38:33 am
(part 4)
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evidence
6/28/2021 05:50:39 am
(part 5)
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evidence
6/28/2021 05:57:22 am
(part 6/6)
Thank you brave nerd!
6/28/2021 06:41:38 pm
This blog and comments are revealing. Unlike virtually everything else on the internet, or at least everything addressing political or news topics, there is real information being posted here by specialists who understand it.
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David Rivard
6/28/2021 08:19:31 pm
I know, this all makes our (science) job much more difficult. While all directions point to bio-warfare, there are so many linked consequential co-conspirators, including Facebook, Twitter, Utube, U.S.gov et al it becomes easy for the CCP to logically point in any direction, but it is interesting the co-conspirators are not pointing in China's direction.
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John Kelleher
7/2/2021 07:37:32 pm
Definitely what the recent bloggers have felt. You especially did not lower yourself to the distraction on the site.Thanks for making me confident in my perspectives.
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Nerd has power
7/3/2021 03:17:15 pm
@evidence
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Xoco Latte
7/12/2021 12:44:55 am
Dear Nerd and All,
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Errata
7/24/2021 02:48:54 pm
@Xoco Latte
Errata
7/24/2021 03:21:22 pm
@evidence & Nerd
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David Rivard
7/12/2021 01:01:30 pm
@Xoco Latte
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Nerd has power
7/17/2021 12:12:34 pm
Don't know anyone paid attention to this, but the original three Yan reports were closed on July 16th, 2021. Accesses to the full articles are no longer allowed at the old web links. It was the Rule of Law Foundation and Rule of Law Society, the previous honorary affiliation of the Yan authors, that requested such closure. It was done under the direction of Miles Wengui Guo.
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Nerd has power
7/17/2021 12:14:46 pm
DOIs, not COIs. I guess I have been reading too much Daszak news lately :)
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PETER ROSS
7/17/2021 12:40:49 pm
The thing is that all these nasty dudes from Fauci to Daszak to Baric to Gates are operatives of sorts, not the terrorist kingpins.
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Errata
7/24/2021 02:52:35 pm
@Peter Ross
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David Rivard
7/23/2021 08:54:57 am
This from Nature Medicine
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PETER ROSS
7/24/2021 02:49:12 am
'The variants of these corona quasispecies over time must always be random!'
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Errata
7/24/2021 03:03:36 pm
@Peter Ross
Errata
7/24/2021 02:56:32 pm
@David Rivard
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Errata
7/25/2021 04:27:54 pm
@David Rivard
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babstar
7/23/2021 10:27:14 pm
Personally I don't lean toward the bioweapon hypothesis, I'm in the leak camp.
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Errata
7/24/2021 03:43:05 pm
@babstar
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Errata
7/24/2021 03:54:40 pm
@evidence, response to (6/2/2021 05:20:43 am)
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Errata
7/24/2021 03:56:37 pm
2) "another concern I do have by trying to sell intentional release without having all convincing evidence for myself: If the 'intentional release scenario' will NOT be able to be sold to the wider public (...), then a lot of deniers (...) have a quite easier play to refute the man-made origin facts all together. Those conspirators could get back the upper hand more easily."
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Errata
7/24/2021 03:58:30 pm
4) Your itemized list:
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Errata
7/24/2021 04:00:45 pm
c) "Pekar approach has logical pitfalls"
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Errata
7/24/2021 04:03:39 pm
g) "I do NOT consider any statistical approach as a valid argument for the pre-tMRC time window"
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Errata
7/24/2021 04:06:20 pm
5) Some words about the Pekar et al. paper.
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Errata
7/24/2021 04:09:19 pm
6) Summary of our discussion of the first pangolin paper by Ping Liu et al.
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Errata
7/25/2021 07:31:14 am
I keep hearing that the bioweapon attack interpretation is a crazy conspiracy theory. It is not. We live in the age of the designer virus. The equipment is readily available and the techniques published in scientific journals. Therefore a bioweapon attack is no longer even limited to sophisticated nation states. Pandemics can happen naturally but
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Errata
7/28/2021 05:08:43 pm
https://www.thegatewaypundit.com/2021/07/report-deliberate-release-covid-19-chinese-military/
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Nerd has power
7/31/2021 12:36:09 pm
@Errata
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David Rivard
8/1/2021 09:37:30 am
"The truth will set you free", at least from constituent suspicions. If your constituents know the truth, you will get universal compliance with the defenses you need to defeat the virus. The choice should also be pretty clear about who would be the preferred dominant power. Their trajectory is now well established.
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David Rivard
8/4/2021 10:15:40 pm
https://economictimes.indiatimes.com/news/defence/view-covid-19-chinas-bioweapon-warfare-strategy-and-global-security/articleshow/83321527.cms
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Nerd has power
8/8/2021 06:03:24 am
https://www.thegatewaypundit.com/2021/08/chinas-next-dangerous-bioweapon-u-s-helping-build/
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Errata
8/9/2021 11:51:39 am
Ohio Republican Rep. Jim Jordan is giving FBI Director Christopher Wray until Aug. 9 to answer the House Judiciary committee questions about Dr. Li-meng Yan's claims.
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Errata
8/9/2021 11:55:06 am
https://m.youtube.com/watch?v=MoonDWvi1T8
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Xoco Latte
8/10/2021 02:28:49 am
Well, more and more so, it seems as if the FBI (and other US intelligence agencies as well as authorities) are trying very hard to cover up an original cover-up by the Chinese, partly because of massive American involvemnet of the GOF acitivities and funding that help creating this monster coronavirus.
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David Rivard
8/10/2021 08:35:11 am
As a global scientific community pursuing the common cause of understanding covid entities through genetic sequencing, I was astounded that Dir. Wray did not share this information with the other agencies and will not develop a policy because "EACH AGENCY WILL HAVE THEIR OWN CONCLUSIONS". Even in the face of "AND EVEN TO TRY TO PRESENT A FAKE GENOME SEQUENCE AT THE BEGINNING OF THESE DEVELOPMENTS?")
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David Rivard
8/12/2021 10:36:40 am
There are attempts, at least to collate articles:
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David Rivard
8/12/2021 10:48:46 am
The WHO situation reports and data tables being wholly basic. Still based upon mortality vs. immediate survival.
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David Rivard
8/13/2021 11:26:25 am
OK, I would like to propose a question and answer period for this site. Is it true that after a few months, the complete genomic sequence of C-19 becomes "extinct".
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david rivard
8/25/2021 11:36:57 am
Top down operations still prevail as all countries pragmatically strategize with WHO information. Presidents only see liabilities in lending "hearsay" to their political repertoire.
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nonameneeded
8/26/2021 09:41:29 am
I'm surprised at the lack of comments on all the breakthrough infections going on, as well as the call for every 6-8 month boosters. Here's an interesting preprint from Israel:
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David Arthur Rivard
8/26/2021 12:52:27 pm
Yes, thanks for the reply @nonameneeded. As with all aspects of the pandemia, including obviously the vaccines, and now with the variants, the obvious questions are, hmm, still no raw clinical data delivered to the WHO by the CCP. Israeli, South African, Indian, European and US variants (Western variants) doing their job, and as earlier extrapolations from this site has predicted about the debilitating design of the disease, we finally have some attention about so called "long covid".
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Errata
8/26/2021 06:54:17 pm
@nonameneeded "'SARS-CoV-2-naïve vaccinees had a 13.06-fold (...) increased risk for breakthrough infection with the Delta variant compared to those previously infected...' Natural immunity is clearly superior against the variants. The basis for vaccinating low risk individuals such as people in their teens and 20s is NIL."
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Errata
10/29/2021 06:14:29 pm
Here is the declassified DNI (pronounced deny) report in full.
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Errata
8/27/2021 10:44:17 am
@nonameneeded
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Bro
9/2/2021 07:08:13 pm
Recent studies have shown T cell cross-recognition of SARS-CoV-2 and common cold coronavirus spike proteins. Therefore these current vaccines could cause unintentional over reaction to simple common cold with much higher inflammation . Are scientist become so dummy these days? This may also explain the so called breakthrough infection given the inaccuracy of pcr test?? See this paper:
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Errata
9/6/2021 03:22:11 pm
@Bro
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Nerd has power
9/5/2021 09:14:58 am
Thank you, Nonameneeded, for the Israel preprint article. I think it speaks potently about the superiority of natural immunity over vaccine-induced immunity. The fact that the recent vaccine mandates make no mention of natural immunity is just not right. Of course, I'm not a fan of the mandate to begin with.
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Nerd has power
9/5/2021 10:05:56 am
What is our chance of reaching herd immunity through vaccination? My opinion is that we will not be able to. My main argument is that the CCP will make sure that our vaccines don't work.
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Bro
9/5/2021 07:27:23 pm
How they can release a variant in specific region in large amount? Such as in Iran, India and brazil? Are they using drone or by commuting agents? Or simply polluting the water? These are all direct terror act using invisible enemy!
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Nerd has power
9/11/2021 05:03:23 am
I don't think you need to use any specific tools to "spray" the novel variants; they are viruses that can transmit on their own. You may just seed a highly transmissible variant in a few individuals or a single person and it would just take off.
David Rivard
9/7/2021 12:52:52 pm
"Killing us softly" comes to mind. When I first read the aforementioned Salk study (like most studies, by the way, came about with empirical observations), my knee jerk reaction was to email my sister, who is a 50 year ER nurse who observes long-covid on a daily basis. The e-mails title was "CV underpinnings of the C-19 spike protein. It helps explain "longcovid" and begs for new testing protocols."
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David Rivard
9/8/2021 10:36:26 am
I hesitate to disclose partisan politics in a scientific discourse that has been so useful to a scientific community. By default, even as clinicians, we have turned into para-virologists (my apologies to the many professional virologists who have selflessly and astutely contributed to this site.
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Nerd has power
9/11/2021 05:18:24 am
I probably share a little less despair with you, David. I don't believe the CCP will win this "ultimate war" (Xi Jinping's own words - "终极之战"). I think that is more of their own illusion. However, the course of this war could be a little long. I am having the impression that majority of the world either refuses or is denied access of the objective truth of this pandemic. As a result, their wakening would be delayed, after a lot more and a lot longer suffering. The pain and various losses that people experience, which will accumulate substantially over time, will help build the world's determination to crush and eradicate the CCP. This process may be painful to watch and even endure personally, but may be inevitable.
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Errata
9/24/2021 05:36:30 pm
The path to victory is through knowledge. Public outrage at China will demand action. Trade sanctions and a pivot to Taiwan are practical. This hits the new rich in mainland China where it hurts. Xi Jinping has already been crossing swords with his financial elite. He is underestimating his opposition. When he is brushed aside, policy changes will be as dramatic as the change from Trump to Biden. I predict the CCP will hang on but use blame for the pandemic as an excuse to clean house and purge Xi Jinping loyalists.
TooNewb
9/22/2021 01:26:47 pm
I'm not qualified to carry water to this fire but wanted to see what you all thought of this preprint: https://www.researchsquare.com/article/rs-871965/v1
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david rivard
9/24/2021 10:02:21 am
At this stage there should at least be acknowledgements from several authors in "Competing Interests". The scientific community has identified the C-19 genome almost two years ago. It has logically induced many studies as a pandemic. Substantial and consequential financial gains by many of these authors have been uncovered only after much exhaustive work, which additionally required FOIA requests. In it's evident paradigm changing manifestation at many levels, there should by now be some attention to defining "Competing Interests" among every related scientific report.
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Errata
9/24/2021 05:16:15 pm
What? Bats with human ACE2? A bat virus that is better adapted to humans than bats? Someone sneezed on their Vero E6 cultures. This comedy comes direct to us from the CCP subsidiaries of Laos.
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Nerd has power
9/26/2021 05:17:07 am
One thing obvious from this paper is that, aside from the new viruses they "discovered", they only used the CCP's fake viruses in their phylogenetic analyses. It's so exclusive that I giggled when I first saw it. Of course, on the first look, one would be amazed at how many natural cousins SARS-CoV-2 has (who cares that all of these were discovered after the pandemic started although the CCP has been diligently surveilling for wild coronaviruses for two decades). However, if you dive a little below the surface, it cannot be more obvious that this bias is very intentional and the design of the manuscript (or we could say, of these new viruses) is to continue to fabricate a path of natural evolution for SARS-CoV-2.
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TooNewb
9/27/2021 10:55:22 am
Nerd,
david rivard
9/24/2021 09:34:20 am
https://www.rapidmicrobiology.com/news/200-recombinant-sars-cov-2-variants-bank-for-vaccine-research
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Errata
9/24/2021 05:50:59 pm
@Nerd
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Errata
9/24/2021 05:52:50 pm
On the topic of vaccine side effects, whatever happened to Biovacc19 by Immunor? They made an effort to avoid the issues that trouble you about vaccines such as autoimmune disease. This was discussed earlier (6/8/2020 08:15:21 pm).
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Errata
9/24/2021 05:54:49 pm
NERD: "What is our chance of reaching herd immunity through vaccination? My opinion is that we will not be able to. My main argument is that the CCP will make sure that our vaccines don't work."
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Errata
9/24/2021 05:56:35 pm
NERD: "look carefully at the mutations of these two variants (...), you will be amazed at how they followed the same 'concepts' but contain very different mutations at a critical location...the mutational patterns here in Delta and Kappa are very different and have no evolutionary relationship with each other (...). Yet, these two variants appeared around the same time in India. More interestingly, both variants carry the P681R mutation, turning the furin cleavage site from PRRA to RRRA."
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Errata
9/24/2021 05:58:55 pm
As to future dangers, fatalities from CoV2 are often due to the victims having mutations in the interferon system. This hints at one reason why CoV2 has such a low mortality rate compared to SARS. It also foreshadows what will come when full functionality is restored to ORF6 and ORF8. Then everybody will be in the dire position that only those with defective immune responses are in today. It is interesting that Vero E6 passaging leads to a virus losing its ability to suppress the interferon system because there is no natural context where selection would give this result. The use of Vero E6 cells is common practice. It is not quite a smoking gun, more like a ballistics match, but it supports a lab origin because deleterious mutations accumulate without purifying selection and Vero E6 cells have no interferon system to suppress. Evidence made a prediction that I think will turn out to be correct.
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Errata
9/24/2021 06:00:30 pm
NERD: "Finally, one thing that always puzzles me is why would a bunch of frontline doctors promote cheap drugs like Ivermectin and HCQ for early treatment of COVID...these doctors could live a much better life if they don't advocate for the cheap drugs. After all, majority people will believe the MSM and the experts who have significant potential COI than believe these frontline doctors, who appear, as least to me, to be free of any COI."
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Nerd has power
9/26/2021 08:46:33 am
@Errata
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Nerd has power
9/26/2021 08:51:59 am
Next, I want to comment on the autoimmune disease on this 27-year-old young man.
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Nerd has power
9/26/2021 08:56:40 am
By arguing against vaccine mandate, I am not suggesting that we stop fighting and instead quit. I just don’t think vaccines mandate is the right way of fighting. Don’t forget that vaccines lose effectiveness facing new variants –-- it does not block the punches effectively. Delta showed you this already. In fact, new variants vs. vaccines is CCP’s favorite way of playing this game. They always have the upper hand here and can keep hurting you.
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Nerd has power
9/26/2021 09:02:25 am
Speaking of HCQ and ivermectin, please be aware that the media smearing them are the lefty ones that are more pro-CCP.
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Nerd has power
9/26/2021 09:05:48 am
Lastly, on the possible motives of the CCP in developing new variants, I want to suggest this one:
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David Rivard
9/26/2021 07:58:30 pm
“In their 'x' rays, nasal swab tests are very often negative for covid-19, Delta strain, and there are more and more false negative results from nasopharyngeal tests. Which means that the virus directly attacks the lungs, ”wrote the specialist who identifies herself as Dr. Arevalo.
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David Rivard
9/29/2021 03:50:39 pm
As I read through the latest @natureresearch article this morning; "Understanding the T-Cell Response: SARS-CoV-2 variants and vaccine immune response", "SARS-CoV-2 variants are escaping neutralizing antibody responses, but have not escaped the T-cell response - recent vaccine research case studies", I naturally wondered if NIH is considering that: 1) if created in a lab so completely ready for infection in humans (weaponized?) and, 2) if funded by the U.S. and France and, 3) if accidently released (prematurely?) but intentionally concealed (wanting the same effect as a deliberate launching?) and, 3) if a conflicted global scientific and governance community is unable to pressure PLA labs for information much less monitoring or closure for this type of research, then, isn't it logical that they would continue to use the funded knowledge of the global community to continue refining their work?
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Errata
10/1/2021 06:56:46 pm
@David Rivard
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chantily
10/3/2021 03:47:00 am
@Nerd @errata
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Nerd has power
10/3/2021 08:17:16 am
Interesting thoughts. We have discussed about this paper briefly, mostly on how these "new" viruses could easily be results of fabricated viral sequences or samples with artificial viral genetic materials mixed in. Your hypothesis put this at another level -- the CCP could inoculate the artificial coronaviruses back into bats and subsequently "discover" the "natural" existence of such viruses, say in Laos.
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Errata
10/5/2021 10:34:35 am
@chantily
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Errata
10/5/2021 10:40:30 am
恐怕正是这批美国龙虾,打开了华南海鲜市场疫情的潘多拉盒子。
chantily
10/6/2021 05:41:31 pm
@errata
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Errata
10/9/2021 07:08:39 pm
@Chantily
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Nerd has power
10/10/2021 05:11:23 am
I saw the lobster claim too. The CCP is trying to grab onto anything that it can. I think they know that such a story can't fly, but they may hope that it will complicate the issue. In other words, they do not expect that they could fool the whole world with this story, but fooling a fraction of the population is still good (in their eyes) to make the water murky and make a consensus impossible. Of course, like Errata pointed out, the CCP mainly wants to fool the Chinese people. Otherwise, who would fight the US to protect the CCP?
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Jennifer Hay
10/10/2021 05:00:30 pm
Dear Nerd, What do you think of the hypothesis that the SARS-CoV-2 virus is fabricated code, much like you assert for the RATG13? Could you point me to some references for your answer?
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evidence
10/13/2021 01:59:58 am
Dear Jennifer,
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Nerd has power
10/16/2021 05:37:21 am
Thank you, Evidence, for the explanation.
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evidence
10/13/2021 10:47:35 am
(Reply to Errata)
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evidence
10/13/2021 10:55:17 am
(Reply to Errata, part 2)
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evidence
10/13/2021 11:02:52 am
(Reply to Errata, part 3)
evidence
10/13/2021 11:35:31 am
(Reply to Errata, part 4)
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evidence
10/13/2021 11:44:32 am
(Reply to Errata, part 5)
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evidence
10/13/2021 11:51:03 am
(Reply to Errata, part 6)
evidence
10/13/2021 11:57:28 am
(Reply to Errata, part 7)
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evidence
10/13/2021 12:01:48 pm
(Reply to Errata, part 8)
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evidence
10/13/2021 12:07:24 pm
(Reply to Errata, part 9)
evidence
10/13/2021 12:11:17 pm
(Reply to Errata, part 10)
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evidence
10/13/2021 12:18:09 pm
(Reply to Errata, part 11)
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evidence
10/13/2021 12:25:32 pm
(Reply to Errata, part 12)
evidence
10/13/2021 12:30:18 pm
(Reply to Errata, part 13)
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evidence
10/13/2021 12:34:52 pm
(Reply to Errata, part 14)
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evidence
10/13/2021 12:41:11 pm
(Reply to Errata, part 15)
evidence
10/13/2021 12:45:06 pm
(Reply to Errata, part 16)
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evidence
10/13/2021 12:50:45 pm
(Reply to Errata, part 17)
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evidence
10/13/2021 12:55:46 pm
(Reply to Errata, part 18)
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evidence
10/13/2021 01:01:26 pm
(Reply to Errata, part 19)
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evidence
10/13/2021 01:06:41 pm
(Reply to Errata, part 20)
evidence
10/13/2021 01:11:56 pm
(Reply to Errata, part 21)
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evidence
10/13/2021 01:17:33 pm
(Reply to Errata, part 22)
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evidence
10/13/2021 01:22:51 pm
(Reply to Errata, part 23)
evidence
10/13/2021 01:29:09 pm
(Reply to Errata, part 24, final)
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Nerd has power
10/24/2021 05:18:26 am
@evidence
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Errata
10/25/2021 03:49:01 pm
@Nerd
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Nerd has power
10/30/2021 05:11:19 am
I do not agree. In any case, it is just wrong to put your own name under someone else's work without asking for permission of any kind. He also put Rule of Law Foundation and Rule of Law Society as Dr. Yan's affiliation there. However, we have clearly indicated in the updated Yan reports that we are not affiliated with these organizations and our work was independent and not sponsored by them.
Nerd has power
10/24/2021 05:24:32 am
Now to answer this question of yours:
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Nerd has power
10/24/2021 05:31:57 am
...... Or we could say that an accident could not be predicted with such details. In my opinion, these MERS drills alone lift the intentional release hypothesis (IRH) way above the bioweapon accident (BWA) theory.
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PETER ROSS
10/24/2021 06:02:34 am
Those sticky thorns on a stick repetitively shoved up the nose to scrap off human cells from the mucosa isn't for fishing out a few 50 nt RNA fragments from young, healthy, asymptomatic individuals - for a flu-like illness with an IFR of roughly 0.2% .
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David Rivard
10/24/2021 01:23:29 pm
And let's not all forget that it was the timing of this release that brought us all to the site in the early months.
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David Rivard
10/24/2021 01:20:32 pm
Yes, the major media themes being:
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Xoco Latte
10/29/2021 02:25:29 am
Disclaimer: I did not disappear, just became a bit more sour and still...
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Errata
10/25/2021 04:00:22 pm
Fauci stepped in a meadow muffin: "molecularly impossible" LOL! This is going to stink up his science credentials and waft after him for years.
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David Rivard
11/3/2021 08:41:47 pm
St. Paul Pioneer Press 11-3-2021
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Xoco Latte
11/4/2021 03:07:28 am
This seems like the most unpredictec, yet most fearsome feature of this synthetic chimeric coronavirus strain (or family?), something never has been seen before in a coronavirus, or, perhaps any viruses.
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Nerd has power
11/7/2021 06:14:30 pm
What a chilling finding. As I have mentioned in an earlier post (10/10/2021 05:11:23 am), in the PLA's 2015 blueprint for the "contemporary genetic weapon", it was planned that the artificial pathogen should ideally be carried by animals in the enemy's habitat. Such animal hosts will be a constant reservoir of the pathogen; through close contact, animals will constantly pass the pathogen onto humans.
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Lawrence
12/5/2021 02:42:47 pm
I'm commenting about the animal reservoirs, as in the deer herds. Deer and Elk in several areas suffer from a wasting disease, and it is quite transmissible among them; a wildlife biologist described it to me as a prion disease. I haven't heard much about people catching it except by butchering harvested animals. Hunters are savvy about this disease; some states have culling and disposal programs. I do not worry about the CCP FauXi-Gates viruses in wildlife, or domestic animals. Usually, humans have to work at it to acquire animal diseases. Sure, there is rabies, pemphigus, hanta, plague, tularemia and so forth. As far as domestic animals, confined feeding animal operations and practices concentrate and increase disease transmission occurrences. Bovine mammary virus is found in human breast cancer; it is extremely transmissible between cows in crowded pens. USDA and the meat animal industry hasn't bothered developing a vaccine and medical research isn't talking loud enough. The CCP FauXi-Gates virus isn't the threat, the shots are. Humans can be treated easily and inexpensively, and despite the constant obstacles, propaganda, institutional abuses, intimidation, etc., we are. Part of the "Plan" involves mass slaughter of "animal reservoirs;" they will reach for those animals that feed us, comfort us and support economies. The actual fatality rate from the virus, the CDC admits, and you can find it, it's in table 3 or 5, sorry I don't have it at immediate hand, 5% of the Johns Hopkins numbers. Too many of that 5% are from "treatment" with ventilators, remdesivir, hospitals' refusals to use the IVM/HCQ etc protocols. I am amazed how IVM/HCQ protocols are helping many injured from the shots.
PETER ROSS
11/4/2021 03:34:30 pm
Well done Nerd!
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11/7/2021 05:10:50 pm
thank you for nice information
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David Rivard
11/19/2021 09:18:23 am
https://scitechdaily.com/tracing-covid-back-to-origin-many-variant-strains-were-already-present-before-the-first-known-cases-identified-in-china/
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chantily
11/26/2021 06:20:09 am
From the news today... The real question, natural or engineered mutations? Anyone here have any thoughts on that?
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Xoco Latte
11/28/2021 04:35:15 am
I am not convinced in either direction. That means, in theory, it's possible for a coronaviral strain developing on the field in the middle of a pandemic to accumulate certain advantageous mutations. I have no idea, if there's any empirical (or for that matter, hypothetical) upper limit for such mutation frequency. To be able to acertain a natural evolution of this specific variant, one must be able to find the inherent zero case and its ancestral case(s), and get as many sample as possible to see all the existing variants inside those individuals.
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evidence
11/29/2021 02:50:10 pm
Re: Worobey equally CORRUPTED - and possibly only a little bit more shrewd (for example as compared to Andersen): ignorance still is bliss.
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evidence
11/29/2021 03:02:45 pm
(part 2/2)
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Nerd has power
12/30/2021 05:21:39 pm
Sorry for having been silent lately. It's been a little hectic. If you are paying a visit, thank you. It's nice to communicate with you, again.
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PETER ROSS
12/30/2021 11:16:01 pm
Happy New Year 2022 to Nerd & To All who visited and contributed!
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evidence
12/31/2021 09:34:51 am
Of note, for anybody who has something (important) to contribute, but would still feel largely unprotected (for example those individuals being involved in some institutional context), here are some instructions:
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David Rivard Arthur Rivard
1/13/2022 10:43:54 am
Kamala Harris commented that this time is the equivalent of WW’s l and II and that we all need collective efforts and sacrifices to follow the mandates of our government. Fauchi’s heart felt impunity as he testifies in Congress (in terms of his seeming culpability to develop the virus), and the uniform cooperation of America’s IC’s and social medias, concludes that this administration’s higher goal is to keep the world out of a WWIII. The U.S. and traditional allies are obviously deploying only defensive tactics, depending primarily on vaccines, to defend it’s citizens. They have concluded early on that they will let China have what it wants, within the bounds of how the U.S. government can explain China’s expansionist rationale to, primarily, U.S. citizens. If the U.S. fails in their primary strategy (mollifying China), then we will experience more devastating variants. Expect prudent posturing along every step of the way to avoid conventional warfare, which is still the weapon mind think of the West. China has gained even more moral high ground with global community citizens, as their governments cover China's real sin of developing and releasing the first, and possibly subsequent, bio-weapons.
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David Rivard
1/13/2022 11:35:32 am
At the risk of sounding like a Robert White poet, I would like to amend my above comments per the following:
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Nerd has power
1/29/2022 11:38:08 am
Spot on, David! Especially on the possibility of CCP releasing other bioweapons and their not-so-short-term goal of achieving global dominance.
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David Rivard
2/1/2022 08:11:17 pm
It's a shame to completely abandon this site when the party is just getting started.
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aelfwine
10/20/2022 04:02:47 pm
The truth is going to come out. Thanks for all you did in the early days Nerd has power.
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aelfwine
10/20/2022 04:13:35 pm
The truth is going to come out. Thanks for all you did in the early days Nerd has power.
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evidence
10/24/2022 07:57:38 am
Re: Recent Bruttel Restriction enzymae analysis paper: who deserves also credit?
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evidence
12/15/2022 06:32:34 am
Re: Twitter censoring of Daoyu Zhang revisited (initiated during the ‘pre-Musk’ era, around July 15 2022) - in the light and context of the LATE stage of the Covid origin information war
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evidence
12/15/2022 06:45:17 am
(part 2)
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evidence
12/15/2022 06:53:51 am
(part 3)
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12/20/2022 03:58:40 pm
İnstagram takipçi satın almak istiyorsan tıkla.
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PETER ROSS
12/21/2022 09:40:25 am
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1/7/2023 08:35:22 pm
100 tl deneme bonusu veren siteleri öğrenmek istiyorsan tıkla.
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1/25/2023 12:30:43 am
Thanks for sharing such a informative blog! We are continuing our mission to inspire future talent in the governance profession through exciting, interactive and informative sessions with some of the UK’s biggest and best organisations.
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Errata
1/30/2023 12:37:40 am
Congratulations! Congress has validated key parts of the Yan reports.
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Nerd has power
4/4/2023 08:40:52 pm
Sorry for being silent for so long. I don't think this site is being visited by many anymore. It has lived its life and hopefully served its role -- whatever that is.
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BlessYou
10/24/2023 03:58:55 pm
I hope you are doing well! Thanks for your blog and I believe your grandma is proud of you! I am from China but now I live in US. At the beginning of this pandemic I had already read your article. I trust you more than other sources. 好人一生平安!感恩
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From USA
6/12/2023 06:19:38 pm
Don't know if the blog owner will see this, but I want to tell him/her that this blog was extremely valuable. I and others who are not biology PhDs can't follow all (or nearly any) of the biology papers cited but we could see that we were not being told the truth. This blog provided a much stronger level of information than the average person in English-speaking countries could get for themselves in the past 2-1/2 years. -
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6/29/2023 05:37:48 pm
En iyi ağrı ilan sitesi burada. https://agri.escorthun.com/
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David Rivard
11/2/2023 10:02:48 am
Yes, unfortunately the Nerd's theme maintains relevance. The blog continues to evolve with a few embers, surviving even the damping winds of time, wars and societal dysfunctions. It has certainly layed, not a, but the template for exploring the underlayment of "strategic science" deployments. It deserves mention in scientific journals for this contribution, especially in light of overwhelming public (and yes, even familial) criticism. Sociological and political lessons went hand in hand with a need to get to genomic, clinical and infectious truths. Paradigm changes brought about by a previously unthinkable disaster.
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David Rivard
11/2/2023 10:17:05 am
Like the Robert White poet; Yes, Maybe even with a little dose of fitting into the otherwise failed deep states ambitions.
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1/24/2024 04:06:43 am
What scientific evidence supports the assertion that the Wuhan coronavirus is a product of human engineering?
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Errata
1/25/2024 09:57:28 am
@Telkomuniversity
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3/2/2024 10:58:47 pm
What specific scientific evidence supports the claim that the Wuhan coronavirus is man-made, and how has this evidence been scrutinized by the scientific community?
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